1,484 research outputs found
Erratum to: Evolving hard problems: generating human genetics datasets with a complex etiology
In situ evidence for the structure of the magnetic null in a 3D reconnection event in the Earth's magnetotail
Magnetic reconnection is one of the most important processes in
astrophysical, space and laboratory plasmas. Identifying the structure around
the point at which the magnetic field lines break and subsequently reform,
known as the magnetic null point, is crucial to improving our understanding
reconnection. But owing to the inherently three-dimensional nature of this
process, magnetic nulls are only detectable through measurements obtained
simultaneously from at least four points in space. Using data collected by the
four spacecraft of the Cluster constellation as they traversed a diffusion
region in the Earth's magnetotail on 15 September, 2001, we report here the
first in situ evidence for the structure of an isolated magnetic null. The
results indicate that it has a positive-spiral structure whose spatial extent
is of the same order as the local ion inertial length scale, suggesting that
the Hall effect could play an important role in 3D reconnection dynamics.Comment: 14 pages, 4 figure
Gauge Fluxes in F-theory and Type IIB Orientifolds
We provide a detailed correspondence between G_4 gauge fluxes in F-theory
compactifications with SU(n) and SU(n)x(1) gauge symmetry and their Type IIB
orientifold limit. Based on the resolution of the relevant F-theory Tate models
we classify the factorisable G_4-fluxes and match them with the set of
universal D5-tadpole free U(1)-fluxes in Type IIB. Where available, the global
version of the universal spectral cover flux corresponds to Type IIB gauge flux
associated with a massive diagonal U(1). In U(1)-restricted Tate models extra
massless abelian fluxes exist which are associated with specific linear
combinations of Type IIB fluxes. Key to a quantitative match between F-theory
and Type IIB is a proper treatment of the conifold singularity encountered in
the Sen limit of generic F-theory models. We also shed further light on the
brane recombination process relating generic and U(1)-restricted Tate models.Comment: 53 pages, 3 figures; v2: Refs added; v3: minor corrections to match
version published in JHE
Observation of an Efimov spectrum in an atomic system
In 1970 V. Efimov predicted a puzzling quantum-mechanical effect that is
still of great interest today. He found that three particles subjected to a
resonant pairwise interaction can join into an infinite number of loosely bound
states even though each particle pair cannot bind. Interestingly, the
properties of these aggregates, such as the peculiar geometric scaling of their
energy spectrum, are universal, i.e. independent of the microscopic details of
their components. Despite an extensive search in many different physical
systems, including atoms, molecules and nuclei, the characteristic spectrum of
Efimov trimer states still eludes observation. Here we report on the discovery
of two bound trimer states of potassium atoms very close to the Efimov
scenario, which we reveal by studying three-particle collisions in an ultracold
gas. Our observation provides the first evidence of an Efimov spectrum and
allows a direct test of its scaling behaviour, shedding new light onto the
physics of few-body systems.Comment: 10 pages, 3 figures, 1 tabl
Eliciting a predatory response in the eastern corn snake (Pantherophis guttatus) using live and inanimate sensory stimuli: implications for managing invasive populations
North America's Eastern corn snake (Pantherophis guttatus) has been introduced to several islands throughout the Caribbean and Australasia where it poses a significant threat to native wildlife. Invasive snake control programs often involve trapping with live bait, a practice that, as well as being costly and labour intensive, raises welfare and ethical concerns. This study assessed corn snake response to live and inanimate sensory stimuli in an attempt to inform possible future trapping of the species and the development of alternative trap lures. We exposed nine individuals to sensory cues in the form of odour, visual, vibration and combined stimuli and measured the response (rate of tongue-flick [RTF]). RTF was significantly higher in odour and combined cues treatments, and there was no significant difference in RTF between live and inanimate cues during odour treatments. Our findings suggest chemical cues are of primary importance in initiating predation and that an inanimate odour stimulus, absent of simultaneous visual and vibratory cues, is a potential low-cost alternative trap lure for the control of invasive corn snake populations
Family Planning Decisions, Perceptions and Gender Dynamics among Couples in Mwanza, Tanzania: A Qualitative Study.
Contraceptive use is low in developing countries which are still largely driven by male dominated culture and patriarchal values. This study explored family planning (FP) decisions, perceptions and gender dynamics among couples in Mwanza region of Tanzania. Twelve focus group discussions and six in-depth interviews were used to collect information from married or cohabiting males and females aged 18-49. The participants were purposively selected. Qualitative methods were used to explore family planning decisions, perceptions and gender dynamics among couples. A guide with questions related to family planning perceptions, decisions and gender dynamics was used. The discussions and interviews were tape-recorded, transcribed verbatim and analyzed manually and subjected to content analysis. Four themes emerged during the study. First, "risks and costs" which refer to the side effects of FP methods and the treatment of side -effects as well as the costs inherit in being labeled as an unfaithful spouse. Second, "male involvement" as men showed little interest in participating in family planning issues. However, the same men were mentioned as key decision-makers even on the number of children a couple should have and the child spacing of these children. Third, "gender relations and communication" as participants indicated that few women participated in decision-making on family planning and the number of children to have. Fourth, "urban-rural differences", life in rural favoring having more children than urban areas therefore, the value of children depended on the place of residence. Family Planning programs should adapt the promotion of communication as well as joint decision-making on FP among couples as a strategy aimed at enhancing FP use
Linear Sigma Models with Torsion
Gauged linear sigma models with (0,2) supersymmetry allow a larger choice of
couplings than models with (2,2) supersymmetry. We use this freedom to find a
fully linear construction of torsional heterotic compactifications, including
models with branes. As a non-compact example, we describe a family of metrics
which correspond to deformations of the heterotic conifold by turning on
H-flux. We then describe compact models which are gauge-invariant only at the
quantum level. Our construction gives a generalization of symplectic reduction.
