Participatory Technology and Constraints Assessment to Improve the Livelihood of Beekeepers in Tigray Region, northern Ethiopia

Beekeeping is a long-standing practice in the rural communities of Ethiopia and appears as ancient history of the country. A three–part assessment and diagnostic study (Livelihood systems assessment, integrated honeybee management needs assessment and diagnostic survey) was undertaken from 2006-2008 in Tigray, Ethiopia to identify market and technological constraints facing the honey sub sector and asses bee pests and the control measures taken. Information was gathered through PRA, interview with key informants and integrated honeybee management diagnostic survey in the rural areas. The assessment and diagnostic activities were undertaken in six zones (Western, North western, Central, Eastern, Southern and Southeastern zones of the region). One hundred nineteen beekeepers were randomly selected. Information on the adoption of new technology, availability of honeybee pests, average annual harvest of honey, honeybee pest controlling measures, market and technological constraints etc. were sought from the beekeepers. Honey yield was markedly different for the traditional and modern hives. On average, it was about 8-15 kg/hive and 20-30 kg/hive from the traditional and modern hives respectively. Lack of adequate bee forages, poor market, lack of trained development agents, inadequate government support, bee pests and inadequate training are mainly the problems facing the honey sub sector in the region. There are different kinds of bee pests and predators. Honey is harvested twice a year. From this study it was realized that almost all beekeeping practices are traditional except little intervention with improved beekeeping practices. Key words: Beekeeping, Bee management, Beehive, Tigray

The Genetics of Adverse Drug Outcomes in Type 2 Diabetes:A Systematic Review

Background: Adverse drug reactions (ADR) are a major clinical problem accounting for significant hospital admission rates, morbidity, mortality, and health care costs. One-third of people with diabetes experience at least one ADR. However, there is notable interindividual heterogeneity resulting in patient harm and unnecessary medical costs. Genomics is at the forefront of research to understand interindividual variability, and there are many genotype-drug response associations in diabetes with inconsistent findings. Here, we conducted a systematic review to comprehensively examine and synthesize the effect of genetic polymorphisms on the incidence of ADRs of oral glucose-lowering drugs in people with type 2 diabetes. Methods: A literature search was made to identify articles that included specific results of research on genetic polymorphism and adverse effects associated with oral glucose-lowering drugs. The electronic search was carried out on 3rd October 2020, through Cochrane Library, PubMed, and Web of Science using keywords and MeSH terms. Result: Eighteen articles consisting of 10, 383 subjects were included in this review. Carriers of reduced-function alleles of organic cation transporter 1 (OCT 1, encoded by SLC22A1) or reduced expression alleles of plasma membrane monoamine transporter (PMAT, encoded by SLC29A4) or serotonin transporter (SERT, encoded by SLC6A4) were associated with increased incidence of metformin-related gastrointestinal (GI) adverse effects. These effects were shown to exacerbate by concomitant treatment with gut transporter inhibiting drugs. The CYP2C9 alleles, (*)2 (rs1799853C>T) and (*)3 (rs1057910A>C) that are predictive of low enzyme activity were more common in subjects who experienced hypoglycemia after treatment with sulfonylureas. However, there was no significant association between sulfonylurea-related hypoglycemia and genetic variants in the ATP-binding cassette transporter sub-family C member 8 (ABCC8)/Potassium Inwardly Rectifying Channel Subfamily J Member 11 (KCNJ11). Compared to the wild type, the low enzyme activity C allele at CYP2C8(*)3 (rs1057910A>C) was associated with less weight gain whereas the C allele at rs6123045 in the NFATC2 gene was significantly associated with edema from rosiglitazone treatment. Conclusion: In spite of limited studies investigating genetics and ADR in diabetes, some convincing results are emerging. Genetic variants in genes encoding drug transporters and metabolizing enzymes are implicated in metformin-related GI adverse effects, and sulfonylurea-induced hypoglycemia, respectively. Further studies to investigate newer antidiabetic drugs such as DPP-4i, GLP-1RA, and SGLT2i are warranted. In addition, pharmacogenetic studies that account for race and ethnic differences are required

Co-producing Gender-responsive Climate Services for Enhanced Food and Nutrition Security and Health in Ethiopia and Tanzania (COGENT) – Consultative Workshop for Ethiopia

The COGENT-Climate Services Consultative Workshop was conducted on May 27-28, 2022 in Yirba town, Boricha woreda. [Add some information on the aim and objectives, how many participants, from which institutions]. COGENT represents an inter-disciplinary approach to improving household food security and nutrition-related health outcomes among women and children in the face of climate change in selected areas of Ethiopia. Over the past decades, growing investments have been made in developing climate services that can help reduce societal vulnerabilities and enhance adaptation and resilience to the impacts of climate variability and change. The development of climate services rests on several assumptions. First, that providing more, and better climate information will enhance the uptake of this information into decision-making. Second, that the application of climate services will lead to improved development outcomes. COGENT aims to advance understanding of the key mechanisms that facilitate production of usable climate information, with the potential to improve the quality of climate services across other African contexts. It works to strengthen the long-term capacities of local institutions to undertake high-quality, policy-relevant research while simultaneously building new interdisciplinary networks and collaborative experience and expertise within the climate research community

Readiness of primary health care facilities in Jimma zone to provide diabetic services for diabetic clients, Jimma zone, southwest Ethiopia, March 2013

