A Study Towards Spanish Abstract Meaning Representation

Taking into account the increasing attention that researchers of Natural Language Understanding (NLU) and Natural Language Generation (NLG) are paying to Computational Semantics, we analyze the feasibility of annotating Spanish Abstract Meaning Representations. The Abstract Meaning Representation (AMR) project aims to create a large- scale sembank of simple structures that represent unified, complete semantic information contained in English sentences. Although AMR is not destined to be an interlingua, one of its key features is the ability to focus on events rather than on word forms. They do this, for instance, by abstracting away from morpho-syntactic idiosyncrasies. In this thesis, we investigate the requirements to – and we come up with a proposal to – annotate Spanish AMRs, based on the premise that many of these idiosyncrasies mark differences between languages. To our knowledge, this is the first work towards the development of Abstract Meaning Representation for Spanish

Generalization of the kappa coeficient for ordinal categorical data, multiple observers and incomplete designs

This paper presents a generalization of the kappa coefficient for multiple observers and incomplete designs. This generalization involves ordinal categorical data and includes weights which permit pondering the severity of disagreement. A generalization for incomplete designs of the kappa coefficient based on explicit definitions of agreement is also proposed. Both generalizations are illustrated with data from a medical diagnosis pilot study

Immunostaining for Homer reveals the majority of excitatory synapses in laminae I-III of the mouse spinal dorsal horn

The spinal dorsal horn processes somatosensory information before conveying it to the brain. The neuronal organization of the dorsal horn is still poorly understood, although recent studies have defined several distinct populations among the interneurons, which account for most of its constituent neurons. All primary afferents, and the great majority of neurons in laminae I–III are glutamatergic, and a major factor limiting our understanding of the synaptic circuitry has been the difficulty in identifying glutamatergic synapses with light microscopy. Although there are numerous potential targets for antibodies, these are difficult to visualize with immunocytochemistry, because of protein cross-linking following tissue fixation. Although this can be overcome by antigen retrieval methods, these lead to difficulty in detecting other antigens. The aim of this study was to test whether the postsynaptic protein Homer can be used to reveal glutamatergic synapses in the dorsal horn. Immunostaining for Homer gave punctate labeling when viewed by confocal microscopy, and this was restricted to synapses at the ultrastructural level. We found that Homer puncta were colocalized with the AMPA receptor GluR2 subunit, but not with the inhibitory synapse-associated protein gephyrin. We also examined several populations of glutamatergic axons and found that the great majority of boutons were in contact with at least one Homer punctum. These results suggest that Homer antibodies can be used to reveal the great majority of glutamatergic synapses without antigen retrieval. This will be of considerable value in tracing synaptic circuits, and also in investigating plasticity of glutamatergic synapses in pain states

Generalization of the kappa coeficient for ordinal categorical data, multiple observers and incomplete designs

This paper presents a generalization of the kappa coefficient for multiple observers and incomplete designs. This generalization involves ordinal categorical data and includes weights which permit pondering the severity of disagreement. A generalization for incomplete designs of the kappa coefficient based on explicit definitions of agreement is also proposed. Both generalizations are illustrated with data from a medical diagnosis pilot study

Evaluación formativa de un programa para la enseñanza las matemáticas a alumnos de magisterio

El propósito de este artículo es difundir los resultados de una investigación basada en el uso de la evaluación formativa realizada con futuros maestros de educación primaria en el área de matemáticas. Concluimos que la evaluación formativa de estudiantes es una parte eficaz del proceso de enseñanza

A Study Towards Spanish Abstract Meaning Representation

Taking into account the increasing attention that researchers of Natural Language Understanding (NLU) and Natural Language Generation (NLG) are paying to Computational Semantics, we analyze the feasibility of annotating Spanish Abstract Meaning Representations. The Abstract Meaning Representation (AMR) project aims to create a large- scale sembank of simple structures that represent unified, complete semantic information contained in English sentences. Although AMR is not destined to be an interlingua, one of its key features is the ability to focus on events rather than on word forms. They do this, for instance, by abstracting away from morpho-syntactic idiosyncrasies. In this thesis, we investigate the requirements to – and we come up with a proposal to – annotate Spanish AMRs, based on the premise that many of these idiosyncrasies mark differences between languages. To our knowledge, this is the first work towards the development of Abstract Meaning Representation for Spanish

