945 research outputs found
Epidemiological evaluation of cat health at a first-response animal shelter in Fukushima, following the Great East Japan Earthquakes of 2011.
The Great East Japan Earthquakes of March 11, 2011 caused immense harm to the community and subsequent nuclear accident in Fukushima Prefecture extended the damage. Local residents were forced to evacuated without pets and the left behind animals were rescued from the restricted zone one month later. Unplanned animal rescue and unregulated sheltering caused secondary damage to animals such as disease epidemics at impounded animal shelter. The purpose of this study was to retrospectively evaluate the incidence of upper respiratory infection (URI) and diarrhea in cats at the first response animal shelter in Fukushima, and investigate factors affecting the duration of disease and determinants of treatments performed. Eighty percent and 59% of impounded cats developed URI, 71% and 54% of cats developed diarrhea, and 91% and 83% of cats had at least one disease in 2011 and 2012, respectively. Uses of multiple drug administration (more than five drugs) was associated with prolonged URI and diarrhea. Multiple antibiotics, antihistamines, interferon, and steroids were associated with relapse of and prolonged URI. Developing a standardized treatment protocol for commonly observed diseases at Japanese animal shelters to prevent and control diseases, to promote animal welfare, and protect public health in the face of future disasters is overdue
Educational Probe for Developing Online Education: A Case of Online Problem-Based Learning in Design Education in India
The COVID-19 pandemic brought challenges and opportunities for higher education and one of the important areas was online education. Especially in design field, Online Problem-Based Learning has emerged as a promising method. This paper explores the potential of online-PBL and how it can be developed through a prototype approach. An action research in Indian HEI shows insights regarding the potentiality of online-PBL and application of a prototype approach to educational development activities. A concept of educational probes was proposed as a method to design educational program. © The Author(s), 2022
Magnetotransport in Sr3PbO antiperovskite with three-dimensional massive Dirac electrons
Novel topological phenomena are anticipated for three-dimensional (3D) Dirac
electrons. The magnetotransport properties of cubic
antiperovskite, theoretically proposed to be a 3D massive Dirac electron
system, are studied. The measurements of Shubnikov-de Haas oscillations and
Hall resistivity indicate the presence of a low density ( ) of holes with an extremely small cyclotron mass of
0.01-0.06. The magnetoresistance is linear in
magnetic field with the magnitude independent of temperature. These results
are fully consistent with the presence of 3D massive Dirac electrons in . The chemical flexibility of the antiperovskites and our findings
in the family member, , point to their potential as a model
system in which to explore exotic topological phases
Preparaciones de base líquida vs. citología convencional: adecuación de las muestras y coincidencia de diagnóstico en lesiones orales
Objetivo: Comparar la efectividad de la muestra y la coincidencia
de diagnostico entre preparaciones de base liquida y
frotis convencionales en lesiones orales, y probar la viabilidad
de la prueba inmuno-citoquimica en preparaciones de base
liquida de lesiones de carcinoma oral. Material y Metodos: Se
obtuvieron muestras de 44 pacientes. Primeramente se prepararon
frotis convencionales, usando un dispositivo cytobrush.
A continuacion se sumergio el cepillo que contenia el material
residual en un liquido conservante. La muestra en el mismo
fue procesada de acuerdo con las indicaciones del fabricante
(AutoCyte, Inc. Elon College, North Carolina, USA). Se
tineron preparaciones de ambas tecnicas de acuerdo con el
metodo de Papanicolaou. Para la prueba inmuno-citoquimica
se usaron conjuntamente AE1/AE3 (Dako, CA, USA) para
las lesiones de carcinoma oral, de acuerdo con el metodo de
la Estreptovidina-biotina-peroxidasa. Se uso la prueba exacta
de Fisher; fijandose la probabilidad significativa en p . 0.05.
Resultados: Ambas tecnicas coincidieron en el diagnostico
citologico en todos los casos donde se uso una muestra adecuada;
en 3 casos el frotis convencional mostro hipocelularidad y, por
lo tanto, resulto inadecuado para el analisis. En el analisis
de muestras, la citologia de base liquida mostro una mejora
general estadisticamente significativa), de un 41% en espesura
de frotis y de un 66% en la distribucion de celulas (p . 0.05),
ademas de una reduccion en la superposicion de celulas y la
presencia de sangre (p . 0.05). La morfologia celular se observó mejor en las preparaciones de base líquida. Las reacciones de la
prueba inmuno-citoquímica fueron positivas en todos los casos
de malignidad, siendo especialmente clara la observación de
células inmuno-marcadas. Conclusión: Tanto las preparaciones
de base líquida como los frotis convencionales son dignos de
confianza desde el punto de vista del diagnóstico; el método de
base líquida mostró una mejora general en la preservación de
muestras, adecuación de ejemplares, observación de morfología
celular y reproducibilidad.Objective: To compare specimen adequacy and diagnostic
agreement between liquid-based preparations and conventional
smears in oral lesions, and to test the viability of immunocytochemical
assay in liquid-based preparations from oral carcinoma
lesions. Material and Methods: Samples were collected from
44 patients. Conventional smears were prepared first, using a
cytobrush device. Then the brush, containing the residual material,
was immersed in a preservative fluid. The sample in the
preservative fluid was processed according to the manufacturer
directions (AutoCyte, Inc. Elon College, North Carolina, USA).
Slides of both techniques were stained by Papanicolaou method.
For immunocytochemical assay, a cytokeratin pool AE1/AE3
(Dako, CA, USA) was applied in liquid-based preparations
from oral carcinoma lesions following the Streptavidin-biotinperoxidase
method. Fisher's exact test was used; significance
was set for p = 0.05.
