18 research outputs found
Elucidating the Mechanisms Surrounding H2A.X Monoubiquitylation Marks in the DNA Damage Response Pathway
- Author
- Publication venue
- Publication date
- 05/03/2019
- Field of study
In response to DNA double-strand breaks (DSBs), H2A.X undergoes three post-translational modifications (PTMs) reported to be important for DSB signaling: phosphorylation at serine 139, monoubiquitylation at lysines 118/119 and monoubiquitylation at lysines 13/15. We aimed to gain a better understanding of the mechanisms surrounding H2A.X monoubiquitylation marks and their relationship to H2A.X phosphorylation. We have developed and tested a novel purification method for the isolation of ubiquitylated H2A.X-containing nucleosomes, which can be used to co-purify DNA damage-response proteins that interact with ubiquitylated H2A.X-containing nucleosomes. Our data show that monoubiquitylation of lysines 118/119 is not required for phosphorylation at serine 139, nor for monoubiquitylation at lysines 13/15 in cis (on the same H2A.X molecule). Our data also suggests that monoubiquitylation of lysines 118/119 may have an antagonistic effect on monoubiquitylation of lysines 13/15. Lastly, we saw that different DSB-inducing agents can have different effects on H2A.X monoubiquitylation
Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star
- Author
- Abac Adrian
- Abbott R.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aghaei Abchouyeh Maryam
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akcay Sarp
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi Simone
- Alex iandolo Guido
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés Vallejo Peña Sergio
- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
- Ansoldi Stefano
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- Zhong Haowen
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- Árpád Gergely László
- 劉 國欽
- 都丸 隆行
- Publication venue
- Publication date
- 23/04/2024
- Field of study
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Arif Shaikh Md
- Aritomi Naoki
- Arnaud Nicolas
- Arogeti M.
- Aronson S. M.
- Arène M.
- Asada Hideki
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- Babak Stanislav
- Badaracco Francesca
- Badger C.
- Bae S.
- Bae Y.
- Bagnasco Stefano
- Bai Y.
- Baier J. G.
- Baird J.
- Bajpai Rishabh
- Baka T.
- Ball M.
- Ballardin G.
- Ballmer S. W.
- Baltus Grégory
- Banagiri Sharan
- Banerjee Biswajit
- Bankar Deepak
- Barayoga J. C.
- Barish B. C.
- Barker D.
- Barneo Pablo
- Barone Fabrizio
- Barr Bryan
- Barsotti Lisa
- Barsuglia Matteo
- Barta Dániel
- Bartlett J.
- Barton Mark Andrew
- Bartos I.
- Basak S.
- Bassiri Riccardo
- Basti A.
- Bawaj Mateusz
- Bayley Joseph
- Bazzan M.
- Beatrice Cummings Rebecca
- Bedakihale V. M.
- Beirnaert Freija
- Bejger Michał
- Belahcene I.
- Bell Angus
- Benedetto V.
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- Benoit William
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- Bernuzzi Sebastiano
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- Berry Christopher P. L.
- Bersanetti Diego
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- Beveridge Damon
- Bhandare R.
- Bhandari A. V.
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- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
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- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adamcewicz C.
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Almualla M.
- Altin Paul
- Amato Alex
- Amez-Droz L.
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- Anand S.
- Ananyeva A.
- Andersen R.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
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- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
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- Antier Sarah
- Antonio Font Roda Jose
- Aoumi M.
- Apostolatos T.
- Appavuravther E. Z.
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- Aronson Scott
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- Toriyama A.
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- Vahlbruch Henning
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- Wysocki Daniel
- Xiao Liting
- Xu Victoria
- Yaala M. Ben
- Yadav Nikesh
- Yakovlev Alexey
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
- Yamamoto M.
- Yamamoto Takahiro
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- Yamamura S.
- Yamazaki Ryo
- Yan S.
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- Yang Y. -C.
- Yang Yang
- Yang Yi
- Yap M. J.
- Yarbrough Zach
- Yeh S. -W.
- Yelikar A. B.
- Yeung S. M. C.
- Yeung T. Y.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuzurihara Hirotaka
- Zadrożny A.
- Zahoor Jan Aasim
- Zannelli A. J.
- Zanolin M.
- Zeeshan M.
- Zelenova T.
- Zendri J. -P.
