1,090 research outputs found

    Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells.

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    The nervous and immune systems influence each other, allowing animals to rapidly protect themselves from changes in their internal and external environment. However, the complex nature of these systems in mammals makes it difficult to determine how neuronal signaling influences the immune response. Here we show that serotonin, synthesized in Caenorhabditis elegans chemosensory neurons, modulates the immune response. Serotonin released from these cells acts, directly or indirectly, to regulate G-protein signaling in epithelial cells. Signaling in these cells is required for the immune response to infection by the natural pathogen Microbacterium nematophilum. Here we show that serotonin signaling suppresses the innate immune response and limits the rate of pathogen clearance. We show that C. elegans uses classical neurotransmitters to alter the immune response. Serotonin released from sensory neurons may function to modify the immune system in response to changes in the animal's external environment such as the availability, or quality, of food

    CamouflageFS: Increasing the Effective Key Length in Cryptographic Filesystems on the Cheap

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    One of the few quantitative metrics used to evaluate the security of a cryptographic file system is the key length of the encryption algorithm; larger key lengths correspond to higher resistance to brute force and other types of attacks. Since accepted cryptographic design principles dictate that larger key lengths also impose higher processing costs, increasing the security of a cryptographic file system also increases the overhead of the underlying cipher. We present a general approach to effectively extend the key length without imposing the concomitant processing overhead. Our scheme is to spread the ciphertext inside an artificially large file that is seemingly filled with random bits according to a key-driven spreading sequence. Our prototype implementation, CamouflageFS, offers improved performance relative to a cipher with a larger key-schedule, while providing the same security properties. We discuss our implementation (based on the Linux Ext2 file system) and present some preliminary performance results. While CamouflageFS is implemented as a stand-alone file system, its primary mechanisms can easily be integrated into existing cryptographic file systems

    The Effect of Nuclear Rotation on the Collective Transport Coefficients

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    We have examined the influence of rotation on the potential energy and the transport coefficients of the collective motion (friction and mass coefficients). For axially symmetric deformation of nucleus Th-224 we have found that at excitations corresponding to temperatures T > 1 MeV the shell correction to the liquid drop energy practically does not depend on the angular rotation. The friction and mass coefficients obtained within the linear response theory for the same nucleus at temperatures larger than T=2 MeV are rather stable with respect to rotation provided that the contributions from spurious states arising due to the violation of rotation symmetry are removed. At smaller excitations both friction and mass parameters corresponding to the elongation mode are growing functions of rotational frequency.Comment: 16 pages, 5 eps figures, Latex, submitted to Nucl.Phys.

    Phoretic Motion of Spheroidal Particles Due To Self-Generated Solute Gradients

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    We study theoretically the phoretic motion of a spheroidal particle, which generates solute gradients in the surrounding unbounded solvent via chemical reactions active on its surface in a cap-like region centered at one of the poles of the particle. We derive, within the constraints of the mapping to classical diffusio-phoresis, an analytical expression for the phoretic velocity of such an object. This allows us to analyze in detail the dependence of the velocity on the aspect ratio of the polar and the equatorial diameters of the particle and on the fraction of the particle surface contributing to the chemical reaction. The particular cases of a sphere and of an approximation for a needle-like particle, which are the most common shapes employed in experimental realizations of such self-propelled objects, are obtained from the general solution in the limits that the aspect ratio approaches one or becomes very large, respectively.Comment: 18 pages, 5 figures, to appear in European Physical Journal

    Method to compute the stress-energy tensor for the massless spin 1/2 field in a general static spherically symmetric spacetime

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    A method for computing the stress-energy tensor for the quantized, massless, spin 1/2 field in a general static spherically symmetric spacetime is presented. The field can be in a zero temperature state or a non-zero temperature thermal state. An expression for the full renormalized stress-energy tensor is derived. It consists of a sum of two tensors both of which are conserved. One tensor is written in terms of the modes of the quantized field and has zero trace. In most cases it must be computed numerically. The other tensor does not explicitly depend on the modes and has a trace equal to the trace anomaly. It can be used as an analytic approximation for the stress-energy tensor and is equivalent to other approximations that have been made for the stress-energy tensor of the massless spin 1/2 field in static spherically symmetric spacetimes.Comment: 34 pages, no figure

