Hawking Radiation from AdS Black Holes

We investigate Hawking radiation from black holes in (d+1)-dimensional anti-de Sitter space. We focus on s-waves, make use of the geometrical optics approximation, and follow three approaches to analyze the radiation. First, we compute a Bogoliubov transformation between Kruskal and asymptotic coordinates and compare the different vacua. Second, following a method due to Kraus, Parikh, and Wilczek, we view Hawking radiation as a tunneling process across the horizon and compute the tunneling probablility. This approach uses an anti-de Sitter version of a metric originally introduced by Painleve for Schwarzschild black holes. From the tunneling probability one also finds a leading correction to the semi-classical emission rate arising from the backreaction to the background geometry. Finally, we consider a spherically symmetric collapse geometry and the Bogoliubov transformation between the initial vacuum state and the vacuum of an asymptotic observer.Comment: 13 pages, latex2e, v2: some clarifications and references adde

Interacting Kasner-type cosmologies

It is well known that Kasner-type cosmologies provide a useful framework for analyzing the three-dimensional anisotropic expansion because of the simplification of the anisotropic dynamics. In this paper relativistic multi-fluid Kasner-type scenarios are studied. We first consider the general case of a superposition of two ideal cosmic fluids, as well as the particular cases of non-interacting and interacting ones, by introducing a phenomenological coupling function $q(t)$. For two-fluid cosmological scenarios there exist only cosmological scaling solutions, while for three-fluid configurations there exist not only cosmological scaling ones, but also more general solutions. In the case of triply interacting cosmic fluids we can have energy transfer from two fluids to a third one, or energy transfer from one cosmic fluid to the other two. It is shown that by requiring the positivity of energy densities there always is a matter component which violates the dominant energy condition in this kind of anisotropic cosmological scenarios.Comment: Accepted for publication in Astrophysics &Space Science, 8 page

Uncertainties in climate responses to past land cover change: First results from the LUCID intercomparison study

Seven climate models were used to explore the biogeophysical impacts of human-induced land cover change (LCC) at regional and global scales. The imposed LCC led to statistically significant decreases in the northern hemisphere summer latent heat flux in three models, and increases in three models. Five models simulated statistically significant cooling in summer in near-surface temperature over regions of LCC and one simulated warming. There were few significant changes in precipitation. Our results show no common remote impacts of LCC. The lack of consistency among the seven models was due to: 1) the implementation of LCC despite agreed maps of agricultural land, 2) the representation of crop phenology, 3) the parameterisation of albedo, and 4) the representation of evapotranspiration for different land cover types. This study highlights a dilemma: LCC is regionally significant, but it is not feasible to impose a common LCC across multiple models for the next IPCC assessment

Recent advances in neutrinoless double beta decay search

Even after the discovery of neutrino flavour oscillations, based on data from atmospheric, solar, reactor, and accelerator experiments, many characteristics of the neutrino remain unknown. Only the neutrino square-mass differences and the mixing angle values have been estimated, while the value of each mass eigenstate still hasn't. Its nature (massive Majorana or Dirac particle) is still escaping. Neutrinoless double beta decay ($0\nu$-DBD) experimental discovery could be the ultimate answer to some delicate questions of elementary particle and nuclear physics. The Majorana description of neutrinos allows the $0\nu$-DBD process, and consequently either a mass value could be measured or the existence of physics beyond the standard should be confirmed without any doubt. As expected, the $0\nu$-DBD measurement is a very difficult field of application for experimentalists. In this paper, after a short summary of the latest results in neutrino physics, the experimental status, the R&D projects, and perspectives in $0\nu$-DBD sector are reviewed.Comment: 36 pages, 7 figures, To be publish in Czech Journal of Physic

Ellipsoidal area mean gravity anomalies - precise computation of gravity anomaly reference fields for remove-compute-restore geoid determination

Gravity anomaly reference fields, required e.g. in remove-compute-restore (RCR) geoid computation, are obtained from global geopotential models (GGM) through harmonic synthesis. Usually, the gravity anomalies are computed as point values or area mean values in spherical approximation, or point values in ellipsoidal approximation. The present study proposes a method for computation of area mean gravity anomalies in ellipsoidal approximation ('ellipsoidal area means') by applying a simple ellipsoidal correction to area means in spherical approximation. Ellipsoidal area means offer better consistency with GGM quasi/geoid heights. The method is numerically validated with ellipsoidal area mean gravity derived from very fine grids of gravity point values in ellipsoidal approximation. Signal strengths of (i) the ellipsoidal effect (i.e., difference ellipsoidal vs. spherical approximation), (ii) the area mean effect (i.e., difference area mean vs. point gravity) and (iii) the ellipsoidal area mean effect (i.e., differences between ellipsoidal area means and point gravity in spherical approximation) are investigated in test areas in New Zealand and the Himalaya mountains. The impact of both the area mean and the ellipsoidal effect on quasigeoid heights is in the order of several centimetres. The proposed new gravity data type not only allows more accurate RCR-based geoid computation, but may also be of some value for the GGM validation using terrestrial gravity anomalies that are available as area mean values

Adverse events following infusion of T cells for adoptive immunotherapy: A 10-year experience

Background aims. The Food and Drug Administration (FDA) currently recommends at least 4 h of recipient monitoring after T cell infusions to detect early infusion reactions. Recent catastrophic reactions to 'first-in-man' biologic agents have emphasized the importance of this rule for initial studies of new products. The value of such monitoring for better established agents is less obvious. Methods. We reviewed infusion-related adverse events (AE) following administration of ex vivo-expanded T cell products (antigen-specific cytotoxic T lymphocytes, allodepleted T cells, and genetically modified T cells) on investigational new drug (IND) studies in our center. Results. From 1998 to 2008, we infused 381 T cell products to 180 recipients, enrolled on 18 studies, receiving T cells targeting malignancies or post-transplant viral infections. There were no grade 34 infusion reactions during initial monitoring or 24-h follow-up. Twenty-four mild (grade 12) AE occurred in 21 infusions either during or immediately following infusion (up to 6 h), most commonly nausea and vomiting (10/24, 41.6%), probably because of the dimethyl sulfoxide cryoprotectant, and hypotension (20.8%), attributable to diphenhydramine pre-medication. Twenty-two additional non-severe events were reported within 24 h of infusion, most commonly culture-negative fever, chills and nausea. An increased risk of adverse events was associated with age [incidence rate ratio (IRR) 0.98; 95% confidence interval (CI) 0.961.00, P 0.05], while an increased risk of immediate infusion-related events was higher in patients reporting allergies (IRR 2.72, 95% CI 1.007.40, P 0.05); sex, disease type and T cell source (allogeneic or autologous) had no effect on frequency of adverse events. Conclusions. Infusion of these T cell products was safe in the outpatient setting and associated with no severe reactions, so monitoring for 1 h after infusion is probably sufficient. As many of the AE were attributable to diphenhydramine premedication, a lower dose (0.25 mg/kg) should be selected