In situ analysis for intelligent control

We report a pilot study on in situ analysis of backscatter data for intelligent control of a scientific instrument on an Autonomous Underwater Vehicle (AUV) carried out at the Monterey Bay Aquarium Research Institute (MBARI). The objective of the study is to investigate techniques which use machine intelligence to enable event-response scenarios. Specifically we analyse a set of techniques for automated sample acquisition in the water-column using an electro-mechanical "Gulper", designed at MBARI. This is a syringe-like sampling device, carried onboard an AUV. The techniques we use in this study are clustering algorithms, intended to identify the important distinguishing characteristics of bodies of points within a data sample. We demonstrate that the complementary features of two clustering approaches can offer robust identification of interesting features in the water-column, which, in turn, can support automatic event-response control in the use of the Gulper

Do logarithmic proximity measures outperform plain ones in graph clustering?

We consider a number of graph kernels and proximity measures including commute time kernel, regularized Laplacian kernel, heat kernel, exponential diffusion kernel (also called "communicability"), etc., and the corresponding distances as applied to clustering nodes in random graphs and several well-known datasets. The model of generating random graphs involves edge probabilities for the pairs of nodes that belong to the same class or different predefined classes of nodes. It turns out that in most cases, logarithmic measures (i.e., measures resulting after taking logarithm of the proximities) perform better while distinguishing underlying classes than the "plain" measures. A comparison in terms of reject curves of inter-class and intra-class distances confirms this conclusion. A similar conclusion can be made for several well-known datasets. A possible origin of this effect is that most kernels have a multiplicative nature, while the nature of distances used in cluster algorithms is an additive one (cf. the triangle inequality). The logarithmic transformation is a tool to transform the first nature to the second one. Moreover, some distances corresponding to the logarithmic measures possess a meaningful cutpoint additivity property. In our experiments, the leader is usually the logarithmic Communicability measure. However, we indicate some more complicated cases in which other measures, typically, Communicability and plain Walk, can be the winners.Comment: 11 pages, 5 tables, 9 figures. Accepted for publication in the Proceedings of 6th International Conference on Network Analysis, May 26-28, 2016, Nizhny Novgorod, Russi

Smart Content Recognition from Images Using a Mixture of Convolutional Neural Networks

With rapid development of the Internet, web contents become huge. Most of the websites are publicly available, and anyone can access the contents from anywhere such as workplace, home and even schools. Nevertheless, not all the web contents are appropriate for all users, especially children. An example of these contents is pornography images which should be restricted to certain age group. Besides, these images are not safe for work (NSFW) in which employees should not be seen accessing such contents during work. Recently, convolutional neural networks have been successfully applied to many computer vision problems. Inspired by these successes, we propose a mixture of convolutional neural networks for adult content recognition. Unlike other works, our method is formulated on a weighted sum of multiple deep neural network models. The weights of each CNN models are expressed as a linear regression problem learned using Ordinary Least Squares (OLS). Experimental results demonstrate that the proposed model outperforms both single CNN model and the average sum of CNN models in adult content recognition.Comment: To be published in LNEE, Code: github.com/mundher/NSF

Association of ADRB2 rs1042713 with Obesity and Obesity-Related Phenotypes and Its Interaction with Dietary Fat in Modulating Glycaemic Indices in Malaysian Adults