    Updated report on the Edinburgh - Laing wave energy device (The Duck)

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    John Laing Limited have been associated with Stephen Salter, of Edinburgh University, since the late autumn of 1978. In May 1981, at the request of ETSU, a proposal was submitted to The Wave Energy Steering Committee for updating the 1979 report. This presentation led to an Instruction to Proceed being issued by the Department of Energy in August 1981

    Determinant Representations of Correlation Functions for the Supersymmetric t-J Model

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    Working in the FF-basis provided by the factorizing FF-matrix, the scalar products of Bethe states for the supersymmetric t-J model are represented by determinants. By means of these results, we obtain determinant representations of correlation functions for the model.Comment: Latex File, 41 pages, no figure; V2: minor typos corrected, V3: This version will appear in Commun. Math. Phy

    Resonance Superfluidity: Renormalization of Resonance Scattering Theory

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    We derive a theory of superfluidity for a dilute Fermi gas that is valid when scattering resonances are present. The treatment of a resonance in many-body atomic physics requires a novel mean-field approach starting from an unconventional microscopic Hamiltonian. The mean-field equations incorporate the microscopic scattering physics, and the solutions to these equations reproduce the energy-dependent scattering properties. This theory describes the high-TcT_c behavior of the system, and predicts a value of TcT_c which is a significant fraction of the Fermi temperature. It is shown that this novel mean-field approach does not break down for typical experimental circumstances, even at detunings close to resonance. As an example of the application of our theory we investigate the feasibility for achieving superfluidity in an ultracold gas of fermionic 6^6Li.Comment: 15 pages, 10 figure

    Decomposition and nutrient release of leguminous plants in coffee agroforestry systems.

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    Leguminous plants used as green manure are an important nutrient source for coffee plantations, especially for soils with low nutrient levels. Field experiments were conducted in the Zona da Mata of Minas Gerais State, Brazil to evaluate the decomposition and nutrient release rates of four leguminous species used as green manures (Arachis pintoi, Calopogonium mucunoides, Stizolobium aterrimum and Stylosanthes guianensis) in a coffee agroforestry system under two different climate conditions. The initial N contents in plant residues varied from 25.7 to 37.0 g kg-1 and P from 2.4 to 3.0 g kg-1. The lignin/N, lignin/polyphenol and(lignin+polyphenol)/N ratios were low in all residues studied. Mass loss rates were highest in the first 15 days, when 25 % of the residues were decomposed. From 15 to 30 days, the decomposition rate decreased on both farms. On the farm in Pedra Dourada (PD), the decomposition constant k increased in the order C. mucunoides < S. aterrimum < S. guianensis < A. pintoi. On the farm in Araponga (ARA), there was no difference in the decomposition rate among leguminous plants. The N release rates varied from 0.0036 to 0.0096 d-1. Around 32 % of the total N content in the plant material was released in the first 15 days. In ARA, the N concentration in the S. aterrimum residues was always significantly higher than in the other residues. At the end of 360 days, the N released was 78 % in ARA and 89 % in PD of the initial content. Phosphorus was the most rapidly released nutrient (k values from 0.0165 to 0.0394 d-1). Residue decomposition and nutrient release did not correlate with initial residue chemistry and biochemistry, but differences in climatic conditions between the two study sites modified the decomposition rate constants

    Self-consistent model of ultracold atomic collisions and Feshbach resonances in tight harmonic traps

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    We consider the problem of cold atomic collisions in tight traps, where the absolute scattering length may be larger than the trap size. As long as the size of the trap ground state is larger than a characteristic length of the van der Waals potential, the energy eigenvalues can be computed self-consistently from the scattering amplitude for untrapped atoms. By comparing with the exact numerical eigenvalues of the trapping plus interatomic potentials, we verify that our model gives accurate eigenvalues up to milliKelvin energies for single channel s-wave scattering of 23^{23}Na atoms in an isotropic harmonic trap, even when outside the Wigner threshold regime. Our model works also for multi-channel scattering, where the scattering length can be made large due to a magnetically tunable Feshbach resonance.Comment: 7 pages, 4 figures (PostScript), submitted to Physical Review
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