Sexuality, Poverty and Politics in Rwanda

Recent legislative developments in Africa have focused international attention on the legal status of lesbian, gay, bisexual and transgender (LGBT) people in the continent. Attempts by various African governments to revise or introduce new legislation on same-sex sexual conduct and marriage, and the response of the international community, has sparked extensive coverage of the associated political, social and cultural controversies. Away from the headlines are several African countries that have never criminalised same-sex sexual conduct and that are outliers to the apparent ‘trend’ of homophobia and of discriminatory legislation in the continent. One of these is Rwanda. Compared with the situation in neighbouring countries, state-sponsored homophobia appears negligible in Rwanda, and violent attacks are minimal. Despite negative reports of Rwanda’s human rights record in areas such as civil and political rights, when it comes to sexual orientation and gender identity, human rights observers consistently report that there is no need for concern. In the international arena, Rwanda has emerged as an unlikely champion for LGBT rights, and domestically has designated sexual orientation as a ‘private matter’. This study explores Rwanda’s relatively progressive position on LGBT-related issues and its implications for Rwandan civil society. It examines the strategies employed by national as well as international actors to advance LGBT rights and to address social and economic marginalisation.UK Department for International Developmen

Sexuality and Social Justice: What’s Law Got to Do with It? International Symposium Workshop Report

In March 2015, the Sexuality, Poverty and Law programme at the Institute of Development Studies brought together over 60 activists, lawyers, researchers and international advocates to critically assess the scope of law and legal activism for achieving social justice for those marginalised because of their sexual or gender non-conformity. Delegates represented a broad range of expertise in the field of sexuality, gender identity, rights and social justice. They included a number of leading lawyers and activists involved in litigating cases of sexual and gender rights in countries such as Uganda, Malaysia, the United Kingdom, Argentina and Botswana. Lawyers and activists shared their experiences of working within this fast developing area of domestic and international law. Discussions also addressed the wider social and theoretical aspects of recent legal developments, contributing to our understanding of the complex relationship between research, knowledge exchange, activism and law.UK Department for International Developmen

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus.

Anthracimycin is a recently discovered novel marine-derived compound with activity against Bacillus anthracis. We tested anthracimycin against an expanded panel of Staphylococcus aureus strains in vitro and in vivo. All strains of S. aureus tested, including methicillin-susceptible, methicillin-resistant (MRSA) and vancomycin-resistant strains of S. aureus, were susceptible to anthracimycin at MIC values of ⩽0.25 mg l(-1). Although its postantibiotic effects were minimal, anthracimycin exhibited potent and rapid bactericidal activity, with a >4-log kill of USA300 MRSA within 3 h at five times its MIC. At concentrations significantly below the MIC, anthracimycin slowed MRSA growth and potentiated the bactericidal activity of the human cathelicidin, LL-37. The bactericidal activity of anthracimycin was somewhat mitigated in the presence of 20% human serum, and the compound was minimally toxic to human cells, with an IC50 (inhibitory concentration 50)=70 mg l(-1) against human carcinoma cells. At concentrations near the MIC, anthracimycin inhibited S. aureus nucleic acid synthesis as determined by optimized macromolecular synthesis methodology, with inhibition of DNA and RNA synthesis occurring in the absence of DNA intercalation. Anthracimycin at a single dose of 1 or 10 mg kg(-1) was able to protect mice from MRSA-induced mortality in a murine peritonitis model of infection. Anthracimycin provides an interesting new scaffold for future development of a novel MRSA antibiotic

Limited impact of big fish mothers for population replenishment

A recent meta-analysis by Barneche et al. (Science 360(6389): 642) show that fish reproductive output scales hypergeometrically with female weight. This result challenges the common assumption that reproductive output is proportional to weight. The implication made is that current theory and practice severely underestimates the importance of larger females for population replenishment. Their example for cod shows that current practice makes an error of 149%. By properly accounting for fish demography we show that the error is maximally on the order of 10%, and in most other fish stocks likely much less.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

Dynamical models for sand ripples beneath surface waves

We introduce order parameter models for describing the dynamics of sand ripple patterns under oscillatory flow. A crucial ingredient of these models is the mass transport between adjacent ripples, which we obtain from detailed numerical simulations for a range of ripple sizes. Using this mass transport function, our models predict the existence of a stable band of wavenumbers limited by secondary instabilities. Small ripples coarsen in our models and this process leads to a sharply selected final wavenumber, in agreement with experimental observations.Comment: 9 pages. Shortened version of previous submissio

A particle model of rolling grain ripples under waves

A simple model is presented for the formation of rolling grain ripples on a flat sand bed by the oscillatory flow generated by a surface wave. An equation of motion is derived for the individual ripples, seen as "particles", on the otherwise flat bed. The model account for the initial apperance of the ripples, the subsequent coarsening of the ripples and the final equilibrium state. The model is related to physical parameters of the problem, and an analytical approximation for the equilibrium spacing of the ripples is developed. It is found that the spacing between the ripples scale with the square-root of the non-dimensional shear stress (the Shields parameter) on a flat bed. The results of the model are compared with measurements, and reasonable agreement between the model and the measurements is demonstrated.Comment: 9 pages incl. figures. Revised versio

Final Interpretation Report of the PHEBUS test FPT0: Bundle Aspects

In this paper, the actual status of understanding of the dominant bundle degradation processes is presented. Here, mainly the results reported in the last years in the Bundle Interpretation Circles organised by JRC/IE and IRSN (Institut de Radioprotection et de Surete Nucleaire, Cadarache) are summarised. For the extensive and detailed computational analyses the commonly used severe accident codes such as ICARE, MELCOR, SCDAP/RELAP and ATHLET-CD are used. For the analysis of fission product release from the FPT0 bundle, specific codes such as SVECHA and XMPR were used as well.JRC.F.4-Nuclear design safet