Development of a model to predict the risk of early graft failure after adult-to-adult living donor liver transplantation

[Omissis

La Inserción Internacional de la Argentina de las últimas décadas: Un análisis comparativo de los principales lineamientos de la Política Exterior

El presente artículo se propone analizar 20 años de política exterior argentina través de un enfoque histórico-comparativo, indagando particularmente acerca de la existencia de elementos de cambio y continuidad. En ese sentido, se especificará un marco teórico estableciendo las variables a examinar, luego se identificarán y desarrollarán las características de los períodos históricos a comparar, 1989-2001 y 2002-2007, para finalmente señalar la existencia de semejanzas y/o diferencias en la estrategia de inserción internacional llevada a cabo por cada uno de los Gobiernos.This article proposes to analyze 20 years of Argentina's foreign policy through a comparative historical approach, inquiring particularly about the existence of elements of change and continuity. In this sense, it will be established a theoretical framework specifying the variables to consider, then will be identified and developed the characteristics of the historical periods to be compared, 1989-2001 and 2002-2007, to finally reveal the existence of similarities and / or differences in the international strategy carried out by each government.Fil: Giglio, Antonela. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas. Centro de Estudios Interdisciplinarios entre Problemas Internos y Locales; ArgentinaFil: Roark, Mariano Eduardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas. Centro de Estudios Interdisciplinarios entre Problemas Internos y Locales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentin

La Inserción Internacional de la Argentina de las últimas décadas: Un análisis comparativo de los principales lineamientos de la Política Exterior

El presente artículo se propone analizar 20 años de política exterior argentina través de un enfoque histórico-comparativo, indagando particularmente acerca de la existencia de elementos de cambio y continuidad. En ese sentido, se especificará un marco teórico estableciendo las variables a examinar, luego se identificarán y desarrollarán las características de los períodos históricos a comparar, 1989-2001 y 2002-2007, para finalmente señalar la existencia de semejanzas y/o diferencias en la estrategia de inserción internacional llevada a cabo por cada uno de los Gobiernos.This article proposes to analyze 20 years of Argentina's foreign policy through a comparative historical approach, inquiring particularly about the existence of elements of change and continuity. In this sense, it will be established a theoretical framework specifying the variables to consider, then will be identified and developed the characteristics of the historical periods to be compared, 1989-2001 and 2002-2007, to finally reveal the existence of similarities and / or differences in the international strategy carried out by each government.Fil: Giglio, Antonela. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas. Centro de Estudios Interdisciplinarios entre Problemas Internos y Locales; ArgentinaFil: Roark, Mariano Eduardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas. Centro de Estudios Interdisciplinarios entre Problemas Internos y Locales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentin

Post-operative morbidity following pancreatic duct occlusion without anastomosis after pancreaticoduodenectomy: a systematic review and meta-analysis

Background: Pancreatic duct occlusion (PDO) without anastomosis is a technique proposed to mitigate the clinical consequences of postoperative pancreatic fistulas (POPF) after pancreaticoduodenectomy. The aim of this study was to appraise the morbidity following PDO through a systematic review and meta-analysis. Methods: A systematic search of MEDLINE, Embase, and Web Of Science identified studies reporting outcomes of PDO following pancreaticoduodenectomy. Pooled prevalence rates of postoperative complications and mortality were computed using random-effect modeling. Meta-regression analyses were performed to examine the impact of moderators on the overall estimates. Results: Sixteen studies involving 1000 patients were included. Pooled postoperative mortality was 2.7%. A POPF was reported in 29.7% of the patients. Clinically relevant POPFs occurred in 13.5% of the patients, while intra-abdominal abscess and haemorrhages occurred in 6.7% and 5.5% of the patients, respectively. Re-operation was necessary in 7.6% of the patients. Postoperatively new onset diabetes occurred in 15.8% of patients, more frequently after the use of chemical substances for PDO (p = 0.003). Conclusions: PDO is associated with significant morbidity including new onset of post-operative diabetes. The risk of new onset post-operative diabetes is associated with the use of chemical substance for PDO. Further evidence is needed to evaluate the potential benefits of PDO in patients at high risk of POPF

Cooperación Internacional en Ciencia y Tecnología : El caso de Argentina y Venezuela a través del INTI durante el periodo 2003-2008

Durante el periodo 2003-2007, las relaciones bilaterales con la República Bolivariana se instalaron en el centro de los debates de política exterior. El discurso que los mandatarios Néstor Kirchner y Hugo Chávez sostenían en favor de una mayor integración sudamericana, sus críticas al modelo neoliberal y a su necesidad de transformación; y las aspiraciones de mayores márgenes de autonomía nacional y regional, constituyeron algunos de los puntos centrales en el acercamiento entre Buenos Aires y Caracas. Esa nueva sintonía a nivel político dio lugar a la apertura de un intenso proceso de estrechamiento de los lazos entre Argentina y Venezuela, cuyas características permiten afirmar que se trata de una etapa histórica sin precedentes en la relación bilateral. Por ejemplo, durante ese periodo se suscribieron alrededor del 60% del total de los acuerdos bilaterales. En ese marco, se produjo la firma de una serie de convenios de en materia de cooperación científica y-tecnológica, en los cuales se plantearon como objetivo el establecimiento de vinculaciones con organismos de investigación o desarrollo tecnológico de ambos países para promover el intercambio de profesionales, técnicos, productores para compartir experiencias y fomentar la cooperación y el desarrollo. Es ese sentido, y considerando el estrechamiento de los vínculos bilaterales, el objetivo de la presente investigación será analizar los programas de cooperación entre ambos países implementados a través del Instituto Nacional de Tecnología Industrial (INTI) durante el periodo 2003-2007.Expositores virtualesInstituto de Relaciones Internacionales (IRI

