The common feeder cockroach Blaptica dubia shows increased transmission distance based on mode of acquisition of environmental bacteria

Although some researchers claim that cockroaches are masters of disease transmission, these claims have little to no scientific support. Most studies concerning cockroaches as a vector of disease only focus on the bacteria found on the body surface, not on whether cockroaches have actually transferred pathogenic bacteria via surface contact. We set out to determine if cockroaches would act as a mechanical vector for the transfer of the opportunistic pathogen, E. coli. Roaches were contaminated with Green fluorescent protein expressing E. coli (GFP-E.coli) broth by either walking the roach through a broth culture or by complete immersion in the culture.. We then ran the roaches down a sterile agar track and measured the length of the glowing trail. Roaches were able to transmit E.coli, but only for a continuous distance of less than 50 cm, with the occasional sporadic colony growing after that. Roaches that were immersed in bacterial broth tracked the bacterium further than those that only walked through the solution. This suggests that while cockroaches are capable of acting as a mechanical vector, they are not capable of transporting transient flora over long distances. Future studies should explore this mechanism

Climate Change Challenges for Extension Educators: Technical Capacity and Cultural Attitudes

We surveyed Extension educators in the southern Great Plains about their attitudes and beliefs regarding climate change, their interactions with constituents surrounding climate change, and challenges they face in engaging constituents on the topic of climate change. Production-oriented and sociocultural challenges in meeting constituents\u27 information needs exist. Educators reported (a) lacking capacity for addressing climate change issues and (b) needing information, especially regarding drought and extreme or unseasonable weather events and related management practices. Educators also identified a need for more educational resources, including print materials and online decision aids. Implications are relevant to educators working beyond the study area and in any agricultural production system

Beyond Low-Earth Orbit: Characterizing Immune and microRNA Differentials following Simulated Deep Spaceflight Conditions in Mice

Spaceflight missions can cause immune system dysfunction in astronauts with little understanding of immune outcomes in deep space. This study assessed immune responses in mice following ground-based, simulated deep spaceflight conditions, compared with data from astronauts on International Space Station missions. For ground studies, we simulated microgravity using the hindlimb unloaded mouse model alone or in combination with acute simulated galactic cosmic rays or solar particle events irradiation. Immune profiling results revealed unique immune diversity following each experimental condition, suggesting each stressor results in distinct circulating immune responses, with clear consequences for deep spaceflight. Circulating plasma microRNA sequence analysis revealed involvement in immune system dysregulation. Furthermore, a large astronaut cohort showed elevated inflammation during low-Earth orbit missions, thereby supporting our simulated ground experiments in mice. Herein, circulating immune biomarkers are defined by distinct deep space irradiation types coupled to simulated microgravity and could be targets for future space health initiatives

Climate outlooks serving agriculture

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Smartphone accessibility: Understanding the lived experience of users with cervical spinal cord injuries

Purpose: To explore accessibility challenges encountered by smartphone users with cervical spinal cord injuries (C1-C8).To investigate the suitability of current technology and make recommendations to help future technology meet user needs. Methods: The study uses a mixed-method approach combining an inductive thematic analysis of nine semi-structured interviews with a quantitative analysis of thirty-nine questionnaires. Results: The analysis generated four themes: ’the drive for independence and self-efficacy’; ’trying to make it work’; ’getting the right technology for me’; ’using the phone as and when I want to’. These themes highlighted how unresolved access issues and situational barriers limited independence and created unwanted privacy compromises for effective communication. There was a lack of information or support on available smartphone accessibility features and assistive technology (AT). Smartphone AT was regarded as overpriced, poorly designed and lacking the voices of people with disabilities. Conclusions: The smartphone’s potential to improve quality of life, participation, and well-being is limited by accessibility challenges hindering independent and private smartphone use. Future design work should focus on improving accessibility, investigating reasons for AT’s poor quality and high cost, and removing barriers to end-user inclusion. To enhance user awareness of available technology, stakeholders should build and maintain an open platform to act as an information source for peer and professional support on assistive technology

