1,518 research outputs found

    Your Vitamin C Strategy

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    Research has proven that vitamin C in the diet is essential to good health. Here\u27s what you can do in selecting and preparign foods to insure an adequate amount of this important ascorbic acid in your family meals

    Spiritual and existential meanings of death and dying : a palliative nursing care perspective.

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    This study aimed to explore the ways palliative care nurses conceptualised the death and dying experiences of their patients. Spiritual and existential meaning-making was a particular focus, as well as the ways in which these intersected with Elisabeth Kübler-Ross’s (1969) five stages of dying. Ten palliative care nurses at a hospice facility in Johannesburg participated in the study. They were interviewed from 1 July to 20 August 2009. A semi-structured interview format was used. A thematic content analysis was used to analyse the data, with two broad themes emerging: experiences of death and dying, and meaning-making. Within the first theme, it was found that the five stages of dying, although identifiable, are found to be vacillating, and often occur simultaneously. The patients’ experiences themselves were perceived by nurses to be more complex and nuanced than the theory suggested, and some experiences did not conform to the stage model at all. Meaning-making was witnessed to occur regardless of patients’ level and type of religiosity. Existential meaning could be found through religion or without it. However, religion also served as a way to explain death, and when this failed, it could result in distress. The ways in which patients made meaning often directly influenced their emotional experiences, and thus intersections were common

    Help Wanted: Seven Year Old Boy Fears Failure In Reading; Won\u27t Try. Apply: Anywhere School

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    Genetic and Molecular Analysis of dec-11 in C. elegans\u27 Intestinal Pacemaker Activity

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    Rhythmic behaviors are ubiquitous phenomena in plant and animal phyla. Ultradian rhythmic behaviors occur with a period of less than 24 hours and include such rhythmic behaviors as the beating of the heart and peristalsis in the gut. The nematode C. elegans exhibits three well-characterized ultradian rhythmic behaviors: ovulation, pharyngeal pumping, and the defecation motor program (DMP). The DMP occurs every ~45 seconds in wild-type worms and comprises three distinct muscle contractions: a posterior body contraction (pBoc), an anterior body contraction (aBoc), and an enteric muscle contraction (Emc), which is coupled to expulsion (Exp). The rhythmicity of the DMP is Ca2+-dependent, meaning fluctuations in intracellular Ca2+ levels in the pacemaker cell regulate the behavior. A forward genetic screen was performed to identify genes necessary for proper pacemaker function (Iwasaki et al., 1995). One of the mutants isolated, dec-11, lacks pacemaker activity and displays long and irregular defecation cycles. However, the gene mutated in dec-11 worms has not been identified. In order to determine the function of the dec-11 gene in the control of pacemaker activity for the DMP, genetic analysis and video microscopy were utilized. First, genetic analysis was performed to test whether dec-11 acts upstream of IP3 mediated Ca2+ release using mutations in ipp-5 and lfe-2, which encode an IP3 phosphatase and an IP3 kinase respectively. dec-11;ipp-5 and dec-11;lfe-2 double mutants both showed partial suppression of the irregular defecation cycle phenotype characteristic of dec-11 single mutants. Additionally, when dec-11 worms were grown on high Mg2+ plates, the irregular defecation cycles were suppressed, suggesting a role for dec-11 in the regulation of the DMP. Parallel work using SNP interval mapping and whole-genome sequencing has allowed us to identify a molecular interval in which dec-11 is located and to generate a list of candidate genes. Additionally, RNAi analysis of candidate genes will allow us to determine the molecular identity of dec-11. Taken together these data are consistent with a model that places the function of dec-11 in the regulation of the initiating event of the DMP

    Compositions And Methods Relating To Control DNA Construct

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    The invention relates to novel control DNA constructs, and methods and kits for using and making the same, which provide comprehensive controls useful for quality assurance in the diagnostic detection of complex genetic diseases such as, but not limited to, cystic fibrosis, and for quality assurance in nucleic acid assays to detect components associated with an environmental condition or a biological organism

    The World Bank and Its Critics: the Case of Sub-Saharan Africa

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    In 1981, as Sub-Saharan Africa continued in its downward spiral of economic demise, the World Bank issued a major study on the causes of Africa's economic woes and potential short-term steps to alleviate them. The World Bank's Accelerated Development in Sub-Saharan Africa: An Agenda for Action. In this paper, the authors dissect a number of the major controversies engendered by the World Bank Report, by presenting and evaluating the differences between the authors of the Report and critics of the Report.Center for Research on Economic Development, University of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/100718/1/ECON187.pd

    Sperm and northern bottlenose whale interactions with deep-water trawlers in the western North Atlantic

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    An emerging explorer grant from National Geographic (#4711-6) and funding from Fisheries and Oceans Canada supported fieldwork conducted by LF in the study area between 2015-2017.Commercial fisheries have increased in all the world’s oceans with diverse unintended impacts on marine ecosystems. As a result of resource overlap, interactions between cetaceans and fisheries are a common occurrence and, in many cases, can give rise to significant conservation issues. Research on the distribution and types of such interactions is important for efficient management. In this study, we describe the behaviors of two whale species: sperm whales (Physeter macrocephalus) and northern bottlenose whales (Hyperoodon ampullatus), interacting with benthic trawlers fishing off the eastern Grand Banks of the western North Atlantic in 2007. Whale interactions were only observed when vessels were targeting Greenland halibut (Reinhardtius hippoglossoides) in deep-water fishing areas and were most common during net hauling. Sperm whales and northern bottlenose whales appeared to engage in feeding behavior close to the surface during hauling, especially during the latter stages, suggesting they targeted fish escapees rather than discards. Using photo-identification methods, seven individual sperm whales were identified with multiple resights of six individuals being recorded over an almost two month period. The maximum distance between two resights was 234 km, suggesting individual sperm whales were repeatedly targeting and even following fishing vessels over multiple days and between fishing areas. By contrast, there were no photographic resights of individual northern bottlenose whales within this study, or with substantial photo-identification catalogues from other adjacent high density areas, suggesting that individuals of this species may be less likely to follow vessels or move between areas. This study documents the earliest confirmed records of northern bottlenose whales in this remote region. These interactions and high encounter rates may indicate that adjacent populations are recovering from the previous century of commercial whaling. Our study provides new insights and details on whale-fisheries interactions, which can inform future research and help managers understand the real and perceived impacts of depredation behaviour on fisheries and whales.Publisher PDFPeer reviewe

    Deformations of reducible representations of 3-manifold groups into PSL_2(C)

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    Let M a 3-manifold with torus boundary which is a rational homology circle. We study deformations of reducible representations of p_1(M) into PSL_2(C) associated to a simple zero of the twisted Alexander polynomial. We also describe the local structure of the representation and character varieties.Comment: Published by Algebraic and Geometric Topology at http://www.maths.warwick.ac.uk/agt/AGTVol5/agt-5-40.abs.htm
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