650 research outputs found
SHIELD CURRENT INDUCED NOISE IN AUDIO CABLES
Take an experimental research the "shield-current-induced noise" measurement results for various types of audio cables and developed the circuit model to simulate a behavior of the various length cables in the 10 kHz – 4 MHz range
HyperLoom possibilities for executing scientific workflows on the cloud
We have developed HyperLoom - a platform for defining and executing scientific workflows in large-scale HPC systems. The computational tasks in such workflows often have non-trivial dependency patterns, unknown execution time and unknown sizes of generated outputs. HyperLoom enables to efficiently execute the workflows respecting task requirements and cluster resources agnostically to the shape or size of the workflow. Although HPC infrastructures provide an unbeatable performance, they may be unavailable or too expensive especially for small to medium workloads. Moreover, for some workloads, due to HPCs not very flexible resource allocation policy, the system energy efficiency may not be optimal at some stages of the execution. In contrast, current public cloud providers such as Amazon, Google or Exoscale allow users a comfortable and elastic way of deploying, scaling and disposing a virtualized cluster of almost any size. In this paper, we describe HyperLoom virtualization and evaluate its performance in a virtualized environment using workflows of various shapes and sizes. Finally, we discuss the Hyperloom potential for its expansion to cloud environments.61140639
HyperLoom: A platform for defining and executing scientific pipelines in distributed environments
Real-world scientific applications often encompass end-to-end data processing pipelines composed of a large number of interconnected computational tasks of various granularity. We introduce HyperLoom, an open source platform for defining and executing such pipelines in distributed environments and providing a Python interface for defining tasks. HyperLoom is a self-contained system that does not use an external scheduler for the actual execution of the task. We have successfully employed HyperLoom for executing chemogenomics pipelines used in pharmaceutic industry for novel drug discovery.6
Synthesis of nitroxyl radical by direct nucleophilic functionalization of a C-H bond in the azadiene systems
Cyclic dinitrones underwent nucleophilic substitution of the hydrogen atom in the reaction with a paramagnetic carbanion, the lithium derivative of 4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide, to give polyfunctional nitronyl nitroxyls. © 2012 Springer Science+Business Media New York
Cyclotrimerization of 3-R-1,2,4-triazin-5(4H)-ones with cyclic ketones
New heterocyclic tetracyclic systems were synthesized. Interaction between 3-R-1,2,4-triazin-5(4H)-ones and cyclic ketones under acidic conditions leads to the formation of zwitterion derivatives of 5,6,7,8,9,10,11,12-octahydro-[1,2,4] triazino[1,6- f ]phenanthridine and 1,2,3,6,7,8-hexahydro-bicyclopenta[b,d] pyrido[1,2- f ][1,2,4]triazine. © 2010 Verlag der Zeitschrift für Naturforschung, Tübingen
Chemodivergence in Metal-Catalyzed Cross-Dehydrogenative Coupling Reactions of 2H-imidazole 1-oxides with 1H-pyrrole
This work was supported by the Russian Science Foundation (Project # 18-73-00088)
Synthesis of 4-hydroxy and 6-hydroxyindoles: a renaissance of the Bischler reaction
In the present work we studied a modified Bischler-Möhlau reaction – synthesis of indoles from benzoin and aniline. Our proposed modification of this method differs from that described earlier in that the reaction is carried out at a lower temperature, which makes it possible to improve yields and reduce formation of tarry side products. In addition, unlike the previous contradictory works, which described the preparation of a single 4-hydroxy or 6-hydroxy isomer in condensation of m-aminophenol and benzoin, we obtained both 4-hydroxy and 6-hydroxy isomers
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