Neumonía necrotizante inducida por Escherichia coli extraintestinal patogénica (ExPEC) en felinos

La Escherichia coli extraintestinal patogénica (ExPEC) es una de las bacterias más comunes encontradas enel tracto gastrointestinal de humanos y animales. ExPEC se caracteriza por producir enfermedad en otrosórganos fuera del tracto gastrointestinal. Este grupo ha sido implicado en infecciones del tracto urinario,meningitis, septicemia y neumonía en humanos y animales. En este estudio se muestran las implicancias dedistintas ExPEC en el desarrollo de neumonía en un refugio para gatos, en donde mueren de manera abrupta13 de 35 gatos; y en un tigre recientemente destetado y transportado en una caja para un programa detelevisión. En todos los casos, se observa neumonía necrotizante y fibrinosa, con la presencia de coloniasbacterianas intralesionales. El cultivo y la tipificación de los genotipos de virulencia demuestran la presenciade factores que son comunes para estas bacterias, como son hemolisina D, papGI y papGIII y cnf-1. Comopatogenia, se propone que una vez inhalada la bacteria, la presencia de hemolisina y cnf-1 reduce larespuesta inflamatoria aguda en pulmón, bloqueando la llegada e induciendo muerte de neutrófilos,disparando además edema, necrosis e inflamación. Interesantemente, hemolisinas y cnf-1 son encontrados enExPEC aisladas de humanos que padecen infecciones del tracto urinario y otros sitios extraintestinales. Enconclusión, Las infecciones por ExPEC en felinos es una entidad emergente, que se caracteriza por eldesarrollo de neumonía necrotizante que es frecuentemente fatal, y que este agente tiene un potencialzoonótico debido a su similitud entre las bacterias aisladas en humanos y animales, sumado a la cercaníaentre ambas especies.  

Histopathological lesions compatible with nymphs of Linguatula serrata in bovine liver

Linguatula serrata is the causative parasite of Linguatulosis, a disease that not only produces economic losses in cattle but also represents a public health risk due to its zoonotic nature. This study aimed to microscopically characterise the compatible lesions produced by this parasite in bovine liver collected at a slaughterhouse in the city of Curicó, Chile. Histologic compatible lesions with Linguatulosis were observed in 18 out of 269 livers. Furthermore, nymphs were visualised in 3 cases, allowing an etiologic diagnosis. Microscopic lesions containing nymphs demonstrated two patterns of inflammatory reactions, one pattern with a predominance of eosinophils, accompanied by lymphocytes and some macrophages, and another pattern with a predominance of lymphocytes and plasma cells with some macrophages. A microscopic characterisation was performed in compatible lesions without nymphs (n=15), defining 4 types of granulomas attributable to visceral Linguatulosis, according to the presence and features of cells at the centre of the lesion, the presence of presumably degenerated nymphal structures, location of inflammatory infiltrate, as well as location and amount of surrounding fibrous tissue. These lesions can concede a presumptive microscopic diagnosis. Also, different microscopic features of granulomas compatible with Linguatulosis analysed in this study suggest a temporal evolution of the lesions. The description of lesions generates a better understanding of the host-parasite interaction of this agent which has importance in both animal productivity and public health

Prevalence of bovine hepatic linguatuliasis in a slaughterhouse in Talca, Chile

El objetivo del estudio fue determinar la prevalencia de linguatulosis en hígados de bovinos beneficiados en una planta faenadora de Talca, Chile. Se examinaron 376 hígados y se registró la presencia de lesiones compatibles a linguatulosis, así como la presencia de la ninfa de Linguatula serrata. El 13.8% de los hígados presentaron lesiones compatibles con linguatulosis y en el 48% de estos se llegó al diagnóstico etiológico. No se encontraron diferencias significativas por grupo etario (p=0.187). En el 28% de hígados con diagnóstico etiológico, la linguatulosis fue la única enfermedad parasitaria, en el 60% estuvo asociada con distomatosis y en un solo caso con un quiste hidatídico. La prevalencia de linguatulosis en hígados de bovinos fue de 6.7%, con base en la presencia de ninfas de L. serrata.The aim of this study was to determine the prevalence of hepatic linguatuliasis of cattle slaughtered in an abattoir in Talca, Chile. Livers (n=376) were examined and compatible lesions and the presence of the nymph of Linguatula serrata were recorded. The results showed that 13.8% of livers showed lesions compatible with linguatulosis and the etiologic diagnosis was obtained in 48% of them. No significant differences by age group (p=0.187) were found. In 28% of livers with etiologic diagnosis, linguatuliasis was the only parasitic disease, 60% was associated with liver fluke and in one case with one hydatid cyst. The prevalence of hepatic linguatuliasis was 6.7% based on the presence of L. serrata nymphs

Neumonía necrotizante inducida por Escherichia coli extraintestinal patogénica (ExPEC) en felinos

