ERCP and splenic injury

Abstractendoscopic Retrograde Colangiopancreatography (eRCP) is an invasive procedure with important complications that occurs in 5%-10% of the cases. The most frequent procedure related complications are: acute pancreatitis, hemorrhage, perforation and infection. an infrequent but potentially life threatening eRCP complication is the splenic injury, with very few cases reported in the literature. We report a patient with cholecholithiasis and biliary pancreatitis who was diagnosed with a subcapsular splenic laceration a few hours after an eRCP. Clinicians should be alerted to this potential post-procedure complication associated with eRCP

Microstructural evolution and mechanical behavior of an Al-6061 alloy processed by repetitive corrugation and straightening

The repetitive corrugation and straightening process is a severe plastic deformation technique that is particularly suited to process metallic sheets. With this technique, it is possible to develop nano/ultrafine-grained structured materials, and therefore, to improve some mechanical properties such as the yield strength, ultimate tensile strength, and fatigue lifetime. In this study, an Al-6061 alloy was subjected to the repetitive corrugation and straightening process. A new corrugation die design was proposed in order to promote a heterogeneous deformation into the metallic sheet. The evolution of the mechanical properties and microstructure obtained by electron backscatter diffraction of the alloy showed a heterogeneous distribution in the grain size at the initial cycles of the repetitive corrugation and straightening process. Uniaxial tensile tests showed a significant increase in yield strength as the number of repetitive corrugation and straightening passes increased. The distribution of the plastic deformation was correlated with the hardness distribution on the surface. The hardness distribution map matched well with the heterogeneous distribution of the plastic deformation obtained by finite element simulation. A maximum average hardness (147 HV) and yield strength (385 MPa) was obtained for two repetitive corrugation and straightening cycles samplePeer ReviewedPostprint (published version

Preliminary study of the enzyme ubiquitin carboxylterminal hydrolase 14 (UBP6) in Giardia intestinalis: structural bioinformatic analysis and transcriptional profile during encystation

This paper presents a combined approachwith two aims. The first is to analyze thereported sequence of the enzyme ubiquitincarboxyl-terminal hydrolase 14 of Giardiaintestinalis (UBP6) through computationalmethods to find components related withits hypothetical function. The second isto determine if the protein-coding gene isexpressed in G. intestinalis and, if such isthe case, also determine its transcriptionpattern along the life cycle of the parasite. Itwas established that the protein belongs tothe family of Cys-dependent deubiquitinasesand more specifically to ubiquitin specificproteases (USPs). Moreover, the catalyticcenter with the complete triad as well astypical features of the USP motif were alsoidentified. Since the computational findingssuggest that the enzyme could be functional,reverse transcription coupled to PCR wasused as a first approach to establish if in factthe coding gene is expressed in the parasite.Interestingly, it was found not only thatthe gene is expressed, but also that thereis a transcription variation along the lifecycle of the parasite. These two findings arethe starting point for further studies sincethey tentatively suggest that this enzymecould be involved in the protein turnoverthat occurs during parasite encystation.Although preliminary, this study is the firstreport concerning the study of a specificdeubiquitinating enzyme in the parasite G.intestinalis

Situational analysis of the subjective well-being of university software developers in Puebla

Integral well-being is vital for the optimal functioning of people. The requirements for a software developer in the performance of their professional activity are varied and complex. These requirements range from working in multidisciplinary and multilingual teams, going through the challenge of technological advances of the discipline to commit to quality and innovation. To face these demands, it is essential that the developers have an optimal functioning, where the experience emotional and satisfaction with life play an important role. The objective of this article is to analyze the subjective well-being of university software developers in Puebla. The research is a quantitative cross-correlation study to identify statistically significant relationships between the different welfare variables. The study involved 47 university software developers from the city of Puebla. We use Pearson's multivariate correlation to validate the instruments and find relationships between variables, and Chi-squared statistics to calculate the dependency between them. The results reveal that the university software developers experience with higher incidence and intensity, the positive affections over the negatives. The affective balance (Net Affect), calculated as the difference of the weighted averages by duration between positive affective states and negative, was positive (mean = 1.31). "Concentrated" is the positive affective state with the highest incidence and with the highest reported intensity. "Tired" is the most experienced negative affect and highest in intensity. Developers spend 40% of their time experiencing negative affective states (U-index) and are moderately satisfied with their lives in general

Depression as a predictor of sleep quality in health workers who faced the COVID-19 pandemic in Mexico