- Zevin Michael
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Ya
- Zhang Yanqi
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Álvarez-López S.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/08/2023
- Field of study
Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level
Ultralight vector dark matter search using data from the KAGRA O3GK run
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adamcewicz Christian
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
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- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
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- de rossi camilla
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- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM
The Effectiveness of Exercise for the Management of Musculoskeletal Disorders and Injuries of the Elbow, Forearm, Wrist, and Hand: A Systematic Review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration
- Author
- Abrams
- America Academy of Orthopaedic Surgeons
- Anne Taylor-Vaisey
- Atroshi
- Bardak
- Bisset
- Buckle
- Carroll
- Carroll
- Cohen
- Courtney Brown
- Craig Jacobs
- Cullinane
- Côté
- Dale
- Danielle Southerst
- Deborah Sutton
- Follmann
- Franchignoni
- Gail M. Lindsay
- Hainan Yu
- Harbour
- Hayden
- Hayden
- Heather M. Shearer
- Jessica J. Wong
- Jocelyn Cox
- Kevin D'Angelo
- Kristi Randhawa
- Kurppa
- Maja Stupar
- Martinez-Silvestrini
- McGowan
- Moher
- Moher
- Moher
- Morrison
- Page
- Palmer
- Pedersen
- Peterson
- Peterson
- Piazzini
- Pierre Côté
- Plancher
- Prevention CfDCa
- Ranney
- Roger Menta
- Sampson
- Sarah Dion
- Sharanya Varatharajan
- Shiri
- Silvano Mior
- Slavin
- Smidt
- Spitzer
- Stasinopoulos
- Sutton
- Tashjian
- Than
- Trudel
- van der Velde
- Watson
- Werner
- Workplace Safety & Insurance Board
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Stress Echocardiography in Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging
- Author
- Abbate Massimiliana
- Accadia Maria
- Alemanni Rossella
- Angelini Andrea
- Anglano Francesco
- Anselmi Maurizio
- Antonini-Canterin Francesco
- Aquila Iolanda
- Aramu Simona
- Avogadri Enrico
- Azzaro Giuseppe
- Badano Luigi
- Balducci Anna
- Ballocca Flavia
- Barbarossa Alessandro
- Barbati Giovanni
- Barbieri Andrea
- Barchitta Agata
- Barletta Valentina
- Barone Daniele
- Becherini Francesco
- Benfari Giovanni
- Beraldi Monica
- Bergandi Gianluigi
- Bilardo Giuseppe
- Binno Simone Maurizio
- Bolognesi Massimo
- Bongiovi Stefano
- Bragato Renato Maria
- Braggion Gabriele
- Brancaleoni Rossella
- Bursi Francesca
- Cameli Matteo
- Canu Antonella
- Capitelli Mariano
- Capra Anna Clara Maria
- Carbonara Rosa
- Carbone Maria
- Carbonella Marco
- Carerj Scipione
- Carrabba Nazario
- Casavecchia Grazia
- Casula Margherita
- Chesi Elena
- Ciampi Quirino
- Cicco Sebastiano
- Citro Rodolfo
- Cocchia Rosangela
- Colombo Barbara Maria
- Colonna Paolo
- Conte Maddalena
- Corrado Giovanni
- Cortesi Pietro
- Cortigiani Lauro
- Costantino Marco Fabio
- Cozza Fabiana
- Cucchini Umberto
- D'Andrea Antonello
- D'Andrea Fabrizio
- D'Angelo Myriam
- D'Auria Francesca
- Da Ros Santina
- De Caridi Giovanni
- De Feo Stefania
- De Matteis Giovanni Maria
- De Vecchi Simona
- Del Giudice Carmen
- Dell'Angela Luca
- Dentamaro Ilaria
- Dessalvi Christian Cadeddu
- Destefanis Paola
- Di Bella Gianluca
- Di Fulvio Maria
- Di Gaetano Renato
- Di Giannuario Giovanna
- Di Gioia Angelo
- Di Muro Carmine
- Di Nora Concetta
- Di Salvo Giovanni
- Dodi Claudio
- Dogliani Sarah
- Donati Federica
- Dottori Melissa
- Epifani Giuseppe
- Fabiani Iacopo
- Faganello Giorgio
- Ferrara Francesca
- Ferrara Luigi
- Ferrua Stefania
- Filice Gemma
- Fiorino Maria
- Forno Davide
- Garini Alberto
- Giarratana Gioachino Agostino
- Gigantino Giuseppe
- Giorgi Mauro
- Giubertoni Elisa
- Greco Cosimo Angelo
- Grigolato Michele
- Holzl Anna
- Iaiza Alessandra
- Iannaccone Andrea
- Ilardi Federica
- Imbalzano Egidio
- Inciardi Riccardo M.
