29 research outputs found

    Of course we fly unmanned—we're women!

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    [Extract] Striving to achieve a diverse and inclusive workplace has become a major goal for many organisations around the world. We recognise that not only is it the right thing to do, but that it is proven to achieve better outcomes in terms of innovation, reativity, science, and even financial success. However, sometimes the task of change can feel overwhelming and amorphous—what steps do we need to take to reach this goal? Within the disciplines of drone technology and drone science, let us start with the first rung on the ladder: gender-neutral languag

    Characterising termite mounds in a tropical savanna with UAV laser scanning

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    Termite mounds are found over vast areas in northern Australia, delivering essential ecosystem services, such as enhancing nutrient cycling and promoting biodiversity. Currently, the detection of termite mounds over large areas requires airborne laser scanning (ALS) or high-resolution satellite data, which lack precise information on termite mound shape and size. For detailed structural measurements, we generally rely on time-consuming field assessments that can only cover a limited area. In this study, we explore if unmanned aerial vehicle (UAV)-based observations can serve as a precise and scalable tool for termite mound detection and morphological characterisation. We collected a unique data set of terrestrial laser scanning (TLS) and UAV laser scanning (UAV-LS) point clouds of a woodland savanna site in Litchfield National Park (Australia). We developed an algorithm that uses several empirical parameters for the semi-automated detection of termite mounds from UAV-LS and used the TLS data set (1 ha) for benchmarking. We detected 81% and 72% of the termite mounds in the high resolution (1800 points m−2) and low resolution (680 points m−2) UAV-LS data, respectively, resulting in an average detection of eight mounds per hectare. Additionally, we successfully extracted information about mound height and volume from the UAV-LS data. The high resolution data set resulted in more accurate estimates; however, there is a trade-off between area and detectability when choosing the required resolution for termite mound detection Our results indicate that UAV-LS data can be rapidly acquired and used to monitor and map termite mounds over relatively large areas with higher spatial detail compared to airborne and spaceborne remote sensing

    Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

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    Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline

    A review of revegetation at mine sites in the Alligator Rivers Region, Northern Territory, and the development of a state and transition model for ecological restoration at Ranger uranium mine

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    Society's expectations for mining operations are that they are undertaken using the principles of sustainable development. Numerous mines have been 'rehabilitated' in past decades without clear closure criteria or regulatory oversight and are characterised by less than desirable environmental outcomes. These sites provide us with information and data (in some instances) to inform future mine site restoration efforts and the sustainable development of mining resources. However, this information and data are often contained in inaccessible grey literature or have been lost over time. We used records and data on revegetation efforts and outcomes at mine sites in and around the Alligator Rivers Region (ARR) of the Northern Territory, Australia, to demonstrate the extent and currency of rehabilitation knowledge. There have been 20 mines in the region since 1950 and we found that these sites are in various deviated ecological states and that data for these mines were generally unavailable or unable to be located. A number of studies have been conducted at the largest operation, Ranger uranium mine, and there is also information from Nabarlek and South Alligator River Valley mines. We furthered the understanding of the system using available information to develop a preliminary state and transition model for eucalypt-dominated ecosystems in the region. The identification of likely desired and undesired ecological states and management requirements developed in this model could be used to actively guide future restoration and research efforts, particularly at Ranger uranium mine. Based on the lessons learned from the mine sites in the ARR, we provide recommendations for monitoring revegetation in the future
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