963 research outputs found
Mortality risk and mental disorders: longitudinal results from the Upper Bavarian Study
The object of the study was the assessment of the mortality risk for persons with a mental disorder in an unselected representative community sample assessed longitudinally. Subjects from a rural area in Upper Bavaria (Germany) participated in semi-structured interviews conducted by research physicians in the 1970s (first assessment) and death-certificate diagnoses were obtained after an interval up to 13 years later. The sample consisted of 1668 community residents aged 15 years and over. Cox regression estimates resulted in an odds ratio of 1·35 (confidence interval 1·01 to 1·81) for persons with a mental disorder classified as marked to very severe. The odds ratio increased with increasing severity of mental illness from 1·04 for mild disorders, 1·30 for marked disorders, to 1·64 for severe or very severe disorders. The relative risk (odds ratio) for persons with a mental disorder only and no somatic disorder was 1·22, for persons with only a somatic disorder 2·00, and for those with both a mental and a somatic disorder 2·13. The presence of somatic illness was responsible for most of the excess mortality. Somatic disorders associated with excess mortality in mental disorders were diseases of the nervous system or sensory organs, diseases of the circulatory system, diseases of the gastrointestinal tract, and diseases of the skeleton, muscles and connective tissue (ICD-8). Thus, while mental illness alone had a limited effect on excess mortality, comorbidity with certain somatic disorders had a significant effec
First direct mass-measurement of the two-neutron halo nucleus 6He and improved mass for the four-neutron halo 8He
The first direct mass-measurement of He has been performed with the
TITAN Penning trap mass spectrometer at the ISAC facility. In addition, the
mass of He was determined with improved precision over our previous
measurement. The obtained masses are (He) = 6.018 885 883(57) u and
(He) = 8.033 934 44(11) u. The He value shows a deviation from
the literature of 4. With these new mass values and the previously
measured atomic isotope shifts we obtain charge radii of 2.060(8) fm and
1.959(16) fm for He and He respectively. We present a detailed
comparison to nuclear theory for He, including new hyperspherical harmonics
results. A correlation plot of the point-proton radius with the two-neutron
separation energy demonstrates clearly the importance of three-nucleon forces.Comment: 4 pages, 2 figure
Highly charged ions in Penning traps, a new tool for resolving low lying isomeric states
The use of highly charged ions increases the precision and resolving power,
in particular for short-lived species produced at on-line radio-isotope beam
facilities, achievable with Penning trap mass spectrometers. This increase in
resolving power provides a new and unique access to resolving low-lying
long-lived ( ms) nuclear isomers. Recently, the keV
(determined from -ray spectroscopy) isomeric state in Rb has
been resolved from the ground state, in a charge state of with the TITAN
Penning trap at the TRIUMF-ISAC facility. The excitation energy of the isomer
was measured to be keV above the ground state. The extracted
masses for both the ground and isomeric states, and their difference, agree
with the AME2003 and Nuclear Data Sheet values. This proof of principle
measurement demonstrates the feasibility of using Penning trap mass
spectrometers coupled to charge breeders to study nuclear isomers and opens a
new route for isomer searches.Comment: 8 pages, 6 figure
First Penning-trap mass measurement in the millisecond half-life range: the exotic halo nucleus 11Li
In this letter, we report a new mass for Li using the trapping
experiment TITAN at TRIUMF's ISAC facility. This is by far the shortest-lived
nuclide, , for which a mass measurement has ever been
performed with a Penning trap. Combined with our mass measurements of
Li we derive a new two-neutron separation energy of 369.15(65) keV: a
factor of seven more precise than the best previous value. This new value is a
critical ingredient for the determination of the halo charge radius from
isotope-shift measurements. We also report results from state-of-the-art
atomic-physics calculations using the new mass and extract a new charge radius
for Li. This result is a remarkable confluence of nuclear and atomic
physics.Comment: Formatted for submission to PR
Low-Background In-Trap Decay Spectroscopy with TITAN at TRIUMF
An in-trap decay spectroscopy setup has been developed and constructed for
use with the TITAN facility at TRIUMF. The goal of this device is to observe
weak electron-capture (EC) branching ratios for the odd-odd intermediate nuclei
in the decay process. This apparatus consists of an up-to 6 Tesla,
open-access spectroscopy ion-trap, surrounded radially by up to 7 planar Si(Li)
detectors which are separated from the trap by thin Be windows. This
configuration provides a significant increase in sensitivity for the detection
of low-energy photons by providing backing-free ion storage and eliminating
charged-particle-induced backgrounds. An intense electron beam is also employed
to increase the charge-states of the trapped ions, thus providing storage times
on the order of minutes, allowing for decay-spectroscopy measurements. The
technique of multiple ion-bunch stacking was also recently demonstrated, which
further extends the measurement possibilities of this apparatus. The current
status of the facility and initial results from a In measurement are
presented.Comment: Proceedings for the 2nd International Conference on Advances in
Radioactive Isotope Science (ARIS2014
Variability of Image Features Computed from Conventional and Respiratory-Gated PET/CT Images of Lung Cancer
AbstractRadiomics is being explored for potential applications in radiation therapy. How various imaging protocols affect quantitative image features is currently a highly active area of research. To assess the variability of image features derived from conventional [three-dimensional (3D)] and respiratory-gated (RG) positron emission tomography (PET)/computed tomography (CT) images of lung cancer patients, image features were computed from 23 lung cancer patients. Both protocols for each patient were acquired during the same imaging session. PET tumor volumes were segmented using an adaptive technique which accounted for background. CT tumor volumes were delineated with a commercial segmentation tool. Using RG PET images, the tumor center of mass motion, length, and rotation were calculated. Fifty-six image features were extracted from all images consisting of shape descriptors, first-order features, and second-order texture features. Overall, 26.6% and 26.2% of total features demonstrated less than 5% difference between 3D and RG protocols for CT and PET, respectively. Between 10 RG phases in PET, 53.4% of features demonstrated percent differences less than 5%. The features with least variability for PET were sphericity, spherical disproportion, entropy (first and second order), sum entropy, information measure of correlation 2, Short Run Emphasis (SRE), Long Run Emphasis (LRE), and Run Percentage (RPC); and those for CT were minimum intensity, mean intensity, Root Mean Square (RMS), Short Run Emphasis (SRE), and RPC. Quantitative analysis using a 3D acquisition versus RG acquisition (to reduce the effects of motion) provided notably different image feature values. This study suggests that the variability between 3D and RG features is mainly due to the impact of respiratory motion
Breakdown of the Isobaric Multiplet Mass Equation for the A = 20 and 21 Multiplets
Using the Penning trap mass spectrometer TITAN, we performed the first direct
mass measurements of 20,21Mg, isotopes that are the most proton-rich members of
the A = 20 and A = 21 isospin multiplets. These measurements were possible
through the use of a unique ion-guide laser ion source, a development that
suppressed isobaric contamination by six orders of magnitude. Compared to the
latest atomic mass evaluation, we find that the mass of 21Mg is in good
agreement but that the mass of 20Mg deviates by 3{\sigma}. These measurements
reduce the uncertainties in the masses of 20,21Mg by 15 and 22 times,
respectively, resulting in a significant departure from the expected behavior
of the isobaric multiplet mass equation in both the A = 20 and A = 21
multiplets. This presents a challenge to shell model calculations using either
the isospin non-conserving USDA/B Hamiltonians or isospin non-conserving
interactions based on chiral two- and three-nucleon forces.Comment: 5 pages, 2 figure
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