Results: Both techniques agreed on cytologic diagnosis in every
case they yielded an adequate specimen; in 3 cases conventional
smear resulted in hypocellularity and therefore inadequate for
analysis. On specimen analysis, the liquid-based cytology demonstrated
a statistically significant, 41% overall improvement
in smear thickness and 66% in cell distribution (p = 0.05), and a
reduction in cell overlapping and presence of blood (p = 0.05).
The cell morphology was better visualized in the liquid-based
preparations. The immunocytochemical assay reactions were
positive in all malignant cases, the visualization of the immu-nostained cells being especially clear.
Conclusion: Both, the liquid-based preparation and conventional
smear, are diagnostically reliable; the liquid-based method
showed an overall improvement on sample preservation, specimen
adequacy, visualization of cell morphology and reproducibility
Prospects for improving the sensitivity of KAGRA gravitational wave detector
KAGRA is a new gravitational wave detector which aims to begin joint observation with Advanced LIGO and Advanced Virgo from late 2019. Here, we present KAGRA's possible upgrade plans to improve the sensitivity in the decade ahead. Unlike other state-of-the-art detectors, KAGRA requires different investigations for the upgrade since it is the only detector which employs cryogenic cooling of the test mass mirrors. In this paper, investigations on the upgrade plans which can be realized by changing the input laser power, increasing the mirror mass, and injecting frequency dependent squeezed vacuum are presented. We show how each upgrade affects to the detector frequency bands and also discuss impacts on gravitational-wave science. We then propose an effective progression of upgrades based on technical feasibility and scientific scenarios
Effect of Pets on Human Behavior and Stress in Disaster
Animal-related consequences were not anticipated in disaster preparedness planning in Japan at the time of its massive earthquakes in 2011. Evacuation failure was quite common due to pet ownership in this disaster. Public attention to the welfare of affected animals in this disaster triggered an awareness of the importance of caring for their needs. However, research on human behavior toward pets or effect of pets on human during disasters remains sparse. In this study, post-traumatic stress disorder (PTSD) scores among pet-owners and non-pet owners in Japan's 2011 earthquake disaster were compared, and attitudes toward pets were evaluated. A questionnaire was distributed to attendees, and interviews were performed at an annual animal welfare event. The Japanese-language version of the revised Impact of Event Scale was used to evaluate PTSD from the disaster. PTSD scores were higher in pet-owners compared to non-pet owners immediately after the earthquakes, but were lower in pet-owners compared to non-pet owners 4.4 years following the disaster. Most people opined that pets should evacuate with people, although less than half of non-pet owners agreed with having animals co-located at evacuation centers. In order to enhance safety and security of both humans and animals at evacuation centers, it is important to proactively address animal issues in disaster preparedness planning. Although pets were regarded by some as adverse risk factors for human health and safety during a disaster; this study instead suggests that pets may play an important positive and protective role for disaster victims
Inverse-perovskites A3BO (A = Sr, Ca, Eu/B = Pb, Sn) : a platform for control of Dirac and Weyl fermions
This work was partly supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (Grant Nos. 24224010, 15K13523, JP15H05852, JP15K21717, and 17H01140), EPSRC (Grant No. EP/P024564/1), and the Alexander von Humboldt FoundationBulk Dirac electron systems have attracted strong interest for their unique magnetoelectric properties as well as their close relation to topological (crystalline) insulators. Recently, the focus has been shifting toward the role of magnetism in stabilizing Weyl fermions as well as chiral surface states in such materials. While a number of nonmagnetic systems are well known, experimental realizations of magnetic analogs are a key focus of current studies. Here, we report on the physical properties of a large family of inverse perovskites A3BO (A = Sr, Ca, Eu/B = Pb, Sn) in which we are able to not only stabilize 3D Dirac electrons at the Fermi energy but also chemically control their properties. In particular, it is possible to introduce a controllable Dirac gap, change the Fermi velocity, tune the anisotropy of the Dirac dispersion, and—crucially—introduce complex magnetism into the system. This family of compounds therefore opens up unique possibilities for the chemical control and systematic investigation of the fascinating properties of such topological semimetals.Publisher PDFPeer reviewe
Search for gravitational waves from low mass compact binary coalescence in 186 days of LIGO’s fifth science run
We report on a search for gravitational waves from coalescing compact binaries, of total mass between 2 and 35M⊙, using LIGO observations between November 14, 2006 and May 18, 2007. No gravitational-wave signals were detected. We report upper limits on the rate of compact binary coalescence as a function of total mass. The LIGO cumulative 90%-confidence rate upper limits of the binary coalescence of neutron stars, black holes and black hole-neutron star systems are 1.4×10−2, 7.3×10−4 and 3.6×10−3 yr−1 L−110, respectively, where L10 is 1010 times the blue solar luminosity
Search for gravitational waves from low mass binary coalescences in the first year of LIGO’s S5 data
We have searched for gravitational waves from coalescing low mass compact binary systems with a total mass between 2M⊙ and 35M⊙ and a minimum component mass of 1M⊙ using data from the first year of the fifth science run of the three LIGO detectors, operating at design sensitivity. Depending on the mass, we are sensitive to coalescences as far as 150 Mpc from the Earth. No gravitational-wave signals were observed above the expected background. Assuming a population of compact binary objects with a Gaussian mass distribution representing binary neutron star systems, black hole–neutron star binary systems, and binary black hole systems, we calculate the 90% confidence upper limit on the rate of coalescences to be 3.9×10−2 yr−1L−110, 1.1×10−2 yr−1L−110, and 2.5×10−3 yr−1L−110, respectively, where L10 is 1010 times the blue solar luminosity. We also set improved upper limits on the rate of compact binary coalescences per unit blue-light luminosity, as a function of mass
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