Application proposal for colombian agriculture

En este documento se realiza un análisis y verificación de aplicaciones agrícolas disponibles en Colombia, evaluando su nivel de funcionalidad y usabilidad, con el fin de realizar una propuesta de los elementos que debe de contener una aplicación para el agro, teniendo en cuenta aspectos que no se contemplan en las aplicaciones evaluadas.This document analyzes and verifies agricultural applications available in Colombia, evaluating their level of functionality and usability, in order to make a proposal of the elements that an application for agriculture should contain, taking into account aspects that are not contemplated in the evaluated applications

La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia. Municipios de Armenia, Pereira y Tolima

Con la realización del siguiente trabajo, se pretende descubrir las principales memorias que por medio de unas historias de vida han quedado plasmadas a lo largo del tiempo, dejando esa certeza de lo que fue la violencia en nuestro país por un largo periodo de tiempo, donde se evidencia ciertamente esa forma de resiliencia de muchas familias que les toco dejar sus tierras sus hogares, donde muchos murieron por una guerra desmedida y les tocó empezar de cero debido a las extorsiones a la forma como fueron acabando con su vida sin importar el daño que se les causó. De este modo se realizará un análisis del caso de Nelson un hombre que tuvo que dejar su país con su familia, debido a las extorsiones y secuestro del cual fue víctima, este caso fue elegido por los integrantes del grupo con el fin de construir una serie de preguntas reflexivas, estratégicas y circulares que se le harían a Nelson, con el fin de conocer su perspectiva en el presente, lo que sería clave para conectar con su historia y poderlo apoyar en su proceso. En un siguiente punto se realizará el análisis del caso de la masacre en el Salado un hecho de violencia que sin duda marcó la historia de los colombianos, allí el grupo realizará una reflexión de acuerdo con los ítems planteados en la guía y se propondrán unas estrategias que servirían de potenciación de los recursos de afrontamiento para los sobrevivientes de este hecho de violencia.With the realization of the following work, it is intended to discover the main memories that through life stories have been captured over time, leaving that certainty of what violence was in our country for a long period of time, where It is certainly evident that form of resilience of many families who had to leave their lands and their homes, where many died due to an excessive war and had to start from scratch due to extortion to the way in which they ended their lives regardless of the damage that they were caused In this way, an analysis of the case of Nelson will be carried out, a man who had to leave his country with his family, due to the extortion and kidnapping of which he was a victim, this case was chosen by the members of the group in order to build a series reflective, strategic and circular questions that would be asked to Nelson, in order to know his perspective in the present, which would be key to connecting with his story and being able to support him in his process. In a next point, the analysis of the case of the massacre in El Salado will be carried out, an act of violence that undoubtedly marked the history of Colombians, there the group will carry out a reflection according to the items raised in the guide and some strategies will be proposed. that would serve to empower the coping resources for the survivors of this act of violence

The Effects of Parenteral K1 Administration in Pseudoxanthoma Elasticum Patients Versus Controls. A Pilot Study

Introduction: Pseudoxanthoma elasticum (PXE) is a rare disease caused by mutations in the ABCC6 gene. Vitamin K1 is involved in the posttranslational carboxylation of some proteins related to inhibition of the calcification process. Our aim was to investigate, in patients affected by PXE, baseline levels of vitamin K1-dependent proteins and -metabolites and whether parenteral administration of phytomenadione was effective in modulating their levels. Methods: We included eight PXE patients with typical clinical symptoms (skin, retina, and vascular calcification) and two ABCC6 causative mutations; 13 clinically unaffected first-degree patients' relatives (9 carrying one ABCC6 mutation and 4 non-carriers). We assessed urinary vitamin K1 metabolites and serum Glu- and Gla-OC, Gas6 and undercaboxylated prothrombin (PIVKA-II), at baseline and after 1 and 6\u2009weeks after a single intramuscular injection of 10\u2009mg vitamin K1. Results: Comparison of PXE patients, heterozygous, and non-carriers revealed differences in baseline levels of serum MK-4 and of urinary vitamin K metabolites. The response to phytomenadione administration on vitamin K-dependent proteins was similar in all groups. Conclusion: The physiological axis between vitamin K1 and vitamin K-dependent proteins is preserved; however, differences in the concentration of vitamin K metabolites and of MK-4 suggest that vitamin K1 metabolism/catabolism could be altered in PXE patients

