35 research outputs found
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Integrating Folksonomies into Cultural Heritage Digital Collections: The Challenges and Opportunities of Web 2.0
In this presentation, the author defines Folksonomy and the advantages and disadvantages of Folksonomy. He begins with a background on information retrieval and changing technologies, discusses trends in technologies, and explains the use of tags and Folksonomy
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Developing the ICT Infrastructure for Africa: Overview of Barriers to Harnessing the Full Power of the Internet
Article on developing the Information Communication Technologies (ICT) for Africa and an overview of the barriers to harnessing the full power of the internet
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Exploration of Adoption of Preservation Metadata in Cultural Heritage Institutions
Paper presented at the 2010 ASIS&T Annual Meeting. This paper discusses preservation metadata and its role in the challenges of long-term access
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Targeted Access for Varied Audiences to Integrated, Heterogeneous Digital Information Resources
Paper accompanying a poster presentation for the 2003 ASIS&T Annual Conference. This paper describes the University of North Texas (UNT) Libraries' Portal to Texas History project, which aims to integrate and ensuer long-term access to large quantities of heterogeneous digital resources from many different institutions
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The Cybercemetery: Prolonging Usable Afterlife
Paper for the 2004 IS&T Annual Archiving Conference. This paper discusses issues related to digital resource management when capturing and preserving web-based, heterogeneous digital materials produced by a variety of software in various versions
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Meeting the Demands of Digital Scholarship: Challenges and Opportunities
Paper accompanying a poster presentation for the 2005 ASIS&T Annual Conference. This paper provides an overall scenario in the areas of aggregating a variety of digital formats, archiving digital content, and innovative uses of digital library technologies
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Revisiting the Evolving Landscape of Open Access and Scholarly Communication
Presentation at the 2018 Annual Conference of the Association for Library and Information Science Education. This presentation contains questions and topics of discussion for the panelists
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Designing Information Communities for the 3D Environment
This abstract describes a panel presentation for the 2002 ASIS&T Annual Conference. The panel provides a summary of current research efforts in 3D imaging technologies, including how metadata fit into the panorama of building information communities
Identification of Candidate Growth Promoting Genes in Ovarian Cancer through Integrated Copy Number and Expression Analysis
Ovarian cancer is a disease characterised by complex genomic rearrangements but the majority of the genes that are the target of these alterations remain unidentified. Cataloguing these target genes will provide useful insights into the disease etiology and may provide an opportunity to develop novel diagnostic and therapeutic interventions. High resolution genome wide copy number and matching expression data from 68 primary epithelial ovarian carcinomas of various histotypes was integrated to identify genes in regions of most frequent amplification with the strongest correlation with expression and copy number. Regions on chromosomes 3, 7, 8, and 20 were most frequently increased in copy number (>40% of samples). Within these regions, 703/1370 (51%) unique gene expression probesets were differentially expressed when samples with gain were compared to samples without gain. 30% of these differentially expressed probesets also showed a strong positive correlation (r≥0.6) between expression and copy number. We also identified 21 regions of high amplitude copy number gain, in which 32 known protein coding genes showed a strong positive correlation between expression and copy number. Overall, our data validates previously known ovarian cancer genes, such as ERBB2, and also identified novel potential drivers such as MYNN, PUF60 and TPX2
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat