Critical drivers for the adoption of wearable sensing technologies (WSTs) for construction safety monitoring in Ghana: A Fuzzy Synthetic Analysis

Purpose: The construction industry is one of the most hazardous working environments globally. Studies reveal that wearable sensing technologies (WSTs) have practical applications in construction occupational health and safety management. In the global south, the adoption of WSTs in construction has been slow with few studies investigating the critical drivers for its adoption. The study therefore bridges this gap by investigating the factors driving WSTs adoption in Ghana where investments in such technologies can massively enhance health and safety through effective safety monitoring. Design/Methodology: To meet the objectives of this study, research data was drawn from 210 construction professionals. Purposive sampling technique was used to select construction professionals in Ghana and data was collected with the use of well-structured questionnaires. The study adopted the Fuzzy Synthetic Evaluation Model (FSEM) to determine the significance of the critical drivers for the adoption of WSTs. Findings: According to the findings, perceived value, technical know-how, security, top management support, competitive pressure, and trading partner readiness obtained a high model index of 4.154, 4.079, 3.895, 3.953, 3.971, and 3.969, respectively, as critical drivers for WSTs adoption in Ghana. Among the three broad factors, technological factors recorded the highest index of 3.971, followed by environmental factors and organizational factors with a model index of 3.938 and 3.916 respectively. Implications: Theoretically, findings are consistent with studies conducted in developed countries, particularly with regard to the perceived value of WSTs as a key driver in its adoption in the construction industry. This study also contributes to the subject of WSTs adoption and, in the case of emerging countries. Practically, findings from the study can be useful to technology developers in planning strategies to promote WSTs in the global south. To enhance construction health and safety in Ghana, policymakers can draw from the findings to create conducive conditions for worker acceptance of WSTs. Originality/Value: Studies investigating the driving factors for WSTs adoption have mainly centered on developed countries. This study addresses this subject in Ghana where studies on WSTs application in construction process is uncommon. It also uniquely explores the critical drivers for WSTs adoption using the Fuzzy Synthetic Evaluation Model

Prevalence of plant-parasitic nematodes associated with tomatoes in three agro-ecological zones of Ghana

A study was conducted between August 2014 and May 2015 to identify plant-parasitic nematodes taxa associated with tomato (Solanum lycopersicum L.) and to assess the knowledge, perceptions and experiences of growers of the crop on occurrence and management of the parasites on their farms in nine communities within the semi-deciduous forest, the forest/savanna transitional and the savanna agro-ecological zones of Ghana. Semi-structured questionnaires were designed and administered to 54 randomly selected growers from the nine communities. Composite rhizosphere soil and tomato root samples were collected from two farms in each of the nine communities, and nematodes extracted, identified and recorded. The study revealed that many growers (73%) could not distinguish between nematode infestation, nutrient deficiency and moisture stress and, therefore, lacked knowledge on nematode control. Most of the growers (63%) continually cropped their land to tomato for periods of 4 –7 years without fallowing. All growers applied only inorganic fertilizer to their crops. Symptoms of nematode infestation were widespread in fields with high yield losses. Tomato was a host to Helicotylenchus spp. (11.5% in soil), Hoplolaimus spp. (1.0 % in soil), Meloidogyne spp. (37.4% in soil and 69.3% in roots), Pratylenchus spp. (20.6% in soil and 13.7% in roots), Rotylenchulus spp. (11.0% in soil and 12.2% in roots), Scutellonema spp. (9.5% in soil and 4.9% in roots), Tylenchus spp.(7.6% in soil) and Xiphinema spp.(1.4% in soil) across the nine communities surveyed. Semi-deciduous forest and Savanna agro-ecological zones had the highest and least population densities of nematodes, respectively. These nematodes, if not managed efficiently, could also serve as constraint to tomato production in the country

Efficiency of common washing treatments in reducing microbial levels on lettuce in Mali

Lettuce is one of the most cultivated vegetables (eaten raw) in Mali with a percentage of 69.4 amongst leafy vegetables and 30.4 of all vegetables. Vegetables consumed raw, particularly lettuce, are sources of foodborne pathogens. This study was conducted to assess bacterial contamination of unwashed lettuce and the efficiency of disinfecting it with tap water and varying concentrations of some chemical disinfectants: bleach (0.00285, 0.00570 and 0.00855 ppm), potassium permanganate (170, 340 and 510 ppm), vinegar (0.00285, 0.00570 and 0.00855 ppm) and common salt (500, 1000 and 1500 ppm) based on the three consecutive washing protocol recommended for vegetables in Mali. Lettuce samples were randomly selected from farms irrigated with untreated river water within communities five and six in Bamako. Lettuce leaves were exposed to low concentration of the chemical disinfectants at 15 min, intermediate at 10 min and high at 5 min. A bleach (0.00285 ppm)/vinegar (0.00285 ppm) combination disinfection was also tested at 15 min. Tap water, bleach, potassium permanganate, vinegar and common salt reduced faecal coliform populations by 1.3–2.9, 1.5–3.0 and 1.9–3.5 log CFU/100 g, at 5, 10 and 15 min, respectively. Disinfection treatment using bleach (0.00285 ppm) was found to be more effective than other disinfectants at all contact times. All the disinfectants reduced Escherichia coli populations by 2.0–2.8 log CFU/100 g on lettuce and completely eliminated Salmonella spp. at all treatment contact times. Disinfection treatment using bleach/vinegar combination at 15 min also reduced faecal coliform populations on lettuce by 2.8 log CFU/100 g and completely eliminated E. coli and Salmonella spp. All chemical disinfectants including tap water at 15 min reduced faecal coliform populations below the undesirable ICMSF (2011) level (1000 CFU/100 g wet weight). These could contribute to reduce the health risk associated with the consumption of lettuce in Mali

Antimicrobial effects of liquid anesthetic isoflurane on Candida albicans

Candida albicans is a dimorphic fungus that can grow in yeast morphology or hyphal form depending on the surrounding environment. This ubiquitous fungus is present in skin and mucus membranes as a potential pathogen that under opportunistic conditions causes a series of systemic and superficial infections known as candidiasis, moniliasis or simply candidiasis. There has been a steady increase in the prevalence of candidiasis that is expressed in more virulent forms of infection. Although candidiasis is commonly manifested as mucocutaneous disease, life-threatening systemic invasion by this fungus can occur in every part of the body. The severity of candidal infections is associated with its morphological shift such that the hyphal morphology of the fungus is most invasive. Of importance, aberrant multiplication of Candida yeast is also associated with the pathogenesis of certain mucosal diseases. In this study, we assessed the anti-candidal activity of the volatile anesthetic isoflurane in liquid form in comparison with the anti-fungal agent amphotericin B in an in vitro culture system. Exposure of C. albicans to isoflurane (0.3% volume/volume and above) inhibited multiplication of yeast as well as formation of hyphae. These data suggest development of potential topical application of isoflurane for controlling a series of cutaneous and genital infections associated with this fungus. Elucidiation of the mechanism by which isoflurane effects fungal growth could offer therapeutic potential for certain systemic fungal infections

Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector

African malaria mosquitoes (Anopheles gambiae sensu stricto) transmit a malaria parasite (Plasmodium falciparum) to humans. The current control strategies for the vector have mainly focussed on synthetic products, which negatively impact the environment and human health. Given the potential use of environmentally friendly plant-derived volatiles as a control, this work aims to examine and compare the repellency potential of essential oils and headspace volatiles from Ocimum gratissimum, Ocimum tenuiflorum, and Ocimum basilicum and their chemical compositions. The repellency potential and chemical composition of the plants were achieved by using the protected arm-in-cage method and gas chromatography-mass spectrometry (GC-MS) analysis. Among the three Ocimum species, both the essential oils and the headspace volatiles from O. tenuiflorum achieved the longest repellency time lengths of 90–120 minutes. One hundred and one (101) chemical constituents were identified in the headspace volatiles of the three Ocimum spp. Nonetheless, (−)-camphor, (E)-γ-bisabolene, terpinolene, β-chamigrene, cubedol, (E)-farnesol, germacrene D-4-ol, viridiflorol, γ-eudesmol, tetracyclo [6.3.2.0 (2,5).0(1,8)] tridecan-9-ol, 4,4-dimethyl, α-eudesmol, isolongifolol, and endo-borneol were unique only to O. tenuiflorum headspace volatiles. Either essential oils or headspace volatiles from O. tenuiflorum could offer longer protection time length to humans against An. gambiae. Though field studies are needed to assess the complementarity between the chemical constituents in the headspace volatiles of O. tenuiflorum, our observations provide a foundation for developing effective repellents against An. gambiae

Genetic analysis of heterogeneous subsets of circulating tumour cells from high grade serous ovarian carcinoma patients

Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the tumour of origin. They bear specific intra- and extra-cellular protein markers aiding in their detection. However, since these markers may be shared with other rare cells in the blood, only genetic testing can confirm their malignancy. Herein, we analyse different CTC subsets using single cell whole genome DNA sequencing to validate their malignant origin. We randomly selected putative CTCs identified by immunostaining that were isolated from 4 patients with high grade serous ovarian cancer (HGSOC) and one with benign cystadenoma. We specifically targeted CTCs positive for epithelial (CK/EpCAMpos), mesenchymal (vimentinpos), and pseudoendothelial (CK/EpCAMpos plus CD31pos) markers. We isolated these cells and performed whole genome amplification (WGA) and low-pass whole-genome sequencing (LP-WGS) for analysis of copy number alterations (CNA). Of the CK/EpCAMpos cells analysed from the HGSOC patients, 2 of 3 cells showed diverse chromosomal CNAs. However, the 4 pseudoendothelial cells (CK/EpCAMpos plus CD31pos) observed in the HGSOC cases did not carry any CNA. Lastly, two of the clusters of vimentin positive cells sequenced from those found in the benign cystadenoma case had CNA. Despite the low number of cells analysed, our results underscore the importance of genetic analysis of putative CTCs to confirm their neoplastic origin. In particular, it highlights the presence of a population of CK/EpCAMpos cells that are not tumour cells in patients with HGSOC, which otherwise would be counted as CTCs