Cooperación Internacional en Ciencia y Tecnología : El caso de Argentina y Venezuela a través del INTI durante el periodo 2003-2008

Durante el periodo 2003-2007, las relaciones bilaterales con la República Bolivariana se instalaron en el centro de los debates de política exterior. El discurso que los mandatarios Néstor Kirchner y Hugo Chávez sostenían en favor de una mayor integración sudamericana, sus críticas al modelo neoliberal y a su necesidad de transformación; y las aspiraciones de mayores márgenes de autonomía nacional y regional, constituyeron algunos de los puntos centrales en el acercamiento entre Buenos Aires y Caracas. Esa nueva sintonía a nivel político dio lugar a la apertura de un intenso proceso de estrechamiento de los lazos entre Argentina y Venezuela, cuyas características permiten afirmar que se trata de una etapa histórica sin precedentes en la relación bilateral. Por ejemplo, durante ese periodo se suscribieron alrededor del 60% del total de los acuerdos bilaterales. En ese marco, se produjo la firma de una serie de convenios de en materia de cooperación científica y-tecnológica, en los cuales se plantearon como objetivo el establecimiento de vinculaciones con organismos de investigación o desarrollo tecnológico de ambos países para promover el intercambio de profesionales, técnicos, productores para compartir experiencias y fomentar la cooperación y el desarrollo. Es ese sentido, y considerando el estrechamiento de los vínculos bilaterales, el objetivo de la presente investigación será analizar los programas de cooperación entre ambos países implementados a través del Instituto Nacional de Tecnología Industrial (INTI) durante el periodo 2003-2007.Expositores virtualesInstituto de Relaciones Internacionales (IRI

High complication rate in Crohn's disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study

Intra-abdominal abscesses complicating Crohn's disease (CD) present an additional challenge as their presence can contraindicate immunosuppressive treatment whilst emergency surgery is associated with high stoma rate and complications. Treatment options include a conservative approach, percutaneous drainage, and surgical intervention. The current multicentre study audited the short-term outcomes of patients who underwent preoperative radiological drainage of intra-abdominal abscesses up to 6 weeks prior to surgery for ileocolonic CD

High complication rate in Crohn's disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study

Introduction: Intra-abdominal abscesses complicating Crohn's disease (CD) present an additional challenge as their presence can contraindicate immunosuppressive treatment whilst emergency surgery is associated with high stoma rate and complications. Treatment options include a conservative approach, percutaneous drainage, and surgical intervention. The current multicentre study audited the short-term outcomes of patients who underwent preoperative radiological drainage of intra-abdominal abscesses up to 6 weeks prior to surgery for ileocolonic CD. Methods: This is a retrospective, multicentre, observational study promoted by the Italian Society of Colorectal Surgery (SICCR), including all adults undergoing ileocolic resection for primary or recurrent CD from June 2018 to May 2019. The outcomes of patients who underwent radiological guided drainage prior to ileocolonic resection were compared to the patients who did not require preoperative drainage. Postoperative morbidity within 30 days of surgery was the primary endpoint. Postoperative length of hospital stay (LOS) and anastomotic leak rate were the secondary outcomes. Results: Amongst a group of 575 included patients who had an ileocolic resection for CD, there were 36 patients (6.2%) who underwent abscess drainage prior to surgery. Postoperative morbidity (44.4%) and anastomotic leak (11.1%) were significantly higher in the group of patients who underwent preoperative drainage. Conclusions: Patients with Crohn's disease who require preoperative radiological guided drainage of intra-abdominal abscesses are at increased risk of postoperative morbidity and septic complications following ileocaecal or re-do ileocolic resection

Pure laparoscopic formal right hepatectomy versus anatomical posterosuperior segmental resections : a comparative study

Background: To analyze the differences in perioperative outcomes between laparoscopic formal right hepatectomies (RH) and laparoscopic anatomical posterosuperior (PS) resections, including segmentectomies in PS segment SVII and right posterior sectionectomies (segment VI and VII resection). Methods: A retrospective analysis of all patients undergoing laparoscopic formal RHs and anatomical PS resections, including segmentectomies in PS segment SVII and right posterior sectionectomies (segment VI and VII resection), between January 2010 and August 2017 was performed. The two groups were compared in terms of patients’ characteristics, intraoperative parameters, and short-term outcomes. Results: Sixty-eight patients were included of which 32 RHs and 36 anatomical PS resections. In the PS resection group, 18 had a segmentectomy of segment VII and 18 had a bisegmentectomy of both segments VI and VII. Patients’ preoperative data were comparable. The lesion size was higher in the RHs (P<0.001). A significant shorter operative time was found in the PS group: 280 [230–315] vs. 357 [300–463] min in the RH group (P<0.001). Blood loss was comparable: 520 [390–906] in the RHs vs. 560 [370–1,030] in the PS group (P=0.595). The overall morbidity rate was comparable being 25% in the RHs and 22.2% in the PS group (P=1.000). A longer length of stay (LOS) {7 [5–8] vs. 5 [4–7] days, P=0.012} and higher readmission rate (12.5% vs. 0%, P=0.044) was observed in the RHs compared to the PS cohort. Concerning surgical margins, the R0 rate was comparable in the two groups; 90.9% in the RHs vs. 95.2% in the PS group (P=1.000). Conclusions: When deemed feasible based on lesion position and size, the laparoscopic parenchyma-preserving approach using anatomical PS segmental resections is associated with shorter hospital stay and a lower readmission rate in respect to formal RH. Overall, short-term surgical parameters indicated that both procedures are safe and feasible in experienced hands, however both demand a great deal of technical expertise