1,659 research outputs found

    Systematic perturbation approach for a dynamical scaling law in a kinetically constrained spin model

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    The dynamical behaviours of a kinetically constrained spin model (Fredrickson-Andersen model) on a Bethe lattice are investigated by a perturbation analysis that provides exact final states above the nonergodic transition point. It is observed that the time-dependent solutions of the derived dynamical systems obtained by the perturbation analysis become systematically closer to the results obtained by Monte Carlo simulations as the order of a perturbation series is increased. This systematic perturbation analysis also clarifies the existence of a dynamical scaling law, which provides a implication for a universal relation between a size scale and a time scale near the nonergodic transition.Comment: 17 pages, 7 figures, v2; results have been refined, v3; A figure has been modified, v4; results have been more refine

    Predicted waiting times for orthopaedic surgery : an urgent need to address the deficit in capacity

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    The authors received no financial or material support for the research, authorship, and/or publication of this article.Peer reviewedPublisher PD

    Galaxy and Mass Assembly (GAMA): Mid-infrared properties as tracers of galaxy environment

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    We investigate how different mid-infrared (mid-IR) properties of galaxies trace the environment in which the galaxies are located. For this purpose, we first study the dependence of galaxy clustering on the absolute magnitude at 3.4 ÎŒ\mum and redshift. Then, we look into the environmental dependence of mid-IR luminosities and the galaxy properties derived from these luminosities. We also explore how various infrared galaxy luminosity selections influence the galaxy clustering measurements. We use a set of W1 (3.4 ÎŒ\mum) absolute magnitude (MW1M_\text{W1}) selected samples from the Galaxy and Mass Assembly (GAMA) survey matched with mid-IR properties from the Wide-field Infrared Survey Explorer (WISE) in the redshift range 0.07≀z<0.430.07 \leq z < 0.43. We compute the galaxy two-point correlation function (2pCF) and compare the clustering lengths between subsamples binned in MW1M_\text{W1} and in redshift. We also measure the marked correlation functions (MCFs) using the luminosities in the WISE W1 to W4 (3.4 to 22 ÎŒ\mum) bands as marks. Additionally, we compare the measurements of MCFs with different estimates of stellar mass and star formation rate used as marks. Finally, we check how different selections applied to the sample affect the clustering measurements. We show strong clustering dependence on the W1 absolute magnitude: galaxies brighter in the W1 band are more strongly clustered than their fainter counterparts. We also observe a lack of significant redshift dependence of clustering in the redshift range 0.07≀z<0.430.07 \leq z < 0.43. We show that although W1 and W2 bands are direct indicators of stellar mass, a galaxy sample selected based on W1 or W2 bands does not perfectly show the clustering behaviour of a stellar mass selected sample. Similar is the case with the proxy relation between W3 and W4 bands and star formation rate.Comment: 19 pages, 12 figures, accepted in A&

    An Experimental and Theoretical Study of the Variation of 4f Hybridization Across the La1-xCexIn3 Series

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    Crystal structures of a series of La1-xCexIn3 (x = 0.02, 0.2, 0.5, or 0.8) intermetallic compounds have been investigated by both neutron and X-ray diffraction, and their physical properties have been characterized by magnetic susceptibility and specific heat measurements. Our results emphasize atypical atomic displacement parameters (ADP) for the In and the rare-earth sites. Depending on the x value, the In ADP presents either an "ellipsoidal" elongation (La-rich compounds) or a "butterfly-like" distortion (Ce-rich compounds). These deformations have been understood by theoretical techniques based on the band theory and are the result of hybridization between conduction electrons and 4f-electrons.Comment: 7 pages, 8 figure

