Real Returns on Government Debt: A General Equilibrium Quantitative Exploration

We extend and apply computable general equilibrium methods to the study of economies with both aggregate uncertainty and uninsured household-specific uncertainty. In our economies the government issues two types of assets: a small denomination, non-interest bearing asset, which we call currency, and a large denomination, interest bearing asset, which we call T-bills. We find that a real interest rate behavior similar to that observed in the U.S. can be sustained as equilibrium behavior in our class of economies. We also find that policy induced real interest rate changes that are perceived as being permanent have significant real effects and that these effects take a few years to be fully realized.Publicad

The influence of Hickson-like compact group environment on galaxy luminosities

Compact groups of galaxies are devised as extreme environments where interactions may drive galaxy evolution. In this work, we analysed whether the luminosities of galaxies inhabiting compact groups differ from those of galaxies in loose galaxy groups. We computed the luminosity functions of galaxy populations inhabiting a new sample of 1412 Hickson-like compact groups of galaxies identified in the Sloan Digital Sky Survey Data Release 16. We observed a characteristic absolute magnitude for galaxies in compact groups brighter than that observed in the field or loose galaxy systems. We also observed a deficiency of faint galaxies in compact groups in comparison with loose systems. Our analysis showed that the brightening is mainly due to galaxies inhabiting the more massive compact groups. In contrast to what is observed in loose systems, where only the luminosities of Red (and Early) galaxies show a dependency with group mass, luminosities of Red and Blue (also Early and Late) galaxies in compact groups are affected similarly as a function of group virial mass. When using Hubble types, we observed that elliptical galaxies in compact groups are the brightest galaxy population, and groups dominated by an elliptical galaxy also display the brightest luminosities in comparison with those dominated by spiral galaxies. Moreover, we show that the general luminosity trends can be reproduced using a mock catalogue obtained from a semi-analytical model of galaxy formation. These results suggest that the inner extreme environment in compact groups prompts a different evolutionary history for their galaxies.Fil: Zandivarez, Arnaldo Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; ArgentinaFil: Díaz Giménez, E.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; ArgentinaFil: Taverna, Maria Antonela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; Argentin

Machine learning applied to the prediction of citrus production

An in-depth knowledge about variables affecting production is required in order to predict global production and take decisions in agriculture. Machine learning is a technique used in agricultural planning and precision agriculture. This work (i) studies the effectiveness of machine learning techniques for predicting orchards production; and (ii) variables affecting this production were also identified. Data from 964 orchards of lemon, mandarin, and orange in Corrientes, Argentina are analysed. Graphic and analytical descriptive statistics, correlation coefficients, principal component analysis and Biplot were performed. Production was predicted via M5-Prime, a model regression tree constructor which produces a classification based on piecewise linear functions. For all the species studied, the most informative variable was the trees’ age; in mandarin and orange orchards, age was followed by between and within row distances; irrigation also affected mandarin production. Also, the performance of M5-Prime in the prediction of production is adequate, as shown when measured with correlation coefficients (~0.8) and relative mean absolute error (~0.1). These results show that M5-Prime is an appropriate method to classify citrus orchards according to production and, in addition, it allows for identifying the most informative variables affecting production by tree

Fossil Groups in the Millennium Simulation. Evolution of the Brightest Galaxies

We create a catalogue of simulated fossil groups and study their properties, in particular the merging histories of their first-ranked galaxies. We compare the simulated fossil group properties with those of both simulated non-fossil and observed fossil groups. Using simulations and a mock galaxy catalogue, we searched for massive ($>$ 5 $\times$ 10$^{13} h^{-1} {\cal M}_\odot$) fossil groups in the Millennium Simulation Galaxy Catalogue. In addition, attempted to identify observed fossil groups in the Sloan Digital Sky Survey Data Release 6 using identical selection criteria. Our predictions on the basis of the simulation data are:(a) fossil groups comprise about 5.5% of the total population of groups/clusters with masses larger than 5 x 10$^{13} h^{-1} {\cal M}_\odot$. This fraction is consistent with the fraction of fossil groups identified in the SDSS, after all observational biases have been taken into account; (b) about 88% of the dominant central objects in fossil groups are elliptical galaxies that have a median R-band absolute magnitude of $\sim -23.5-5 log h$, which is typical of the observed fossil groups known in the literature; (c)first-ranked galaxies of systems with ${\cal M} >$ 5 x 10$^{13} h^{-1} {\cal M}_\odot$, regardless of whether they are either fossil or non-fossil, are mainly formed by gas-poor mergers; (d) although fossil groups, in general, assembled most of their virial masses at higher redshifts in comparison with non-fossil groups, first-ranked galaxies in fossil groups merged later, i.e. at lower redshifts, compared with their non-fossil-group counterparts. We therefore expect to observe a number of luminous galaxies in the centres of fossil groups that show signs of a recent major merger.Comment: 9 pages, 3 figures, accepted for publication in Astronomy & Astrophysic

Estrés parental y desarrollo infantil en niños prematuros

El presente trabajo trata de analizar si los niveles de estrés experimentados por los progenitores inciden sobre el desarrollo mental y motor de un grupo de niños nacidos demasiado pequeños o demasiado pronto. Participaron 19 niños y niñas nacidos, con menos de 36 semanas de gestación (media 29,84) y menos de 1500 gramos (media 1099,89), en el Hospital 12 de octubre de Madrid cuyos padres y madres consintieron participar en este trabajo. Los instrumentos utilizados fueron la Escala BSID-II para obtener los índices del desarrollo mental y psicomotor en los niños cuando alcanzaron la edad 2 años y la PSI de Abidin, para valorar el estrés total de los padres y madres participantes, así como su percepción de Malestar Paterno, Interacción Disfuncional y Niño Difícil. Los datos fueron sometidos a análisis de comparaciones de medias para muestras independientes. Los resultados indican que existen diferencias significativas entre los altos y los bajos niveles de estrés en cuanto a su incidencia en el desarrollo. En general, tanto en las madres como en los padres, cuando se obtiene una puntuación baja de estrés, existe un mejor desarrollo mental y psicomotor en los niños. Estos resultados se discuten a la luz de las investigaciones sobre el tema y se analizan las implicaciones para la elaboración de programas de atención temprana.The current document analyze if the parent’s stress levels influence the mental and motor development of a children’s group being born too young or too small. The participants were 19 preterm children born at the “Hospital 12 de Octubre” of Madrid with less than 36 gestation weeks (mean 29,84) and 1500 grammes (mean 1099,89), whose parents were agree to take part in this study. The employed instruments were the Bayley Scales of Infant Development (BSID-II) to obtain the mental and psychomotor index scores of the toddlers at 2 years old; and the Parenting Stress Index Short Form (PSI) of Abidin. to assess the Total Stress of the parents, and their perception of Parental Distress, Dysfunctional Parent-Child Interactions and Difficult Child also. The obtained data were analyzed comparing the means of two independent samples. The results show that there are significant differences in the children’s development depending of the high or low parental stress levels. In general terms, when parents have low levels of stress, a better mental and psychomotor development is observed in their children. These results are discussed in the light of other researches about the issue, being considered as well, their implications for the implementation of early intervention programs.peerReviewe

Geobotanical survey of Cabo Verde Islands (West Africa)

The results of the study of the bioclimate, biogeography, flora and vegetation of Cabo Verde Islands, after seven years of field works in all inhabited isles are presented in this paper. Tropical hyperdesertic to pluviseasonal, upper infra- to low supratropical and upper ultrahyperarid to upper dry, and occasionaly lower subhumid (short period years), are the bioclimates in these archipelago. Biogeographically they are situated in the Paleotropical Kingdom, Afrotropical Subkingdom, Tropical Saharan Region, and Cabo Verde Province. Eight new species are described: Acacia caboverdeana, Asphodelus mariolousae, Frankenia pseudoericifolia, Hyparrhenia caboverdeana, Lotus chevalieri, Polycarpaea caboverdeana, Suaeda caboverdeana and Tetraena vicentina, and also fifteen new combinations are proposed. In taxonomic phytosociology, five new classis: Cocculo penduli-Sarcostemmetea daltonii, Heteropogonetea contorti, Tetraenetea simplicis, Frankenio pseudoericifoliae-Suaedetea caboverdeanae and Arthrocnemetea franzii; nine new orders: Euphorbio tuckeyanae-Sarcostemmetalia daltonii, Dichrostachyo platycarpae-Acacietalia caboverdeanae, Melinio grandiflorae-Heteropogonetalia contorti, Aristido cardosoi-Tetraenetalia simplicis, Frankenio pseudoericifoliae-Suaedetalia caboverdeanae, Artrocnemetalia franzii, Sesuvietalia sesuvioidis, Kickxietalia elegantis and Euphorbietalia prostrato-hirtae; fourteen new alliances: Asparago squarrosi-Sarcostemmion daltonii, Globulario amygdalifoliae- Periplocion chevalieri, Fico gnaphalocarpae-Acacion caboverdeanae, Phoenicion atlanticae, Tamaricion senegalensis, Heteropogonion melanocarpo-contorti, Aristido cardosoi-Tetraenion simplicis, Polycarpaeo caboverdeanae-Tetraenion waterlotii, Arthrocnemion franzii, Sesuvion sesuvioidis, Adiantion trifidi, Kickxion elegantis, Adiantion incisophilippensis and Trianthemion portulacastri and, finally, fifty two new associations: Cocculo penduli-Sarcostemmetum daltonii, Campylantho spathulati-Sarcostemmetum daltonii, Frankenio caboverdeanae-Asparagetum squarrosi, Aeonio gogonei-Sarcostemmetum daltonii, Echio stenosiphonis-Euphorbietum tuckeyanae, Suaedo caboverdeanae-Asparagetum squarrosii, Tetraeno waterlotii-Sarcostemmetum daltonii, Erysimo caboverdeanae-Periplocetum chevalieri, Echietum vulcanori, Actinopterido radiatae-Sarcostemmetum daltonii, Echio hypertropici-Euphorbietum tuckeyanae, Launaeo thalassicae-Euphorbietum tuckeyanae, Loto latifolii-Artemisietum gogonei, Melanoselino bischoffii-Globularietum amygdalifoliae, Asterisco smithii-Euphorbietum tuckeyanae, Dichrostachyo platycarpae-Acacietum caboverdeanae, Cocculo penduli-Acacietum caboverdeanae, Forsskaoleo procridifoliae-Acacietum caboverdeanae, Cocculo penduli-Ficetum gnaphalocarpae, Forsskaoleo procridifoliae-Ficetum gnaphalocarpae, Dichrostachyo platycarpae-Ficetum sur, Euphorbio tuckeyanae-Ficetum sur, Sideroxyletum marginati, Dracaenetum caboverdeanae, Cocculo penduli-Phoenicetum atlanticae, Cocculo penduli-Tamaricetum senegalensis, Dichanthio foveolati-Heteropogonetum contorti, Heteropogonetum melanocarpi, Bothriochloo bladhii-Enneapogonetum desvauxii, Aristido cardosoi- Tetraenetum simplicis, Asphodelo mariolousae-Aristidetum cardosoi, Sehimatetum ischaemoidis, Polycarpaeo caboverdeanae-Tetraenetum waterlotii, Tetraenetum vicentinae, Sporobolo spicati-Cyperetum crassipedis, Loto brunneri- Pulicarietum diffusae, Arthrocnemetum franzii, Cressetum salinae, Sesuvietum sesuvioidis, Sesuvietum portulacastri, Blutaparonetum vermicularis, Adiantetum trifidi, Hypodematio crenati-Campanuletum bravensis, Kickxietum webbianae, Diplotaxio hirtae-Kickxietum elegantis, Umbilico schmidtii-Cheilanthetum acrosticae, Campanuletum jacobaeae, Campanulo bravensis-Launaetum thalassicae, Adiantetum inciso-philippensis, Trianthemetum portulacastri, Euphorbio hirtae-Boerhavietum repentis and Oldenlandietum corymbosae are proposed and describedinfo:eu-repo/semantics/publishedVersio

Interprofesionalidad y salud en el primer nivel de atención La experiencia en Barrio Penino, San José 2020

Este trabajo sistematiza y reflexiona acerca de la experiencia integral desarrollada en el primer nivel de atención en salud en el Barrio Penino, San José. Específicamente se expone la realizada en el año 2020 por un colectivo docente de seis servicios universitarios de la Universidad de la República, en la cual se formaron estudiantes de grado de esos centros, a través de varios proyectos que incluyeron la formación interprofesional como su eje central. En la práctica se actualizó la aproximación diagnóstica en salud realizada en 2019 prepandemia, destacando cambios y concordancias, y se realizaron una serie de actividades de promoción y educación para la salud bajo el lema #ConvivenciaSinViolencia. De ellas se destacan la implementación de la segunda edición de la Feria de la Salud, el diseño y realización de un mural y de una fotogalería, realizados en forma presencial en el segundo semestre de 2020. Durante la experiencia se priorizó la reflexión conjunta sobre temas relevantes, como la naturaleza del Sistema Nacional Integrado de Salud y sus fundamentos, la participación comunitaria en salud, la interdisciplina y la necesaria formación conjunta, tomando en cuenta las restricciones establecidas a partir de la emergencia sanitaria Los proyectos de intervención fueron diseñados e implementados por docentes y estudiantes

Selective targeting of human and animal pathogens of the helicobacter genus by flavodoxin inhibitors: Efficacy, synergy, resistance and mechanistic studies

Antimicrobial resistant (AMR) bacteria constitute a global health concern. Helicobacter py-lori is a Gram-negative bacterium that infects about half of the human population and is a major cause of peptic ulcer disease and gastric cancer. Increasing resistance to triple and quadruple H. pylori eradication therapies poses great challenges and urges the development of novel, ideally narrow spectrum, antimicrobials targeting H. pylori. Here, we describe the antimicrobial spectrum of a family of nitrobenzoxadiazol-based antimicrobials initially discovered as inhibitors of flavodoxin: an essential H. pylori protein. Two groups of inhibitors are described. One group is formed by nar-row-spectrum compounds, highly specific for H. pylori, but ineffective against enterohepatic Helico-bacter species and other Gram-negative or Gram-positive bacteria. The second group includes ex-tended-spectrum antimicrobials additionally targeting Gram-positive bacteria, the Gram-negative Campylobacter jejuni, and most Helicobacter species, but not affecting other Gram-negative pathogens. To identify the binding site of the inhibitors in the flavodoxin structure, several H. pylori-flavodoxin variants have been engineered and tested using isothermal titration calorimetry. An initial study of the inhibitors capacity to generate resistances and of their synergism with antimicrobials commonly used in H. pylori eradication therapies is described. The narrow-spectrum inhibitors, which are ex-pected to affect the microbiota less dramatically than current antimicrobial drugs, offer an oppor-tunity to develop new and specific H. pylori eradication combinations to deal with AMR in H. pylori. On the other hand, the extended-spectrum inhibitors constitute a new family of promising antimi-crobials, with a potential use against AMR Gram-positive bacterial pathogens. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

Cohesin Is Dispensable for Centromere Cohesion in Human Cells

BACKGROUND: Proper regulation of the cohesion at the centromeres of human chromosomes is essential for accurate genome transmission. Exactly how cohesion is maintained and is then dissolved in anaphase is not understood. PRINCIPAL FINDINGS: We have investigated the role of the cohesin complex at centromeres in human cells both by depleting cohesin subunits using RNA interference and also by expressing a non-cleavable version of the Rad21 cohesin protein. Rad21 depletion results in aberrant anaphase, during which the sister chromatids separate and segregate in an asynchronous fashion. However, centromere cohesion was maintained before anaphase in Rad21-depleted cells, and the primary constrictions at centromeres were indistinguishable from those in control cells. Expression of non-cleavable Rad21 (NC-Rad21), in which the sites normally cleaved by separase are mutated, resulted in delayed sister chromatid resolution in prophase and prometaphase, and a blockage of chromosome arm separation in anaphase, but did not impede centromere separation. CONCLUSIONS: These data indicate that cohesin complexes are dispensable for sister cohesion in early mitosis, yet play an important part in the fidelity of sister separation and segregation during anaphase. Cleavage at the separase-sensitive sites of Rad21 is important for arm separation, but not for centromere separation