- Inserra Corinna Antonia
- Iori Emilio
- Izzo Annibale
- La Rosa Giuseppe
- Labanti Graziana
- Lanzone Alberto Maria
- Lanzoni Laura
- Lapetina Ornella
- Leiballi Elisa
- Librera Mariateresa
- Lo Conte Carmenita
- Lo Monaco Maria
- Lombardo Antonella
- Luciani Michelangelo
- Lusardi Paola
- Magnante Antonio
- Malagoli Alessandro
- Malatesta Gelsomina
- Mancusi Costantino
- Manes Maria Teresa
- Manganelli Fiore
- Mantovani Francesca
- Manuppelli Vincenzo
- Marchese Valeria
- Marinacci Lina
- Marra Walter Grosso
- Massimiliano Di Martino Luigi Flavio
- Mattioli Roberto
- Maurizio Civelli
- Mazza Giuseppe Antonio
- Mazza Stefano
- Melis Marco
- Meloni Giulia
- Merli Elisa
- Miceli Sofia
- Milan Alberto
- Minardi Giovanni
- Monaco Antonella
- Monte Ines
- Montresor Graziano
- Moreo Antonella
- Mori Fabio
- Morini Sofia
- Moro Claudio
- Morrone Doralisa
- Negri Francesco
- Nipote Carmelo
- Nisi Fulvio
- Nocco Silvio
- Novello Luigi
- Nunziata Luigi
- Paoli Lucrezia Delli
- Parato Vito Maurizio
- Parodi Antonello
- Pasanisi Emilio Maria
- Pastorini Guido
- Pavasini Rita
- Pavoni Daisy
- Pedone Chiara
- Pelliccia Francesco
- Pelliciari Giovanni
- Pelloni Elisa
- Pepi Mauro
- Pergola Valeria
- Perillo Giovanni
- Perini Alessandro Paoletti
- Petruccelli Enrica
- Pezzullo Chiara
- Piacentini Gerardo
- Picano Eugenio
- Picardi Elisa
- Pinna Giovanni
- Pizzarelli Massimiliano
- Pizzuti Alfredo
- Poggi Matteo Maria
- Posteraro Alfredo
- Privitera Carmen
- Rampazzo Debora
- Ratti Carlo
- Rettegno Sara
- Ricci Caterina
- Ricci Fabrizio
- Rolando Cristina
- Rossi Stefania
- Rovera Chiara
- Ruggieri Roberta
- Russo Maria Giovanna
- Sacchi Nicola
- Saladino Antonino
- Sani Francesca
- Sartori Chiara
- Scarabeo Virginia
- Sciacqua Angela
- Scillone Antonio
- Scopelliti Pasquale Antonio
- Scorza Alfredo
- Scozzafava Angela
- Serafini Francesco
- Serra Walter
- Severino Sergio
- Simeone Beatrice
- Sirico Domenico
- Solari Marco
- Spadaro Gian Luca
- Stefani Laura
- Strangio Antonio
- Surace Francesca Chiara
- Tamborini Gloria
- Tarquinio Nicola
- Tassone Eliezer Joseph
- Tavarozzi Isabella
- Tchana Bertrand
- Tedesco Giuseppe
- Tinto Monica
- Torzillo Daniela
- Tota Antonio
- Totaro Antonio
- Triolo Oreste Fabio
- Trocino Giuseppe
- Troisi Federica
- Tusa Maurizio
- Vancheri Federico
- Varasano Vincenzo
- Venezia Amedeo
- Vermi Anna Chiara
- Villari Bruno
- Zampi Giordano
- Zannoni Jessica
- Zito Concetta
- Zugaro Antonello
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: The Italian Society of Echography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand the volumes of activity, modalities and stressors used during stress echocardiography (SE) in Italy. Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved through an electronic survey based on a structured questionnaire, uploaded on the SIECVI website. Results: Data were obtained from 228 echocardiographic laboratories, and SE examinations were performed in 179 centers (80.6%): 87 centers (47.5%) were in the northern regions of Italy, 33 centers (18.4%) were in the central regions, and 61 (34.1%) in the southern regions. We annotated a total of 4057 SE. We divided the SE centers into three groups, according to the numbers of SE performed: <10 SE (low-volume activity, 40 centers), between 10 and 39 SE (moderate volume activity, 102 centers) and >= 40 SE (high volume activity, 37 centers). Dipyridamole was used in 139 centers (77.6%); exercise in 120 centers (67.0%); dobutamine in 153 centers (85.4%); pacing in 37 centers (21.1%); and adenosine in 7 centers (4.0%). We found a significant difference between the stressors used and volume of activity of the centers, with a progressive increase in the prevalence of number of stressors from low to high volume activity (P = 0.033). The traditional evaluation of regional wall motion of the left ventricle was performed in all centers, with combined assessment of coronary flow velocity reserve (CFVR) in 90 centers (50.3%): there was a significant difference in the centers with different volume of SE activity: the incidence of analysis of CFVR was significantly higher in high volume centers compared to low - moderate - volume (32.5%, 41.0% and 73.0%, respectively, P < 0.001). The lung ultrasound (LUS) was assessed in 67 centers (37.4%). Furthermore for LUS, we found a significant difference in the centers with different volume of SE activity: significantly higher in high volume centers compared to low - moderate - volume (25.0%, 35.3% and 56.8%, respectively, P < 0.001). Conclusions: This nationwide survey demonstrated that SE was significantly widespread and practiced throughout Italy. In addition to the traditional indication to coronary artery disease based on regional wall motion analysis, other indications are emerging with an increase in the use of LUS and CFVR, especially in high-volume centers
Organization and Activity of Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging
- Author
- Abbate Massimiliana
- Accadia Maria
- Alemanni Rossella
- Angelini Andrea
- Anglano Francesco
- Anselmi Maurizio
- Antonini-Canterin Francesco
- Aquila Iolanda
- Aramu Simona
- Avogadri Enrico
- Azzaro Giuseppe
- Badano Luigi
- Balducci Anna
- Ballocca Flavia
- Barbarossa Alessandro
- Barbati Giovanni
- Barbieri Andrea
- Barchitta Agata
- Barletta Valentina
- Barone Daniele
- Becherini Francesco
- Benfari Giovanni
- Beraldi Monica
- Bergandi Gianluigi
- Bilardo Giuseppe
- Binno Simone Maurizio
- Bolognesi Massimo
- Bongiovi Stefano
- Bragato Renato Maria
- Braggion Gabriele
- Brancaleoni Rossella
- Bursi Francesca
- Cameli Matteo
- Canu Antonella
- Capitelli Mariano
- Capra Anna Clara Maria
- Carbonara Rosa
- Carbone Maria
- Carbonella Marco
- Carerj Scipione
- Carrabba Nazario
- Casavecchia Grazia
- Casula Margherita
- Chesi Elena
- Ciampi Quirino
- Cicco Sebastiano
- Citro Rodolfo
- Cocchia Rosangela
- Colombo Barbara Maria
- Colonna Paolo
- Conte Carmenita Lo
- Conte Maddalena
- Corrado Giovanni
- Cortesi Pietro
- Cortigiani Lauro
- Costantino Marco Fabio
- Cozza Fabiana
- Cucchini Umberto
- D'Andrea Antonello
- D'Andrea Fabrizio
- D'Angelo Myriam
- D'Auria Francesca
- De Caridi Giovanni
- De Feo Stefania
- De Matteis Giovanni Maria
- De Vecchi Simona
- Dell'Angela Luca
- Dentamaro Ilaria
- Dessalvi Christian Cadeddu
- Destefanis Paola
- Di Bella Gianluca
- Di Fulvio Maria
- Di Gaetano Renato
- Di Giannuario Giovanna
- Di Gioia Angelo
- Di Martino Luigi Flavio Massimiliano
- Di Muro Carmine
- Di Nora Concetta
- Di Salvo Giovanni
- Dodi Claudio
- Dogliani Sarah
- Donati Federica
- Dottori Melissa
- Epifani Giuseppe
- Fabiani Iacopo
- Faganello Giorgio
- Ferrara Francesca
- Ferrara Luigi
- Ferrua Stefania
- Filice Gemma
- Fiorino Maria
- Forno Davide
- Garini Alberto
- Giarratana Gioachino Agostino
- Gigantino Giuseppe
- Giorgi Mauro
- Giubertoni Elisa
- Giudice Carmen Del
- Greco Cosimo Angelo
- Grigolato Michele
- Holzl Anna
- Iaiza Alessandra
- Iannaccone Andrea
- Ilardi Federica
- Imbalzano Egidio
- Inciardi Riccardo
- Inserra Corinna Antonia
- Iori Emilio
- Izzo Annibale
- Labanti Graziana
- Lanzone Alberto Maria
- Lanzoni Laura
- Lapetina Ornella
- Leiballi Elisa
- Librera Mariateresa
- Lombardo Antonella
- Luciani Michelangelo
- Lusardi Paola
- Magnante Antonio
- Malagoli Alessandro
- Malatesta Gelsomina
- Mancusi Costantino
- Manes Maria Teresa
- Manganelli Fiore
- Mantovani Francesca
- Manuppelli Vincenzo
- Marchese Valeria
- Marinacci Lina
- Marra Walter Grosso
- Mattioli Roberto
- Maurizio Civelli
- Mazza Giuseppe Antonio
- Mazza Stefano
- Melis Marco
- Meloni Giulia
- Merli Elisa
- Miceli Sofia
- Milan Alberto
- Minardi Giovanni
- Monaco Antonella
- Monaco Maria Lo
- Monte Ines
- Montresor Graziano
- Moreo Antonella
- Mori Fabio
- Morini Sofia
- Moro Claudio
- Morrone Doralisa
- Negri Francesco
- Nipote Carmelo
- Nisi Fulvio
- Nocco Silvio
- Novello Luigi
- Nunziata Luigi
- Paoli Lucrezia Delli
- Parato Vito Maurizio
- Parodi Antonello
- Pasanisi Emilio Maria
- Pastorini Guido
- Pavasini Rita
- Pavoni Daisy
- Pedone Chiara
- Pelliccia Francesco
- Pelliciari Giovanni
- Pelloni Elisa
- Pepi Mauro
- Pergola Valeria
- Perillo Giovanni
- Perini Alessandro Paoletti
- Petruccelli Enrica
- Pezzullo Chiara
- Piacentini Gerardo
- Picardi Elisa
- Pinna Giovanni
- Pizzarelli Massimiliano
- Pizzuti Alfredo
- Poggi Matteo Maria
- Posteraro Alfredo
- Privitera Carmen
- Rampazzo Debora
- Ratti Carlo
- Rettegno Sara
- Ricci Caterina
- Ricci Fabrizio
- Rolando Cristina
- Ros Santina Da
- Rosa Giuseppe La
- Rossi Stefania
- Rovera Chiara
- Ruggieri Roberta
- Russo Maria Giovanna
- Sacchi Nicola
- Saladino Antonino
- Sani Francesca
- Sartori Chiara
- Scarabeo Virginia
- Sciacqua Angela
- Scillone Antonio
- Scopelliti Pasquale Antonio
- Scorza Alfredo
- Scozzafava Angela
- Serafini Francesco
- Serra Walter
- Severino Sergio
- Simeone Beatrice
- Sirico Domenico
- Solari Marco
- Spadaro Gian Luca
- Stefani Laura
- Strangio Antonio
- Surace Francesca Chiara
- Tamborini Gloria
- Tarquinio Nicola
- Tassone Eliezer Joseph
- Tavarozzi Isabella
- Tchana Bertrand
- Tedesco Giuseppe
- Tinto Monica
- Torzillo Daniela
- Tota Antonio
- Totaro Antonio
- Triolo Oreste Fabio
- Trocino Giuseppe
- Troisi Federica
- Tusa Maurizio
- Vancheri Federico
- Varasano Vincenzo
- Venezia Amedeo
- Vermi Anna Chiara
- Villari Bruno
- Zampi Giordano
- Zannoni Jessica
- Zito Concetta
- Zugaro Antonello
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: The Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand better how different echocardiographic modalities are used and accessed in Italy. Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved via an electronic survey based on a structured questionnaire, uploaded on the SIECVI website. Results: Data were obtained from 228 echocardiographic laboratories: 112 centers (49%) in the northern, 43 centers (19%) in the central, and 73 (32%) in the southern regions. During the month of observation, we collected 101,050 transthoracic echocardiography (TTE) examinations performed in all centers. As concern other modalities there were performed 5497 transesophageal echocardiography (TEE) examinations in 161/228 centers (71%); 4057 stress echocardiography (SE) examinations in 179/228 centers (79%); and examinations with ultrasound contrast agents (UCAs) in 151/228 centers (66%). We did not find significant regional variations between the different modalities. The usage of picture archiving and communication system (PACS) was significantly higher in the northern (84%) versus central (49%) and southern (45%) centers (P < 0.001). Lung ultrasound (LUS) was performed in 154 centers (66%), without difference between cardiology and noncardiology centers. The evaluation of left ventricular (LV) ejection fraction was evaluated mainly using the qualitative method in 223 centers (94%), occasionally with the Simpson method in 193 centers (85%), and with selective use of the three-dimensional (3D) method in only 23 centers (10%). 3D TTE was present in 137 centers (70%), and 3D TEE in all centers where TEE was done (71%). The assessment of LV diastolic function was done routinely in 80% of the centers. Right ventricular function was evaluated using tricuspid annular plane systolic excursion in all centers, using tricuspid valve annular systolic velocity by tissue Doppler imaging in 53% of the centers, and using fractional area change in 33% of the centers. When we divided into cardiology (179, 78%) and noncardiology (49, 22%) centers, we found significant differences in the SE (93% vs. 26%, P < 0.001), TEE (85% vs. 18%), UCA (67% vs. 43%, P < 0001), and STE (87% vs. 20%, P < 0.001). The incidence of LUS evaluation was similar between the cardiology and noncardiology centers (69% vs. 61%, P = NS). Conclusions: This nationwide survey demonstrated that digital infrastructures and advanced echocardiography modalities, such as 3D and STE, are widely available in Italy with a notable diffuse uptake of LUS in the core TTE examination, a suboptimal diffusion of PACS recording, and conservative use of UCA, 3D, and strain. There are significant differences between northern and central-southern regions and echocardiographic laboratories that pertain to the cardiac unit. This inhomogeneous distribution of technology represents one of the main issues that must be solved to standardize the practice of echocardiography
Early probiotic supplementation and the risk of celiac disease in children at genetic risk
- Author
- . ()
- Abbondondolo M. (Michael)
- Aberg S. (Sofie)
- Adamsson A. (Annika)
- Agardh D. (Daniel)
- Ahonen S. (Suvi)
- Akerlund M. (Mari)
- Akolkar B. (Beena)
- Akramoff A. (Ashley)
- Anderson S. W. (Stephen W.)
