Chaotic spiral dynamics optimization algorithm

© 2016, World Scientific Publishing Co. Pte Ltd. All rights reserved. This paper introduces a chaotic spiral dynamic algorithm (CSDA) for optimization problems. The algorithm is developed by incorporating the chaotic maps pattern into the original spiral dynamic algorithm (SDA) by replacing the rotational radius in SDA with chaotic map, so as to enhance the search diversity of the algorithm avoid potential trap in local optima. The performance of the algorithm is assessed in comparison to SDA with a set of benchmark functions and PD controller tuning of a single link flexible robot manipulator system (SLFRMS). The results show that the CSDA outperforms the SDA with enhanced search capability and escaping local optima

Study on wing fanning as a signal of sexual response and courtship behavior of Bactrocera papayae

A series of experiments was carried out at the Institute of Biological Sciences, University of Malaya to identify wing fanning as an attraction or signal of sexual response and courtship behavior of Bactrocera papayae. Sexual natures such as signal or attraction and courtship behavior were determined through males and females with modified wings and sensory receptors, respectively. Wing fanning was effective to attract female towards male (42 to 48%) and vice versa (22 to 25%). Sexual attractiveness and signaling by males varied with light intensity. Females were attracted more at 18:20 to 18:55 by frequent wing fanning by males and sharply declined after sunset. Least attraction (10%) was observed by females toward males with modified wings compared to males with non modified wings. Similarly, males were less attracted by females with modified sensory receptors. Significantly, weaker sexual response was found when both the aristae and antennae were removed. Mating rate (12 to 14%) was reduced significantly by males wing removal and clipping (>50%) and wing bases waxed. Modified females mated less than non-modified ones due to the preventive measure of the pheromone receptor. Olfactory signals appear to be more important than acoustic signals in determining whether a female would mate or not. Pheromone along with acoustic receptor modification played a key factor in the success of mating. Acoustic and olfactory signals appear less important when eliminated singly, but combined elimination of olfactory and acoustic signal reduces the mating of females by a greater magnitude.Key words: Attraction, courtship, response, sexual, signaling

Optimal tuning of PD controllers using modified artificial bee colony algorithm

© 2018 Universiti Teknikal Malaysia Melaka. All Rights Reserved. This paper presents an investigation of PD controller tuning using a modified artificial bee colony algorithm (MABC). The main purpose of this work is to apply and investigates the performance of MABC in tuning the PD controller of single link manipulator system (SLMS) in comparison with the original ABC. The objective of the MABC algorithm is to minimize the error by using mean square error (MSE) as an objective function. The proposed algorithm has also been tested in three benchmark functions with different dimensions to checked the robustness of the algorithm in different problems surface. The result shows that the MABC able to tune the controller to their best optimum value

Multi-criteria decision making (MCDM) model for seismic vulnerability assessment (SVA) of urban residential buildings

© 2018 by the authors. Earthquakes are among the most catastrophic natural geo-hazards worldwide and endanger numerous lives annually. Therefore, it is vital to evaluate seismic vulnerability beforehand to decrease future fatalities. The aim of this research is to assess the seismic vulnerability of residential houses in an urban region on the basis of the Multi-Criteria Decision Making (MCDM) model, including the analytic hierarchy process (AHP) and geographical information system (GIS). Tabriz city located adjacent to the North Tabriz Fault (NTF) in North-West Iran was selected as a case study. The NTF is one of the major seismogenic faults in the north-western part of Iran. First, several parameters such as distance to fault, percent of slope, and geology layers were used to develop a geotechnical map. In addition, the structural construction materials, building materials, size of building blocks, quality of buildings and buildings-floors were used as key factors impacting on the building’s structural vulnerability in residential areas. Subsequently, the AHP technique was adopted to measure the priority ranking, criteria weight (layers), and alternatives (classes) of every criterion through pair-wise comparison at all levels. Lastly, the layers of geotechnical and spatial structures were superimposed to design the seismic vulnerability map of buildings in the residential area of Tabriz city. The results showed that South and Southeast areas of Tabriz city exhibit low to moderate vulnerability, while some regions of the north-eastern area are under severe vulnerability conditions. In conclusion, the suggested approach offers a practical and effective evaluation of Seismic Vulnerability Assessment (SVA) and provides valuable information that could assist urban planners during mitigation and preparatory phases of less examined areas in many other regions around the world

Efficacious, effective, and embedded interventions: Implementation research in infectious disease control

