Capacidades técnicas, legales y de gestión para equipos blueteam y redteam

Observación de la normativa y legislación referente a la seguridad de la información, código de ética, observación de un ejercicio aplicado, realización de pruebas de penetración, ataque, contención y neutralización de un ataque en un entorno controladoObserving the regulations and legislation regarding information security, code of ethics, observing an applied exercise, conducting penetration, attack, containment and neutralization tests of an attack in a controlled environmen

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting

Studying the interaction between charm and light-flavor mesons

International audienceThe two-particle momentum correlation functions between charm mesons ($\mathrm{D^{*\pm}}$ and $\mathrm{D}^\pm$) and charged light-flavor mesons ($\pi^{\pm}$ and K$^{\pm}$) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of $\sqrt{s} =13$ TeV. For $\mathrm{DK}$ and $\mathrm{D^*K}$ pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero

Studying the interaction between charm and light-flavor mesons

The two-particle momentum correlation functions between charm mesons ($\mathrm{D^{*\pm}}$ and $\mathrm{D}^\pm$) and charged light-flavor mesons ($\pi^{\pm}$ and K$^{\pm}$) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of $\sqrt{s} =13$ TeV. For $\mathrm{DK}$ and $\mathrm{D^*}\mathrm{K}$ pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ pairs, a tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero.The two-particle momentum correlation functions between charm mesons ($\mathrm{D^{*\pm}}$ and $\mathrm{D}^\pm$) and charged light-flavor mesons ($\pi^{\pm}$ and K$^{\pm}$) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of $\sqrt{s} =13$ TeV. For $\mathrm{DK}$ and $\mathrm{D^*K}$ pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero

Measurement of beauty-quark production in pp collisions at s=13\sqrt{s}=13 TeV via non-prompt D mesons

International audienceThe $p_{\rm T}$-differential production cross sections of non-prompt ${\rm D^0}$, ${\rm D^+}$, and ${\rm D_s^+}$ mesons originating from beauty-hadron decays are measured in proton$-$proton collisions at a centre-of-mass energy $\sqrt{s}$ of 13 TeV. The measurements are performed at midrapidity, $|y| < 0.5$, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, $f_{\rm{s}}/(f_{\rm{u}} + f_{\rm{d}})$, is found to be $0.114 \pm 0.016~{\rm (stat.)} \pm 0.006~{\rm (syst.)} \pm 0.003~{\rm (BR)} \pm 0.003~{\rm (extrap.)}$. This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at $\sqrt{s} = 5.02$ and 13 TeV, showing a hardening of the non-prompt D-meson $p_{\rm T}$-differential production cross section at higher $\sqrt{s}$. Finally, the ${\rm b\overline{b}}$ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt ${\rm D^0}$, ${\rm D^+}$, ${\rm D_s^+}$, and $\Lambda_{\rm c}^+$ hadron measurements, obtaining ${\rm d}\sigma/{\rm d}y = 75.2\pm 3.2~(\mathrm{stat.}) \pm 5.2~(\mathrm{syst.})^{+12.3}_{-3.2} ~(\mathrm{extrap.})\text{ } \rm \mu b \;.

Measurement of beauty-quark production in pp collisions at s=13\sqrt{s}=13 TeV via non-prompt D mesons

International audienceThe $p_{\rm T}$-differential production cross sections of non-prompt ${\rm D^0}$, ${\rm D^+}$, and ${\rm D_s^+}$ mesons originating from beauty-hadron decays are measured in proton$-$proton collisions at a centre-of-mass energy $\sqrt{s}$ of 13 TeV. The measurements are performed at midrapidity, $|y| < 0.5$, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, $f_{\rm{s}}/(f_{\rm{u}} + f_{\rm{d}})$, is found to be $0.114 \pm 0.016~{\rm (stat.)} \pm 0.006~{\rm (syst.)} \pm 0.003~{\rm (BR)} \pm 0.003~{\rm (extrap.)}$. This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at $\sqrt{s} = 5.02$ and 13 TeV, showing a hardening of the non-prompt D-meson $p_{\rm T}$-differential production cross section at higher $\sqrt{s}$. Finally, the ${\rm b\overline{b}}$ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt ${\rm D^0}$, ${\rm D^+}$, ${\rm D_s^+}$, and $\Lambda_{\rm c}^+$ hadron measurements, obtaining ${\rm d}\sigma/{\rm d}y = 75.2\pm 3.2~(\mathrm{stat.}) \pm 5.2~(\mathrm{syst.})^{+12.3}_{-3.2} ~(\mathrm{extrap.})\text{ } \rm \mu b \;.