- Aronsson C. A. (Carin Andren)
- Ask M. (Maria)
- Austin-Gonzalez S. (Sarah)
- Avendano M. (Maryouri)
- Baethke S. (Sandra)
- Ball O. (Olivia)
- Ballard L. (Lori)
- Bautista K. (Kimberly)
- Baxter J. (Judith)
- Becker D. (Dorothy)
- Bennet R. (Rasmus)
- Bingley P. (Polly)
- Bonifacio E. (Ezio)
- Bourcier K. (Kasia)
- Bremer J. (Jenny)
- Briese T. (Thomas)
- Brown R. (Rasheedah)
- Bryant J. (Jennifer)
- Burkhardt B. (Brant)
- Butterworth M. (Martha)
- Chandler K. (Kyla)
- Chavoshi M. (Masumeh)
- Cilio C. (Corrado)
- Clasen J. (Joanna)
- Crouch C. C. (Claire Cowen)
- Cuthbertson D. (David)
- D'Angelo M. (Miryam)
- Daftary A. (Ashi)
- Driscoll K. (Kimberly)
- Dunson K. (Kayleen)
- Eberhard C. (Christopher)
- Ericson-Hallstrom E. (Emelie)
- Erlich H. (Henry)
- Fear A. L. (Anna Lisa)
- Felipe-Morales D. (Daniel)
- Fiske S. (Steven)
- Fors A. (Annika)
- Franciscus M. (Margaret)
- Fransson L. (Lina)
- Frohnert B. I. (Brigitte, I)
- Gallant M. (Marisa)
- Gard T. (Thomas)
- Gardiner M. (Melissa)
- Garmeson J. (Jennifer)
- Gavrisan A. (Anita)
- Gesualdo P. (Patricia)
- Gezginci C. (Cigdem)
- Gowda V. (Veena)
- Grace S. (Sian)
- Hadley D. (David)
- Hagopian W. (William)
- Hagopian W. A. (William A.)
- Haller M. (Michael)
- Hansen M. (Monika)
- Hekkala A. (Anne)
- Hervey R. (Rachel)
- Heublein A. (Anja)
- Heyman K. (Kathleen)
- Hoffman M. (Michelle)
- Hoffmann V. (Verena)
- Holappa H. (Henna)
- Hopkins D. (Diane)
- Hsiao B. (Belinda)
- Hummel S. (Sandra)
- Hyberg S. (Susanne)
- Hyoty H. (Heikki)
- Ikonen A. (Anni)
- Ilonen J. (Jorma)
- Jacobsen L. (Laura)
- Jaminki S. (Sinikka)
- Jisser H. (Hanna)
- Johansen F. (Fredrik)
- Johnson S. B. (Suzanne Bennett)
- Jokipuu S. (Sanna)
- Jonsdottir B. (Berglind)
- Jovic S. (Silvija)
- Kahonen M. (Miia)
- Karban R. (Rachel)
- Karges C. (Christina)
- Karlsson L. (Leena)
- Ke S. (Sandra)
- Keimer A. (Andrea)
- Kelland I. (Ilana)
- Killian M. (Michael)
- Klein M. B. (Mary Beth)
- Knip M. (Mikael)
- Knopff A. (Annette)
- Koch C. (Charlotte)
- Koivikko M.-L. (Minna-Liisa)
- Koletzko S. (Sibylle)
- Koreasalo M. (Mirva)
- Krischer J. P. (Jeffrey P.)
- Kurppa K. (Kalle)
- Kytola J. (Jarita)
- Laras F. P. (Francisco Perez)
- Larsson H. E. (Helena Elding)
- Latva-aho T. (Tiina)
- Lee H.-S. (Hye-Seung)
- Lernmark A. (Ake)
- Li Q. (Qian)
- Lindfors K. (Katri)
- Lindstrom M. (Marielle)
- Liu E. (Edwin)
- Liu S. (Shu)
- Liu X. (Xiang)
- Lonnrot M. (Maria)
- Lundgren M. (Markus)
- Lynch K. (Kristian)
- Lyons R. (Rachel)
- Mack S. J. (Steven J.)
- Maguire C. (Colleen)
- Malloy J. (Jamie)
- Manson-Martinez M. (Maria)
- Mantymaki E. (Elina)
- Markan M. (Maria)
- Marks J. (John)
- Mattila M. (Markus)
- McCarthy C. (Cristina)
- McLeod W. (Wendy)
- Mclndoe R. (Richard)
- Melin J. (Jessica)
- Merrell A. (Aubrie)
- Mestan Z. (Zeliha)
- Meulemans S. (Steven)
- Meyer A. (Arlene)
- Miao D. (Dongmei)
- Mulenga D. (Denise)
- Mulholland N. (Niveen)
- Multasuo K. (Katja)
- Mykkanenv T. (Teija)
- Niininen T. (Titha)
- Niinisto S. (Sari)
- Nilsson C. (Caroline)
- Norris J. (Jill)
- Norris J. M. (Jill M.)
