Masses and Distances of Planetary Microlens Systems with High Angular Resolution Imaging

Microlensing is the only method that can detect and measure mass of wide orbit, low mass, solar system analog exoplanets. Mass measurements of such planets would yield massive science on planet formation, exoplanet demographics, free floating planets, planet frequencies towards the galaxy. High res follow-up observations of past microlens targets provide a mass measurement of microlens planets and hosts at an uncertainty of <20%. This will be primary method for mass measurement with WFIRST. We advocate for the fact that high resolution observations with AO, HST and JWST(in future) remain necessary in coming decade to develop the methods, to determine the field and filter selection, understand the systematics and to develop a robust pipeline to release high quality data products from WFIRST microlensing survey such that the astronomy community can promptly engage in the science. We also support future high res obs with US ELTs with advanced Laser AO systems in context of enhancing the science return of WFIRST microlensing survey. We endorse the 2018 Exoplanet Science Strategy report published by the National Academy. This white paper extends and complements the material presented therein. In particular, this white paper supports the recommendation of the National Academy Exoplanet Science Strategy report that: NASA should launch WFIRST to conduct its microlensing survey of distant planets and to demonstrate the technique of coronagraphic spectroscopy on exoplanet targets. This white paper also supports to the finding from that report which states "A number of activities, including precursor and concurrent observations using ground- and space-based facilities, would optimize the scientific yield of the WFIRST microlensing survey."Comment: 8 pages, 2 figures, Astro2020 decadal submissio

Masses and Distances of Planetary Microlens Systems with High Angular Resolution Imaging

Microlensing is the only method that can detect and measure mass of wide orbit, low mass, solar system analog exoplanets. Mass measurements of such planets would yield massive science on planet formation, exoplanet demographics, free floating planets, planet frequencies towards the galaxy. High res follow-up observations of past microlens targets provide a mass measurement of microlens planets and hosts at an uncertainty of <20%. This will be primary method for mass measurement with WFIRST. We advocate for the fact that high resolution observations with AO, HST and JWST(in future) remain necessary in coming decade to develop the methods, to determine the field and filter selection, understand the systematics and to develop a robust pipeline to release high quality data products from WFIRST microlensing survey such that the astronomy community can promptly engage in the science. We also support future high res obs with US ELTs with advanced Laser AO systems in context of enhancing the science return of WFIRST microlensing survey. We endorse the 2018 Exoplanet Science Strategy report published by the National Academy. This white paper extends and complements the material presented therein. In particular, this white paper supports the recommendation of the National Academy Exoplanet Science Strategy report that: NASA should launch WFIRST to conduct its microlensing survey of distant planets and to demonstrate the technique of coronagraphic spectroscopy on exoplanet targets. This white paper also supports to the finding from that report which states "A number of activities, including precursor and concurrent observations using ground- and space-based facilities, would optimize the scientific yield of the WFIRST microlensing survey.

The development and validation of a scoring tool to predict the operative duration of elective laparoscopic cholecystectomy

Background: The ability to accurately predict operative duration has the potential to optimise theatre efficiency and utilisation, thus reducing costs and increasing staff and patient satisfaction. With laparoscopic cholecystectomy being one of the most commonly performed procedures worldwide, a tool to predict operative duration could be extremely beneficial to healthcare organisations. Methods: Data collected from the CholeS study on patients undergoing cholecystectomy in UK and Irish hospitals between 04/2014 and 05/2014 were used to study operative duration. A multivariable binary logistic regression model was produced in order to identify significant independent predictors of long (> 90 min) operations. The resulting model was converted to a risk score, which was subsequently validated on second cohort of patients using ROC curves. Results: After exclusions, data were available for 7227 patients in the derivation (CholeS) cohort. The median operative duration was 60 min (interquartile range 45–85), with 17.7% of operations lasting longer than 90 min. Ten factors were found to be significant independent predictors of operative durations > 90 min, including ASA, age, previous surgical admissions, BMI, gallbladder wall thickness and CBD diameter. A risk score was then produced from these factors, and applied to a cohort of 2405 patients from a tertiary centre for external validation. This returned an area under the ROC curve of 0.708 (SE = 0.013, p  90 min increasing more than eightfold from 5.1 to 41.8% in the extremes of the score. Conclusion: The scoring tool produced in this study was found to be significantly predictive of long operative durations on validation in an external cohort. As such, the tool may have the potential to enable organisations to better organise theatre lists and deliver greater efficiencies in care

Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study

: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity &gt; 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others