What data characteristics are needed for data reuse in the domain of social sciences in Korea?

With the benefits of data sharing and reuse, data reuse have been promoted in various domains. While there are practices and discussions regarding data sharing and reuse, we still have little knowledge on what characteristics of data impact decisions on data reuse. In this sense, we aim to explore data characteristics in the context of data reuse within the domain of social sciences in Korea. For the purpose of this study, we conducted in-depth interviews with twelve re-searchers in the field of social science in terms of six dimensions: data producer, country/language, data type/collection method, procedure, accessibility, size/currency. For the producer dimension, social scientists preferred data that have been produced by an institution rather than an individual researcher. In language used in the data sets, English were more favored because researchers preferred English than any other languages. In terms of data type, quantitative and survey data types are preferred. For the procedure of data, researchers preferred original raw data with plenty of metadata and demographic information for analysis. For accessibility, there was less preference for restricted data. Lastly, for size/currency, researchers showed a preference for big size data and current data. These preliminary findings can provide better understanding about data reuse and guide improved data reuse services

A Framework of Automatic Subject Term Assignment: An Indexing Conception-Based Approach

The purpose of dissertation is to examine whether the understandings of subject indexing processes conducted by human indexers have a positive impact on the effectiveness of automatic subject term assignment through text categorization (TC). More specifically, human indexers' subject indexing approaches or conceptions in conjunction with semantic sources were explored in the context of a typical scientific journal article data set. Based on the premise that subject indexing approaches or conceptions with semantic sources are important for automatic subject term assignment through TC, this study proposed an indexing conception-based framework. For the purpose of this study, three hypotheses were tested: 1) the effectiveness of semantic sources, 2) the effectiveness of an indexing conception-based framework, and 3) the effectiveness of each of three indexing conception-based approaches (the content-oriented, the document-oriented, and the domain-oriented approaches). The experiments were conducted using a support vector machine implementation in WEKA (Witten, & Frank, 2000). The experiment results pointed out that cited works, source title, and title were as effective as the full text, while keyword was found more effective than the full text. In addition, the findings showed that an indexing conception-based framework was more effective than the full text. Especially, the content-oriented and the document-oriented indexing approaches were found more effective than the full text. Among three indexing conception-based approaches, the content-oriented approach and the document-oriented approach were more effective than the domain-oriented approach. In other words, in the context of a typical scientific journal article data set, the objective contents and authors' intentions were more focused that the possible users' needs. The research findings of this study support that incorporation of human indexers' indexing approaches or conception in conjunction with semantic sources has a positive impact on the effectiveness of automatic subject term assignment

Graduate Recital: Eunkyung Son, Cello; Wejing Lui, Piano; Jiyoun Chung, Piano; Andrew Francois, Violin; April 25, 2010

Kemp Recital HallApril 25, 2010Sunday Afternoon1:30 p.m

Measuring the maturity of open access: a preliminary study

Open access is an important part of scholarly communication, and it has been a global phenomenon. The growth of open access brings several signif-icant benefits to the general public as well as researchers, ultimately leads to the advancement of science. For the continuous growth and development of open access, it is necessary to measure the degree of maturity of open ac-cess. However, there is not much discussion about the assessment frame-work for open access. This study aims to propose an assessment framework of open access maturity. For the purpose of this study, we conducted an analysis with a total of 24 literatures relevant to the digital maturity, the ma-turity of open data/open science, and major open access initiatives. For digi-tal maturity, 18 articles were analyzed: 10 articles for generic purpose model, and 8 articles for industry-specific model. In addition, three articles on the maturity of open data/open science were analyzed and three major open ac-cess initiatives. In preliminary analysis results, three dimensions with 13 be-longing items were proposed for measuring the maturity of open access. Three dimensions are OA Policy, OA capability, and Openness quality. For OA policy, there are three items such as OA policy document, OA govern-ance, and OA strategy. For OA Capability, finance for OA, people for OA, culture for OA, and collaboration for OA are proposed. For Openness Quali-ty dimension, six items are suggested: submission and review, author rights, user rights, findability, accessibility, and monitoring

The associations of continuity of care with inpatient, outpatient, and total medical care costs among older adults with urinary incontinence

Introduction Urinary incontinence is a significant health problem with considerable social and economic consequences among older adults. The objective of this study was to investigate the financial impact of continuity of care (CoC) among older urinary incontinence patients in South Korea. Methods We used the NHIS-Senior cohort patient data between January 1, 2010, and December 31, 2010. Patients who were diagnosed with urinary incontinence in 2010 were included. Operational definition of CoC included referrals, number of providers, and number of visits. A generalized linear model (GLM) with γ-distributed errors and the log link function was used to examine the relationship between health cost and explanatory variables. Additionally, we conducted a two-part model analysis for inpatient cost. Marginal effect was calculated. Results Higher CoC was associated with a decrease in total medical cost (-0.63, P < .0001) and in outpatient costs (-0.28, P < .001). Higher Charlson Comorbidity Index (CCI) score was a significant predictor for increasing total medical cost (0.59, P < .0001) and outpatient cost (0.22, P < .0001). Higher CoC predict a reduced medical cost of $360.93 for inpatient cost (P = 0.044) and$23.91 for outpatient cost (P = 0.008) per patient. Conclusion Higher CoC was associated with decrease in total medical costs among older UI patients. Policy initiatives to promote CoC of older UI patients in the community setting could lead to greater financial sustainability of public health insurance in South Korea.This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors

International Implementation of Digital Library Software/Platforms

Presented at the ASIS&T Annual Meeting, Vancouver BC, Canada, November 11, 2009.This panel will present an overview of adoption and implementation of digital library software/platforms and standards with an international perspective. Decision factors in adoption of particular software/platform and standards are reviewed. Impact of organizational, social, legal, and cultural factors are highlighted

Opposing Regulation of PROX1 by Interleukin-3 Receptor and NOTCH Directs Differential Host Cell Fate Reprogramming by Kaposi Sarcoma Herpes Virus

Lymphatic endothelial cells (LECs) are differentiated from blood vascular endothelial cells (BECs) during embryogenesis and this physiological cell fate specification is controlled by PROX1, the master regulator for lymphatic development. When Kaposi sarcoma herpes virus (KSHV) infects host cells, it activates the otherwise silenced embryonic endothelial differentiation program and reprograms their cell fates. Interestingly, previous studies demonstrated that KSHV drives BECs to acquire a partial lymphatic phenotype by upregulating PROX1 (forward reprogramming), but stimulates LECs to regain some BEC-signature genes by downregulating PROX1 (reverse reprogramming). Despite the significance of this KSHV-induced bidirectional cell fate reprogramming in KS pathogenesis, its underlying molecular mechanism remains undefined. Here, we report that IL3 receptor alpha (IL3Rα) and NOTCH play integral roles in the host cell type-specific regulation of PROX1 by KSHV. In BECs, KSHV upregulates IL3Rα and phosphorylates STAT5, which binds and activates the PROX1 promoter. In LECs, however, PROX1 was rather downregulated by KSHV-induced NOTCH signal via HEY1, which binds and represses the PROX1 promoter. Moreover, PROX1 was found to be required to maintain HEY1 expression in LECs, establishing a reciprocal regulation between PROX1 and HEY1. Upon co-activation of IL3Rα and NOTCH, PROX1 was upregulated in BECs, but downregulated in LECs. Together, our study provides the molecular mechanism underlying the cell type-specific endothelial fate reprogramming by KSHV

Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia

SPONASTRIME dysplasia is a rare, recessive skeletal dysplasia characterized by short stature, facial dysmorphism, and aberrant radiographic findings of the spine and long bone metaphysis. No causative genetic alterations for SPONASTRIME dysplasia have yet been determined. Using whole-exome sequencing (WES), we identified bi-allelic TONSL mutations in 10 of 13 individuals with SPONASTRIME dysplasia. TONSL is a multi-domain scaffold protein that interacts with DNA replication and repair factors and which plays critical roles in resistance to replication stress and the maintenance of genome integrity. We show here that cellular defects in dermal fibroblasts from affected individuals are complemented by the expression of wild-type TONSL. In addition, in vitro cell-based as-says and in silico analyses of TONSL structure support the pathogenicity of those TONSL variants. Intriguingly, a knock-in (KI) Tonsl mouse model leads to embryonic lethality, implying the physiological importance of TONSL. Overall, these findings indicate that genetic variants resulting in reduced function of TONSL cause SPONASTRIME dysplasia and highlight the importance of TONSL in embryonic development and postnatal growth.Peer reviewe

Korean Adolescents’ Understandings of Social Equalities and Inequalities

Equality is a central issue in morality, and a desire for equality has resulted in major historical changes in human societies. The issues regarding social inequalities among different social groups are complex because they often involve multiple players bringing in varying claims, demands, and perspectives. Thus, individuals need to coordinate multiple considerations in coming to judgments about fairness. However, research on equality has not been sufficiently extensive to fully understand the development and application of concepts of equality to social inequalities that exist among different social groups and processes of coordination involved in making judgments about equality. This study examined Korean adolescents’ judgments and reasoning about social inequalities. Eighty-four adolescents from three age groups (12-13, 14-15, and 16-17 years) were administered individual interviews. Participants were presented with hypothetical situations depicting unequal allocations of resources among different groups based on social class, race, and gender. Participants were first asked to evaluate the inequalities. Then, they were presented with a set of questions that measured whether their evaluations would change in the face of personal and conventional contingencies (i.e. personal assertions, dictates from authorities or a rule, cultural generalizability). Participants’ reasoning was assessed through elicitation of justifications for each question. As a follow-up of a study that was conducted with American adolescents, Korean adolescents’ judgments and reasoning about social inequalities were compared with those of American adolescents. The findings showed that Korean adolescents have developed understandings about equality, and they apply concepts of equality in making judgments about fairness. Although the majority of adolescents evaluated the inequalities in all situations as unacceptable, fewer made negative evaluations in the social class situations than in the race and gender situations. The negative evaluations about the inequalities in the race and gender situations were not contingent on personal assertions, the directives from authorities, the dictates of a rule, or culturally accepted practices. Those negative evaluations were justified with reasons of welfare and equality. In the two social-class situations, more positive evaluations were made and based on moral justifications of merit, as well as on conventional justifications. Justifications based on personal choices were common in the situation that pertained to differences in the amount of lunch money. Korean adolescents’ judgments and reasoning about the social inequalities were largely in line with those of American adolescents. A few differences were observed. One was that American adolescents primarily used moral reasons of welfare and equality whereas Korean adolescents also took into consideration moral concerns of merit and property rights. Another was that racial inequality invoked concerns about welfare of immigrants as well as maintaining equality for Korean adolescents, whereas the latter was a single main concern for American adolescents