Plasma β-III tubulin, neurofilament light chain and glial fibrillary acidic protein are associated with neurodegeneration and progression in schizophrenia

Schizophrenia is a progressive disorder characterized by multiple psychotic relapses. After every relapse, patients may not fully recover, and this may lead to a progressive loss of functionality. Pharmacological treatment represents a key factor to minimize the biological, psychological and psychosocial impact of the disorder. The number of relapses and the duration of psychotic episodes induce a potential neuronal damage and subsequently, neurodegenerative processes. Thus, a comparative study was performed, including forty healthy controls and forty-two SZ patients divided into first-episode psychosis (FEP) and chronic SZ (CSZ) subgroups, where the CSZ sub group was subdivided by antipsychotic treatment. In order to measure the potential neuronal damage, plasma levels of β-III tubulin, neurofilament light chain (Nf-L), and glial fibrillary acidic protein (GFAP) were performed. The results revealed that the levels of these proteins were increased in the SZ group compared to the control group (P < 0.05). Moreover, multiple comparison analysis showed highly significant levels of β-III tubulin (P = 0.0002), Nf-L (P = 0.0403) and GFAP (P < 0.015) in the subgroup of CSZ clozapine-treated. In conclusion, β-III tubulin, Nf-L and GFAP proteins may be potential biomarkers of neurodegeneration and progression in SZFundação para a Ciência e a Tecnologia | Ref. SFRH/BD/135623/20Instituto de Salud Carlos III | Ref. P16/00405Ministerio de Sanidad, Igualdad y Política Social | Ref. 2017I054Agencia del Conocimiento en Salud | Ref. PRIS2-17Xunta de Galicia | Ref. IN607C-2017/02Xunta de Galicia | Ref. IN607B 2018/1

Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial

Background: Post-stroke cognitive and emotional complications are frequent in the chronic stages of stroke and have important implications for the functionality and quality of life of those affected and their caregivers. Strategies such as mindfulness meditation, physical exercise (PE), or computerized cognitive training (CCT) may benefit stroke patients by impacting neuroplasticity and brain health. Materials and methods: One hundred and forty-one chronic stroke patients are randomly allocated to receive mindfulness-based stress reduction + CCT (n = 47), multicomponent PE program + CCT (n = 47), or CCT alone (n = 47). Interventions consist of 12-week home-based programs five days per week. Before and after the interventions, we collect data from cognitive, psychological, and physical tests, blood and stool samples, and structural and functional brain scans. Results: The effects of the interventions on cognitive and emotional outcomes will be described in intention-to-treat and per-protocol analyses. We will also explore potential mediators and moderators, such as genetic, molecular, brain, demographic, and clinical factors in our per-protocol sample. Discussion: The MindFit Project is a randomized clinical trial that aims to assess the impact of mindfulness and PE combined with CCT on chronic stroke patients' cognitive and emotional wellbeing. Furthermore, our design takes a multimodal biopsychosocial approach that will generate new knowledge at multiple levels of evidence, from molecular bases to behavioral changes. Clinical trial registration: www.ClinicalTrials.gov, identifier NCT04759950

Leer en comunidad: creación y desarrollo de clubes de lectura de literatura escrita por mujeres dentro y fuera de la universidad

Depto. de Lengua Española y Teoría de la LiteraturaFac. de FilologíaFALSEsubmitte

Annual Conference on Formative Research on EFL. Practices thar inspire change.

The conference papers of the Annual Conference on Formative Research on EFL. Practices thar inspire change collect pedagogical experiences, research reports, and reflections about social issues, language teaching, teaching training, interculturality under the panorama of the Covid-19 pandemic. Each paper invites the reader to implement changes in their teaching practice through disruptive pedagogies, reflect on the social and emotional consequences of the lockdown, new paths for teacher training and different approaches for teaching interculturality. We expect to inspire new ways to train pre-service teachers and teach languages in this changing times