TAVI-in-homograft (TiH): open transcatheter aortic valve replacement in calcified aortic homograft case reports

Background Redo surgery in patient who underwent aortic valve replacement with an aortic homograft can result technically challenging because of the massive calcification of the conduit. Case presentation We present a case of a patient who underwent open surgery on cardiopulmonary bypass assistance to implant a standard transcatheter aortic bioprosthesis through aortotomy in an off-label procedure and we discuss its safety and feasibility. Conclusions The combination of open cardiac surgery and open trans-aortic implant of a transcatheter prosthesis may reduce the surgical risk shrinking the technical difficulties that the implantation of a standard surgical prosthesis would have given

Construction of an integrated consensus map of the Apple genome based on four mapping populations

An integrated consensus genetic map for apple was constructed on the basis of segregation data from four genetically connected crosses (C1¿=¿Discovery × TN10-8, C2¿=¿Fiesta × Discovery, C3¿=¿Discovery × Prima, C4¿=¿Durello di Forli × Fiesta) with a total of 676 individuals using CarthaGene® software. First, integrated female¿male maps were built for each population using common female¿male simple sequence repeat markers (SSRs). Then, common SSRs over populations were used for the consensus map integration. The integrated consensus map consists of 1,046 markers, of which 159 are SSR markers, distributed over 17 linkage groups reflecting the basic chromosome number of apple. The total length of the integrated consensus map was 1,032 cM with a mean distance between adjacent loci of 1.1 cM. Markers were proportionally distributed over the 17 linkage groups (¿ 2¿=¿16.53, df¿=¿16, p¿=¿0.41). A non-uniform marker distribution was observed within all of the linkage groups (LGs). Clustering of markers at the same position (within a 1-cM window) was observed throughout LGs and consisted predominantly of only two to three linked markers. The four integrated female¿male maps showed a very good colinearity in marker order for their common markers, except for only two (CH01h01, CH05g03) and three (CH05a02z, NZ02b01, Lap-1) markers on LG17 and LG15, respectively. This integrated consensus map provides a framework for performing quantitative trait locus (QTL) detection in a multi-population design and evaluating the genetic background effect on QTL expression

Apollineo e dionisiaco. La costituzione dilemmatica della formazione umana

The article deals with the dilemmatic constitution of the human formation between Apollonian and Dionysian. In the first place, the relationship and identity of three fundamental concepts of pedagogy is restored, that is, Bildung (formation), Erziehung (education) and Kultur (culture). After a significance of the Greek myth and its Nietzschean reading, the Apollonian and Dionysian instances are considered within a pedagogical-clinical reflection. The axial figure is the concept of transfiguration, around which revolve the dialectical categories of harmony and delirium, conformism and transgression, perception (of beauty) and liberation (of instinct), criticism and social clinic. The unity between the two cases, which perhaps resolves the dilemmatic constitution of the formation, is based on the principle of formation and on the concept of Fortbildung, which consists of taking Bildung beyond himself

Elastic Antiproton-Nucleus Scattering from Chiral Forces

Elastic scattering of antiprotons off He4, C12, and O16,18 is described for the first time with a consistent microscopic approach based on the calculation of an optical potential (OP) describing the antiproton-target interaction. The OP is derived using the recent antiproton-nucleon (p¯N) chiral interaction to calculate the p¯N t matrix, while the target densities are computed with the ab initio no-core shell model using chiral interactions as well. Our results are in good agreement with the existing experimental data and the results computed at different chiral orders of the p¯N interaction display a well-defined convergence pattern

Isolation of a Vibrio parahaemolyticus pandemic strain from a marine water sample obtained in the northern Adriatic

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The TNG Near Infrared Camera Spectrometer

NICS (acronym for Near Infrared Camera Spectrometer) is the near-infrared cooled camera-spectrometer that has been developed by the Arcetri Infrared Group at the Arcetri Astrophysical Observatory, in collaboration with the CAISMI-CNR for the TNG (the Italian National Telescope Galileo at La Palma, Canary Islands, Spain). As NICS is in its scientific commissioning phase, we report its observing capabilities in the near-infrared bands at the TNG, along with the measured performance and the limiting magnitudes. We also describe some technical details of the project, such as cryogenics, mechanics, and the system which executes data acquisition and control, along with the related software.Comment: 7 pages, 5 figures, compiled with A&A macros. A&A in pres

Clinical Toxoplasmosis in Dogs and Cats: An Update

Toxoplasmosis is caused by the globally distributed protozoan parasite Toxoplasma gondii (phylum Apicomplexa); the disease can be clinically important for almost all homeothermic animals, including birds and humans. Toxoplasmosis course involves general clinical signs, such as fever, anorexia, or dyspnea, and more specific signs with neural, respiratory, cutaneous, or ocular involvement. Because of the wide range of clinical signs, the diagnosis in domestic and pet animals can be complicated. Hence, this review aims to provide a comprehensive analysis of some scarcely discussed aspects of toxoplasmosis, such as ocular and cutaneous manifestations, congenital infections, influence of T. gondii genotype on clinical toxoplasmosis, and recent findings regarding differential diagnosis. This review could be of special interest to clinicians and researchers