Farm Consolidation in Iowa

Since World War II, census data show that the number of Iowa farms and farm operators has dropped 1,600 to 1,700 per year- depending on what is called a farm. The resulting consolidation of smaller units into larger ones is one of the major adjustment trends taking place in Corn Belt agriculture

Fractionation of human immune γ-globulin

Equine and bovine serum proteins have recently been fractionated by means of a physical method utilizing an electrophoretic adaptation of the principles of the Clusius column (l-4), first described and tested by Kirkwood (5) and Nielsen (6). The method of electrophoresis-convection has now been applied to the fractionation of human γ-globulin. The γ-globulin was prepared by ethanol fractionation (7) from the plasma of individuals hyperimmunized to Hemophilus pertussis organisms. The resulting fractions of γ-globulin have been characterized electrophoretically, and the protective antibody activity and agglutinin titer have been measured

Bone mineral density and risk of heart failure in older adults: The Cardiovascular Health Study

Background Despite increasing evidence of a common link between bone and heart health, the relationship between bone mineral density ( BMD ) and heart failure ( HF ) risk remains insufficiently studied. Methods and Results We investigated whether BMD measured by dual‐energy x‐ray absorptiometry was associated with incident HF in an older cohort. Cox models were stratified by sex and interactions of BMD with race assessed. BMD was examined at the total hip and femoral neck separately, both continuously and by World Health Organization categories. Of 1250 participants, 442 (55% women) developed HF during the median follow‐up of 10.5 years. In both black and nonblack women, neither total hip nor femoral neck BMD was significantly associated with HF ; there was no significant interaction by race. In black and nonblack men, total hip, but not femoral neck, BMD was significantly associated with HF , with evidence of an interaction by race. In nonblack men, lower total hip BMD was associated with higher HF risk (hazard ratio, 1.13 [95% CI, 1.01–1.26] per 0.1 g/cm 2 decrement), whereas in black men, lower total hip BMD was associated with lower HF risk (hazard ratio, 0.74 [95% CI, 0.59–0.94]). There were no black men with total hip osteoporosis. Among nonblack men, total hip osteoporosis was associated with higher HF risk (hazard ratio, 2.83 [95% CI, 1.39–5.74]) compared with normal BMD . Conclusions Among older adults, lower total hip BMD was associated with higher HF risk in nonblack men but lower risk in black men, with no evidence of an association in women. Further research is needed to replicate these findings and to study potential underlying pathways. </jats:sec

Live to cheat another day: bacterial dormancy facilitates the social exploitation of beta-lactamases

The breakdown of antibiotics by β-lactamases may be cooperative, since resistant cells can detoxify their environment and facilitate the growth of susceptible neighbours. However, previous studies of this phenomenon have used artificial bacterial vectors or engineered bacteria to increase the secretion of β-lactamases from cells. Here, we investigated whether a broad-spectrum β-lactamase gene carried by a naturally occurring plasmid (pCT) is cooperative under a range of conditions. In ordinary batch culture on solid media, there was little or no evidence that resistant bacteria could protect susceptible cells from ampicillin, although resistant colonies could locally detoxify this growth medium. However, when susceptible cells were inoculated at high densities, late-appearing phenotypically susceptible bacteria grew in the vicinity of resistant colonies. We infer that persisters, cells that have survived antibiotics by undergoing a period of dormancy, founded these satellite colonies. The number of persister colonies was positively correlated with the density of resistant colonies and increased as antibiotic concentrations decreased. We argue that detoxification can be cooperative under a limited range of conditions: if the toxins are bacteriostatic rather than bacteridical; or if susceptible cells invade communities after resistant bacteria; or if dormancy allows susceptible cells to avoid bactericides. Resistance and tolerance were previously thought to be independent solutions for surviving antibiotics. Here, we show that these are interacting strategies: the presence of bacteria adopting one solution can have substantial effects on the fitness of their neighbours

Visual onset expands subjective time

We report a distortion of subjective time perception in which the duration of a first interval is perceived to be longer than the succeeding interval of the same duration. The amount of time expansion depends on the onset type defining the first interval. When a stimulus appears abruptly, its duration is perceived to be longer than when it appears following a stationary array. The difference in the processing time for the stimulus onset and motion onset, measured as reaction times, agrees with the difference in time expansion. Our results suggest that initial transient responses for a visual onset serve as a temporal marker for time estimation, and a systematic change in the processing time for onsets affects perceived time

An exploration of concepts of community through a case study of UK university web production

The paper explores the inter-relation and differences between the concepts of occupational community, community of practice, online community and social network. It uses as a case study illustration the domain of UK university web site production and specifically a listserv for those involved in it. Different latent occupational communities are explored, and the potential for the listserv to help realize these as an active sense of community is considered. The listserv is not (for most participants) a tight knit community of practice, indeed it fails many criteria for an online community. It is perhaps best conceived as a loose knit network of practice, valued for information, implicit support and for the maintenance of weak ties. Through the analysis the case for using strict definitions of the theoretical concepts is made

A Deep Chandra X-ray Spectrum of the Accreting Young Star TW Hydrae

We present X-ray spectral analysis of the accreting young star TW Hydrae from a 489 ks observation using the Chandra High Energy Transmission Grating. The spectrum provides a rich set of diagnostics for electron temperature T_e, electron density N_e, hydrogen column density N_H, relative elemental abundances and velocities and reveals its source in 3 distinct regions of the stellar atmosphere: the stellar corona, the accretion shock, and a very large extended volume of warm postshock plasma. The presence of Mg XII, Si XIII, and Si XIV emission lines in the spectrum requires coronal structures at ~10 MK. Lower temperature lines (e.g., from O VIII, Ne IX, and Mg XI) formed at 2.5 MK appear more consistent with emission from an accretion shock. He-like Ne IX line ratio diagnostics indicate that T_e = 2.50 +/- 0.25 MK and N_e = 3.0 +/- 0.2 x 10^(12) cm^(-3) in the shock. These values agree well with standard magnetic accretion models. However, the Chandra observations significantly diverge from current model predictions for the postshock plasma. This gas is expected to cool radiatively, producing O VII as it flows into an increasingly dense stellar atmosphere. Surprisingly, O VII indicates N_e = 5.7 ^(+4.4}_(-1.2) x 10^(11) cm^(-3), five times lower than N_e in the accretion shock itself, and ~7 times lower than the model prediction. We estimate that the postshock region producing O VII has roughly 300 times larger volume, and 30 times more emitting mass than the shock itself. Apparently, the shocked plasma heats the surrounding stellar atmosphere to soft X-ray emitting temperatures and supplies this material to nearby large magnetic structures -- which may be closed magnetic loops or open magnetic field leading to mass outflow. (Abridged)Comment: 13 pages (emulateapj style), 10 figures, ApJ, in pres