Adherence to antiretroviral therapy among HIV patients in Ghana: a systematic review and meta-analysis

Maintaining a high level of adherence to antiretroviral therapy (ART) is critical to limiting rapid viral replication, drug resistance, and viral transmission. However, ART adherence remains a major challenge in HIV/AIDS treatment success. This systematic review and meta-analysis was aimed to synthesize available evidence on adherence to ART among HIV/AIDS patients in Ghana.This review followed the preferred reporting item for systematic review and meta-analysis (PRISMA) criteria. A comprehensive literature search was done using five online databases (PubMed, Google Scholar, Medline, Africa Index Medicus, and Willey Online Library) from 25th- 30th April 2023 to identify potential studies. In addition, references of related articles were manually searched to further identify relevant studies. Search records were managed in Endnote library where duplicates were removed prior to screening. Studies were eligible for inclusion if they were conducted in Ghana, designed as an observational or experimental study, and explicitly measured adherence to ART, either as a primary or secondary outcome. Studies were excluded if the proportion or prevalence of adherence to ART was not reported.A total number of 126 potential studies were identified from the literature search. Of these, 14 met the inclusion criteria and were included in the Meta-analysis. The studies involved a total number of 4,436 participants. The pooled estimate of adherence to ART was 70% (CI: 58–81%). In subgroup analysis, adolescents and young adults had a lower adherence rate (66%, CI: 46–84%) compared with adults (70%; CI: 58–81%). Publication bias was not observed among studies. The pooled estimate of optimal adherence to ART among HIV patients in Ghana was lower than is recommended (≥95%) to achieve viral suppression. Adherence was lower among young persons living with HIV/AIDS. To achieve the United Nation’s Sustainable development goals and the UNAIDS “95-95-95” targets, there is a need to focus on improving adherence interventions among persons living with HIV/AIDS, especially among the younger cohort

FARMERS' ACCESSIBILITY AND USE OF HYBRID COCOA SEEDLINGS FOR COCOA REHABILITATION: EMPIRICAL RESULTS FROM AMENFI CENTRAL DISTRICT, GHANA

The introduction of hybrid seedlings of cocoa by the Ghana Cocoa Board (COCOBOD) was intended to replace old and diseased trees which were less productive. We conducted a study to investigate the accessibility and use of hybrid cocoa seedlings (Series II, the Modified Series II, Inter Amazon, Trinitario, Clones, Criollo and Nacional) for the cocoa rehabilitation exercise. Working with 385 cocoa farmers selected from the Amenfi Central District using the multi-stage sampling technique, we analyzed the data with statistical tools such as the mean, standard deviation, frequency, percentage, multiple linear regression and chi-square test of independence. Based on the general perception of the cocoa farmers (PI=3.71), we found that they had positive perceptions of the improved hybrid cocoa seedlings. Cocoa farmers’ access to all the hybrid cocoa seedlings is significantly associated with their use (P<0.05). We also found that cocoa farmers who were highly experienced and had small farm sizes had more access to and used hybrid cocoa seedlings (P<0.05). While, access to labour and ownership of lands had influence on access to hybrid cocoa seedlings (P<0.05), high yields and membership of cooperatives had influence on the use of hybrid cocoa seedlings (P<0.05). The lack of access to credit is indicated by farmers as their most severe challenge in accessing and using hybrid seedlings. The outcome of the study suggests that the cost of the hybrid seedlings must be subsidized and the distribution of the seedlings must be done through the farmer cooperatives to enhance accessibility and use

Cooking and Meal Planning as Predictors of Fruit and Vegetable Intake and BMI in First-Year College Students

The objective was to determine if cooking skills and meal planning behaviors are associated with greater fruit and vegetable intake and lower body mass index (BMI) in first-year college students who are at risk for excessive weight gain. A cross-sectional analysis was conducted using baseline data from a multi-state research project aimed at preventing weight gain in first-year college students. Cooking type, frequency and confidence, self-instruction for healthful mealtime behavior intention, self-regulation of healthful mealtime behavior, and cup equivalents of fruits and vegetables (FV) were measured using validated surveys. BMI was calculated from measured height and weight. First-year students (n = 1108) considered at risk for weight gain from eight universities completed baseline assessments within the first month of entering college. Multiple linear regression was used to determine associations among independent variables of cooking patterns, meal planning behaviors, and dependent variables of fruit and vegetable intake and BMI, after controlling for the influence of sex. Cooking more frequently, cooking with greater skills, and practicing meal planning behaviors are associated with greater fruit and vegetable intake and lower BMI in first-year college students. Interventions aimed at improving health in college students may be enhanced by incorporating cooking and meal planning components