LET-Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of miRNAs that Drive Inhibition

Space radiation inhibits angiogenesis by two mechanisms depending on the linear energy transfer (LET). Using human 3D micro-vessel models, blockage of the early motile stage of angiogenesis was determined to occur after exposure to low LET ions (/AMU), whereas inhibition of the later stages occurs after exposure to high LET ions (\u3e8 KeV/AMU). Strikingly, the combined effect is synergistic, detectible as low as 0.06 Gy making mixed ion space radiation more potent. Candidates for bystander transmission are microRNAs (miRNAs), and analysis on miRNA-seq data from irradiated mice shows that angiogenesis would in theory be downregulated. Further analysis of three previously identified miRNAs showed downregulation of their targets associated with angiogenesis and confirmed their involvement in angiogenesis pathways and increased health risks associated with cardiovascular disease. Finally, synthetic molecules (antagomirs) designed to inhibit the predicted miRNAs were successfully used to reverse the inhibition of angiogenesis

Agricultural producer perceptions of climate change and climate education needs for the Central Great Plains

Citation: Hibbs, Amber Campbell, Daniel Kahl, Lisa PytlikZillig, Ben Champion, Tarik Abdel-Monem, Timothy Steffensmeier, Charles W. Rice, and Kenneth Hubbard. “Agricultural Producer Perceptions of Climate Change and Climate Education Needs for the Central Great Plains.” Journal of Extension 52, no. 3 (June 2014). https://www.joe.org/joe/2014june/a2.php.The Central Great Plains Climate Education Partnership conducted focus groups throughout Kansas to gain a better understanding of farmer perceptions and attitudes towards climate change education. Results indicate concern about climatic changes, even if producers are unsure that "human caused climate change" is occurring. Participants indicated they would like access to information through Web-based programs that allow them to manipulate variables relevant to their area and situation. Participants prefer locally relevant information and identified Extension agents as trusted educators. The study provided an expanded understanding of agricultural producer perceptions that will be valuable to individuals or organizations providing climate education

Spin state and moment of inertia of Venus

Fundamental properties of the planet Venus, such as its internal mass distribution and variations in length of day, have remained unknown. We used Earth-based observations of radar speckles tied to the rotation of Venus obtained in 2006-2020 to measure its spin axis orientation, spin precession rate, moment of inertia, and length-of-day variations. Venus is tilted by 2.6392 $\pm$ 0.0008 degrees ($1\sigma$) with respect to its orbital plane. The spin axis precesses at a rate of 44.58 $\pm$ 3.3 arcseconds per year ($1\sigma$), which gives a normalized moment of inertia of 0.337 $\pm$ 0.024 and yields a rough estimate of the size of the core. The average sidereal day on Venus in the 2006-2020 interval is 243.0226 $\pm$ 0.0013 Earth days ($1\sigma$). The spin period of the solid planet exhibits variations of 61 ppm ($\sim$20 minutes) with a possible diurnal or semidiurnal forcing. The length-of-day variations imply that changes in atmospheric angular momentum of at least $\sim$4% are transferred to the solid planet.Comment: 20 pages, 7 figures, supplementary information. Submitted to Nature Astronomy on October 14, 202

Working together to increase Australian children’s liking of vegetables: A position statement by the vegetable intake strategic alliance (VISA)

Children need to be repeatedly and consistently exposed to a variety of vegetables from an early age to achieve an increase in vegetable intake. A focus on enjoyment and learning to like eating vegetables at an early age is critical to forming favourable lifelong eating habits. Coordinated work is needed to ensure vegetables are available and promoted in a range of settings, using evidence-based initiatives, to create an environment that will support children’s acceptance of vegetables. This will help to facilitate increased intake, and ultimately realise the associated health benefits. The challenges and evidence base for a new approach are described