Gene-diet interaction studies have reported that individual variations in phenotypic traits may be due to variations in individual diet. Our study aimed to evaluate (i) the association of ADRB2 rs1042713 with obesity and obesity-related metabolic parameters and (ii) the effect of dietary nutrients on these associations in Malaysian adults. ADRB2 genotyping, dietary, physical activity, anthropometric, and biochemical data were collected from 79 obese and 99 nonobese individuals. Logistic regression revealed no association between ADRB2 rs1042713 and obesity (p = 0.725). However, the carriers of G allele (AG + GG genotypes) of rs1042713 were associated with increased odds of insulin resistance, 2.83 (CI = 1.04–7.70, adjusted p = 0.042), in the dominant model, even after adjusting for potential confounders. Obese individuals carrying the G allele were associated with higher total cholesterol (p = 0.011), LDL cholesterol levels (p = 0.008), and total cholesterol/HDL cholesterol ratio (p = 0.048), compared to the noncarriers (AA), even after adjusting for potential confounders. Irrespective of obesity, the carriers of GG genotype had significantly lower fasting glucose levels with low saturated fatty acid intake (<7.3% of TE/day) (4.92 ± 0.1 mmol/L vs 5.80 ± 0.3 mmol/L, p = 0.011) and high intake of polyunsaturated fatty acid:saturated fatty acid ratio (≥0.8/day) (4.83 ± 0.1 mmol/ L vs 5.93 ± 0.4 mmol/L, p = 0.006). Moreover, the carriers of GG genotype with high polyunsaturated fatty acid intake (≥6% of TE/day) had significantly lower HOMA-IR (1.5 ± 0.3 vs 3.0 ± 0.7, p = 0.026) and fasting insulin levels (6.8 ± 1.6 µU/mL vs 11.4 ± 2.1 µU/mL, p = 0.036). *ese effects were not found in the noncarriers (AA). In conclusion, G allele carriers of ADRB2 rs1042713 were associated with increased odds of insulin resistance. Obese individuals carrying G allele were compromised with higher blood lipid levels. Although it is premature to report gene-diet interaction on the regulation of glucose and insulin levels in Malaysians, we suggest that higher quantity of PUFA-rich food sources in regular diet may benefit overweight and obese Malaysian adults metabolically. Large-scale studies are required to replicate and confirm the current findings in the Malaysian population

Assessment of friction between a rolling cylindrical element and a deformable flat surface

A cost-effective friction coefficient measuring technique was developed and tested. The technique involved the mounting of two sensing elements on the surface of rolls, in a manner that sought to measure simultaneously the normal and the tangential stresses during rolling. The instrumented roll termed “SGRoll” was segmented into two parts along the axial direction in order to position the sensing elements into the roll body. An experiment was run on a laboratory rolling mill equipment using 1100 aluminum as the work material. The experimental results showed that the friction coefficient decreased gradually as the workpiece entered the roll until no slip point and then decreased rapidly as the work piece exited the roll.Keywords: Friction, Force, Coefficient, SGRoll, Roll Angl

Les dynamiques de la végétation et des anthroposystèmes d’altitude cernées par l’anthracologie pastorale et minière à l’échelle d’un haut vallon alpestre (Freissinières, France)

This review paper outlines the reconstruction of vegetation and altitude anthroposystem dynamics, at the scale of the Freissinières high valley, based on the anthracological analysis of mining and (agro-) pastoral carbonised deposits, dating from the Bronze Age to the Renaissance. Archaeological and chronological features of the various deposit contexts, sampling protocol and laboratory methods used, have been outlined. All the obtained data has been summarized in diagrams, and attempts have been made to model vegetation dynamics and areas of firewood supply for mining and pastoral activities. Thus, this study identifies the major subalpine floristic changes that have occurred since the Bronze Age, the development of wood pasture and the lowering of the upper limit of dense forest associated with heathlands and thicket expansion. In addition, this study characterises the evolution of supply practices of fuel wood and the management of uncultivated area -particularly during the Middle Ages- and grasps the leaf-fodder cycle, documented by charcoals at the turn of the Modern era

Wavefield characteristics and spatial incoherency - a comparative study from Argostoli rock- and soil-site dense seismic arrays

International audienceThe current article presents the results from the analysis of the seismic events recorded from a dense array located on a rock site at Argostoli, Cephalonia Island, Greece. The objective of the study is to explore to what extent the non-direct, diffracted surface waves influence the seismic wavefield at a rock site, to investigate the loss of coherency of ground motions and to compare the results with those from a previously studied similar array located at an adjacent small, shallow sedimentary valley. The array consists of 21 velocimeters encompassing a central station in four concentric circles with diameters 20, 60, 180 and 360 m. The analyzed seismic dataset includes 40 events with magnitudes ranging from 2 to 5 and epicentral distance up to 200 km. MUSIQUE algorithm has been used to analyze the seismic wavefield by extracting the backazimuth and slowness of the dominant incoming waves and identifying the Love and Rayleigh waves. Lagged coherency has been estimated for all the available station pairs in the array and the results from the entire dataset have been averaged at four separation distance intervals, 10-20, 20-30, 30-40, 80-90 m. The results were also compared with those from a similar array located on an adjacent small, shallow sedimentary valley. The analysis suggests that about 20percent energy of the wavefield could be characterized as diffracted Love and Rayleigh waves, primarily arriving from the north-east and north-south directions, respectively. The spatial coherency estimations at the rock site are, generally, observed to be larger than those from the sedimentary array, especially at frequencies below 5 Hz. The directionality of coherency estimates observed from the soil array is absent in case of the rock array data. Comparison with the widely-quoted parametric models reveals that there is little correlation between the decay of coherency observed at the rock site and the models. The significant difference observed between the results of the rock and soil array indicate that the spatial incoherency is largely site dependent and could be potentially associated with the formation of locally generated wavefiel

Statistical properties of eigenstate amplitudes in complex quantum systems

We study the eigenstates of quantum systems with large Hilbert spaces, via their distribution of wavefunction amplitudes in a real-space basis. For single-particle 'quantum billiards', these real-space amplitudes are known to have Gaussian distribution for chaotic systems. In this work, we formulate and address the corresponding question for many-body lattice quantum systems. For integrable many-body systems, we examine the deviation from Gaussianity and provide evidence that the distribution generically tends toward power-law behavior in the limit of large sizes. We relate the deviation from Gaussianity to the entanglement content of many-body eigenstates. For integrable billiards, we find several cases where the distribution has power-law tails.Comment: revised version, with appendices; 15 pages, 10 figure

Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anti-Oxidative Activities

published_or_final_versio

Linking international clinical research with stateless populations to justice in global health

BACKGROUND: In response to calls to expand the scope of research ethics to address justice in global health, recent scholarship has sought to clarify how external research actors from high-income countries might discharge their obligation to reduce health disparities between and within countries. An ethical framework-'research for health justice'-was derived from a theory of justice (the health capability paradigm) and specifies how international clinical research might contribute to improved health and research capacity in host communities. This paper examines whether and how external funders, sponsors, and researchers can fulfill their obligations under the framework. METHODS: Case study research was undertaken on the Shoklo Malaria Research Unit's (SMRU) vivax malaria treatment trial, which was performed on the Thai-Myanmar border with Karen and Myanmar refugees and migrants. We conducted nineteen in-depth interviews with trial stakeholders, including investigators, trial participants, community advisory board members, and funder representatives; directly observed at trial sites over a five-week period; and collected trial-related documents for analysis. RESULTS: The vivax malaria treatment trial drew attention to contextual features that, when present, rendered the 'research for health justice' framework's guidance partially incomplete. These insights allowed us to extend the framework to consider external research actors' obligations to stateless populations. Data analysis then showed that framework requirements are largely fulfilled in relation to the vivax malaria treatment trial by Wellcome Trust (funder), Oxford University (sponsor), and investigators. At the same time, this study demonstrates that it may be difficult for long-term collaborations to shift the focus of their research agendas in accordance with the changing burden of illness in their host communities and to build the independent research capacity of host populations when working with refugees and migrants. Obstructive factors included the research funding environment and staff turnover due to resettlement or migration. CONCLUSIONS: Our findings show that obligations for selecting research targets, research capacity strengthening, and post-trial benefits that link clinical trials to justice in global health can be upheld by external research actors from high-income countries when working with stateless populations in LMICs. However, meeting certain framework requirements for long-term collaborations may not be entirely feasible