La Escherichia coli extraintestinal patogénica (ExPEC) es una de las bacterias más comunes encontradas enel tracto gastrointestinal de humanos y animales. ExPEC se caracteriza por producir enfermedad en otrosórganos fuera del tracto gastrointestinal. Este grupo ha sido implicado en infecciones del tracto urinario,meningitis, septicemia y neumonía en humanos y animales. En este estudio se muestran las implicancias dedistintas ExPEC en el desarrollo de neumonía en un refugio para gatos, en donde mueren de manera abrupta13 de 35 gatos; y en un tigre recientemente destetado y transportado en una caja para un programa detelevisión. En todos los casos, se observa neumonía necrotizante y fibrinosa, con la presencia de coloniasbacterianas intralesionales. El cultivo y la tipificación de los genotipos de virulencia demuestran la presenciade factores que son comunes para estas bacterias, como son hemolisina D, papGI y papGIII y cnf-1. Comopatogenia, se propone que una vez inhalada la bacteria, la presencia de hemolisina y cnf-1 reduce larespuesta inflamatoria aguda en pulmón, bloqueando la llegada e induciendo muerte de neutrófilos,disparando además edema, necrosis e inflamación. Interesantemente, hemolisinas y cnf-1 son encontrados enExPEC aisladas de humanos que padecen infecciones del tracto urinario y otros sitios extraintestinales. Enconclusión, Las infecciones por ExPEC en felinos es una entidad emergente, que se caracteriza por eldesarrollo de neumonía necrotizante que es frecuentemente fatal, y que este agente tiene un potencialzoonótico debido a su similitud entre las bacterias aisladas en humanos y animales, sumado a la cercaníaentre ambas especies.  

Coccidioidomycosis in 26 horses in California, USA: case series and review of the literature.

Coccidioidomycosis is a fungal disease caused by Coccidioides immitis or Coccidioides posadasii. We searched the records of the California Animal Health and Food Safety Laboratory from 1990 through 2020 for cases of coccidioidomycosis in horses. The selection criteria for these cases were: 1) live-born horses submitted for autopsy, and 2) a diagnosis of coccidioidomycosis was established, regardless of cause of death. During that time, 19,054 horses were received, and 26 cases (0.14%) of coccidioidomycosis were diagnosed in horses, of which 19 (73%) cases had pneumonia and/or pleuritis with or without lesions in other organs, and 7 (27%) cases had lesions only in organs other than the lungs (nasal mucosa, spleen, thoracic lymph nodes, heart, pericardial sac, liver, kidney, mediastinum, and/or mesentery). Pneumonia was diagnosed as the cause of death in 1,838 (9.64%) of the horses received; Coccidioides spp. was the cause of pneumonia in 19 (1.0%) of these animals. Horses have been reported to have low susceptibility to coccidioidomycosis, and the severity and chronicity of the disease can be variable. Lesions in our cases consisted of multifocal-to-coalescing pyogranulomas with intralesional fungal spherules. Coccidioidomycosis must be considered a differential diagnosis in cases of persistent cough, chronic weight loss, fever, and cases with a travel history to, or living in, a region considered endemic for coccidioidomycosis. Coccidioides spp. infection should also be considered when pyogranulomatous inflammation is found within lung, spleen, nasal mucosa, and lymph nodes of horses

Arab Springs making space: territoriality and moral geographies for asylum seekers in Italy

© 2016 Brazilain Coll Veterinary Parasitology. All rights reserved. Toxoplasmosis is an infectious, zoonotic and parasitic disease, caused by Toxoplasma gondii. In this manucript, two cases of infection with T. gondii in captive animals from a zoological park in the central region of Chile are described. One case was a red kangaroo (Macropus rufus), which is highly susceptible to the infection, and the other was a Patagonian mara (Dolichotis patagonum), a rodent in which there is no previous report of the infection. Both animals had myocarditis, with the presence of intralesional tachizoites and cysts suggestive of infection with T. gondii. This infection was confirmed by immunohistochemistry in both animals. The origin of the infection is unknown, but it is likely that free ranging domestic felines were associated with the dissemination of the parasites. This highlights the importance of controlling the domestic animal populations in zoological parks. To the best of our knowledge, th

Infection with Toxoplasma gondii in a red kangaroo (Macropus rufus) and a Patagonian mara (Dolichotis patagonum) in captivity

Abstract Toxoplasmosis is an infectious, zoonotic and parasitic disease, caused by Toxoplasma gondii. In this manucript, two cases of infection with T. gondii in captive animals from a zoological park in the central region of Chile are described. One case was a red kangaroo (Macropus rufus), which is highly susceptible to the infection, and the other was a Patagonian mara (Dolichotis patagonum), a rodent in which there is no previous report of the infection. Both animals had myocarditis, with the presence of intralesional tachizoites and cysts suggestive of infection with T. gondii. This infection was confirmed by immunohistochemistry in both animals. The origin of the infection is unknown, but it is likely that free ranging domestic felines were associated with the dissemination of the parasites. This highlights the importance of controlling the domestic animal populations in zoological parks. To the best of our knowledge, this is the first time that T. gondii infection is described in a Patagonian mara, adding a new host for this infectious agent