Introduction: There is a relationship between depression and sleep quality; however, the impact of the COVID-19 pandemic on this association is unknown, especially for those health workers who faced the pandemic. Therefore, we aimed to identify the association between depression and sleep quality in health workers who faced the COVID-19 pandemic. Methods: A survey was performed on 150 health workers with at least 2 years of working tenure in a public maternal perinatal hospital in Mexico, between September and December 2021. Sociodemographic data, levels of sleep quality, depression, anxiety, and gastrointestinal function were obtained through a self-administered questionnaire. Cardiovascular risk was obtained according to age, lifestyle habits, blood pressure, anthropometry, body composition and biochemical measurements. Results: Those with depression were 10.3 times more likely to have poor sleep quality compared to those without depression, adjusted for gastrointestinal function (95% CI 2.92 – 36.54, p<0.001). Those with depression were 7.23 times more likely to have poor sleep quality compared to those without depression, adjusted for gastrointestinal function, anxiety, and cardiovascular risk (95% CI 1.85-28.14, p<0.001). Conclusion: Health workers’ depression should be considered a predictor of poor sleep quality, especially in those who faced the COVID-19 pandemic

Influencia Del Comité De Auditoría En El Desempeño Financiero Organizacional, En Empresas Mexicanas Cotizadas (2010-2014)

The purpose of this paper is to know the level of compliance with corporate practices related to the audit function, contained in the Code of Best Corporate Practices, issued by the National Banking and Securities Commission and influence on organizational financial performance (specifically on financial profitability), for this, a sample of 405 questionnaires of best corporate practices, belonging to 125 non-financial companies, are listed on the Mexican Stock Exchange during the period, 2010-2014. The results of the application of the linear regression model, could allow us to affirm that the Audit Function (INDEX_FA), increases the financial profitability of the organizations, which is a great success on the part of the Mexican regulators

Factores de prevalencia de mastitis subclínica en vacas lecheras del distrito de Florida, Región Amazonas, Perú

The aim of this study was to determine the main factors that influence the prevalence of subclinical mastitis in Florida, Amazonas Region, Peru. Fifty cows under hand-milking of 15 farms were used. The prevalence of subclinical mastitis was determined by the California Mastitis Test (CMT) and the DCC Test (DeLaval Direct Cell Counter). Milking routines were observed to determine the main prevalence factors. Data analysis was performed using contingency tables, the chi-square test and bivariate correlations. The prevalence of subclinical mastitis according to the DCC method was 52% and by CMT was 51%, without significant differences between methods. The main factors that influenced the prevalence of subclinical mastitis were due to poor hygiene practices and inadequate facilities.El objetivo de la investigación fue determinar los principales factores que influyen en la prevalencia de mastitis subclínica en la cuenca lechera de Florida, Región Amazonas, Perú. Se utilizaron 50 vacas de 15 fincas bajo ordeño manual. La prevalencia de mastitis subclínica se determinó mediante el California Mastitis Test (CMT) y el Test DCC (DeLaval Direct Cell Counter). Para determinar los principales factores de prevalencia se utilizó un formato de observación sobre rutinas de ordeño. El análisis de datos se realizó mediante tablas de contingencia, la prueba de chi-cuadrado y correlaciones bivariadas. Se encontró una prevalencia de mastitis subclínica, según el método DCC del 52% y mediante CMT del 51%, sin diferencias significativas entre métodos. Los principales factores que influyeron en la prevalencia de mastitis subclínica se debieron a deficientes prácticas de higiene e inadecuadas instalaciones

Padrão Tipo A de comportamento, estresse ocupacional e sintomas musculoesqueléticos em trabalhadores de colarinho branco