Background: Research in infectious disease control is heavily skewed towards high end technology; development of new drugs, vaccines and clinical interventions. Oft ignored, is the evidence to inform the best strategies that ensure the embedding of interventions into health systems and amongst populations. In this paper we undertake an analysis of the challenge in the development of research for the sustainable implementation of disease control interventions. Results: We highlight the fundamental differences between the research paradigms associated with the development of technologies and interventions for disease control on the one hand and the research paradigms required for enhancing the sustainable uptake of those very same interventions within the communities on the other. We provide a definition for implementation research in an attempt to underscore its critical role and explore the multidisciplinary science needed to address the challenges in disease control. Conclusion: The greatest value for money in health research lies in the sustainable and effective implementation of already proven, efficacious solutions. The development of implementation research that can help provide some solutions on how this can be achieved is sorely needed

Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells

Background: The plasma cholesterol and triacylglycerol lowering effects of Tamarindus indica extract have been previously described. We have also shown that the methanol extract of T. indica fruit pulp altered the expression of lipid-associated genes including ABCG5 and APOAI in HepG2 cells. In the present study, effects of the same extract on the release of proteins from the cells were investigated using the proteomics approach. Methodology/Principal Findings: When culture media of HepG2 cells grown in the absence and presence of the methanol extract of T. indica fruit pulp were subjected to 2-dimensional gel electrophoresis, the expression of seven proteins was found to be significantly different (p<0.03125). Five of the spots were subsequently identified as alpha enolase (ENO1), transthyretin (TTR), apolipoprotein A-I (ApoA-I; two isoforms), and rab GDP dissociation inhibitor beta (GDI-2). A functional network of lipid metabolism, molecular transport and small molecule biochemistry that interconnects the three latter proteins with the interactomes was identified using the Ingenuity Pathways Analysis software. Conclusion/Significance: The methanol extract of T. indica fruit pulp altered the release of ENO1, ApoA-I, TTR and GDI-2 from HepG2 cells. Our results provide support on the effect of T. indica extract on cellular lipid metabolism, particularly that of cholesterol

Visualizing spatially correlated dynamics that directs RNA conformational transitions

RNAs fold into three- dimensional ( 3D) structures that subsequently undergo large, functionally important, conformational transitions in response to a variety of cellular signals(1-3). RNA structures are believed to encode spatially tuned flexibility that can direct transitions along specific conformational pathways(4,5). However, this hypothesis has proved difficult to examine directly because atomic movements in complex biomolecules cannot be visualized in 3D by using current experimental methods. Here we report the successful implementation of a strategy using NMR that has allowed us to visualize, with complete 3D rotational sensitivity, the dynamics between two RNA helices that are linked by a functionally important trinucleotide bulge over timescales extending up to milliseconds. The key to our approach is to anchor NMR frames of reference onto each helix and thereby directly measure their dynamics, one relative to the other, using 'relativistic' sets of residual dipolar couplings ( RDCs)(6,7). Using this approach, we uncovered super- large amplitude helix motions that trace out a surprisingly structured and spatially correlated 3D dynamic trajectory. The two helices twist around their individual axes by approximately 536 and 1106 in a highly correlated manner ( R = 0.97) while simultaneously ( R = 0.81 - 0.92) bending by about 94 degrees. Remarkably, the 3D dynamic trajectory is dotted at various positions by seven distinct ligand- bound conformations of the RNA. Thus even partly unstructured RNAs can undergo structured dynamics that directs ligand- induced transitions along specific predefined conformational pathways.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62506/1/nature06389.pd

Nanomechanics of individual aerographite tetrapods

R.A., O.L. and K.S. would like to thank the German Research Foundation (DFG) for the financial support under schemes AD 183/17-1 and SFB 986-TP-B1, respectively, and the Graphene FET Flagship. R.M. and D.E. would like to thank for financial support from Latvian Council of Science, no. 549/2012. N.M.P. is supported by the European Research Council (ERC PoC 2015 SILKENE no. 693670) and by the European Commission H2020 under the Graphene Flagship (WP14 ‘Polymer Composites’, no. 696656) and under the FET Proactive (‘Neurofibres’ no. 732344). S.S. acknowledges support from SILKENE

Pliocene-Quaternary crustal melting in central and northern Tibet and insights into crustal flow

There is considerable controversy over the nature of geophysically recognized low-velocity-high-conductivity zones (LV-HCZs) within the Tibetan crust, and their role in models for the development of the Tibetan Plateau. Here we report petrological and geochemical data on magmas erupted 4.7-0.3 Myr ago in central and northern Tibet, demonstrating that they were generated by partial melting of crustal rocks at temperatures of 700-1,050°C and pressures of 0.5-1.5 GPa. Thus Pliocene-Quaternary melting of crustal rocks occurred at depths of 15-50 km in areas where the LV-HCZs have been recognized. This provides new petrological evidence that the LV-HCZs are sources of partial melt. It is inferred that crustal melting played a key role in triggering crustal weakening and outward crustal flow in the expansion of the Tibetan Plateau