Measurement of beauty-quark production in pp collisions at s=13\mathbf{\sqrt{\textit{s}}=13} TeV via non-prompt D mesons

The $p_{\rm T}$-differential production cross sections of non-prompt D$^{0}$, D$^{+}$, and D$^{+}_{\rm s}$ mesons originating from beauty-hadron decays are measured in proton--proton collisions at a centre-of-mass energy $\sqrt{s}$ of 13 TeV. The measurements are performed at midrapidity, $|y| < 0.5$, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, $f_{\rm s}/(f_{\rm u}+f_{\rm d})$, is found to be $0.114 \pm 0.016~{\rm (stat.)} \pm 0.006~{\rm (syst.)} \pm 0.003~{\rm (BR)} \pm 0.003~{\rm (extrap.)}$. This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at $\sqrt{s} = 5.02$ and 13 TeV, showing a hardening of the non-prompt D-meson $p_{\rm T}$-differential production cross section at higher $\sqrt{s}$. Finally, the ${\rm b\overline{b}}$ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt D$^{0}$, D$^{+}$, D$^{+}_{\rm s}$, and $\Lambda_{\rm c}^{+}$ hadron measurements, obtaining ${\rm d}\sigma/{\rm d}y = 75.2\pm 3.2~(\mathrm{stat.}) \pm 5.2~(\mathrm{syst.})^{+12.3}_{-3.2} ~(\mathrm{extrap.})\text{ } \rm \mu b$.The $p_{\rm T}$-differential production cross sections of non-prompt ${\rm D^0}$, ${\rm D^+}$, and ${\rm D_s^+}$ mesons originating from beauty-hadron decays are measured in proton$-$proton collisions at a centre-of-mass energy $\sqrt{s}$ of 13 TeV. The measurements are performed at midrapidity, $|y| < 0.5$, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, $f_{\rm{s}}/(f_{\rm{u}} + f_{\rm{d}})$, is found to be $0.114 \pm 0.016~{\rm (stat.)} \pm 0.006~{\rm (syst.)} \pm 0.003~{\rm (BR)} \pm 0.003~{\rm (extrap.)}$. This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at $\sqrt{s} = 5.02$ and 13 TeV, showing a hardening of the non-prompt D-meson $p_{\rm T}$-differential production cross section at higher $\sqrt{s}$. Finally, the ${\rm b\overline{b}}$ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt ${\rm D^0}$, ${\rm D^+}$, ${\rm D_s^+}$, and $\Lambda_{\rm c}^+$ hadron measurements, obtaining ${\rm d}\sigma/{\rm d}y = 75.2\pm 3.2~(\mathrm{stat.}) \pm 5.2~(\mathrm{syst.})^{+12.3}_{-3.2} ~(\mathrm{extrap.})\text{ } \rm \mu b \;.

Measurement of beauty-quark production in pp collisions at s=13\sqrt{s}=13 TeV via non-prompt D mesons

International audienceThe $p_{\rm T}$-differential production cross sections of non-prompt ${\rm D^0}$, ${\rm D^+}$, and ${\rm D_s^+}$ mesons originating from beauty-hadron decays are measured in proton$-$proton collisions at a centre-of-mass energy $\sqrt{s}$ of 13 TeV. The measurements are performed at midrapidity, $|y| < 0.5$, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calculations. The fragmentation fraction of beauty quarks to strange mesons divided by the one to non-strange mesons, $f_{\rm{s}}/(f_{\rm{u}} + f_{\rm{d}})$, is found to be $0.114 \pm 0.016~{\rm (stat.)} \pm 0.006~{\rm (syst.)} \pm 0.003~{\rm (BR)} \pm 0.003~{\rm (extrap.)}$. This value is compatible with previous measurements at lower centre-of-mass energies and in different collision systems in agreement with the assumption of universality of fragmentation functions. In addition, the dependence of the non-prompt D meson production on the centre-of-mass energy is investigated by comparing the results obtained at $\sqrt{s} = 5.02$ and 13 TeV, showing a hardening of the non-prompt D-meson $p_{\rm T}$-differential production cross section at higher $\sqrt{s}$. Finally, the ${\rm b\overline{b}}$ production cross section per unit of rapidity at midrapidity is calculated from the non-prompt ${\rm D^0}$, ${\rm D^+}$, ${\rm D_s^+}$, and $\Lambda_{\rm c}^+$ hadron measurements, obtaining ${\rm d}\sigma/{\rm d}y = 75.2\pm 3.2~(\mathrm{stat.}) \pm 5.2~(\mathrm{syst.})^{+12.3}_{-3.2} ~(\mathrm{extrap.})\text{ } \rm \mu b \;.

Studying the interaction between charm and light-flavor mesons

International audienceThe two-particle momentum correlation functions between charm mesons ($\mathrm{D^{*\pm}}$ and $\mathrm{D}^\pm$) and charged light-flavor mesons ($\pi^{\pm}$ and K$^{\pm}$) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of $\sqrt{s} =13$ TeV. For $\mathrm{DK}$ and $\mathrm{D^*K}$ pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero

Studying the interaction between charm and light-flavor mesons

International audienceThe two-particle momentum correlation functions between charm mesons ($\mathrm{D^{*\pm}}$ and $\mathrm{D}^\pm$) and charged light-flavor mesons ($\pi^{\pm}$ and K$^{\pm}$) in all charge-combinations are measured for the first time by the ALICE Collaboration in high-multiplicity proton-proton collisions at a center-of-mass energy of $\sqrt{s} =13$ TeV. For $\mathrm{DK}$ and $\mathrm{D^*K}$ pairs, the experimental results are in agreement with theoretical predictions of the residual strong interaction based on quantum chromodynamics calculations on the lattice and chiral effective field theory. In the case of $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ pairs, tension between the calculations including strong interactions and the measurement is observed. For all particle pairs, the data can be adequately described by Coulomb interaction only, indicating a shallow interaction between charm and light-flavor mesons. Finally, the scattering lengths governing the residual strong interaction of the $\mathrm{D}\pi$ and $\mathrm{D^*}\pi$ systems are determined by fitting the experimental correlation functions with a model that employs a Gaussian potential. The extracted values are small and compatible with zero