Stability estimates for an inverse scattering problem at high frequencies

We consider an inverse scattering problem and its near-field approximation at high frequencies. We first prove, for both problems, Lipschitz stability results for determining the low-frequency component of the potential. Then we show that, in the case of a radial potential supported sufficiently near the boundary, infinite resolution can be achieved from measurements of the near-field operator in the monotone case

Scenario planning with mobile payments in emerging markets

CEM

A ameaça de atores não estatais aos estados nacionais: estudo de caso acerca das organizações narcotraficantes mexicanas entre 2006 e 2012

TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Relações Internacionais.Assim como as ameaças de outros atores não-estatais, a ameaça dos grupos narcotraficantes transnacionais se confunde entre as fronteiras da segurança pública e nacional. Embora sejam atores cuja ação é fundamentalmente exercida dentro das fronteiras de um Estado, as características da cadeia produtiva do mercado das drogas bem como o tamanho da demanda por drogas levaram as organizações narcotraficantes transnacionais a funcionarem com operações altamente sofisticadas, capazes de constituírem algum nível de autoridade e controle nos espaços onde operam. A partir desse processo, elas também passaram a apresentarem-se como desafios para o combate e controle por parte dos Estados Nacionais, os quais encontraram resultados paradoxais às suas principais estratégias jurídicas e militares de proibição no consumo e comercialização das drogas. Reconhecendo o impacto do desenvolvimento de organizações narcotraficantes e o desafio que elas impõem aos Estados, este estudo busca entender as principais características da dinâmica de coexistência entre os dois agentes, em especial no tocante às questões de segurança pública e nacional. Através do estudo de caso do conflito entre as organizações narcotraficantes mexicanas e o Estado sob o governo de Felipe Calderón (2006-2012), pretende-se entender se as estratégias adotadas pelos Estados Nacionais no combate a ameaça desses grupos tendem a intensificar as dinâmicas de insegurança pública, transformando a questão do narcotráfico em um dilema de segurança nacional. Conclui-se que, apesar de ser verdadeira a afirmação de que as ações combativas dos Estados intensificam o processo de geração de insegurança pública, as organizações narcotraficantes transnacionais não são atores que ameaçam a segurança nacional dos Estados

Concise Review: Salivary Gland Regeneration: Therapeutic Approaches from Stem Cells to Tissue Organoids

The human salivary gland (SG) has an elegant architecture of epithelial acini, connecting ductal branching structures, vascular and neuronal networks that together function to produce and secrete saliva. This review focuses on the translation of cell‐ and tissue‐based research toward therapies for patients suffering from SG hypofunction and related dry mouth syndrome (xerostomia), as a consequence of radiation therapy or systemic disease. We will broadly review the recent literature and discuss the clinical prospects of stem/progenitor cell and tissue‐based therapies for SG repair and/or regeneration. Thus far, several strategies have been proposed for the purpose of restoring SG function: (1) transplanting autologous SG‐derived epithelial stem/progenitor cells; (2) exploiting non‐epithelial cells and/or their bioactive lysates; and (3) tissue engineering approaches using 3D (three‐dimensional) biomaterials loaded with SG cells and/or bioactive cues to mimic in vivo SGs. We predict that further scientific improvement in each of these areas will translate to effective therapies toward the repair of damaged glands and the development of miniature SG organoids for the fundamental restoration of saliva secretion. Stem Cells 2017;35:97–105Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135510/1/stem2455.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/135510/2/stem2455_am.pd

Sistema gerenciador de medicamentos da Associação Paranaense de Portadores de Parkinsonismo (SGM-APPP)

Orientador : Alexander Robert Kutzke.Monografia (Graduação) - Universidade Federal do Paraná. Setor de Educação Profissional e Tecnológica. Curso de Tecnologia em Análise e Desenvolvimento de Sistemas.Inclui referênciasResumo

DNA DAMAGE IN CANINE TRANSMISSIBLE VENEREAL TUMOR CELLS

The Transmissible Venereal Tumor (TVT) has been classified according to the predominant cell type as follows: lymphocytoid, plasmocytoid, and mixed. Various degrees of aggressiveness with large array of biological behaviour have been described according to the TVT cell lineages, the present study was designed to investigate the level of DNA damage in the three TVT cell types aiming a better understanding of mechanisms related to the aggressiveness of this neoplasia. A total of 35 dogs were evaluated, with no restriction regarding sex, age or breed, and with clinical and cytological diagnoses for TVT. Cell samples from the 35 tumoral neoplasmas were obtained by fine needle aspiration and taken to cytology and DNA damage analysis by the comet assay. From the 35 TVT cases, 12 (34.3%) were plasmocytoid, 11 (31.4%) lymphocytoid, and 12 (34.3%) mixed. Statistically significant (p<0.05) higher level of DNA damage was detected in lymphocytoid TVT cells when compared to the other two types

Comparison of Skin Prick Tests (SPT), Intradermal Tests (IDT) and In Vitro Tests in the Characterization of Insect Bite Hypersensitivity (IBH) in a Population of Lusitano Horses: Contribution for Future Implementation of SPT in IBH Diagnosis.

Thirty controls (C) and 30 IBH-affected (T) Lusitano horses were evaluated. T horses were included based on anamnesis and physical examination, supported by questionnaires. All horses were submitted to skin tests, Intrademal (IDT) and Skin Prick Tests (SPT), on the neck with 14 specific allergens, 13 recombinant proteins (r-proteins) from Culicoides nubeculosus (Cul n) and Culicoides obsoletus (Cul o) salivary glands and Culicoides nubeculosus Whole Body Extract (Cul n WBE). Addicionally, a cluster of six T and six C horses were also tested with Cul n 3 and Cul n 4 produced in insect cells and barley, as well as E. coli produced Cul o 3 and Cul o WBE. Allergen concentrations were 10 µg/mL for IDT and 100 µg/mL for SPT, and wheal diameters assessed at 20 min, 6 and 48 h. IDTs were considered positive when wheal diameter was ≥50% of the histamine wheal and SPT's ≥ 0.9 cm. In vitro tests, allergen-specific serum IgE and sulfidoleukotriene (sLT) release assay were also carried out. Results showed that Cul n WBE, Cul n 7, 8, 9, Cul o1P and Cul o 2P were the best performing allergens for SPTs (p ≤ 0.0001) for the 1st allergen panel and Cul o WBE, Cul n 3 Bar and Cul n 4 Bac (p ≤ 0.05) for the 2nd, presenting a higher discriminatory diagnostic potential than IDTs, at a concentration of 100 µg/mL, with readings assessed at 20 min. Regarding in vitro tests overall, the sLT release assay performed best