- Nyblom M. (Mia)
- Oikarinen S. (Sami)
- Ollikainen P. (Paula)
- Ottosson K. (Karin)
- Parikh H. (Hemang)
- Pohjola S. (Sirpa)
- Quigley R. (Ryan)
- Radtke J. (Jared)
- Rahmati K. (Kobra)
- Rajala P. (Petra)
- Ramelius A. (Anita)
- Ramminger C. (Claudia)
- Rautanen J. (Jenna)
- Remedios C. (Cassandra)
- Rewers M. (Marian)
- Rewers M. J. (Marian J.)
- Riikonen A. (Anne)
- Romancik M. (Matei)
- Romo M. (Minna)
- Roth R. (Roswith)
- Ruohonen S. (Suvi)
- Salami F. (Falastin)
- Schatz D. (Desmond)
- Schmitt D. (Davey)
- Scholz M. (Marlon)
- Schwabe J. (Julie)
- Shaffer C. (Chris)
- Sharma A. (Ashok)
- She J.-X. (Jin-Xiong)
- Silvis K. (Katherine)
- Simell O. G. (Olli G.)
- Simell S. (Satu)
- Sjoberg A. (Anette)
- Sjoberg B. (Birgitta)
- Sjoberg M. (Maija)
- Skidmore J. (Jennifer)
- Smith L. (Laura)
- Smith M. D. (Maryellen Dalmagro-Elias)
- Smith S. (Susan)
- Steck A. (Andrea)
- Steed L. (Leigh)
- Stenius A. (Aino)
- Stock J. (Joanna)
- Sulman N. (Noah)
- Tamura R. (Roy)
- Tewey D. (Dena)
- Toppari J. (Jorma)
- Torn C. (Carina)
- Tossavainen P. (Paivi)
- Toth M. (Michael)
- Towe P. D. (P. D.)
- Triplett E. (Eric)
- Uusitalo U. (Ulla)
- Vaha-Makila M. (Mari)
- Vainionpaa S. (Sini)
- Varjonen E. (Eeva)
- Vehik K. (Kendra)
- Veijola R. (Riitta)
- Viinikangas I. (Irene)
- Vijayakandipan P. (Ponni)
- Virtanen S. M. (Suvi M.)
- Wallin A. (Anne)
- Warncke K. (Katharina)
- Waugh K. (Kathleen)
- Wendel L. (Lorena)
- Williams A. (Alistair)
- Wimar A. (Asa)
- Winkler C. (Christiane)
- Wood K. (Keith)
- Yang J. (Jimin)
- Yates C. (Chrystal)
- Yu L. (Liping)
- Ziegler A. G. (Anette G.)
- Ziegler A.-G. (Anette-G)
- Zink S. (Sarah)
- Publication venue
- Multidisciplinary Digital Publishing Institute
- Publication date
- 01/01/2019
- Field of study
Abstract
Probiotics are linked to positive regulatory effects on the immune system. The aim of the study was to examine the association between the exposure of probiotics via dietary supplements or via infant formula by the age of 1 year and the development of celiac disease autoimmunity (CDA) and celiac disease among a cohort of 6520 genetically susceptible children. Use of probiotics during the first year of life was reported by 1460 children. Time-to-event analysis was used to examine the associations. Overall exposure of probiotics during the first year of life was not associated with either CDA (n = 1212) (HR 1.15; 95%CI 0.99, 1.35; p = 0.07) or celiac disease (n = 455) (HR 1.11; 95%CI 0.86, 1.43; p = 0.43) when adjusting for known risk factors. Intake of probiotic dietary supplements, however, was associated with a slightly increased risk of CDA (HR 1.18; 95%CI 1.00, 1.40; p = 0.043) compared to children who did not get probiotics. It was concluded that the overall exposure of probiotics during the first year of life was not associated with CDA or celiac disease in children at genetic risk
Metabolite-related dietary patterns and the development of islet autoimmunity
- Author
- Aberg Sofie
- Adamsson Annika
- Agardh Daniel
- Ahonen Suvi
- Akerlund Mari
- Akolkar Beena
- Akramoff Ashley
- Anderson Stephen W.
- Aronsson Carin Andren
- Ask Maria
- Austin-Gonzalez Sarah
- Avendano Maryouri
- Baethke Sandra
- Ball Olivia
- Bautista Kimberly
- Baxter Judith
- Ben Gillard
- Bennet Rasmus
- Beyerlein Andreas
- Bingley Polly
- Bonifacio Ezio
- Bourcier Kasia
- Bremer Jenny
- Briese Thomas
- Brown Rasheedah
- Bryant Jennifer
- Burkhardt Brant
- Butterworth Martha
- Chandler Kyla
- Chavoshi Masumeh
- Cilio Corrado
- Clasen Joanna
- Crouch Claire Cowen
- Crume Tessa
- Cuthbertson David
- D'Angelo Miryam
- DeFelice Brian C.
