6,857 research outputs found
Boundary Controllability and Observability of a Viscoelastic String
In this paper we consider an integrodifferential system, which governs the vibration of a viscoelastic one-dimensional object. We assume that we can act on the system at the boundary and we prove that it is possible to control both the position and the velocity at every point of the body and at a certain time , large enough. We shall prove this result using moment theory and we shall prove that the solution of this problem leads to identify a Riesz sequence which solves controllability and observability. So, the result as presented here are constructive and can lead to simple numerical algorithms
Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML
HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may be related to AML, we investigated the HTIF1α DNA structure and RNA expression in leukemic cells from 36 M1–M5 AML patients (28 ‘de novo’ and eight ‘secondary’ to myelodysplastic syndrome (MDS)). Abnormal HTIF1α DNA fragments were never found, whereas loss of HTIF1α DNA was observed in the patients with chromosome 7q32 deletion and translocation, and in one case without detectable chromosome 7 abnormality. HTIF1α RNA was found in acute myelocytic leukemic blasts, and was almost undetectable in normal mononuclear cells. The expression varied among the patients: higher in M1 to M3 subtypes, with the highest values in M1; low levels were constantly observed in M4 and M5 AML. In addition, HTIF1α was significantly overexpressed in MDS-related AML (MDR-AML), but not in MDS. We also found that HTIF1α expression was high in myeloid cell lines. In myeloblastic HL60 and promyelocytic NB4 cells, induced to differentiate along the monocytic–macrophage pathway by TPA or vitamin D3, HTIF1α expression decreased, whereas it was maintained at high levels on induction to granulocytic differentiation by RA or DMSO. In K562 cells, HTIF1α RNA levels did not change after hemin-induced erythroid differentiation. These results suggest that HTIF1α could play a role in myeloid differentiation, being distinctly regulated in hematopoietic lineages
AlpStore Project: A Viable Model for Renewables Exploitation in the Alps
AbstractNowadays, the integration of intermittent and unpredictable Renewable Energy Sources (RESs) has led to new issues for the electrical system. The paper proposes a model, named Virtual Power System (VPS), which enables the management of generators and loads as a single (virtual) entity in order to achieve a “global” benefit, i.e. to improve the capability of the grid to host RESs. Moreover Energy Storage Systems (ESSs) could be integrated in the VPS in order to provide ancillary services: voltage regulation, primary frequency regulation and exchange profiles adjustment for a better RESs programmability. This work proposes a quantitative approach for ESSs design and integration in a VPS. Numerical results are reported with respect to an experimental application in the AlpStore project (Alpine Space Program 2007-2013)
Proof-of-principle of a new geometry for sampling calorimetry using inorganic scintillator plates
A novel geometry for a sampling calorimeter employing inorganic scintillators
as an active medium is presented. To overcome the mechanical challenges of
construction, an innovative light collection geometry has been pioneered, that
minimises the complexity of construction. First test results are presented,
demonstrating a successful signal extraction. The geometry consists of a
sampling calorimeter with passive absorber layers interleaved with layers of an
active medium made of inorganic scintillating crystals. Wavelength-shifting
(WLS) fibres run along the four long, chamfered edges of the stack,
transporting the light to photodetectors at the rear. To maximise the amount of
scintillation light reaching the WLS fibres, the scintillator chamfers are
depolished. It is shown herein that this concept is working for cerium fluoride
(CeF) as a scintillator. Coupled to it, several different types of
materials have been tested as WLS medium. In particular, materials that might
be sufficiently resistant to the High-Luminosity Large Hadron Collider
radiation environment, such as cerium-doped Lutetium-Yttrium Orthosilicate
(LYSO) and cerium-doped quartz, are compared to conventional plastic WLS
fibres. Finally, an outlook is presented on the possible optimisation of the
different components, and the construction and commissioning of a full
calorimeter cell prototype is presented.Comment: Submitted to Proceedings CALOR 2014, the 16th International
Conference on Calorimetry in High-Energy Physics, Giessen (Germany) 6 - 11
April 2014. To be published in Journal of Physics: Conference Series (10
pages, 15 figures
Experimental Validation of the Attenuation Properties in the Sonic Range of Metaconcrete Containing Two Types of Resonant Inclusions
Background: Metaconcrete is a new concept of concrete, showing marked attenuation properties under impact and blast loading, where traditional aggregates are partially replaced by resonant bi-material inclusions. In a departure from conventional mechanical metamaterials, the inclusions are dispersed randomly as cast in the material. The behavior of metaconcrete at supersonic frequencies has been investigated theoretically and numerically and confirmed experimentally.
Objective: The feasibility of metaconcrete to achieve wave attenuation at low frequencies demands further experimental validation. The present study is directed at characterizing dynamically, in the range of the low sonic frequencies, the—possibly synergistic—effect of combinations of different types of inclusions on the attenuation properties of metaconcrete.