Relevance of new therapies in the current treatment of adult penile curvature (Peyronie's disease)

RESUMEN: Introducción: La Enfermedad de Peyronie (EP) condiciona la actividad sexual reduciendo la calidad de vida de los pacientes. En su fase crónica, los únicos tratamientos con evidencia son la cirugía y el tratamiento intralesional con Colagenasa de Clostridium Histolyticum (CCH). Objetivo: Evaluar la efectividad y seguridad del uso en situación de práctica clínica habitual de CCH y su comparación indirecta con el tratamiento quirúrgico. Material y métodos: Estudio de cohortes retrospectivo de pacientes con EP en fase estable candidatos a tratamiento con CCH o cirugía, entre ene/2016 y dic/2018 en un hospital de tercer nivel. Análisis descriptivo y estadístico empleando como variable principal de eficacia los grados de disminución de la curvatura peneana. Como variable de seguridad se registraron los eventos adversos relacionados con el tratamiento (EART). Resultados: Se incluyeron 61 pacientes: 35 candidatos a CCH y 26 a tratamiento quirúrgico. La curvatura se redujo -16,45⁰ ( IC 95% -21,19 - -11,71) con CCH y -46,87⁰ ( IC 95% -56,42 - -37,33) tras cirugía. Se registraron 4 EART graves (hematomas), 3 tras CCH y 1 tras cirugía. Conclusión: El tratamiento con CCH es efectivo y seguro en condiciones de práctica clínica habitual permitiendo ampliar las opciones de tratamiento activo en pacientes con EP.ABSTRACT: Introduction: Peyronie's disease (PD) impairs sexual activity reducing patient´s quality of life. In its chronic phase, the only treatments with evidence are surgery and local treatment with Collagenase of Clostridium Histolyticum (CCH). Purpose: To evaluate the effectiveness and safety of the use of CCH in clinical practice and its indirect comparison with surgical treatment. Material and methods: Retrospective cohort study of patients with stable phase PE selected to receive treatment with CCH or surgery, between Jan/2016 and Dec/2018 in a tertiary referral center. Descriptive and statistical analysis using degree of reduction of penile curvature as the main variable of effectiveness. As safety variable, adverse events related to treatment (AERT) were recorded. Results: 61 patients were included: 35 candidates for CCH and 26 for surgical treatment. The curvature was reduced -16.45⁰ (95% CI -21.19 - -11.71) with CCH and -46.87⁰ (95% CI -56.42 - -37.33) after surgery. There were 4 severe EART (hematoma), 3 after CCH and 1 after surgery. Conclusion: The treatment with CCH is effective and safe under conditions of usual clinical practice allowing to expand the options of active treatment in patients with PD.Grado en Medicin

Evaluación formativa de un programa para la enseñanza las matemáticas a alumnos de magisterio

The purpose of this paper is to publish the results of a formative syllabus research carried out among future primary school teachers in the subject area of mathematics. We conclude that the formative assessment of pupils is an effective part of the teaching process.El propósito de este artículo es difundir los resultados de una investigación basada en el uso de la evaluación formativa realizada con futuros maestros de Educación Primaria en el área de matemáticas. Concluimos que la evaluación formativa de estudiantes es una parte eficaz del proceso de enseñanza

La enseñanza con ordenador y errores de aprendizaje: el caso de la estadística

Ante la necesidad de hacer la «réplica» al trabajo La construcción del significado de la asociación (AS) mediante actividades de análisis de datos: reflexiones sobre el papel del ordenador en la enseñanza de la estadística, aprendizaje de estadística, la primera pregunta que me planteé fue ¿qué es una réplica? Según el Diccionario de la Lengua Española “replicar es instar, o argüir contra la respuesta o argumento”. Luego, tomando como modelo el trabajo de Lesh25 y siguiendo la estructura del Primer Simposio de la SEIEM, se entiende que yo debo presentar una reacción o crítica al trabajo citado. Pues bien, en torno a la construcción del significado de la AS, yo no tengo nada nuevo que decir que no pueda encontrarse en las referencias citadas por los autores. Por eso, haré, simplemente, una descripción de los problemas que me surgieron al leer el texto y un análisis de las conclusiones desde mis propios conocimientos y experiencia y de discusiones mantenidas con otros profesores, tanto ajenos al tema como con experiencia en el uso de ordenador