2,989 research outputs found

    Analysis of the Workforce and Workplace for Rheumatology, and the Research Activities of Rheumatologists Early in Their Careers

    Get PDF
    [Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snapshots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry. As a consequence, the workforce and workplace for clinical investigation is enigmatic and unexamined even after explicit warnings that an essential arm for advancing clinical practice has been disabled. The present study was designed to assess the workforce and workplace for rheumatology, and the extent and type of research prevailing among rheumatologists early in their careers. Our findings provide fresh insights about the workforce and the workplace for rheumatology, and justify interventions to address gaps in both the scope and scale of clinical research in arthritis and rheumatism

    The Scope and Scale of Clinical Research Accomplished by Rheumatologists Early in Their Careers

    Get PDF
    [Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snap shots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry. As a consequence, the workforce and workplace for clinical investigation is enigmatic and unexamined even after explicit warnings that an essential arm for advancing clinical practice is disabled. The present study was designed to examine the nature and extent of investigative activity prevailing among rheumatologists early in their careers. This assessment provides a lens on: i) the fraction of early career rheumatologists who engage in investigative rheumatology, ii) the scope and scale of research in musculoskeletal diseases, iii) funding available for investigative work, iv) the impact of research-intensive institutions, and NIH-K-series awards on research, and v) the demographic backgrounds of early career rheumatologists. The results provide important new insights about the early career workforce for discovery and innovation in rheumatology. The findings integrate demographic, normative, and predictive data to provide the first estimate of the scope and scale of clinical investigation within rheumatology. The results also justify interventions for promoting investigative work, and ultimately advancing the clinical practice of rheumatology

    The Antagonistic Effect of Strontium Ions for Anesthetization of Paramecium caudatum with Nickel lons

    Get PDF
    The purpose of this investigation was (1) to compute the effects of strontium ion antagonism and the observed biological effect of the strontium ion for anestesia of Paramecium caudatum with the nickel ion, (2) to compare the prolonged effect of the strontium ion antagonism for nickel ions upon the vitality of P. caudatum for control groups using the fission rate as an index of vitality. The experimental data showed a biological antagonism of the strontium ions for the nickel ions in anesthetization of P. caudatum. Further, the vitality study showed that the presence of strontium ions reduced the inhibitory effect of nickel ions for fission of P. caudatum

    Invited commentary

    Get PDF

    Accidents in rural Ohio, 1977

    Get PDF

    CAA study of airfoil broadband interaction noise using stochastic turbulent vorticity sources

    Get PDF
    The interaction of the turbulent wakes of the rotor with the outer guide vanes is one of the main broadband noise source in turbofan engines at approach conditions. Hence its prediction and reduction is a priority for engine manufacturers. The development of numerical methods is required as analytical approaches are limited to simple geometries and simplified flow configurations. The linearized Euler equations are solved in the time-domain to model the response of an isolated airfoil interacting with turbulence that is stochastically synthesized and injected in the computational domain through vorticity sources. This new method of injection has the advantages of being easy to implement and parallelize in an existing solver, whilst the generated turbulence is frozen. The method is firstly validated on a 2D free-field configuration. It is then applied, in the framework of the Fan Stage Broadband Noise Benchmarking Programme, to a two-dimensional NACA 65(12)-10 airfoil with no angle of attack and the results are validated through comparisons with experimental data. Afterwards, the effect of the angle of attack is studied and the results suggest that a one-component turbulent model is not satisfactory to perform accurate acoustic predictions with an angle of attack, as it overestimates the rate of decay of the acoustic spectra at high frequencies. The study of the influence of the integral length scale of the turbulence confirms that the airfoil leading edge response is only modulated by the incoming turbulence characteristics. Finally, the acoustic spectra predicted for different velocities show a better agreement with a flat plate analytical model when the velocity is increased

    Fauna of the Middle Little Sioux River and Comparison with Upper and Lower Regions

    Get PDF
    A species list of macroscopic animals is compiled for the middle portion of the Little Sioux River, Iowa. These are tabulated along with published data from regions of the river above and below. The Little Sioux meanders throughout a valley of largely agricultural landscape; it has a relatively high silt load. Chemical differences are not great; some effects of municipal effluent are noted. The number of species is relatively constant (in the 40-60 range); numbers in the uppermost, intermittent stretches and the lowermost, channelized segment are lower (30- 40). Only about 20% of the species are ubiquitous; trends of diversity and distribution are noted in the invertebrates and fishes
    • …
    corecore