Embedding logical frameworks in scala

El Framework Lógico de Edimburgo ha demostrado ser una poderosa herramienta en el estudio formal de sistemas deductivos, como por ejemplo lenguajes de programación. Sin embargo su principal implementación, el sistema Twelf, carece de expresividad, obligando al programador a escribir código repetitivo. Este proyecto presenta una manera alternativa de utilizar Twelf: a través de un EDSL (Lenguaje Embebido de Dominio Específico) en Scala que permite representar firmas del Framework Lógico, y apoyándonos en Twelf como backend para la verificación, abrimos la puerta a diversas posibilidades en términos de metaprogramación. El código fuente, así como instrucciones para instalar y configurar, está accesible en https://github.com/akathorn/elfcala. ---ABSTRACT---The Edinburgh Logical Framework has proven to be to be a powerful tool in the formal study of deductive systems, such as programming languages. However, its main implementation, the Twelf system, lacks expressiveness, requiring the programmer to write repetitive code. This project presents an alternative way of using Twelf: by providing a Scala EDSL (Embedded Domain Specific Language) that can encode Logical Framework signatures and relying on Twelf as a backend for the verification, we open the door to different possibilities in terms of metaprogramming. The source code, along with instructions to install and configure, is accessible at https://github.com/akathorn/elfcal

An experimental right atrium platform to assess recirculation in hemodialysis catheters

Hemodialysis (HD) is a treatment supporting decreased kidney function, via a catheter inserted into the heart’s Right Atrium (RA). Recirculation is a source of inefficiency for treatment, where blood is dialysed again due to poor catheter design. Lab-testing is still relatively unexplored, hence, a mechanical testing system was designed with the intention of providing a consistent and repeatable environment for testing HD catheters. System geometry was composed using a Computer-Aided Design (CAD) model of a heart, with the RA scaled to appropriate dimensions, and a PolyDiMethylSiloxane (PDMS) model produced through 3D printing and negative wax casting. Pulsatile blood flow was mimicked by peristaltic pumps driving a blood analogue (BA). Recirculation was induced by adding dyed BA to the system via the catheter and measured using a colourimeter. The developed platform was initially evaluated using two catheters, demonstrating capability to accurately replicate atrial hemodynamic conditions. Two step-tipped catheters, A and B, were tested at 350 ml/min, producing recirculation values of 13.11% and 18.58%, respectively. The results exhibit the ability of the system developed to evaluate HD catheter performance, with potential to explore a wider range of tip geometries relevant to clinical preference. Furthermore, this advancement towards an anatomically accurate lab-based test system could be paired with computational methods to progress the evaluation of such medical devices and enhance their development

The Effect of Mechanical Overloading on Surface Roughness of the Coronary Arteries

Background. Surface roughness can be used to identify disease within biological tissues. Quantifying surface roughness in the coronary arteries aids in developing treatments for coronary heart disease. This study investigates the effect of extreme physiological loading on surface roughness, for example, due to a rupture of an artery. Methods. The porcine left anterior descending (LAD) coronary arteries were dissected ex vivo. Mechanical overloading was applied to the arteries in the longitudinal direction to simulate extreme physiological loading. Surface roughness was calculated from three-dimensional reconstructed images. Surface roughness was measured before and after damage and after chemical processing to dehydrate tissue specimens. Results. Control specimens confirmed that dehydration alone results in an increase of surface roughness in the circumferential direction only. No variation was noted between the hydrated healthy and damaged specimens, in both the longitudinal ( and ) and circumferential ( and ) directions. After dehydration, an increase in surface roughness was noted for damaged specimens in both the longitudinal () and circumferential () directions. Conclusions. Mechanical overloading applied in the longitudinal direction did not significantly affect surface roughness. However, when combined with chemical processing, a significant increase in surface roughness was noted in both the circumferential and longitudinal directions. Mechanical overloading causes damage to the internal constituents of the arteries, which is significantly noticeable after dehydration of tissue

Decision support model for the selection of asphalt wearing courses in highly trafficked roads

The suitable choice of the materials forming the wearing course of highly trafficked roads is a delicate task because of their direct interaction with vehicles. Furthermore, modern roads must be planned according to sustainable development goals, which is complex because some of these might be in conflict. Under this premise, this paper develops a multi-criteria decision support model based on the analytic hierarchy process and the technique for order of preference by similarity to ideal solution to facilitate the selection of wearing courses in European countries. Variables were modelled using either fuzzy logic or Monte Carlo methods, depending on their nature. The views of a panel of experts on the problem were collected and processed using the generalized reduced gradient algorithm and a distance-based aggregation approach. The results showed a clear preponderance by stone mastic asphalt over the remaining alternatives in different scenarios evaluated through sensitivity analysis. The research leading to these results was framed in the European FP7 Project DURABROADS (No. 605404).The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007–2013) under Grant Agreement No. 605404

Geographic Location System for Identifying Urban Road Sections Sensitive to Runoff Accumulation

ABSTRACT: This paper concerns the design of a geographic location system to identify urban road sections susceptible to runoff accumulation through the analysis of the efficiency of surface drainage networks. To this end, a combination of Geographic Information Systems (GISs) and stormwater models was proposed. First, GIS hydrology tools were employed to generate all the information required to characterise urban catchments geometrically. Then, a synthetic storm was created from precipitation data obtained through spatial interpolation for a given return period. Finally, the three main hydrological processes occurring in catchments (precipitation loss, transformation and routing) were simulated using the Hydrologic Modeling System (HEC-HMS). The system was tested through a case study of an urban catchment located in the city of Santander (Spain). The results demonstrate its usefulness in detecting critical points in terms of runoff accumulation, according to the efficiency of the existing surface drainage network

The urban heritage characterization using 3D geographic information systems. The system of medium-sized cities in Andalusia

The primary objective of this paper is to approach the use of the 3D Geographic Information Systems (3D GIS), as an instrumental tool that allows us to deal efficiently with the extensive amount of information that characterises a large part of the research carried out in the field of Urbanism and Regional Planning. Specifically, the study focuses on medium-sized cities in Andalusia, the most populous and the second largest region in Spain. The Andalusian urban system is substantially characterised by the historical importance of this type of cities within its territorial organisation, which dates back to more than two thousand years, and whose potential as sustainable and balanced stands out. In particular, it is intended to address features related to urban characterisation as medium-sized cities that have been declared as heritage sites, as well as, the integration of the cultural heritage into urban development planning as an active strategy by the cultural administration of the regional and local governments. In detail, this paper will analyse data relating to the development experienced, their characterisation through urban indicators or the evolution and traceability of their protection. In this sense, the use of 3D GIS will not only allow the efficient recording and the graphical representation of a significant amount of data resulting from the quantitative and qualitative analysis carried out but also model them using the third dimension to facilitate a cross analysis among the cities under study. Definitely, the aim is to demonstrate the suitability use of this technology in this type of scientific research.Ministry of Economy and Competitiveness of the Government of Spain HAR2016-79788-