Published date: Oct 12, 2016Background: Diabetes is one of the commonest non-communicable diseases of the 21st century. Global burden of diabetes in 2010 was estimated at 285 million and projected to increase to 438 million by the year 2030, if no interventions are put in place. The primary health care facilities are the first level of contact for such rising cases of diabetes, despite of this fact there is no study done on the capabilities of primary health care facilities to accommodate diabetic services. Hence, the objective of this study is to assess the readiness of selected primary public hospitals and health centers to accommodate diabetic care in Jimma zone south west Ethiopia. Methods: Health facility based cross-sectional study design using quantitative and qualitative method of data collection was conducted from Feb 1-March 1, 2013. After checking the completeness, and coding of questionnaires, the quantitative data were entered into computer software and analyzed using SPSS version 20.0. Results: All of the facilities have at least some of the drugs and medical supplies and other resources required for the diagnosis and management of diabetes never the less there was no specific plan to deal with diabetic management at health facilities. Majority of patients were first diagnosed in other health facilities and referred to the current health institutions for follow up and there is no routine screening for diabetics in adult outpatient department in some health facilities. Conclusion and recommendation: Required drugs and medical supplies are not regularly fulfilled, health facilities have no plan for diabetic management, and health workers did not get training on management of diabetics. No routine screening at adult patients at outpatient departments. Hence the Woreda and the zone have to work on the capacity of the health workers and health facilities to handle diabetic care at health center level.Fikru Tafese, Elias Teferi, Beyene Wondafirash, Sintayehu Fekadu, Garumma Tolu and Gugsa Nemarr

Free roaming dogs and the communities’ knowledge, attitude and practices of rabies incidence/human exposures: Cases of selected settings in Ethiopia and Kenya

AbstractBackground: According to the recommendation made by World Health organization, vaccinating 70% of the dog population helps to control rabies and prevent rabies virus in human population. However, the exponential increase in the population of free roaming dogs is a serious challenge to this strategy in Eastern African countries including Ethiopia and Kenya. Understanding the dynamics of free roaming dog populations is, thus, a step to be taken prior to designing effective rabies prevention and control strategy in these countries.Objectives: The present study was designed to determine the number of free roaming dogs in selected settings in Ethiopia and Kenya, and describe the level of community knowledge, attitude and practice (KAP) on rabies incidence/human exposures. The study also described the socio-cultural value of dog keeping in the areas considered in the study.Methodology: Counting free roaming dogs were a major means of collecting data in both Ethiopia and Kenya. Dog count was made using the markup capture approach. Other than counting, questionnaire was used to obtain data for the study. Three-hundred and ninety-eight copies of questionnaires were administered to the study participants in Ethiopia, while the number of respondents to the questionnaire in Kenya was 351. In addition, a five-year retrospective data on dog/animal bite cases were collected from selected health facilities of the study sites.Results: A total of 2991 and 386 free roaming dogs were counted in Ethiopia and Kenya, respectively. A five-year retrospective data showed cases of 1524 (in Mekelle) and 429 (Assela) individuals who were bitten/infected by rabies-suspected animals. Evidence obtained from the health facilities in Mekelle and Assela showed the bitten/infected individuals took PEP within the specified period.In Kenya, a total of 3441 and 4997 animal bite cases were reported from 2010-2014 in Kisumu and Siaya, respectively. The number of animal bite cases may signify the economic burden incurred (cost of PEP and other related costs), public health impact and social value of the disease. The questionnaire data also indicated the existing dog management practices, awareness of the community about rabies and its zoonotic importance, the first line of action taken at home for individuals bitten by rabies suspected animal, awareness of the community on dog vaccination, importance of free roaming dogs and their management.Conclusion: The significant proportion of free roaming dogs and number of animal bite cases calls for an integrated action between human and veterinary professionals to control the number of free roaming dog population, initiate awareness creation programs in the community and increase the vaccination of owned dogs there by to control and prevent rabies. Ethiop. J. Health Dev. 2018;32(1):27-35

Assessment of Knowledge and Practices Toward COVID-19 Prevention Among Healthcare Workers in Tigray, North Ethiopia

Background: The incidence rate of coronavirus disease 2019 (COVID-19) is increasing in several countries despite that public health measures are put in place. Given that COVID-19 is a newly emerging disease, there is little knowledge about the disease. The present study aims to assess knowledge, perception, and preventive practices toward COVID-19 among health workers in Tigray, North Ethiopia.Materials and Methods: A health facility-based cross-sectional study was conducted among health professionals working in public hospitals. Data were collected between April and May 2020. The researchers included 403 participants and recruited them via a simple random sampling technique. To collect data, the researchers prepared a structured questionnaire guided by the WHO survey questions. Data were entered into Epi-info 7 and exported to SPSS version 20.00 for analysis. The researchers applied descriptive and inferential statistical analyses. Tables and graphs were used to describe data, and multivariate binary logistic regression was used to determine factors affecting knowledge, perception, and practices toward COVID-19 prevention.Results: Among the participants, 79, 88, and 64.3% of them had adequate knowledge, positive perception, and good practice toward preventing COVID-19, respectively. Besides, 92% of the study participants knew that the COVID-19 virus does not have curative treatment and vaccine. The findings revealed that 55% of the respondents did not use the necessary personal protective equipment (PPE) at all times. The result showed that being female [AOR: 2.43, 95% CI (1.50–3.94)] and having a work experience of 2–5 years [AOR: 2.44, 95% CI (1.10–5.39)], news media as a source information [AOR: 7.11, 95% CI (3.07–16.49)], social media as a source information [AOR: 4.59, 95% CI (2.15–9.84)], and governmental website as a source information [AOR: 4.21, 95% CI (2.15–8.27)] were reported as protective factors; and being single [AOR: 0.15, 95% CI (0.03–0.75)] was reported as risk factor toward the prevention of COVID-19.Conclusion: Most health workers had adequate knowledge and positive attitude toward COVID-19; nevertheless, a significant proportion of health workers had poor practice toward the prevention of COVID-19, including the use of PPE. Additionally, some groups of health professional showed poor practices of implementing the public health measures, hence the call for them to improve in the prevention and control of COVID-19