ИНФОРМАЦИОННЫЕ ОСНОВЫ КУРСА «ОРГАНИЗАЦИОННОЕ ПРОЕКТИРОВАНИЕ» ДЛЯ СТУДЕНТОВ, ОБУЧАЮЩИХСЯ ПО СПЕЦИАЛЬНОСТИ 032001 - ДОКУМЕТОВЕДЕНИЕ ИДОКУМЕНТАЦИОННОЕОБЕСПЕЧЕНИЕУПРАВЛЕНИЯ

The information basics of the course «Organizational planning» are describes inthe article on the basis of three clusters of information training: basic, professional andtechnological. The experimental study has shown high efficiency in Tula State Lev Tolstoy Pedagogical University of the proposedmethodological technique.В статье рассмотрены информационные основыучебногокурса«Организационное проектирование» на базе трех кластеров информационной подготовки: базового, профессионального и технологического. ЭкспериментальноеисследованиевТульском государственном педагогическом университете им. Л.Н. Толстого показало высокую эффективность предложенного методического приема

A nearly complete database on the records and ecology of the rarest boreal tiger moth from 1840s to 2020

Global environmental changes may cause dramatic insect declines but over century-long time series of certain species’ records are rarely available for scientific research. The Menetries’ Tiger Moth (Arctia menetriesii) appears to be the most enigmatic example among boreal insects. Although it occurs throughout the entire Eurasian taiga biome, it is so rare that less than 100 specimens were recorded since its original description in 1846. Here, we present the database, which contains nearly all available information on the species’ records collected from 1840s to 2020. The data on A. menetriesii records (N = 78) through geographic regions, environments, and different timeframes are compiled and unified. The database may serve as the basis for a wide array of future research such as the distribution modeling and predictions of range shifts under climate changes. It represents a unique example of a more than century-long dataset of distributional, ecological, and phenological data designed for an exceptionally rare but widespread boreal insect, which primarily occurs in hard-to-reach, uninhabited areas of Eurasia.Peer reviewe

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

Mineralogy of Particulate Suspended Matter of the Severnaya Dvina River (White Sea, Russia)

This paper seeks to generalize the data obtained over 4 years of investigation of the suspended sediment mineral composition in Severnaya Dvina River. The sampling of the river water to isolate suspended particulate matter (SPM) using the method of sedimentation from large water volumes (200&ndash;800 L) was carried out at two points of the delta with different hydrological regimes every month for four years. SPM samples weighing 1 g and more allowed us to obtain and preserve for different analytical procedures the grain size fractions from 1.0&ndash;0.5 to &lt;0.001 mm (from sands to pelit). The analyses of fractions revealed a sharp prevalence of pelitic fractions (&lt;0.01 mm) (near 90% on average), while the share of silt was 4%&ndash;5%. Coarse fractions were found in the SPM of the main stream of the river but were absent in the samples taken at the point near the river&ndash;sea boundary. The determinations of clastic, clay, and some other minerals using the method of X-ray diffraction analysis have shown that in the group of clastic minerals, quartz and plagioclase prevail. Among the clay minerals, smectite and illite were present in high quantities, and chlorite and kaolinite were in lower quantitative. The distribution of minerals in the grain size fractions showed that the sum of clastic minerals reached its highest content of up to 84% in silt fractions (0.05&ndash;0.01 mm), while the sum of clay minerals in this fraction was minimal (about 15%). Investigations of seasonal variations of clastic and clay minerals during the whole period showed that the contents of minerals in the SPM of the Severnaya Dvina did not change much over the year. As a result of this work, the following trend was established on the behavior of all kinds of minerals: during the periods of high water in spring and autumn, a slightly increased quantity of clastic minerals was detected in comparison to winter and summer, while the variations in the quantities of clay minerals were insignificant

INFORMATION BASES OF THE COURSE «ORGANIZATIONAL PLANNING» FOR STUDENTS OF THE SPECIALITY 032001 «DOCUMENTATION MANAGEMENT AND ADMINISTRATIVE DOCUMENTATION SUPPORT »

The information basics of the course «Organizational planning» are describes inthe article on the basis of three clusters of information training: basic, professional andtechnological. The experimental study has shown high efficiency in Tula State Lev Tolstoy Pedagogical University of the proposedmethodological technique

Chemical composition and fluxes of deep sea suspended matter within and over the 9°50'N hydrothermal field, EPR

Results of geochemical studies of suspended matter from the water mass over the hydrothermal field at 9°50'N on the East Pacific Rise are reported. The suspended matter was sampled in background waters, in the buoyant plume, and in the near-bottom waters. Contents of Si, Al, P, Corg, Fe, Mn, Cu, Zn, Ni, Co, As, Cr, Cd, Pb, Ag, and Hg were determined. No definite correlations were found between the elements in the background waters. Many of the chemical elements correlated with Fe and associated with its oxyhydroxides in the buoyant plume. In the near-bottom waters trace elements are associated with Fe, Zn, and Cu (probably, with their sulfides formed during mixing of hydrothermal fluids with seawater). Chemical composition of sediment matter precipitated in a sediment trap was similar to the near-bottom suspended matter