Wynik w skali CHA2DS2-VASc jako czynnik predykcyjny nefropatii pokontrastowej u chorych z zawałem serca z uniesieniem odcinka ST poddanych pierwotnej interwencji wieńcowej

Background and aim: We aimed to investigate the predictive value of the CHA2DS2-VASc score in the development of contrast-induced nephropathy (CIN). Methods: A total of 2972 patients who had been diagnosed with ST elevation myocardial infarction (STEMI) and who had undergone primary coronary angioplasty were included in the study. The patients were divided into three groups according to the CHA2DS2-VASc score, i.e.: low risk (1 point), intermediate risk (2 points), and high risk (≥ 3 points). The groups were followed with regard to CIN development. Results: The median CHA2DS2-VASc score was significantly higher in the CIN(+) group compared to the CIN(–) group (3 vs. 2, p 1 (OR 4.25, 95% CI 3.10–5.82, p < 0.001) were found to be independent predictors for CIN development. Conclusions: The CHA2DS2-VASc score is an independent and strong predictor of CIN development in patients with acute STEMI.Wstęp: Badanie przeprowadzono w celu oceny wartości predykcyjnej skali CHA2DS2-VASc w odniesieniu do ryzyka rozwoju nefropatii pokontrastowej (CIN). Metody: Do badania włączono 2972 chorych, u których zdiagnozowano zawał serca z uniesieniem odcinka ST (STEMI) i wykonano pierwotną angioplastykę wieńcową. Uczestników badania podzielono na trzy grupy w zależności od wyniku w skali CHA2DS2-VASc: grupa niskiego ryzyka (1 punkt), grupa pośredniego ryzyka (2 punkty) i grupa wysokiego ryzyka (≥ 3 punkty). Wszystkie grupy obserwowano pod kątem rozwoju CIN. Wyniki: Mediana wyników w skali CHA2DS2-VASc była istotnie wyższa w grupie CIN(+) niż w grupie CIN(–) (3 vs. 2; p 1 (OR 4,25; p < 0,001) były niezależnymi czynnikami predykcyjnymi rozwoju CIN. Wnioski: Wynik w skali CHA2DS2-VASc jest silnym i niezależnym czynnikiem predykcyjnym rozwoju CIN u chorych z ostrym STEMI

Postoperative morbidities following dental care under day-stay general anesthesia in intellectually disabled children

WOS: 000233700800006PubMed ID: 16297693Purpose: The objective of this study was to compare the postoperative morbidities for 24 hours following dental care under day-stay general anesthesia using sevoflurane or halothane in intellectually disabled children. Materials and Methods: Eighty-six premedicated patients with intellectual disabilities under-went general anesthesia for their dental treatment. They were randomly given anesthesia maintained with sevoflurane (2% to 3%) or halothane (1% to 1.5%) after receiving inhalation induction either with sevoflurane (8%) or halothane (5%) and nitrous oxide in oxygen (50:50). The patients' age, gender, weight, ASA Class, type of dental treatment, and duration of anesthesia and operation were recorded as well as the time required for recovery (Aldrete Scale) and the length of time taken before they were discharged (postanesthetic discharge scoring system) from the hospital. Pain and agitation were recorded using a visual analog scale (0 to 10). Other postoperative morbidities, which include crying, nausea and vomiting, bleeding, and drowsiness, were also noted for 24 hours after the operation. Results: The most common morbidities during the postoperative 24 hours were agitation and pain, and their occurrence was significantly more common in the sevoflurane group than in the halothane group (P < .05). The recovery time was shorter in the sevoflurane group, but it was not statistically significant. There was no difference between the groups in the discharge time. Conclusions: Apart from more postoperative agitation and pain after awakening from sevoflurane, the quality of recovery was similar for both sevoflurane and halothane. (c) 2005 American Association of Oral and Maxillofacial Surgeons

A Single Clone Acinetobacter baumannii Outbreak in a State Hospital in Turkey

ERTURK, AYSE/0000-0001-6413-9165WOS: 000320094900014PubMed: 23698489Acinetobacter baumannii is an important pathogen in hospitalized patients, particularly those in the intensive care unit (ICU). A total of 21 A. baumannii (6 from 5 patients and 15 from environmental samples) were isolated in the ICU and the isolation room of a state hospital in June 2011. The possible source of the outbreak was investigated. A. baumannii isolates were identified using conventional biochemical tests, BBL Crystal Identification Systems, OXA-51 specific PCR, and 16S rDNA sequencing. All the isolates were multidrug-resistant, showing resistance to cephalosporins, carbapenems, fluoroquinolones, and the aminoglycoside group of antibiotics. Pulsed-field gel electrophoresis suggested that all A. baumannii isolates were derived from a common source

The Role of Trace Elements in the Malignant-Benign Differentation of Pleural Effusions

WOS: 000376566800018Aim: It has been speculated that trace elements may play a role in some type of cancers. The aim of the present study was to examine the diagnostic utility of trace elements in pleural fluid with pleural effusions. Material and Method: This study consisted of 38 patients diagnosed with malignant and benign pleural effusions. Chrome, nickel, selenium, copper, lead and zinc concentrations in samples were determined by inductively coupled plasma optical emission spectrometry. Results: No significant difference was found between malignant and benign effusions with respect to Cr, Cu, Ni, Pb, Se and Zn concentrations in samples. Discussion: Trace elements have function as the component of many enzymes and the catalyst of some chemical reactions. There have been studies demonstrating the association of the deficiency or surplus of trace elements (TEs) with various type of cancers. In our study, the role of TEs measured in the pleural effusions in the differential diagnosis in the effusion etiology could not be demonstrated

Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction

Objectives Red cell distribution width (RDW), a measure of red blood cell size heterogeneity, was evaluated in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI)