Anaesthetic effects of xylazine combinations in high and low concentrations of tiletamine-zolazepam, with and without ketamine, in cats

Intramuscular (1M) administration of four anaesthetic combinations were evaluated on nine cats ina repeated manner. The anaesthetic regimens were: (i) 2 mg/kg tiletamine, 2 mg/kg zolazepam, 3.2 mg/kg ketamine and 0.8 mg/kg xylazine (T₄KX); (ii) 1 mg/kg tiletamine, 1 mg/kg zolazepam, 3.2 mg/kg ketamine and 0.8 mg/kg xylazine (T₂KX); (iii) 2 mg/kg tiletamine, 2 mg/kg zolazepam and 0.8 mg/kg xylazine (T₄X); and (iv) 1 mg/kg tiletamine, 1 mg/kg zolazepam and 0.8 mg/kg xylazine (T2X). All four combinations induced smooth recumbency within 4 minutes following IM administration and enabled intubation. All four anaesthetic combinations caused an immediate increase in heart rate and a dramatic decrease in respiratory rate. Pale to slight cyanotic mucous membrane was observed in most cats, 5 minutes following administration of any of the anaesthetic combinations. The T₄KX combination provided the longest duration of anaesthesia, followed by T₂KX, T₄X and T₂X, Time from IM injection to righting reflex, sternal recumbency, and standing or walking, was longest after administration of T₄KX, followed by T₄X, T₂X and T₂KX. Quality of recovery from anaesthesia was better following T₂X and T₂KX administration compared to T₄X and T₄KX. This study demonstrates the benefits of adding ketamine in the anaesthetic combination to reduce the tiletaminezolazepam component. The data in this study can be used to compare and choose an initial IM TKX induction dose for short and non-invasive procedures in cats

How to Reduce Unexpected eMBMS Session Disconnection: Design and Performance Analysis

In 3GPP eMBMS, sometimes sessions will be disconnected unexpectedly due to the miss of session keys. Although rekeying can prevent old users from getting multicast data, it also causes authorized users to miss subsequent data if they miss the key update messages. Thus, re-authentication is needed to obtain lost keys from KMM. We point out this problem in our previous work 1. In this paper, we further propose a new KeySet algorithm, which can pre-issue a number of keys to users when they join eMBMS. The advantage is that a user can still decode multicast data even if it misses some key updates tentatively. However, the cost is that allowing some old users to freely enjoying multicast for some time. In this paper, we quantify the tradeoff and derive the optimal case

Multi-Slot Allocation Protocols for Massive IoT Devices with Small-Size Uploading Data

The emergence of Internet of Things applications introduces new challenges such as massive connectivity and small data transmission. In traditional data transmission protocols, an ID (i.e., IP address or MAC address) is usually included in a packet so that its receiver is able to know who sent the packet. However, this introduces the big head-small body problem for light payload. To address this problem, the Hint protocols have been proposed. The main idea is to 'encode' information in a tiny broadcast Hint message that allows devices to 'decode' their transmission slots. Thus, it can significantly reduce transmission and contention overheads. In this letter, we extend eHint to support multi-slot data transmissions. Several efficient protocols are proposed. Our simulation results validate that the protocols can significantly increase the number of successfully transmitted devices, channel utilization, and payload of transmitted devices compared with eHint

Design and Analysis of the Key Management Mechanism in Evolved Multimedia Broadcast/Multicast Service

3GPP introduced the key management mechanism (KMM) in evolved multimedia broadcast/multicast service (eMBMS) to provide forward security and backward security for multicast contents. In this paper, we point out that KMM may lead to frequent rekeying and re-authentication issues due to eMBMS's characteristics: 1) massive group members; 2) dynamic group topology; and 3) unexpected wireless disconnections. Such issues expose extra load for both user equipment (UE) terminals and mobile operators. It seems prolonging the rekeying interval is an intuitive solution to minimizing the impact of the issues. However, a long rekeying interval is not considered the best operational solution due to revenue loss of content providers. This paper quantifies the tradeoff between the load of the UEs and the operators as well as the revenue loss of the content providers. Moreover, we emphasize how essential this rekeying interval has impacts on the problems. Using our proposed tradeoff model, the operators can specify a suitable rekeying interval to best balance the interest between the above three parties. The tradeoff model is validated by extensive simulations and is demonstrated to be an effective approach for the tradeoff analysis and optimization on eMBMS

eHint: An Efficient Protocol for Uploading Small-Size IoT Data

IoT (Internet of Things) has attracted a lot of attention recently. IoT devices need to report their data or status to base stations at various frequencies. The IoT communications observed by a base station normally exhibit the following characteristics: (1) massively connected, (2) lightly loaded per packet, and (3) periodical or at least mostly predictable. The current design principals of communication networks, when applied to IoT scenarios, however, do not fit well to these requirements. When a large number of devices contend to send small packets, the signaling overhead is not cost-effective. To address this problem, our previous work [1] proposes the Hint protocol, which is slot-based and schedule- oriented for uploading IoT devices' data. In this work, we extend [1] to support data transmissions for multiple resource blocks. We assume that the uplink payloads from IoT devices are small, each taking very few slots (or resource blocks), but devices are massive. The main idea is to "encode" information in a tiny broadcast that allows each device to "decode" its transmission slots, thus significantly reducing transmission overheads and contention overheads. Our simulation results verify that the protocol can significantly increase channel utilization compared with traditional schemes

Application of theory of planned behavior to predict recreational sports activities participation of students in Malaysia

This study aims to understand the factors that influence the participation of high school students in recreational sports activities using the “Theory of Planned Behavior” (TPB) (Ajzen, 1991). Questionnaires that were adapted from Cunningham and Kwon (2003) were used to measure the reasons for participation of recreational sports among high school students in Malaysia. The respondents consisted of 101 high school students from the age of 13 to16. Analyses of data include descriptive statistics, Pearson Product-Moment‘s correlation and standard multiple regression. The findings showed that there is a significant relationship between attitude factor and subjective norms with behavioral intention to participate in recreational sports activities. This study proposed intervention measures to increase the participation of high school students in recreational sports in Malaysia

Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes

Iron fatty acid complexes (IFACs) are prepared via the dissolution of porous hematite powder in hot unsaturated fatty acid. The IFACs are then decomposed in five different organic solvents under reflux conditions in the presence of the respective fatty acid. The XRD analysis results indicate that the resulting NPs comprise a mixture of wustite, magnetite, and maghemite phases. The solvents with a higher boiling point prompt the formation of larger NPs containing wustite as the major component, while those with a lower boiling point produce smaller NPs with maghemite as the major component. In addition, it is shown that unstable NPs with a mixed wustite–magnetite composition can be oxidized to pure maghemite by extending the reaction time or using an oxidizing agent

Effect of small-sided games rule changes on time spent in different intensity zones, frequency of technical actions and distance covered during soccer training

Link to publisher's homepage at http://www.mohejournal.com/index.php/mohePurpose: The efficacy of SSGs has been difficult to assess as researchers have used a wide-ranging number of players, pitch dimensions and game rules, making comparisons complicated. Therefore, this study compared four SSG rules [one (SSG1T), two (SSG2T), three (SSG3T), and unlimited touches (SSGFT)] on time spent in different heart-rate (HR) intensity zones, frequency of technical actions and distance covered involving the starting 11 players and the reserve goalkeeper of a national soccer league team. Methods: The participants (age: 24.3±4.0 yr; height: 171.2±5.9 cm: weight: 61.9±7.4 kg) were measured for previously mentioned dependent variables during each SSG format. Results: Analysis found no significant difference among the four SSGs formats [F(3, 27) = 2.897, p = .053] for time spent in the low-intensity zone, but significant differences were observed for time spent in moderate [F(3, 27) = 13.642, p = .001] and high [F(3, 27) = 13.431, p = .001] intensity zones. Significantly more time was spent in the high intensity zone [F(3, 27) = 13.431, p = .001] when players performed SSG2T and SSGFT when compared SSG1T (p = .002 and p = .009) respectively. SSG1T induced most unsuccessful passing [F(3,27) = 500.498, p = .001] but no differences was observed among SSG2T, SSG3T and SSGFT. SSG2T, SSG3T and SSG3T obtained significantly more shots on goal shots on goal [F(3,27) = 25.398, p = .001], with SSGFT achieving higher numbers than the other three formats. There were no significant differences in goals scored (p = .537) and distance covered (p = 0.574) for all SSG formats. Conclusion: The main findings of this study revealed that all four SSG formats stimulated moderate to high heart rate intensities that could induce positive aerobic and anaerobic adaptations depending on frequency of technical actions and players’ skill level. Therefore, coaches could select specific SSG formats to help players achieved intended intensity and technical objectives programmed for different phases of periodized training

DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: A comprehensive profiling approach

10.1186/1471-230X-14-55BMC Gastroenterology141-BGMA

Teacher led school-based surveillance can allow accurate tracking of emerging infectious diseases - evidence from serial cross-sectional surveys of febrile respiratory illness during the H1N1 2009 influenza pandemic in Singapore

10.1186/1471-2334-12-336BMC Infectious Diseases12-BIDM