- Driscoll Kimberly
- Dunson Kayleen
- Eberhard Christopher
- Ericson-Hallstrom Emelie
- Felipe-Morales Daniel
- Fiehn Oliver
- Fiske Steven
- Fors Annika
- Fransson Lina
- Frohnert Brigitte, I
- Gallant Marisa
- Gard Thomas
- Gardiner Melissa
- Garmeson Jennifer
- Gavrisan Anita
- Gesualdo Patricia
- Gezginci Cigdem
- Gowda Veena
- Grace Sian
- Grapov Dmitry
- Hagopian William
- Haller Michael
- Hansen Monika
- Hekkala Anne
- Hervey Rachel
- Heublein Anja
- Heyman Kathleen
- Hoffman Michelle
- Hoffmann Verena
- Holappa Henna
- Hopkins Diane
- Hsiao Belinda
- Hummel Sandra
- Hyberg Susanne
- Hyoty Heikki
- Ikonen Anni
- Ilonen Jorma
- Jacobsen Laura
- Jaminki Sinikka
- Jisser Hanna
- Johansen Fredrik
- Johnson Randi K.
- Johnson Suzanne Bennett
- Jokipuu Sanna
- Jonsdottir Berglind
- Jovic Silvija
- Kahonen Miia
- Karban Rachel
- Karges Christina
- Karlsson Leena
- Ke Sandra
- Kechris Katerina
- Keimer Andrea
- Kelland Ilana
- Killian Michael
- Kind Tobias
- Knip Mikael
- Knopff Annette
- Koch Charlotte
- Koivikko Minna-Liisa
- Koletzko Sibylle
- Koreasalo Mirva
- Krischer Jeffrey
- Kurppa Kalle
- Kytola Jarita
- Laras Francisco Perez
- Larsson Helena Elding
- Latva-aho Tiina
- Lee Hye-Seung
- Lernmark Ake
- Li Qian
- Lindfors Katri
- Lindstrom Marielle
- Liu Edwin
- Liu Shu
- Liu Xiang
- Lonnrot Maria
- Lundgren Markus
- Lynch Kristian
- Lyons Rachel
- Maguire Colleen
- Malloy Jamie
- Mansson-Martinez Maria
- Mantymaki Elina
- Markan Maria
- Marks John
- Mattila Markus
- McCarthy Cristina
- McIndoe Richard
- Melin Jessica
- Merrell Aubrie
- Mestan Zeliha
- Meulemans Steven
- Meyer Arlene
- Miao Dongmei
- Mulenga Denise
- Mulholland Niveen
- Multasuo Katja
- Mykkanen Teija
- Niininen Tiina
- Niinisto Sari
- Nilsson Caroline
- Norris Jill M.
- Nyblom Mia
- Oikarinen Sami
- Ollikainen Paula
- Ottosson Karin
- Palazoglu Mine
- Parikh Hemang
- Pohjola Sirpa
- Quigley Ryan
- Radtke Jared
- Rahmati Kobra
- Rajala Petra
- Ramelius Anita
- Ramminger Claudia
- Rautanen Jenna
- Remedios Cassandra
- Rewers Marian
- Riikonen Anne
- Romancik Matei
- Romo Minna
- Roth Roswith
- Ruohonen Suvi
- Salami Falastin
- Schatz Desmond
- Schmitt Davey
- Scholz Marlon
- Schwabe Julie
- Shaffer Chris
- Sharma Ashok
- She Jin-Xiong
- Silvis Katherine
- Simell Olli G.
- Simell Satu
- Sjoberg Anette
- Sjoberg Birgitta
- Sjoberg Maija
- Skidmore Jennifer
- Smith Laura
- Smith Susan
- Sontag Marci
- Steck Andrea
- Steed Leigh
- Stenius Aino
- Stock Joanna
- Sulman Noah
- Tamura Roy
- Tewey Dena
- Toppari Jorma
- Torn Carina
- Tossavainen Paivi
- Toth Michael
- Towe P. D.
- Triplett Eric
- Uusitalo Ulla
- Vaha-Makila Mari
- Vainionpaa Sini
- Valdiviez Luis
- Vanderlinden Lauren
- Varjonen Eeva
- Vehik Kendra
- Veijola Riitta
- Viinikangas Irene
- Vijayakandipan Ponni
- Virtanen Suvi M.
- Wallin Anne
- Wancewicz Benjamin
- Warncke Katharina
- Waugh Kathleen
- Wendel Lorena
- Wikoff Bill
- Williams Alistair
- Wimar Asa
- Winkler Christiane
- Wohlgemuth Gert
- Wong Joyce
- Wood Keith
- Yang Jimin
- Yu Liping
- Ziegler Anette-G
- Zink Sarah
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study