Musculoskeletal disorders have a multifactorial etiology, where not only physical factors, but also psychosocial ones in the workplace interact with the individual characteristics and psychological demands of employees, predisposing them to the development of such conditions. Because not all people will respond in the same way to the stressors that affect them, the relationship between the Type A behavior pattern, occupational stress and musculoskeletal symptoms was investigated. The study design was cross-correlational and the statistical analysis was carried out using Pearson's correlation (p < .05), Student's t test and multiple linear regression. 100 white-collar employees from the public sector from southern Puerto Rico participated, selected by availability. PCTA predominated, the anatomical regions with the highest symptomatic frequency were: neck, shoulders, upper and lower back; and the level of occupational stress reported was low average. A statistically significant relationship was found between PCTA, occupational stress and musculoskeletal symptoms; not so between occupational stress and symptoms. Differences were reported between employees with PCTA and PCTB and the results of the regression model indicate that the independent variables explain about 7% of the variability of symptoms. It is concluded that the sample of white-collar employees who exhibit PCTA have a higher incidence of suffering from pain, discomfort or numbness in the region of the neck and upper back and are more prone and susceptible to stress.Los desórdenes musculoesqueletales poseen una etiología multifactorial, donde no solo los factores físicos, sino también los psicosociales del área de trabajo interactúan con las características individuales y las demandas psicológicas de los empleados, predisponiéndolos al desarrollo de tales condiciones. Debido a que no todas las personas responderán de igual forma ante los estresores que le afectan, se investigó la relación entre el patrón de conducta Tipo A, el estrés ocupacional y los síntomas musculoesqueletales. El diseño del estudio fue transversal-correlacional y el análisis estadístico se llevó a cabo mediante correlación de Pearson (p < .05), prueba t de student y regresión lineal múltiple. Participaron 100 empleados de cuello blanco del sector público del sur de Puerto Rico, seleccionados por disponibilidad. Predominó el PCTA, las regiones anatómicas con mayor frecuencia sintomática fueron: cuello, hombros, espalda alta y baja; y el nivel de estrés ocupacional reportado fue promedio bajo. Se halló relación estadísticamente significativa entre el PCTA, el estrés ocupacional y los síntomas musculoesqueletales; no así entre el estrés ocupacional y los síntomas. Se reportaron diferencias entre los empleados con PCTA y PCTB y los resultados del modelo de regresión indican que las variables independientes explican cerca del 7 % de la variabilidad de los síntomas. Se concluye que la muestra de empleados de cuello blanco que exhiben PCTA, tienen mayor incidencia a padecer de dolor, molestia o entumecimiento en la región del cuello y espalda alta y son más propensos y susceptibles al estrés.Os distúrbios musculoesqueléticos têm etiologia multifatorial, onde não só os fatores físicos, mas também os psicossociais do ambiente de trabalho interagem com as características individuais e demandas psicológicas dos funcionários, predispondo-os ao desenvolvimento dessas condições. Como nem todas as pessoas responderão da mesma forma aos estressores que as afetam, a relação entre o padrão de comportamento do Tipo A, o estresse ocupacional e os sintomas musculoesqueléticos foi investigada. O desenho do estudo foi correlacional cruzado e a análise estatística foi realizada por meio de correlação de Pearson (p < .05), teste t de Student e regressão linear múltipla. Participaram 100 funcionários administrativos do setor público do sul de Porto Rico, selecionados de acordo com a disponibilidade. Predominou a PCTA, as regiões anatômicas com maior frequência sintomática foram: pescoço, ombros, parte superior e inferior das costas; e o nível de estresse ocupacional relatado foi de média baixa. Foi encontrada relação estatisticamente significativa entre PCTA, estresse ocupacional e sintomas musculoesqueléticos; não é assim entre estresse ocupacional e sintomas. Diferenças foram relatadas entre funcionários com PCTA e PCTB e os resultados do modelo de regressão indicam que as variáveis ​​independentes explicam cerca de 7% da variabilidade dos sintomas. Conclui-se que a amostra de funcionários de colarinho branco que apresentam PCTA tem maior incidência de dor, desconforto ou dormência na região do pescoço e parte superior das costas e são mais propensos e suscetíveis ao estresse

A beam-beam monitoring detector for the MPD experiment at NICA

The Multi-Purpose Detector (MPD) is to be installed at the Nuclotron Ion Collider fAcility (NICA) of the Joint Institute for Nuclear Research (JINR). Its main goal is to study the phase diagram of the strongly interacting matter produced in heavy-ion collisions. These studies, while providing insight into the physics of heavy-ion collisions, are relevant for improving our understanding of the evolution of the early Universe and the formation of neutron stars. In order to extend the MPD trigger capabilities, we propose to include a high granularity beam-beam monitoring detector (BE-BE) to provide a level-0 trigger signal with an expected time resolution of 30 ps. This new detector will improve the determination of the reaction plane by the MPD experiment, a key measurement for flow studies that provides physics insight into the early stages of the reaction. In this work, we use simulated Au+Au collisions at NICA energies to show the potential of such a detector to determine the event plane resolution, providing further redundancy to the detectors originally considered for this purpose namely, the Fast Forward Detector (FFD) and the Hadron Calorimeter (HCAL). We also show our results for the time resolution studies of two prototype cells carried out at the T10 beam line at the CERN PS complex.Comment: 16 pages, 12 figures. Updated to published version with added comments and correction