The resulting spaces are non-Kahler analogues of familiar toric spaces like
complex projective space. Perturbatively conformal models can be constructed by
considering intersections.Comment: 40 pages, LaTeX, 1 figure; references added; a new section on
supersymmetry added; quantization condition revisite
The role of Comprehension in Requirements and Implications for Use Case Descriptions
Within requirements engineering it is generally accepted that in writing specifications (or indeed any requirements phase document), one attempts to produce an artefact which will be simple to comprehend for the user. That is, whether the document is intended for customers to validate requirements, or engineers to understand what the design must deliver, comprehension is an important goal for the author. Indeed, advice on producing ‘readable’ or ‘understandable’ documents is often included in courses on requirements engineering. However, few researchers, particularly within the software engineering domain, have attempted either to define or to understand the nature of comprehension and it’s implications for guidance on the production of quality requirements.
Therefore, this paper examines thoroughly the nature of textual comprehension, drawing heavily from research in discourse process, and suggests some implications for requirements (and other) software documentation. In essence, we find that the guidance on writing requirements, often prevalent within software engineering, may be based upon assumptions which are an oversimplification of the nature of comprehension. Hence, the paper examines guidelines which have been proposed, in this case for use case descriptions, and the extent to which they agree with discourse process theory; before suggesting refinements to the guidelines which attempt to utilise lessons learned from our richer understanding of the underlying discourse process theory. For example, we suggest subtly different sets of writing guidelines for the different tasks of requirements, specification and design
F-theory on Genus-One Fibrations
We argue that M-theory compactified on an arbitrary genus-one fibration, that
is, an elliptic fibration which need not have a section, always has an F-theory
limit when the area of the genus-one fiber approaches zero. Such genus-one
fibrations can be easily constructed as toric hypersurfaces, and various
and models are presented as examples. To each
genus-one fibration one can associate a -function on the base as well as
an representation which together define the IIB axio-dilaton
and 7-brane content of the theory. The set of genus-one fibrations with the
same -function and representation, known as the
Tate-Shafarevich group, supplies an important degree of freedom in the
corresponding F-theory model which has not been studied carefully until now.
Six-dimensional anomaly cancellation as well as Witten's zero-mode count on
wrapped branes both imply corrections to the usual F-theory dictionary for some
of these models. In particular, neutral hypermultiplets which are localized at
codimension-two fibers can arise. (All previous known examples of localized
hypermultiplets were charged under the gauge group of the theory.) Finally, in
the absence of a section some novel monodromies of Kodaira fibers are allowed
which lead to new breaking patterns of non-Abelian gauge groups.Comment: 53 pages, 9 figures, 6 tables. v2: references adde
Prenatal hypoxia induces increased cardiac contractility on a background of decreased capillary density.
Background: Chronic hypoxia in utero (CHU) is one of the most common insults to fetal development and may be associated with poor cardiac recovery from ischaemia-reperfusion injury,yet the effects on normal cardiac mechanical performance are poorly understood.
Methods: Pregnant female wistar rats were exposed to hypoxia (12% oxygen, balance nitrogen)for days 10–20 of pregnancy. Pups were born into normal room air and weaned normally. At 10 weeks of age, hearts were excised under anaesthesia and underwent retrograde 'Langendorff' perfusion. Mechanical performance was measured at constant filling pressure (100 cm H2O) with intraventricular balloon. Left ventricular free wall was dissected away and capillary density estimated following alkaline phosphatase staining. Expression of SERCA2a and Nitric Oxide Synthases (NOS) proteins were estimated by immunoblotting.
Results: CHU significantly increased body mass (P < 0.001) compared with age-matched control rats but was without effect on relative cardiac mass. For incremental increases in left ventricular balloon volume, diastolic pressure was preserved. However, systolic pressure was significantly greater following CHU for balloon volume = 50 μl (P < 0.01) and up to 200 μl (P < 0.05). For higher balloon volumes systolic pressure was not significantly different from control. Developed pressures were correspondingly increased relative to controls for balloon volumes up to 250 μl (P < 0.05).Left ventricular free wall capillary density was significantly decreased in both epicardium (18%; P <0.05) and endocardium (11%; P < 0.05) despite preserved coronary flow. Western blot analysis revealed no change to the expression of SERCA2a or nNOS but immuno-detectable eNOS protein was significantly decreased (P < 0.001) in cardiac tissue following chronic hypoxia in utero.
Conclusion: These data offer potential mechanisms for poor recovery following ischaemia, including decreased coronary flow reserve and impaired angiogenesis with subsequent detrimental effects of post-natal cardiac performance
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