452 research outputs found
On the Mechanism of Time--Delayed Feedback Control
The Pyragas method for controlling chaos is investigated in detail from the
experimental as well as theoretical point of view. We show by an analytical
stability analysis that the revolution around an unstable periodic orbit
governs the success of the control scheme. Our predictions concerning the
transient behaviour of the control signal are confirmed by numerical
simulations and an electronic circuit experiment.Comment: 4 pages, REVTeX, 4 eps-figures included Phys. Rev. Lett., in press
also available at
http://athene.fkp.physik.th-darmstadt.de/public/wolfram.htm
Does truth matter to voters? The effects of correcting political misinformation in an Australian sample
In the 'post-truth era', political fact-checking has become an issue of considerable significance. A recent study in the context of the 2016 US election found that fact-checks of statements by Donald Trump changed participants' beliefs about those statements-regardless of whether participants supported Trump-but not their feelings towards Trump or voting intentions. However, the study balanced corrections of inaccurate statements with an equal number of affirmations of accurate statements. Therefore, the null effect of fact-checks on participants' voting intentions and feelings may have arisen because of this artificially created balance. Moreover, Trump's statements were not contrasted with statements from an opposing politician, and Trump's perceived veracity was not measured. The present study (N = 370) examined the issue further, manipulating the ratio of corrections to affirmations, and using Australian politicians (and Australian participants) from both sides of the political spectrum. We hypothesized that fact-checks would correct beliefs and that fact-checks would affect voters' support (i.e. voting intentions, feelings and perceptions of veracity), but only when corrections outnumbered affirmations. Both hypotheses were supported, suggesting that a politician's veracity does sometimes matter to voters. The effects of fact-checking were similar on both sides of the political spectrum, suggesting little motivated reasoning in the processing of fact-checks. Keywords: voting behaviour; fact-checking; political attitudes; misconceptions; misinformation; belief chang
Restricted feedback control of one-dimensional maps
Dynamical control of biological systems is often restricted by the practical
constraint of unidirectional parameter perturbations. We show that such a
restriction introduces surprising complexity to the stability of
one-dimensional map systems and can actually improve controllability. We
present experimental cardiac control results that support these analyses.
Finally, we develop new control algorithms that exploit the structure of the
restricted-control stability zones to automatically adapt the control feedback
parameter and thereby achieve improved robustness to noise and drifting system
parameters.Comment: 29 pages, 9 embedded figure
Resonance phenomena of a solitonlike extended object in a bistable potential
We investigate the dynamics of a soliton that behaves as an extended
particle. The soliton motion in an effective bistable potential can be chaotic
in a similar way as the Duffing oscillator. We generalize the concept of
geometrical resonance to spatiotemporal systems and apply it to design a
nonfeedback mechanism of chaos control using localized perturbations.We show
the existence of solitonic stochastic resonance.Comment: 3 postscript figure
High-dimensional interior crisis in the Kuramoto-Sivashinsky equation
An investigation of interior crisis of high dimensions in an extended spatiotemporal system exemplified by the Kuramoto-Sivashinsky equation is reported. It is shown that unstable periodic orbits and their associated invariant manifolds in the Poincaré hyperplane can effectively characterize the global bifurcation dynamics of high-dimensional systems.A. C.-L. Chian, E. L. Rempel, E. E. Macau, R. R. Rosa, and F. Christianse
Point process time–frequency analysis of dynamic respiratory patterns during meditation practice
Respiratory sinus arrhythmia (RSA) is largely mediated by the autonomic nervous system through its modulating influence on the heart beats. We propose a robust algorithm for quantifying instantaneous RSA as applied to heart beat intervals and respiratory recordings under dynamic breathing patterns. The blood volume pressure-derived heart beat series (pulse intervals, PIs) are modeled as an inverse Gaussian point process, with the instantaneous mean PI modeled as a bivariate regression incorporating both past PIs and respiration values observed at the beats. A point process maximum likelihood algorithm is used to estimate the model parameters, and instantaneous RSA is estimated via a frequency domain transfer function evaluated at instantaneous respiratory frequency where high coherence between respiration and PIs is observed. The model is statistically validated using Kolmogorov–Smirnov goodness-of-fit analysis, as well as independence tests. The algorithm is applied to subjects engaged in meditative practice, with distinctive dynamics in the respiration patterns elicited as a result. The presented analysis confirms the ability of the algorithm to track important changes in cardiorespiratory interactions elicited during meditation, otherwise not evidenced in control resting states, reporting statistically significant increase in RSA gain as measured by our paradigm.National Institutes of Health (U.S.) (Grant R01-HL084502)National Institutes of Health (U.S.) (Grant R01-DA015644)National Institutes of Health (U.S.) (Grant DP1-OD003646)National Institutes of Health (U.S.) (Grant K01-AT00694-01
