7 research outputs found

    Developing a generic approach to online automated analysis of writing and drawing tests in clinical patient profiling

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    Writing and drawing tests are widely used in the clinical environment for the diagnosis of a variety of neuropsychological conditions. Conventional assessment of these tests involves the inspection by trained assessors of the completed patient response. This article describes the development of a computer-based framework for data capture, automated feature analysis, and result reporting for a range of drawing- and writing-based test batteries. In developing this framework, we have exploited the commonality between tasks while allowing for both flexibility in configuration across condition-specific testing requirements and extensibility for future test development. Using the two example clinical conditions of visuospatial neglect and dyspraxia, we illustrate the advantages of utilizing a computer-based analysis system, describe a structured approach to system implementation, and demonstrate the generality of this implementation for different conditions of interest, which extends to feature selection and design

    HOT SUBTERRANEAN BIOSPHERE IN A CONTINENTAL OIL-RESERVOIR

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    THE presence of high concentrations of hyperthermophilic archaea in Alaskan oil fields has been attributed to viable hyperthermophiles in low concentrations in the injected sea water, but the existence of an indigenous community within the reservoir was ruled out(1). Here we present evidence for the existence of indigenous thermophilic bacteria and hyperthermophilic archaea from a continental petroleum reservoir about 1,670 m below the surface. The thermophilic isolates were repeatedly obtained from different wells and thrived in media similar to conditions in the wells, suggesting that these isolates are members of a deep indigenous thermophilic community. The unexpected presence of marine hyperthermophilic archaea in a deep continental environment extends the known ecological habitat of this group of organisms, and their unusual coexistence with terrestrial bacteria suggests that thermophiles may be widespread deep in the crust of the earth
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