The changing residential patterns of immigrants - the case of Sweden 1973-1992

Swedish immigration policy has recently changed. The plan known as “Whole of Sweden Strategy” no longer applies, and there is greater freedom to choose where one lives. Migration is important in the redistribution of the population, and thus immigration plays a significant role. In light of this, there are good grounds for following how concentration and dispersion of immigrant groups vary, both geographically and in time

Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418

Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer's disease. We report the characterization of a GSK3 inhibitor, AR-A014418, which inhibits GSK3 (IC50 = 104 ± 27 nM), in an ATP-competitive manner (K i = 38 nM). AR-A014418 does not significantly inhibit cdk2 or cdk5 (IC50 > 100 μM) or 26 other kinases demonstrating high specificity for GSK3. We report the co-crystallization of AR-A014418 with the GSK3β protein and provide a description of the interactions within the ATP pocket, as well as an understanding of the structural basis for the selectivity of AR-A014418. AR-A014418 inhibits tau phosphorylation at a GSK3-specific site (Ser-396) in cells stably expressing human four-repeat tau protein. AR-A014418 protects N2A neuroblastoma cells against cell death mediated by inhibition of the phosphatidylinositol 3-kinase/protein kinase B survival pathway. Furthermore, AR-A014418 inhibits neurodegeneration mediated by β-amyloid peptide in hippocampal slices. AR-A014418 may thus have important applications as a tool to elucidate the role of GSK3 in cellular signaling and possibly in Alzheimer's disease. AR-A014418 is the first compound of a family of specific inhibitors of GSK3 that does not significantly inhibit closely related kinases such as cdk2 or cdk5.Supported by grants from the Comunidad de Madrid, the Fundacion “La Caixa,” the Lilly Foundation, the Spanish Comision Interministerial de Ciencia y Tecnologia, and an institutional grant from the Fundacion Ramon Areces.Peer reviewe

Tjärhanteringen i Västerbottens län under 1800-talets senare hälft : en studie av produktion och transporter med särskild hänsyn till Ume- och Vindelälvens dalgångar

Distribution: Kungl. Skytteanska Samfundet, Länsmuseet, Umeådigitalisering@um

Exempel på undervisning om judendomen i Sverige

In the Swedish branch of the International Council of Christians and Jews, called “Samarbetsrådet för judar och kristna”, the committee concerned with presentation of Judaism and Christianity in educational material for all levels, has until now mainly been looking at how Judaism is introduced in books for pupils, aged 7-12. The study has also included Barnens Bibel (The Children’s Bible) by Anne de Vries. The main question has been how Judaism is introduced to Swedish school children. Is Judaism presented in the way a Jew would like it to be presented concerning creed, life, history and the state of Israel? The study provides evidence that Judaism is mostly presented as something imperfect. Judaism is not respected in and for itself and not looked upon as an independent conception of life. Swedish ethnocentricity pervades all the material. The striving for emotional identification subdues knowledge of history. The Children’s Bible is not a simplified Bible, but a Christian interpretation of some parts of the Hebrew Bible, that prepares the children for an interpretation of the Christian Bible

Exempel på undervisning om judendomen i Sverige

In the Swedish branch of the International Council of Christians and Jews, called “Samarbetsrådet för judar och kristna”, the committee concerned with presentation of Judaism and Christianity in educational material for all levels, has until now mainly been looking at how Judaism is introduced in books for pupils, aged 7-12. The study has also included Barnens Bibel (The Children’s Bible) by Anne de Vries. The main question has been how Judaism is introduced to Swedish school children. Is Judaism presented in the way a Jew would like it to be presented concerning creed, life, history and the state of Israel? The study provides evidence that Judaism is mostly presented as something imperfect. Judaism is not respected in and for itself and not looked upon as an independent conception of life. Swedish ethnocentricity pervades all the material. The striving for emotional identification subdues knowledge of history. The Children’s Bible is not a simplified Bible, but a Christian interpretation of some parts of the Hebrew Bible, that prepares the children for an interpretation of the Christian Bible