Mindful Aging: The Effects of Regular Brief Mindfulness Practice on Electrophysiological Markers of Cognitive and Affective Processing in Older Adults
There is growing interest in the potential benefits of mindfulness meditation practices in terms of counteracting some of the cognitive effects associated with aging. Pursuing this question, the aim of the present study was to investigate the influence of mindfulness training on executive control and emotion regulation in older adults, by means of studying behavioral and electrophysiological changes. Participants, 55 to 75 years of age, were randomly allocated to an 8-week mindful breath awareness training group or an active control group engaging in brain training exercises. Before and after the training period, participants completed an emotional-counting Stroop task, designed to measure attentional control and emotion regulation processes. Concurrently, their brain activity was measured by means of 64-channel electroencephalography. The results show that engaging in just over 10 min of mindfulness practice five times per week resulted in significant improvements in behavioral (response latency) and electrophysiological (N2 event-related potential) measures related to general task performance. Analyses of the underlying cortical sources (Variable Resolution Electromagnetic Tomography, VARETA) indicate that this N2-related effect is primarily associated with changes in the right angular gyrus and other areas of the dorsal attention network. However, the study did not find the expected specific improvements in executive control and emotion regulation, which may be due to the training instructions or the relative brevity of the intervention. Overall, the results indicate that engaging in mindfulness meditation training improves the maintenance of goal-directed visuospatial attention and may be a useful strategy for counteracting cognitive decline associated with aging
A genetic analysis of ambulatory cardiorespiratory coupling.
This study assessed the heritability of ambulatory heart period, respiratory sinus arrhythmia (RSA), and respiration rate and tested the hypothesis that the well-established correlation between these variables is determined by common genetic factors. In 780 healthy twins and siblings, 24-h ambulatory recordings of ECG and thorax impedance were made. Genetic analyses showed considerable heritability for heart period (37%-48%), RSA (40%-55%), and respiration rate (27%-81%) at all daily periods. Significant genetic correlations were found throughout. Common genes explained large portions of the covariance between heart period and RSA and between respiration rate and RSA. During the afternoon and night, the covariance between respiration rate and RSA was completely determined by common genes. This overlap in genes can be exploited to increase the power of linkage studies to detect genetic variation influencing cardiovascular disease risk. Copyright © 2005 Society for Psychophysiological Research
The role of liquid based cytology and ancillary techniques in the peritoneal washing analysis: our institutional experience
Background
The cytological analysis of peritoneal effusions serves as a diagnostic and prognostic aid for either primary or metastatic diseases. Among the different cytological preparations, liquid based cytology (LBC) represents a feasible and reliable method ensuring also the application of ancillary techniques (i.e immunocytochemistry-ICC and molecular testing).
Methods
We recorded 10348 LBC peritoneal effusions between January 2000 and December 2014. They were classified as non-diagnostic (ND), negative for malignancy-NM, atypical-suspicious for malignancy-SM and positive for malignancy-PM.
Results
The cytological diagnosis included 218 ND, 9.035 NM, 213 SM and 882 PM. A total of 8048 (7228 NM, 115SM, 705 PM) cases with histological follow-up were included. Our NM included 21 malignant and 7207 benign histological diagnoses. Our 820 SMs+PMs were diagnosed as 107 unknown malignancies (30SM and 77PM), 691 metastatic lesions (81SM and 610PM), 9 lymphomas (2SM and 7PM), 9 mesotheliomas (1SM and 8SM), 4 sarcomas (1SM and 3PM). Primary gynecological cancers contributed with 64% of the cases. We documented 97.4% sensitivity, 99.9% specificity, 98% diagnostic accuracy, 99.7% negative predictive value (NPV) and 99.7% positive predictive value (PPV). Furthermore, the morphological diagnoses were supported by either 173 conclusive ICC results or 50 molecular analyses. Specifically the molecular testing was performed for the EGFR and KRAS mutational analysis based on the previous or contemporary diagnoses of Non Small Cell Lung Cancer (NSCLC) and colon carcinomas. We identified 10 EGFR in NSCCL and 7 KRAS mutations on LBC stored material.
Conclusions
Peritoneal cytology is an adjunctive tool in the surgical management of tumors mostly gynecological cancers. LBC maximizes the application of ancillary techniques such as ICC and molecular analysis with feasible diagnostic and predictive yields also in controversial cases.info:eu-repo/semantics/publishedVersio
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