793 research outputs found
Etude du mode dâaction des insecticides de nouvelle gĂ©nĂ©ration actifs sur les canaux sodium dâinsecte
Pressure profiles of distant galaxy clusters in the Planck catalog
Successive releases of Planck data have demonstrated the strength of the
Sunyaev--Zeldovich (SZ) effect in detecting hot baryons out to the galaxy
cluster peripheries. To infer the hot gas pressure structure from nearby galaxy
clusters to more distant objects, we developed a parametric method that models
the spectral energy distribution and spatial anisotropies of both the Galactic
thermal dust and the Cosmic Microwave Background, that are mixed-up with the
cluster SZ and dust signals. Taking advantage of the best angular resolution of
the High Frequency Instrument channels (5 arcmin) and using X-ray priors in the
innermost cluster regions that are not resolved with Planck, this modelling
allowed us to analyze a sample of 61 nearby members of the Planck catalog of SZ
sources (, ) using the full mission data, as
well as to examine a distant sample of 23 clusters (, ) that have been recently followed-up with XMM-Newton and Chandra
observations. We find that (i) the average shape of the mass-scaled pressure
profiles agrees with results obtained by the Planck collaboration in the nearby
cluster sample, and that (ii) no sign of evolution is discernible between
averaged pressure profiles of the low- and high-redshift cluster samples. In
line with theoretical predictions for these halo masses and redshift ranges,
the dispersion of individual profiles relative to a self-similar shape stays
well below 10 % inside but increases in the cluster outskirts.Comment: 12 pages, 10 figure
Etude des sous-unitĂ©s auxiliaires du canal sodium dĂ©pendant du potentiel chez lâinsecte : approches molĂ©culaires, Ă©lectrophysiologiques et pharmacologiques (ThĂšse de Doctorat d'UniversitĂ©)
Voltage-gated sodium (Nav) channel is a crucial molecular component of the cellular excitability. It represents a target of choice for neurotoxic insecticides used in pest control. Pyrazoline-type insecticide interacts with the main Nav channel subunit with a preference for its inactivated state. A recent study showed that auxiliary subunits of Drosophila melanogaster modified this conformation. However, little information is available concerning the role and the regulation of these auxiliary subunits. The objectives of this thesis were to characterize the auxiliary subunits of the American cockroach Periplaneta americana by molecular, electrophysiological and pharmacological approaches, in order to specify their functions. The first part of this work concerns the neuronal TEH1 subunit. Two variants, PaTEH1A and PaTEH1B resulting from an intron retention modifying only the C-terminal extremity, were cloned. Using the heterologous expression system Xenopus oocytes and the two microelectrodes voltage clamp technique, we highlighted that the C-terminal extremity was involved in the modulation of Nav channels electrophysiological and pharmacological properties. The second part concerns the discovery of other auxiliary subunits. We identified several variants resulting from alternative splicing events (2 variants for PaTipE and 4 for PaTEH2). Altogether, our results indicate that auxiliary subunits are diverse and play an important role in the modulation of Na+ current and should be considered to improve pharmacological studies
Shapley Supercluster Survey: Ram-Pressure Stripping vs. Tidal Interactions in the Shapley Supercluster
We present two new examples of galaxies undergoing transformation in the
Shapley supercluster core. These low-mass (stellar mass from 0.4E10 to 1E10
Msun) galaxies are members of the two clusters SC-1329-313 (z=0.045) and
SC-1327-312 (z=0.049). Integral-field spectroscopy complemented by imaging in
ugriK bands and in Halpha narrow-band are used to disentangle the effects of
tidal interaction (TI) and ram-pressure stripping (RPS). In both galaxies,
SOS-61086 and SOS-90630, we observe one-sided extraplanar ionized gas extending
respectively 30kpc and 41kpc in projection from their disks. The galaxies'
gaseous disks are truncated and the kinematics of the stellar and gas
components are decoupled, supporting the RPS scenario. The emission of the
ionized gas extends in the direction of a possible companion for both galaxies
suggesting a TI. The overall gas velocity field of SOS-61086 is reproduced by
ad hoc N-body/hydrodynamical simulations of RPS acting almost face-on and
starting about 250Myr ago, consistent with the age of the young stellar
