Análisis Comparativo del Resultado Económico-Patrimonial en Empresa Familiar y No Familiar: El Caso del Sector Servicios en Málaga (España)

This research explores the differences between the main economic financial ratios of family firms and non-family firms. The analysis has been carried out on a total of 335 firms from within the province of Malaga, of which 154 are family firms, with the remaining 181 being non-family firms. The sector that is the subject of this study is the tertiary sector: choosing bars, cafes and wholesale providers of these type of businesses due to their evident importance to the service sector in the province. Among main results, significant differences are highlighted in all the ratios analysed between the two groups of firms studied, as well as a greater distribution of profits to its shareholders by family firms (FF) versus non-family firms (NFF). Results show NFF have relatively higher economic return, although the variation of this ratio is greater than in a family firm.El presente trabajo refleja un análisis comparativo en los principales ratios económicos-financieros de las empresas familiares y no familiares, se ha realizado sobre un total de 335 empresas de la provincia de Málaga, de las cuales 154son familiares y otras 181no familiares. El sector que se ha estudiado es el terciario, escogiendo bares, cafeterías y los proveedores al por mayor de este tipo de comercios por su evidenteimportancia del sector servicios en esta provincia. Entre los principales resultados destacan las diferencias significativas en todos los ratios analizados entre los dos grupos de empresas estudiados, el mayor repartode beneficios a sus accionistas por parte de las empresas no familiares frente a las no familiares. Las empresas no familiares obtienen mayor rentabilidad económica relativamente, aunque la variación de este ratio es mayor que en las familiares. Diversas son las aplicaciones prácticas de los resultados del estudio para el sector terciario

High frequency of low-count monoclonal B-cell lymphocytosis in hospitalized COVID-19 patients

Low-count monoclonal B-cell lymphocytosis (MBLlo, <500 clonal B-cells/μL) is a highly prevalent condition in the general population (4% to 16% of otherwise healthy adults), which increases significantly with age.1-7 In most cases, clonal B-cells share phenotypic and cytogenetic features with chronic lymphocytic leukemia (CLL), but only a small fraction (≈1.8%) progresses to high-count MBL (MBLhi; ≥500 and <5000 clonal B-cells/μL)3 in the medium-term.8 However, previous reports showed that MBLlo subjects had an increased risk of severe infections in association with a (predominantly) secondary antibody deficiency,8-10 suggesting that MBLlo might be a risk marker for developing more severe infections.This work was supported by the Instituto de Salud Carlos III (Ministerio de Ciencia e Innovación, Madrid, Spain, and FONDOS FEDER (a way to build Europe) grants CB16/12/00400 (CIBERONC), COV20/00386, and PI17/00399; the Consejería de Educación and the Gerencia Regional de Salud, Consejería de Sanidad from Junta de Castilla y León (Valladolid, Spain) grants SA109P20 and GRS-COVID-33/A/20; the European Regional Development Fund (INTERREG POCTEP Spain-Portugal) grant 0639-IDIAL-NET-3-3; and the CRUK (United Kingdom), Fundación AECC (Spain), and Associazione Italiana per la Ricerca Sul Cancro (Italy) “Early Cancer Research Initiative Network on MBL (ECRINM3)” ACCELERATOR award. G.O.-A. is supported by a grant from the Consejería de Educación, Junta de Castilla y León (Valladolid, Spain); B.F.-H. was supported by grant 0639-IDIAL-NET-3-3.Peer reviewe

Immune cell kinetics and antibody response in COVID-19 patients with low-count monoclonal B-cell lymphocytosis

