7,516 research outputs found
Traffic by multiple species of molecular motors
We study the traffic of two types of molecular motors using the two-species
symmetric simple exclusion process (ASEP) with periodic boundary conditions and
with attachment and detachment of particles. We determine characteristic
properties such as motor densities and currents by simulations and analytical
calculations. For motors with different unbinding probabilities, mean field
theory gives the correct bound density and total current of the motors, as
shown by numerical simulations. For motors differing in their stepping
probabilities, the particle-hole symmetry of the current-density relationship
is broken and mean field theory fails drastically. The total motor current
exhibits exponential finite-size scaling, which we use to extrapolate the total
current to the thermodynamic limit. Finally, we also study the motion of a
single motor in the background of many non-moving motors.Comment: 23 pages, 6 figures, late
Off-policy Q-learning: set-point design for optimizing dual-rate rougher flotation operational processes
Rougher flotation, composed of unit processes operating at a fast time scale and economic performance measurements known as operational indices measured at a slower time scale, is very basic and the first concentration stage for flotation plants. Optimizing operational process for rougher flotation circuits is extremely important due to high economic profit arising from the optimality of operational indices. This paper presents a novel off-policy Q-learning method to learn theoptimal solution to rougher flotation operational processes without the knowledge of dynamics of unit processes and operational indices. To this end, first, the optimal operational control (OOC) for dual-rate rougher flotationprocesses is formulated. Second, H∞ tracking control problem is developed to optimally prescribe the set-points for the rougher flotation processes. Then, a zero-sum game off-policy Q-learning algorithm is proposed to find theoptimal set-points by using measured data. Finally, simulation experiments are employed to show the effectiveness of the proposed method
The activation energy for GaAs/AlGaAs interdiffusion
Copyright 1997 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Journal of Applied Physics 82, 4842 (1997) and may be found at
Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.
Chondrogenic mesenchymal stem cells (MSCs) have not yet been used to address the clinical demands of large osteochondral joint surface defects. In this study, self-assembling tissue intermediates (TIs) derived from human periosteum-derived stem/progenitor cells (hPDCs) were generated and validated for stable cartilage formation in vivo using two different animal models.status: publishe
Models for Enhanced Absorption in Inhomogeneous Superconductors
We discuss the low-frequency absorption arising from quenched inhomogeneity
in the superfluid density rho_s of a model superconductor. Such inhomogeneities
may arise in a high-T_c superconductor from a wide variety of sources,
including quenched random disorder and static charge density waves such as
stripes. Using standard classical methods for treating randomly inhomogeneous
media, we show that both mechanisms produce additional absorption at finite
frequencies. For a two-fluid model with weak mean-square fluctuations <(d
rho_s)^2 > in rho_s and a frequency-independent quasiparticle conductivity, the
extra absorption has oscillator strength proportional to the quantity <(d
rho_s)^2>/rho_s, as observed in some experiments. Similar behavior is found in
a two-fluid model with anticorrelated fluctuations in the superfluid and normal
fluid densities. The extra absorption typically occurs as a Lorentzian centered
at zero frequency. We present simple model calculations for this extra
absorption under conditions of both weak and strong fluctuations. The relation
between our results and other model calculations is briefly discussed
Band structure of ZnO from resonant x-ray emission spectroscopy
Soft x-ray emission and absorption spectroscopy of the O K-edge are employed
to investigate the electronic structure of wurtzite ZnO(0001). A quasiparticle
band structure calculated within the GW approximation agrees well with the
data, most notably with the energetic location of the Zn3d - O2p hybridized
state and the anisotropy of the absorption spectra. Dispersion in the band
structure is mapped using the coherent k-selective part of the resonant x-ray
emission spectra. We show that a more extensive mapping of the bands is
possible in the case of crystalline anisotropy such as that found in ZnO.Comment: 5 pages, 5 figure
Tuning LDA+U for electron localization and structure at oxygen vacancies in ceria
We examine the real space structure and the electronic structure (particularly Ce4f electron localization) of oxygen vacancies in CeO2 (ceria) as a function of U in density functional theory studies with the rotationally invariant forms of the LDA+U and GGA+U functionals. The four nearest neighbor Ce ions always relax outwards, with those not carrying localized Ce4f charge moving furthest. Several quantification schemes show that the charge starts to become localized at U≈3eV and that the degree of localization reaches a maximum at ∼6eV for LDA+U or at ∼5.5eV for GGA+U. For higher U it decreases rapidly as charge is transferred onto second neighbor O ions and beyond. The localization is never into atomic corelike states; at maximum localization about 80–90% of the Ce4f charge is located on the two nearest neighboring Ce ions. However, if we look at the total atomic charge we find that the two ions only make a net gain of (0.2–0.4)e each, so localization is actually very incomplete, with localization of Ce4f electrons coming at the expense of moving other electrons off the Ce ions. We have also revisited some properties of defect-free ceria and find that with LDA+U the crystal structure is actually best described with U=3–4eV, while the experimental band structure is obtained with U=7–8eV. (For GGA+U the lattice parameters worsen for U>0eV, but the band structure is similar to LDA+U.) The best overall choice is U≈6eV with LDA+U and ≈5.5eV for GGA+U, since the localization is most important, but a consistent choice for both CeO2 and Ce2O3, with and without vacancies, is hard to find
Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction
published_or_final_versio
Multiplicity Distributions in Canonical and Microcanonical Statistical Ensembles
The aim of this paper is to introduce a new technique for calculation of
observables, in particular multiplicity distributions, in various statistical
ensembles at finite volume. The method is based on Fourier analysis of the
grand canonical partition function. Taylor expansion of the generating function
is used to separate contributions to the partition function in their power in
volume. We employ Laplace's asymptotic expansion to show that any equilibrium
distribution of multiplicity, charge, energy, etc. tends to a multivariate
normal distribution in the thermodynamic limit. Gram-Charlier expansion allows
additionally for calculation of finite volume corrections. Analytical formulas
are presented for inclusion of resonance decay and finite acceptance effects
directly into the system partition function. This paper consolidates and
extends previously published results of current investigation into properties
of statistical ensembles.Comment: 53 pages, 7 figure
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