39 research outputs found

    Effect of the sensing layer resistivity on sensitivity in DSAWR sensors

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    SAW sensors have become important for gas detection applications in recent years. One of the parameters affecting the sensitivity of SAW sensors is the resistivity of the sensing layer. In this study, it is tried to determine the sensitivities of the sensors for different resistance values for the designed DSAWR. In accordance with this purpose, instead of using actual sensing layers whose resistance can be changed by parameters such as temperature etc., 8 different fixed resistors in the range of 3 to 4M ohms were used to fully demonstrate the effect of the resistance. It has been found that the DSAWR has better sensitivity for active layer resistances between kΩ to a few hundred kΩ

    Effect of taxifolin on acrylamide-induced oxidative and proinflammatory lung injury in rats: Biochemical and histopathological studies

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    Purpose: To examine the probable beneficial effects of taxifolin against acrylamide damage in lung tissue.Methods: 18 male albino Wistar rats were divided into healthy (HG), acrylamide (AG) and taxifolin + acrylamide (TAG) groups. Once a day for 30 days, acrylamide was orally administered to the AG group (50 mg/kg), while ACL (50 mg/kg) and TAX (20 mg/kg) were orally administered to TAG group. Protein concentration, malondialdehyde (MDA), and total glutathione (tGSH) levels as well as oxidant and antioxidant molecules concentrations of the rat lung tissues were measured. In addition, degree of mononuclear (MN) cell infiltration and bronchial-associated lymphoid tissue (BALT) hyperplasia was evaluated by the degree of hyperplasia (absent, mild, moderate, severe). The histopathological andbiochemical data the groups were compared.Results: When compared in terms of MDA levels, it was found that the AG group had high MDA levels, and the TAG group had low MDA levels. (p < 0.001). TAG group was found to have a higher tGSH level than the AG group (p < 0.001). Compared to the AG group, lower TOS and higher TAS levels were obtained in the TAG group (p < 0.001). In addition, when TOS levels of TAG and HG groups were compared, the TOS levels between the two groups were statistically insignificant (p = 0.213). It has been observed that TAX administration prevents the increase in NF-ƘB level. When the NF-ƘB levels of the AG and TAG groups were compared with each other, there was a statistically significant difference (p = 0.001). In the AG group, severe MN cell hyperplasia and BALT hyperplasia were observed histopathologically. It was determined that these findings were alleviated in the TAG group. A histopathologically significant difference was found between AG and TAG groups (p < 0.05).Conclusion: Taxifolin has beneficial effects against lung injury caused by acrylamide, a healthdamaging environmental factor. Regular use of taxifolin can be recommended, especially in people who are known to have intense contact with acrylamide. There is a need for research studies on this subject

    Effects of MWCNTs/graphene nanoflakes/MXene addition to TiO2 thick film on hydrogen gas sensing

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    Various doping materials, such as MWCNTs, graphene nanoflakes and MXene, have been doped into TiO2 and the hydrogen sensing properties investigated. Using a similar volume, MWCNTs (5 wt.%) and graphene nanoflakes (5 wt.%) and MXene (10 wt.%) were added to TiO2 and prepared in a paste form by mixing the sensing material with the organic binder. The sensing film was deposited on an alumina substrate using a screen-printing technique and annealed at 500 °C for 30 min in ambient air. The crystallinity of TiO2 and the doped material in the sensing film after the annealing treatment were verified using FESEM, EDX, XRD and Raman Spectroscopy. By depositing an interdigitated electrode at the bottom of the sensing film, the thick film gas sensors (TiO2/MWCNT, TiO2/Gr, TiO2/MXene) were exposed to 100–1000 ppm of hydrogen at an operating temperature of 100–250 °C. The responses showed that the addition of MWCNTs and MXene to TiO2 reduced the operating temperature of the TiO2 gas sensor from 150 °C to 100 °C, while the addition of graphene nanoflakes did not affect the operating temperature of the TiO2 gas sensor. The TiO2/MWCNT gas sensor showed linear sensitivity as hydrogen concentrations increased for operating temperatures of 100–250 °C. The optimal operating temperature for TiO2/MXene occurred at 100 °C, while the optimal operating temperature for the TiO2/Gr gas sensor occurred at 200 °C. The highest sensitivity for 100–500 ppm hydrogen was generated by the TiO2/MXene gas sensor, and for 600–1000 ppm hydrogen was generated by the TiO2/MWCNT gas sensor at an operating temperature of 250 °C. The TiO2/MWCNT gas sensor produced the highest sensitivity to hydrogen at the operating temperature of 250 °C with sensitivity values of approximately 6.36, 33.61, 67.64, 102.23 and 159.07 for 100, 300, 500, 700 ppm and 1000 ppm of hydrogen, respectively

    Strain variation in early innate cytokine induction by Plasmodium falciparum

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    Previous work has shown that human donors vary in the magnitude and pattern of cytokines induced when peripheral blood mononuclear cells (PBMCs) are co-cultured with Plasmodium falciparum–infected erythrocytes. Whether P. falciparum strains vary in their ability to induce cytokines has not been studied in detail and is an important question, because variation in cytokine induction could affect parasite virulence and patterns of clinical disease. We investigated the early inflammatory cytokine response to four P. falciparum laboratory strains and five field isolates. Initial studies showed that parasite strain, parasitaemia and PBMC donor all had significant effects on the magnitude of pro-inflammatory cytokine responses (IFN-γ, GM-CSF, IL-1β, TNF-α, IL-6, P < 0·005 in all cases). However, we noticed that the most highly inducing parasite strain consistently reached schizont rupture more rapidly than the other strains. When timing of schizont rupture was taken into account, parasite strains no longer differed in their cytokine induction (P = 0·383), although donor effects remained significant (P < 0·001). These data do not support the hypothesis that P. falciparum strains vary in induction of early innate cytokine responses from PBMCs, and instead are consistent with the suggestion that conserved parasite products such as haemozoin or GPI-anchors are the parasite-derived stimuli for cytokine induction

    Influence of breed and parity on teat and milking characterıstıcs ın daıry cattle

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    The aim of this study was to determine some morphological traits of the udder teat and their influence on the milk flow rate in three dairy cattle breeds (Brown Swiss, Holstein and Simmental). The average milking time and milk yield was 8.79±0.16 minutes and 9.40±0.28 kg, respectively. There was a finding that the breed of the dairy cows had no effect on the total milking time, with the Holstein cows having the highest milk yield (P<0.01). The average milk flow rate was 1.09±0.04 kg/minute and the Holstein cows had the highest milk flow rate (P<0.05). The cow parity didn’t affect the milk flow rate and the milk yield. The average teat length, average teat diameter and average teat volume varied among the cattle breeds and were highest in the Brown Swiss, and lowest in the Simmental cows. In conclusion, the milk flow rate varies among cattle breeds, and it was observed that dairy cows with high milk yields have higher milk flow rates

    Utility Of M30, An Apoptotic Serum Marker, In Liver Diseases

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    The aim of this paper is to evaluate the role of apoptosis in some common liver diseases, and the utility of M30, an apoptotic serum marker, in the diagnosis of the severity of underlying hepatic injury. As is widely known, apoptosis is programmed cell death, and its deregulation results in an uncontrolled inflammatory process leading to upregulation of liver fibrogenesis. Both extrinsic and intrinsic pathways are crucial in apoptosis, and caspase cleavage of cytokeratin proteins occurs in both. Therefore, the measurement of caspase-cleaved cytokeratin fragments could be a novel method to assess the intensity of apoptotic cell numbers in epithelial tissue damage. M30 levels were found to increase not only in acute liver disorders, but also in some chronic liver injuries. We tried to summarize the recent studies focused on the role of apoptotic processes in liver diseases, mainly those that investigated the use of M30 in determining the severity of, or in predicting, ongoing liver injury.WoSScopu

    Anovestibular fistula with imperforate anus in two adults

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    Applications of sulfonate-carboxylate copolymers in cement

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    Copolymers of methoxy polyethyleneglycol (meth) acrylate (mPEG(M)A) and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) were synthesised, characterised with Fourier transform infrared spectroscopy and gel permeation chromatography, and the effects of molecular architecture on the properties of cement-based systems were investigated. Superplasticiser (SP) adsorption was determined with a total organic carbon analyser, while spread and mechanical properties were assessed according to European standards. The rheological behaviour of cement pastes at different copolymer dosages was also studied. Sufficient fluidity and fluidity retention over time are requirements for the mixing, transportation, pumping and moulding of concrete at construction sites. The synthesised SPs with long side chains provided mortars with high fluidity, high dispersing power per adsorption ratio and low mechanical strength compared with the SPs with short side chains. They were also effective at decreasing the shear yield stresses and plastic viscosities (at high dosages) of the cement pastes. Additionally, mortars dosed with mPEG(M) A-co-AMPS had higher fluidity and fluidity-retaining properties compared with mortars prepared with lignosulfonate-type SP

    Asymptomatic intracranial hemorrhage in a newborn with congenital factor VII deficiency and successful treatment with recombinant activated factor VII.

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    Intracranial hemorrhage is considered the most common cause of death in newborns with congenital factor VII (FVII) deficiency. Recombinant activated FVII (rFVIIa) provides specific replacement therapy, however there is limited experience with its neonatal use. We describe our experience about the treatment of intracranial hemorrhage in a newborn with congenital FVII deficiency and emphasize the importance of imaging in asymptomatic patients. She presented with ecchymoses on her skin, no other pathological clinical signs, prolonged PT, normal PTT and FVII activity of 2%. Intracranial hemorrhage was diagnosed while screening for internal bleedings. Treatment with rFVIIa resulted in stabilization and regression of the hematoma
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