populations. A link between the observed gas stripping and the cluster-cluster
interaction experienced by SC-1329-313 and A3562 is suggested. Simulations of
ram pressure acting almost edge-on are able to fully reproduce the gas velocity
field of SOS-90630, but cannot at the same time reproduce the extended tail of
outflowing gas. This suggests that an additional disturbance from a TI is
required. This study adds a piece of evidence that RPS may take place in
different environments with different impacts and witnesses the possible effect
of cluster-cluster merger on RPS.Comment: 27 pages, 28 figures, MNRAS accepte
A2163: Merger events in the hottest Abell galaxy cluster II. Subcluster accretion with galaxy-gas separation
Located at z = 0.203, A2163 is a rich galaxy cluster with an intra-cluster
medium (ICM) that exhibits extraordinary properties, including an exceptionally
high X-ray luminosity, average temperature, and a powerful and extended radio
halo. The irregular and complex morphology of its gas and galaxy structure
suggests that this cluster has recently undergone major merger events that
involve two or more cluster components. In this paper, we study the gas
structure and dynamics by means of spectral-imaging analysis of X-ray data
obtained from XMM-Newton and Chandra observations. From the evidence of a cold
front, we infer the westward motion of a cool core across the E-W elongated
atmosphere of the main cluster A2163-A. Located close to a galaxy over-density,
this gas 'bullet' appears to have been spatially separated from its galaxy (and
presumably dark matter component) as a result of high-velocity accretion.
From gas brightness and temperature profile analysis performed in two
opposite regions of the main cluster, we show that the ICM has been
adiabatically compressed behind the crossing 'bullet' possibly because of shock
heating, leading to a strong departure of the ICM from hydrostatic equilibrium
in this region. Assuming that the mass estimated from the Yx proxy best
indicates the overall mass of the system and that the western cluster sector is
in approximate hydrostatic equilibrium before subcluster accretion, we infer a
merger scenario between two subunits of mass ratio 1:4, leading to a present
total system mass of M500 . The exceptional
properties of A2163 present various similarities with those of 1E0657-56, the
so-called 'bullet-cluster'. These similarities are likely to be related to a
comparable merger scenario.Comment: A&A, in pres
Particle dynamics in a non-flaring solar active region model
The aim of this work is to investigate and characterise particle behaviour in a (observationally-driven) 3D MHD model of the solar atmosphere above a slowly evolving, non-flaring active region. We use a relativistic guiding-centre particle code to investigate particle acceleration in a single snapshot of the 3D MHD simulation. Despite the lack of flare-like behaviour in the active region, direct acceleration of electrons and protons to non-thermal energies (âČ 42 MeV) was found, yielding spectra with high-energy tails which conform to a power law. Examples of particle dynamics, including particle trapping caused by local electric rather than magnetic field effects, are observed and discussed, together with implications for future experiments which simulate non-flaring active region heating and reconnection.Publisher PDFPeer reviewe
Stress fluctuation, crack renucleation and toughening in layered materials
It has been established that contrast in the elastic properties can lead to enhancement of fracture toughness in heterogeneous materials. Focussing on layered materials as a model system, we show that this enhancement is a result of two distinct phenomena â first, fluctuations in stress leading to regions where the stress intensity at the crack is considerably smaller than that of the macroscopically applied value; and second, the lack of stress intensity when a crack is at a compliant to stiff interface thereby requiring renucleation. Using theoretical, computational and experimental methods, we study two geometries â a layered material and a layered material with a narrow channel â to separate the two phenomena. The stress fluctuation is present in both, but renucleation is present only in the layered medium. We provide quantitative estimates for the enhanced toughness
RĂ©gulation du courant sodique chez lâinsecte par Ă©pissage alternatif des gĂšnes codant les sous-unitĂ©s auxiliaires du canal sodium
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