2,502 research outputs found
A Status Report Lockheed Launch Vehicle
This paper discusses a new family of small and medium space launch vehicles being developed by Lockheed Missiles & Space Company, Inc. The development program will culminate in a demonstration launch in November 1994. The paper gives a brief background and gives the program status as of the date of this paper. Supporting graphics are included
Exploring potential germline associated roles of the TRIM-NHL protein NHL-2 through RNAi screening
TRIM-NHL proteins are highly conserved regulators of developmental pathways in vertebrates and invertebrates. The TRIM-NHL family member NHL-2 in Caenorhabditis elegans functions as a miRNA cofactor to regulate developmental timing. Similar regulatory roles have been reported in other model systems, with the mammalian ortholog in mice, TRIM32, contributing to muscle and neuronal cell proliferation via miRNA activity. Given the interest associated with TRIM-NHL family proteins, we aimed to further investigate the role of NHL-2 in C. elegans development by using a synthetic RNAi screening approach. Using the ORFeome library, we knocked down 11,942 genes in wild-type animals and nhl-2 null mutants. In total, we identified 42 genes that produced strong reproductive synthetic phenotypes when knocked down in nhl-2 null mutants, with little or no change when knocked down in wild-type animals. These included genes associated with transcriptional processes, chromosomal integrity, and key cofactors of the germline small 22G RNA pathway.Gregory M. Davis, Wai Y. Low, Joshua W.T. Anderson and Peter R. Boa
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Volumes, Masses, and Surface Areas for Shippingport LWBR Spent Nuclear Fuel in a DOE SNF Canister
The purpose of this calculation is to estimate volumes, masses, and surface areas associated with (a) an empty Department of Energy (DOE) 18-inch diameter, 15-ft long spent nuclear fuel (SNF) canister, (b) an empty DOE 24-inch diameter, 15-ft long SNF canister, (c) Shippingport Light Water Breeder Reactor (LWBR) SNF, and (d) the internal basket structure for the 18-in. canister that has been designed specifically to accommodate Seed fuel from the Shippingport LWBR. Estimates of volumes, masses, and surface areas are needed as input to structural, thermal, geochemical, nuclear criticality, and radiation shielding calculations to ensure the viability of the proposed disposal configuration
3D seismic imaging of buried Younger Dryas mass movement flows: Lake Windermere, UK
Windermere is a glacially overdeepened lake located in the southeastern Lake District, UK. Using the threedimensional(3D) Chirp subbottom profiler, we image mass movement deposits related to the Younger Dryas(YD) within a decimetre-resolution 3D seismic volume, documenting their internal structure and interactionwith preexisting deposits in unprecedented detail. Three distinct flow events are identified and mappedthroughout the 3D survey area. Package structures and seismic attributes classify them as: a small (totalvolume of c. 1500 m3) debris flow containing deformed translated blocks; a large (inferred total volume ofc. 500,000 m3), homogeneous fine-grained mass flow deposit; and a debris flow (inferred total volume ofc. 60,000 m3) containing small (c. 8.0×2.0 m) deformed translated blocks. Geomorphological mapping oftheir distribution and interaction with preexisting sediments permit the reconstruction of a depositionalhistory for the stratigraphic units identified in the seismic volume.<br/
The maximal energy of classes of integral circulant graphs
The energy of a graph is the sum of the moduli of the eigenvalues of its
adjacency matrix. We study the energy of integral circulant graphs, also called
gcd graphs, which can be characterized by their vertex count and a set
of divisors of in such a way that they have vertex set
and edge set . For a fixed prime power and a fixed divisor set size , we analyze the maximal energy among all matching integral circulant
graphs. Let be the elements of .
It turns out that the differences between the exponents of
an energy maximal divisor set must satisfy certain balance conditions: (i)
either all equal , or at most the two differences
and may occur; %(for a certain depending on and ) (ii)
there are rules governing the sequence of consecutive
differences. For particular choices of and these conditions already
guarantee maximal energy and its value can be computed explicitly.Comment: Discrete Applied Mathematics (2012
Decision-analysis modelling of the effects of thromboprophylaxis for people with lower limb immobilisation for injury.
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Thermo-Oxidation of Tokamak Carbon Dust
The oxidation of dust and flakes collected from the DIII-D tokamak, and various commercial dust specimens, has been measured at 350 ºC and 2.0 kPa O2 pressure. Following an initial small mass loss, most of the commercial dust specimens showed very little effect due to O2 exposure. Similarly, dust collected from underneath DIII-D tiles, which is thought to comprise largely Grafoil™ particulates, also showed little susceptibility to oxidation at this temperature. However, oxidation of the dust collected from tile surfaces has led to ~ 18% mass loss after 8 hours; thereafter, little change in mass was observed. This suggests that the surface dust includes some components of different composition and/or structure – possibly fragments of codeposited layers. The oxidation of codeposit flakes scraped form DIII-D upper divertor tiles showed an initial 25% loss in mass due to heating in vacuum, and the gradual loss of 30-38% mass during the subsequent 24 hours exposure to O2. This behavior is significantly different from that observed for the oxidation of thinner DIII-D codeposit specimens which were still adhered to tile surfaces, and this is thought to be related to the low deuterium content (D/C ~ 0.03 – 0.04) of the flakes
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