    Seed systems smallholder farmers use

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    Seed can be an important entry point for promoting productivity, nutrition and resilience among smallholder farmers. While investments have primarily focused on strengthening the formal sector, this article documents the degree to which the informal sector remains the core for seed acquisition, especially in Africa. Conclusions drawn from a uniquely comprehensive data set, 9660 observations across six countries and covering 40 crops, show that farmers access 90.2 % of their seed from informal systems with 50.9 % of that deriving from local markets. Further, 55 % of seed is paid for by cash, indicating that smallholders are already making important investments in this arena. Targeted interventions are proposed for rendering formal and informal seed sector more smallholder-responsive and for scaling up positive impacts

    Breaching the delivery barrier: Chemical and physical airway epithelium disruption strategies for enhancing lentiviral-mediated gene therapy

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    Published: 26 April 2021The lungs have evolved complex physical, biological and immunological defences to prevent foreign material from entering the airway epithelial cells. These mechanisms can also affect both viral and non-viral gene transfer agents, and significantly diminish the effectiveness of airway gene-addition therapies. One strategy to overcome the physical barrier properties of the airway is to transiently disturb the integrity of the epithelium prior to delivery of the gene transfer vector. In this study, chemical (lysophosphatidylcholine, LPC) and physical epithelium disruption using wire abrasion were compared for their ability to improve airway-based lentiviral (LV) vector mediated transduction and reporter gene expression in rats. When luciferase expression was assessed at 1-week post LV delivery, LPC airway conditioning significantly enhanced gene expression levels in rat lungs, while a long-term assessment in a separate cohort of rats at 12 months revealed that LPC conditioning did not improve gene expression longevity. In rats receiving physical perturbation to the trachea prior to gene delivery, significantly higher LacZ gene expression levels were found when compared to LPC-conditioned or LV-only control rats when evaluated 1-week post gene transfer. This proof-of-principle study has shown that airway epithelial disruption strategies based on physical perturbation substantially enhanced LVmediated airway gene transfer in the trachea.Alexandra McCarron, Nigel Farrow, Patricia Cmielewski, Emma Knight, Martin Donnelley and David Parson

    OxyCAP UK: Oxyfuel Combustion - academic Programme for the UK

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    The OxyCAP-UK (Oxyfuel Combustion - Academic Programme for the UK) programme was a ÂŁ2 M collaboration involving researchers from seven UK universities, supported by E.On and the Engineering and Physical Sciences Research Council. The programme, which ran from November 2009 to July 2014, has successfully completed a broad range of activities related to development of oxyfuel power plants. This paper provides an overview of key findings arising from the programme. It covers development of UK research pilot test facilities for oxyfuel applications; 2-D and 3-D flame imaging systems for monitoring, analysis and diagnostics; fuel characterisation of biomass and coal for oxyfuel combustion applications; ash transformation/deposition in oxyfuel combustion systems; materials and corrosion in oxyfuel combustion systems; and development of advanced simulation based on CFD modelling

    Detection of a supervoid aligned with the cold spot of the cosmic microwave background

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    We use the WISE-2MASS infrared galaxy catalogue matched with Pan-STARRS1 (PS1) galaxies to search for a supervoid in the direction of the cosmic microwave background (CMB) cold spot (CS). Our imaging catalogue has median redshift z ≃ 0.14, and we obtain photometric redshifts from PS1 optical colours to create a tomographic map of the galaxy distribution. The radial profile centred on the CS shows a large low-density region, extending over tens of degrees. Motivated by previous CMB results, we test for underdensities within two angular radii, 5°, and 15°. The counts in photometric redshift bins show significantly low densities at high detection significance, ≳5σ and ≳6σ, respectively, for the two fiducial radii. The line-of-sight position of the deepest region of the void is z ≃ 0.15–0.25. Our data, combined with an earlier measurement by Granett, Szapudi & Neyrinck, are consistent with a large Rvoid = (220 ± 50) h−1 Mpc supervoid with ÎŽm ≃ −0.14 ± 0.04 centred at z = 0.22 ± 0.03. Such a supervoid, constituting at least a ≃3.3σ fluctuation in a Gaussian distribution of the Λ cold dark matter model, is a plausible cause for the CS
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