Methods: Dynamic tests are conducted on cylindrical metaconcrete specimens cast with two types of spherical inclusions, made of a steel core and a polymeric coating. The two inclusions differ in terms of size and coating material: type 1 inclusions are 22 mm diameter with 1.35 mm PDMS coating; type 2 inclusions are 24 mm diameter with 2 mm layer natural rubber coating. Linear frequency sweeps in the low sonic range (< 10 kHz), tuned to numerically estimated inclusion eigenfrequencies, are applied to the specimens through a mechanical actuator. The transmitted waves are recorded by transducers and Fast-Fourier transformed (FFT) to bring the attenuation spectrum of the material into full display.
Results: Amplitude reductions of transmitted signals are markedly visible for any metaconcrete specimens in the range of the inclusion resonant frequencies, namely, 3,400-3,500 Hz for the PDMS coating inclusions and near 3,200 Hz for the natural rubber coating inclusions. Specimens with mixed inclusions provide a rather uniform attenuation in a limited range of frequencies, independently of the inclusion density, while specimens with a single inclusion type are effective over larger frequency ranges. With respect to conventional concrete, metaconcrete reduces up to 90% the amplitude of the transmitted signal within the attenuation bands.
Conclusions: Relative to conventional concrete, metaconcrete strongly attenuates waves over frequency bands determined by the resonant frequencies of the inclusions. The present dynamical tests conducted in the sonic range of frequencies quantify the attenuation properties of the metaconcrete cast with two types inclusions, providing location, range and intensity of the attenuation bands, which are dependent on the physical-geometric features of the inclusions
Extrafloral-nectar based partner manipulation in plant-ant relationship
Plant–ant interactions are generally considered as mutualisms, with both parties gaining benefits from
the association. It has recently emerged that some of these mutualistic associations have, however, evolved towards
other forms of relationships and, in particular, that plants may manipulate their partner ants to make reciprocation
more beneficial, thereby stabilizing the mutualism. Focusing on plants bearing extrafloral nectaries, we review recent
studies and address three key questions: (i) how can plants attract potential partners and maintain their services;
(ii) are there compounds in extrafloral nectar that could mediate partner manipulation; and (iii) are ants susceptible
to such compounds? After reviewing the current knowledge on plant–ant associations, we propose a possible scenario
where plant-derived chemicals, such as secondary metabolites, known to have an impact on animal brain, could
have evolved in plants to attract and manipulate ant behaviour. This new viewpoint would place plant–animal interaction
in a different ecological context, opening new ecological and neurobiological perspectives of drug seeking
and use
Avaliação de genitoras sexuais de Brachiaria ssp. Na época de seca.
Atualmente o Brasil é o maior produtor e exportador de sementes forrageiras tropicais da América Latina em que as demandas por qualidade e quantidade de sementes vêm impulsionando toda a cadeia produtiva. Com este trabalho objetivou-se avaliar populações híbridas interespecíficas sexuais visando a selecionar genitoras para colaborar na diversificação de pastagens tropicais cultivadas do gênero Brachiaria. O experimento foi realizado na Embrapa Gado de Corte em Campo Grande-MS, no período de janeiro a agosto de 2013. Foi realizado teste de progênies de meio irmãos, visando à seleção entre e dentro de famílias, sendo selecionados os melhores genitores com base na progênie e, também, os melhores indivíduos dentro das progênies.O delineamento experimental foi em blocos ao acaso, com dez repetições e parcelas com cinco plantas, avaliadas individualmente para produção de massa seca total e foliar, porcentagem de lâminas foliares, relação lâmina foliar:pseudocolmo e capacidade de rebrota. Adotando-se a intensidade de seleção de 1% dos híbridos selecionados, 100% são produtos do cruzamento das melhores progenitoras, com ganhos de seleção variando de 11,07% a 30,39%. Estes resultados permitem afirmar que é possível fazer a seleção dos melhores indivíduos com ganhos expressivos ao programa de melhoramento
A series of new conjugated oligothiophenes for organic electronics
Thiophene oligomers and polymers can be found in a huge number of materials with applications in the field of Organic Electronics. Chemical and electrochemical syntheses along with electrochemical studies and complete characterization of a series of new conjugated oligothiophene derivatives are reported. Two different molecular architectures, D-A (donor-acceptor) and A-D-A (acceptor-donor-acceptor), were taken into account. The results from voltammetric experiments and optical studies confirm the close relationship between the structure of these compounds and their electrochemical behaviour. This series of oligothiophenes shows low bandgaps, a mandatory requirement for their use in Organic Electronics, and, clearly, they are promising candidates for future synthetic studies in order to modify their optical and electrochemical properties to achieve better performances as organic semiconductors
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