Capital Flows and Destabilizing Policy in Latin America

Motivated by the excessive macroeconomic volatility experienced in Latin America, we examine the possible contribution of monetary and fiscal policies to this outcome. In contrast with previous literature, we consider the possible simultaneity between policy and GDP growth by using GMM VAR econometric techniques. Additionally, we explore the direct impact international capital inflows have on these policies. Our evidence suggests that for the group of countries we consider, most practice destabilizing fiscal and monetary policy, and capital inflow consistently influences policy in a pro-cyclical direction.Fiscal and Monetary Policies, Capital Flows, Latin America

Interacting Dark Energy: Possible Explanation for 21-cm Absorption at Cosmic Dawn

A recent observation points to an excess in the expected 21-cm brightness temperature from cosmic dawn. In this paper, we present an alternative explanation of this phenomenon, an interaction in the dark sector. Interacting dark energy models have been extensively studied recently and there is a whole variety of such in the literature. Here we particularize to a specific model in order to make explicit the effect of an interaction.Comment: 5 pages, 2 figures. Discussion improved, new references, conclusions unchanged. Accepted in EPJ

Finance and the Business Cycle: a Kalman Filter Approach with Markov Switching

This paper combines two popular econometric tools, the dynamic factor model and the Markov-Switching model, to consider three segments of the financial system- the stock market, debt, and money- and their contribution to US business cycles over the past four decades. The dynamic factor model identifies a composite factor index for each financial segment, and using Markov-switching models by Hamilton (1989) and Filardo (1994), this paper then estimates the effect of each segment index on business cycle behaviour. This reexamination of the finance-business cycle link provides results that prove strongest for the effect of stock market movements on business cycles.

How to break access control in a controlled manner

The Electronic Medical Record (EMR) integrates heterogeneous information within a Healthcare Institution stressing the need for security and access control. The Biostatistics and Medical Informatics Department from Porto Faculty of Medicine has recently implemented a Virtual EMR (VEMR) in order to integrate patient information and clinical reports within a university hospital. With more than 500 medical doctors using the system on a daily basis, an access control policy and model were implemented. However, the healthcare environment has unanticipated situations (i.e. emergency situations) where access to information is essential. Most traditional policies do not allow for overriding. A policy that allows for Break-The-Glass (BTG) was implemented in order to override access control whilst providing for non-repudiation mechanisms for its usage. The policy was easily integrated within the model confirming its modularity and the fact that user intervention in defining security procedures is crucial to its successful implementation and use

Generation of intersubtype human immunodeficiency virus type 1 recombinants in env gene in vitro: Influences in the biological behavior and in the establishment of productive infections

The occurrence of human immunodeficiency virus type 1 (HIV-1) recombinant genomes belonging to different subtypes is a common event in regions where more than two subtypes cocirculate. Although there are accumulating data toward an increase in the number of intersubtype recombinants, little has been addressed about the biological behavior of such mosaic genomes. This work reports the biological characterization of engineered in vitro HIV-1 intersubtype recombinants in the gp120 region. the recombinants possess the entire gp120 of B or F Brazilian Isolates in the Z6 (subtype D) backbone. Hers we show that this type of recombinant structure results in profound impairment to the establishment of productive infections in CD4-positive cells. the characterization of biological properties of those recombinant viruses demonstrated viral production occurring only during a transient peak early on infection and that they are not able to down-regulate the expression of CD4 receptor on the cell surface. We also report the phenotype reversion of one recombinant virus studied here, after 62 days in culture. Two amino acid substitutions in highly constant gp120 regions (C1 and C4) were identified in the revertant virus. the mutation occurring in the C4 region is localized near two amino acid residues critical for gp120/CD4 interaction. Based on these data, we suggest that failure in CD4 down-modulation by recombinant viruses can be due to a structural dysfunction of gp160 protein unable to block CD4 at the endoplasmic reticule. the possibilities that the establishment of latent infections can be directly related to the continuous expression of CD4 on the infected cell surface and that the occurrence of mutations in amino acid nearby residues critical for gp120/CD4 interaction can restore the fully productive infectious process are discussed. (C) 2000 Academic Press.Univ Fed Rio de Janeiro, Inst Biol, Dept Genet, Mol Virol Lab, Rio de Janeiro, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Doencas Infecciosas & Parasitarias, Lab Retrovirol,UNIFESP,EPM, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Doencas Infecciosas & Parasitarias, Lab Retrovirol,UNIFESP,EPM, São Paulo, BrazilWeb of Scienc