A Multiple Case Study of Co-Teachers’ Technology Integration Knowledge: How It Is Held, Built, and Shared

This multiple case study explored how secondary-level co-teachers hold, build, and share knowledge related to technology integration. Co-teaching, a special education service delivery model, involves a general and special educator who share responsibility for planning, delivering, and assessing instruction (Friend, 2014). Through the lens of the Technological Pedagogical Content Knowledge (TPACK) framework (Mishra & Koehler, 2006), I explored the perspectives and experiences of four co-teaching pairs who regularly integrated technology into instruction. Study results suggested that these teachers held knowledge, beliefs, and values that influenced their classroom practices. The micro-level contextual elements in the teachers’ workplaces, along with meso-levels supports, influenced how the teachers built and shared knowledge with and from each other. their collaborative relationships, which were based upon parity, respect, and communication, supported a professional work environment of sharing and learning. as these teachers engaged in dialogue within their teaching and learning partnerships, individually-held knowledge (TPACK) was distributed between the co-teachers. Content-, grade-, and school-level collaborations addressing technology integration also resulted in the distribution of TPACK school-wide. Implications of these results include recommendations for how school leaders may support effective co-teaching, which can enhance teachers’ professional learning related to technology integration and encourage the development of distributed knowledge

Traditional Nonsteroidal Anti-Inflammatory Drugs and Postmenopausal Hormone Therapy: A Drug–Drug Interaction?

It is controversial whether estrogens confer cardioprotection. This study suggests that even should such a benefit exist, COX inhibitors may undermine cardioprotective effects of hormone therapy

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden

The global context: sustainable development goals and gender equality

The 2030 Development Agenda, adopted unanimously by the 193 United Nations (UN) member countries on September 25, 2015, is a universal call to action for transforming the world to one that is free from poverty, inequality, violence, manmade natural disasters, and resource depletion for the current and future generations. The 2030 Agenda sets 17 Sustainable Development Goals (SDGs) and 169 associated Targets that represent a broad intergovernmental consensus on the world’s development priorities. The Goals were set through a participative process led by the UN, which included states, companies, civil society organizations, scientists, and experts over a period of 3 years. “Commitment to universal human rights” is depicted as the overarching normative and ethical framework for the SDGs