13,741 research outputs found
Shared Leadership in Higher Education: A Phenomenological Case-Study of the Impact of Shared Leadership on the Admission and Transfer Staff at a Regional Comprehensive State University
This exploratory research project was structured as a case study which sought to analyze the impact on relevant staff members of a comprehensive public university of a shared leadership model being applied to a transfer student recruitment program
Recommended from our members
The growth and saturation of submesoscale instabilities in the presence of a barotropic jet
AbstractMotivated by recent observations of submesoscales in the Southern Ocean, we use nonlinear numerical simulations and a linear stability analysis to examine the influence of a barotropic jet on submesoscale instabilities at an isolated front. Simulations of the nonhydrostatic Boussinesq equations with a strong barotropic jet (approximately matching the observed conditions) show that submesoscale disturbances and strong vertical velocities are confined to a small region near the initial frontal location. In contrast, without a barotropic jet, submesoscale eddies propagate to the edges of the computational domain and smear the mean frontal structure. Several intermediate jet strengths are also considered. A linear stability analysis reveals that the barotropic jet has a modest influence on the growth rate of linear disturbances to the initial conditions, with at most a ~20% reduction in the growth rate of the most unstable mode. On the other hand, a basic state formed by averaging the flow at the end of the simulation with a strong barotropic jet is linearly stable, suggesting that nonlinear processes modify the mean flow and stabilize the front.</jats:p
Infant cortex responds to other humans from shortly after birth
A significant feature of the adult human brain is its ability to selectively process information about conspecifics. Much debate has centred on whether this specialization is primarily a result of phylogenetic adaptation, or whether the brain acquires expertise in processing social stimuli as a result of its being born into an intensely social environment. Here we study the haemodynamic response in cortical areas of newborns (1–5 days old) while they passively viewed dynamic human or mechanical action videos. We observed activation selective to a dynamic face stimulus over bilateral posterior temporal cortex, but no activation in response to a moving human arm. This selective activation to the social stimulus correlated with age in hours over the first few days post partum. Thus, even very limited experience of face-to-face interaction with other humans may be sufficient to elicit social stimulus activation of relevant cortical regions
Dark Matter: The Leptonic Connection
Recent observatons of high-energy positrons and electrons by the PAMELA and
ATIC experiments may be an indication of the annihilation of dark matter into
leptons and not quarks. This leptonic connection was foreseen already some
years ago in two different models of radiative neutrino mass. We discuss here
the generic interactions (nu eta^0 - l eta^+) chi and l^c zeta^- chi^c which
allow this to happen, where chi and/or chi^c are fermionic dark-matter
candidates. We point out in particular the importance of chi chi to l^+ l^-
gamma to both positron and gamma-ray signals within this framework.Comment: 4 pages, 5 figures. v2: PLB versio
Three‐dimensional, multispecies, high spatial resolution MHD studies of the solar wind interaction with Mars
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95232/1/jgra17355.pd
The Toxoplasma gondii Cyst Wall Protein CST1 Is Critical for Cyst Wall Integrity and Promotes Bradyzoite Persistence
Toxoplasma gondii infects up to one third of the world\u27s population. A key to the success of T. gondii as a parasite is its ability to persist for the life of its host as bradyzoites within tissue cysts. The glycosylated cyst wall is the key structural feature that facilitates persistence and oral transmission of this parasite. Because most of the antibodies and reagents that recognize the cyst wall recognize carbohydrates, identification of the components of the cyst wall has been technically challenging. We have identified CST1 (TGME49_064660) as a 250 kDa SRS (SAG1 related sequence) domain protein with a large mucin-like domain. CST1 is responsible for the Dolichos biflorus Agglutinin (DBA) lectin binding characteristic of T. gondii cysts. Deletion of CST1 results in reduced cyst number and a fragile brain cyst phenotype characterized by a thinning and disruption of the underlying region of the cyst wall. These defects are reversed by complementation of CST1. Additional complementation experiments demonstrate that the CST1-mucin domain is necessary for the formation of a normal cyst wall structure, the ability of the cyst to resist mechanical stress, and binding of DBA to the cyst wall. RNA-seq transcriptome analysis demonstrated dysregulation of bradyzoite genes within the various cst1 mutants. These results indicate that CST1 functions as a key structural component that confers essential sturdiness to the T. gondii tissue cyst critical for persistence of bradyzoite forms
- …