3,392 research outputs found
Rooted in History: Historic Preservation as a Foundation for Community Engagement Along the Lower Schuylkill
Once the centerpiece of a rolling pastoral landscape, punctuated by some of the most important ornamental and botanical gardens of the colonial and early national eras, the Lower Schuylkill metamorphosed over the next century into one of the most polluted and environmentally degraded waterways in the country. In this thesis I will discuss the historical, environmental, and political themes that have shaped the evolution of the Lower Schuylkill region. Reviewing analyses and critiques of neoliberal urbanism, particularly in the context of waterfront revitalization projects, I identify ways in which preservation and related fields might support or resist a development-driven agenda. I then consider PIDCâs Lower Schuylkill Master Plan, which outlines a long-term vision for the extension of the Schuylkill river trail, and identify ways in which it fits within the neoliberal framework. Through further analysis of Executive Summaries, Master Plans, Reports, public meeting notes, and other public documents, I discuss how aspects of the Lower Schuylkill Master Plan utilize historic resources to promote a development agenda. I then propose ways in which the preservation of a broad range of resources related to various eras of the regionâs history might facilitate deeper community engagement with the space
Quantitative immunohistochemical analysis of matrilysin 1 (MMP-7) in various renal cell carcinoma subtypes.
The role of matrilysin 1 or matrix metalloproteinase-7 (MMP-7) in cancer is extremely complex and poorly understood. In this study we investigated differential expression of MMP-7 in the epithelium and stroma of 95 paraffin-embedded renal tumor samples by immunohistochemistry and compared tumoral with normal peritumoral renal tissue. We also determined a possible correlation of the immunohistochemical findings with histological subtype, tumor grade and stage of RCC. In all areas examined MMP-7 protein expression was significantly higher in epithelium than in stroma (P<.01). MMP-7 was more less expressed in peritumoral normal areas than in benign epithelial neoplasias (renal papillary and oncocytomas) and RCC carcinomas, reaching the highest immunopositive reaction in chromophobe RCC subtypes, followed by conventional clear-cell and chromophilic-papillary RCC histological subtypes and the lowest levels in more aggressive RCC histotypes (spindle-cell and collecting-duct RCCs). MMP-7 reached their highest levels in high-grade and high-stage RCCs. Our observation suggests an important role of MMP-7 in the development and progression of renal cancer. The differential expression of MMP-7 in the various histological RCC subtypes may reflect the malignant phenotype and more aggressive behavior of RCCs
Physical Electronics and Surface Physics
Contains research objectives and summary of research on one research project.Joint Services Electronics Program (Contract DAAB07-74-C-0630
Correlating densities of centrality and activities in cities : the cases of Bologna (IT) and Barcelona (ES)
This paper examines the relationship between street centrality and densities of commercial and service activities in cities. The aim is to verify whether a correlation exists and whether some 'secondary' activities, i.e. those scarcely specialized oriented to the general public and ordinary daily life, are more linked to street centrality than others. The metropolitan area of Barcelona (Spain) is investigated, and results are compared with those found in a previous work on the city of Bologna (Italy). Street centrality is calibrated in a multiple centrality assessment (MCA) model composed of multiple measures such as closeness, betweenness and straightness. Kernel density estimation (KDE) is used to transform data sets of centrality and activities to one scale unit for correlation analysis between them. Results indicate that retail and service activities in both Bologna and Barcelona tend to concentrate in areas with better centralities, and that secondary activities exhibit a higher correlation
Physical Electronics and Surface Physics
Contains reports on one research project.Joint Services Electronics Program (Contract DAAB07-71-C-0300
Post-fire management of cork oak forests
28 pĂĄginas, 11 figuras.This chapter concerns the ecology and post-fire management of cork oak forests. It starts with a short overview of ecological and socio-economic context, continuing with an introduction on the cork oak post-fire regeneration strategies and the main factors affecting tree responses. Several post-fire management issues and alternatives, such as tree logging, assisting natural regeneration, reforestation, cork harvesting and pruning, or protecting against herbivory, are also presented and discussed.To all people who contributed in some way to the contents of this chapter, with special thanks to Francisco Rego, Paulo Fernandes and Thomas Curt. To Fundação para a CiĂȘncia e a Tecnologia (PhD grant SFRH/BD/65991/2009), FFP (project Recuperação de Ăreas Ardidas), EU (COST FP0701 and TRANZFOR), and the Spanish government (project VARQUS, CGL2004-4325/BOS).Peer reviewe
Action Concepts in the Brain: An Activation Likelihood Estimation Meta-Analysis
Many recent neuroimaging studies have investigated the representation of semantic memory for actions in the brain. We used activation likelihood estimation (ALE) meta-analyses to answer two outstanding questions about the neural basis of action concepts. First, on an âembodiedâ view of semantic memory, evidence to date is unclear regarding whether visual motion or motor systems are more consistently engaged by action concepts. Second, few studies have directly investigated the possibility that action concepts accessed verbally or nonverbally recruit different areas of the brain. Because our meta-analyses did not include studies requiring the perception of dynamic depictions of actions or action execution, we were able to determine whether conceptual processing alone recruits visual motion and motor systems. Significant concordance in brain regions within or adjacent to visual motion areas emerged in all meta-analyses. By contrast, we did not observe significant concordance in motor or premotor cortices in any analysis. Neural differences between action images and action verbs followed a gradient of abstraction among representations derived from visual motion information in the left lateral temporal and occipital cortex. The consistent involvement of visual motion but not motor brain regions in representing action concepts may reflect differences in the variability of experience across individuals with perceiving versus performing actions
Does gender diversity on banksâ boards matter? Evidence from public bailouts
This is the final version. Available on open access from Elsevier via the DOI in this recordWe are the first to examine the impact of gender diversity on banksâ boards on the probability and size of public bailouts. Our findings, based on a sample of listed European banks over the period 2005-2017, suggest that banks with more gender-diverse boards are less likely to receive a public bailout and receive a lower
amount of bailout funds as a percentage of total assets than banks with less gender-diverse boards. Specifically, an increase by one standard deviation in gender diversity decreases the probability of a bailout by at least 2.44%, a significant reduction considering that the unconditional probability is 18.7%. Gender diversity is also
positively related to bank performance, as proxied by ROA and Tobinâs Q and with dividend payout ratios, consistent with the hypothesis that female directors are better monitors than male directors. These results are robust to a variety of econometric approaches and provide support for recent reforms in several EU countries
regarding gender quotas
- âŠ