3,678 research outputs found

    Monitoring English Sandhi Linking – A Study of Polish Listeners’ L2 Perception

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    This paper presents a set of word monitoring experiments with Polish learners of English. Listeners heard short recordings of native English speech, and were instructed to respond when they recognized an English target word that had been presented on a computer screen. Owing to phonological considerations, we compared reaction times to two types of vowel-initial words, which had been produced either with glottalization, or had been joined via sandhi linking processes to the preceding word. Results showed that the effects of the glottalization as a boundary cue were less robust than expected. Implications of these findings for models of L2 speech are discussed. It is suggested that the prevalence of glottalization in L1 production makes listeners less sensitive to its effects as a boundary cue in L2

    Data report: late Miocene to early Pliocene coccolithophore and foraminiferal preservation at Site U1338 from scanning electron microscopy

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    The late Miocene to early Pliocene carbonate-rich sediments recovered at Integrated Ocean Drilling Program (IODP) Site U1338 during the Expedition 320/321 Pacific Equatorial Age Transect (PEAT) program contain abundant calcareous nanno- and microfossils. Geochemical proxies from benthic and planktonic foraminiferal and coccolithophore calcite could be very useful at this location; however, good preservation of the calcite is crucial for the proxies to be robust. Here, we evaluate the preservation of specific benthic and planktonic foraminifer species and coccolithophores in fine fraction sediment at Site U1338 using backscattered electron (topography mode) scanning electron microscopy (BSE-TOPO SEM). Both investigated foraminiferal species, Cibicidoides mundulus and Globigerinoides sacculifer, have undergone some alteration. The C. mundulus show minor evidence for dissolution, and only some specimens show evidence of overgrowth. The Gs. sacculifer show definite signs of alteration and exhibit variable preservation, ranging from fair to poor; some specimens show minor overgrowth and internal recrystallization but retain original features such as pores, spine pits, and internal testwall growth structure, whereas in other specimens the recrystallization and overgrowth disguise many of the original features. Secondary electron and BSE-TOPO SEM images show that coccolith calcite preservation is moderate or moderate to poor. Slight to moderate etching has removed central heterococcolith features, and a small amount of secondary overgrowth is also visible. Energy dispersive spectroscopy analyses indicate that the main sedimentary components of the fine fraction sediment are biogenic CaCO3 and SiO2, with some marine barite. Based on the investigations in this data report, geochemical analyses on benthic foraminifers are unlikely to be affected by preservation, although geochemical analyses on the planktonic foraminifers should be treated cautiously because of the fair to poor and highly variable preservation

    Staying Tuned

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    Ethnographers today find themselves experimenting with new approaches to digital ethnography amid pandemic-related restrictions on research. Yet such developments only accelerate a broader trend toward the dissolution of the traditional ethnographic ‘field’ due to new com-munications technologies and the emergence of a globalized ‘knowledge economy’. Through six contributions from around the world, this forum explores how the emergence of a more diffuse, interconnected ethno-graphic field is impacting fieldwork’s status as a rite of passage, creating new affective entanglements and shifting power relationships between researchers and participants. Despite the potential for influence and surveillance that new technologies cede to already powerful institutions, the discussions underline how ethnographic interlocutors are auteurs in their own right—and that ethnographers are also often bit characters in other people’s stories

    Perception of allophonic cues to English word boundaries by Polish learners: Approximant devoicing in English

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    The study investigates the perception of devoicing of English /w, r, j, l/ after /p, t, k/ as a word-boundary cue by Polish listeners. Polish does not devoice sonorants following voiceless stops in word-initial positions. As a result, Polish learners are not made sensitive to sonorant devoicing as a segmentation cue. Higher-proficiency and lower-proficiency Polish learners of English participated in the task in which they recognised phrases such as buy train vs. bite rain or pie plot vs. pipe lot. The analysis of accuracy scores revealed that successful segmentation was only above chance level, indicating that sonorant voicing/devoicing cue was largely unattended to in identifying the boundary location. Moreover, higher proficiency did not lead to more successful segmentation. The analysis of reaction times showed an unclear pattern in which higher-proficiency listeners segmented the test phrases faster but not more accurately than lower-proficiency listeners. Finally, #CS sequences were recognised more accurately than C#S sequences, which was taken to suggest that the listeners may have had some limited knowledge that devoiced sonorants appear only in word-initial positions, but they treated voiced sonorants as equal candidates for word-final and word-initial position

    External Sandhi in L2 segmental phonetics - final (de)voicing in Polish English

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    The effects of external sandhi, phonological processes that span word boundaries, have been largely neglected in L2 speech research. The glottalization of word‐initial vowels in Polish may act as a “sandhi blocker” that prevents the type of liaison across word boundaries that is common in English (e.g. find out/fine doubt). This reinforces the context for another process, final obstruent devoicing, which is typical of Polish‐accented English. Clearly ‘initial’ and ‘final’ do not mean the same thing for the phonologies of the two languages. An adequate theory of phonological representation should be able to express these differences. This paper presents an acoustic study of the speech of voiced C#V sequences in Polish English. Results show that the acquisition of liaison, which entails suppression of the L1 vowel‐initial glottalization process, contributes to the error‐free production of final voiced obstruents, implying the internalization of cross‐language differences in boundary representatio

    Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3’ regulatory regions and its conservation in mammals

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    Regulatory regions in the genome can act through a variety of mechanisms that range from the occurrence of histone modifications to the presence of protein-binding loci for self-annealing sequences. The final result is often the induction of a conformational change of the DNA double helix, which alters the accessibility of a region to transcription factors and consequently gene expression. A similar to 300 kb regulatory region on chromosome 14 at the 3' end (3'RR) of immunoglobulin (Ig) heavy-chain genes shows very peculiar features, conserved in mammals, including enhancers and transcription factor binding sites. In primates, the 3'RR is present in two copies, both having a central enhancer named hs1.2. We previously demonstrated the association between different hs1.2 alleles and Ig plasma levels in immunopathology. Here, we present the analysis of a putative G-quadruplex structure (tetraplex) consensus site embedded in a variable number tandem repeat (one to four copies) of hs1.2 that is a distinctive element among the enhancer alleles, and an investigation of its three-dimensional structure using bioinformatics and spectroscopic approaches. We suggest that both the role of the enhancer and the alternative effect of the hs1.2 alleles may be achieved through their peculiar three-dimensional-conformational rearrangement

    The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction.

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    Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity. These capabilities make them ideal targets for developing novel methods of insect disease vector control. Little is known about the nature of SFPs in the viviparous tsetse flies (Diptera: Glossinidae), vectors of Human and Animal African trypanosomiasis. In tsetse, male ejaculate is assembled into a capsule-like spermatophore structure visible post-copulation in the female uterus. We applied high-throughput approaches to uncover the composition of the spermatophore in Glossina morsitans morsitans. We found that both male accessory glands and testes contribute to its formation. The male accessory glands produce a small number of abundant novel proteins with yet unknown functions, in addition to enzyme inhibitors and peptidase regulators. The testes contribute sperm in addition to a diverse array of less abundant proteins associated with binding, oxidoreductase/transferase activities, cytoskeletal and lipid/carbohydrate transporter functions. Proteins encoded by female-biased genes are also found in the spermatophore. About half of the proteins display sequence conservation relative to other Diptera, and low similarity to SFPs from other studied species, possibly reflecting both their fast evolutionary pace and the divergent nature of tsetse's viviparous biology

    Hepatitis B cure: From discovery to regulatory approval

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138245/1/hep29323.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138245/2/hep29323_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138245/3/hep29323-sup-0001-supptable1.pd

    Birds in peatswamp at Klias Forest Reserve and Environs, Sabah, Malaysian Borneo

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    Periodically from 1998-2004, we surveyed birds in the Klias Forest Reserve, which is one of the last remaining pockets of peatswamp in western Sabah. We report here on those surveys. We also review prior work on birds in peatswamp and swamp forest in the Klias-Sipitang region of Sabah as it relates to the conservation of habitat and birds specialized on peatswamp. Peatswamp forest is in jeopardy from development and fires throughout Borneo, and particularly in the Malaysian State of Sabah, which had very little to start. Peatswamp in the Klias area is of particular importance for conservation and bird watching because Klias is close to the main tourist center of Borneo, Kota Kinabalu, and is the only easily accessible site for reliable sightings of Hook-billed Bulbul (Setornis criniger), Grey-breasted Babbler, (Malacopteron albogulare), and Scarlet-breasted Flowerpecker (Prionochilus thoracicus) in Sabah
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