Low-count monoclonal B-cell lymphocytosis (MBLlo) has been associated with an underlying immunodeficiency and has recently emerged as a new risk factor for severe COVID-19. Here, we investigated the kinetics of immune cell and antibody responses in blood during COVID-19 of MBLlo versus non-MBL patients. For this study, we analyzed the kinetics of immune cells in blood of 336 COVID-19 patients (74 MBLlo and 262 non-MBL), who had not been vaccinated against SARS-CoV-2, over a period of 43 weeks since the onset of infection, using high-sensitivity flow cytometry. Plasma levels of anti-SARS-CoV-2 antibodies were measured in parallel by ELISA. Overall, early after the onset of symptoms, MBLlo COVID-19 patients showed increased neutrophil, monocyte, and particularly, plasma cell (PC) counts, whereas eosinophil, dendritic cell, basophil, and lymphocyte counts were markedly decreased in blood of a variable percentage of samples, and with a tendency toward normal levels from week +5 of infection onward. Compared with non-MBL patients, MBLlo COVID-19 patients presented higher neutrophil counts, together with decreased pre-GC B-cell, dendritic cell, and innate-like T-cell counts. Higher PC levels, together with a delayed PC peak and greater plasma levels of anti-SARS-CoV-2-specific antibodies (at week +2 to week +4) were also observed in MBLlo patients. In summary, MBLlo COVID-19 patients share immune profiles previously described for patients with severe SARS-CoV-2 infection, associated with a delayed but more pronounced PC and antibody humoral response once compared with non-MBL patients.This work was supported by “Early Cancer Research Initiative Network on MBL (ECRINM3)” ACCELERATOR award (CRUK-UK-, Fundación AECC-Spain-and Associazione Italiana per la Ricerca Sul Cancro _Italy-), by the CB16/12/00400 (CIBERONC), COV20/00386, PI17/00399, and PI22/00674, grants from the Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación, (Madrid, Spain) co-funded by FONDOS FEDER, and by the SA109P20 (Consejería de Educación) and GRS-COVID-33/A/20 (Gerencia Regional de Salud, Consejería de Sanidad) grants from Junta de Castilla y León (Valladolid, Spain), by 0639-IDIAL-NET-3-3 grant (INTERREG POCTEP Spain-Portugal) from Fondo Europeo de Desarrollo Regional. G. Oliva-Ariza is supported by a grant (PR-2019 487971) from the Consejería de Educación, Junta de Castilla y León (Valladolid, Spain), B. Fuentes-Herrero is supported by the 0639-IDIAL-NET-3-3, and ECRIN-M3 grants, and Ó. González-López is supported by a grant (FI20/00116) from Instituto de Salud Carlos III co-funded by Fondo Social Europeo Plus (FSE+).Peer reviewe

¿Qué queda de mí?

Este libro es una reclamación a quienes hemos sido, somos o seremos docentes. A quienes no hemos respetado a las personas que se han puesto junto a nosotros y nosotras, confiando su bien más preciado: la libertad. Estas páginas denuncian cada vez que convertimos una visión en la visión, una emoción en la emoción, un saber en el saber, un comportamiento en el comportamiento. Es un grito contra la imposición, la normalización, la neutralización y la universalización de una perspectiva particular. Una pugna contra cada proceso que no se ha conectado con las vidas de los aprendices. Un texto colaborativo realizado por alumnado de Educación y Cambio Social en el Grado en Educación Infantil de la Universidad de Málaga y coordinado por Ignacio Calderón Almendros

Comparative analysis of the financial results-equity in family firms and non-family firms: the case of the service sector in Malaga (Spain)

This research explores the differences between the main economic financial ratios of family firms and non-family firms. The analysis has been carried out on a total of 335 firms from within the province of Malaga, of which 154 are of familiar type, with the remaining 181 being unfamiliar. The sector that is the subject of this study is the tertiary sector: choosing bars, cafes and wholesale providers of these type of businesses due to their evident importance to the service sector in the province. Among main results, significant differences are highlighted in all the ratios analysed between the two groups of firms studied, as well as a greater distribution of profits to its shareholders by family firms (FF) versus non-family firms (NFF). Results show NFF have relatively higher economic return, although the variation of this ratio is greater than in a family firmEl presente trabajo refleja un análisis comparativo en los principales ratios económicos-financieros de las empresas familiares y no familiares, se ha realizado sobre un total de 335 empresas de la provincia de Málaga, de las cuales 154son familiares y otras 181no familiares. El sector que se ha estudiado es el terciario, escogiendo bares, cafeterías y los proveedores al por mayor de este tipo de comercios por su evidente importancia del sector servicios en esta provincia. Entre los principales resultados destacan las diferencias significativas en todos los ratios analizados entre los dos grupos de empresas estudiados, el mayor repartode beneficios a sus accionistas por parte de las empresas no familiares frente a las no familiares. Las empresas no familiares obtienen mayor rentabilidad económica relativamente, aunque la variación de este ratio es mayor que en las familiares. Diversas son las aplicaciones prácticas de los resultados del estudio para el sector terciario

Moderate Water Stress Impact on Yield Components of Greenhouse Tomatoes in Relation to Plant Water Status

The scarcity of water resources affects tomato production. Deficit irrigation may optimize water management with only a low reduction in yield. Deficit irrigation scheduling based on applied water presented no clear conclusions. Water stress management based on plant water status, such as water potential, could improve the scheduling. The aim of this work was to evaluate the physiological and yield responses of different tomato cultivars to deficit irrigation. Three experiments were carried out in 2020 and 2022 at the University of Seville (Spain). “Cherry” and “chocolate Marmande” cultivars with an indeterminate growth pattern were grown in a greenhouse. Treatments were: Control (full irrigated) and Deficit. Deficit plants were irrigated based on water potential measurements. Moderate water stress did not significantly reduce the yield, although it affected other processes. Fruit size and total soluble solids were the most sensitive parameters to water stress. The latter increased only when persistent water stress was applied. However, truss development and fruit number were not affected by the level of water stress imposed. Such results suggest that moderate water stress, even in sensitive phenological stages such as flowering, would not reduce yield. Deficit irrigation scheduling based on plant water status will allow accurate management of water stress