Octupole correlations near 110Te

The lifetime of the 2+ and 9-, 11-, 13-, 15- states in the neutron-deficient 110Te was measured for the first time using the recoil distance Doppler shift technique. The reported value of the reduced transition probability B(E2;0+g.s?2+)=4.3(8)×103e2fm4 supports the systematic for even-mass Te isotopes and was interpreted in the framework of the large-scale shell model and cranked shell model calculations. The measured reduced transition probabilities in the negative-parity yrast band revealed the upward trend towards the high spins. The enhanced collectivity is discussed in terms of the tilted axis cranking approach and the symmetry configuration mixing method with the Gogny D1S interaction.The authors would like to thank the technical staff of the LNL Legnaro facility for their assistance in providing excellent operation of the XTU-tandem accelerator. The authors wish to acknowledge the support of local engineers P. Cocconi and R. Isocrate. The work was partially supported by the DoE Grant No. DE-FG02-95ER4093 and Spanish MICINN Grant No. PGC2018-094583-B-I00

System Virtualization Tools for Software Development

The configuration complexity of preproduction sites coupled with access-control mechanisms often impede the software development life cycle. Virtualization is a cost-effective way to remove such barriers and provide a test environment similar to the production site, reducing the burden in IT administrators. An Eclipse-based virtualization tool framework can offer developers a personal runtime environment for launching and testing their applications. The authors have followed a model-driven architecture (MDA) approach that integrates best-of-breed virtualization technologies, such as Xen and VDE.ITECBAN is an IT innovation project partially funded by CENIT (a Spanish public R&D program). We're grateful to MITYC (Ministerio de Industria, Turismo y Comercio) and CDTI (Centro para el Desarrollo Tecnológico e Industrial) for supporting ITECBAN through CENIT

Isospin diffusion from 40,48Ca + 40,48Ca experimental data at Fermi energies: Direct comparisons with transport model calculations

This article presents an investigation of isospin equilibration in cross-bombarding 40,48 Ca + 40,48 Ca reactions at 35 MeV/nucleon, by comparing experimental data with filtered transport model calculations. Isospin diffusion is studied using the evolution of the isospin transport ratio with centrality. The asymmetry parameter δ = (N − Z )/A of the quasiprojectile (QP) residue is used as isospin-sensitive observable, while a recent method for impact parameter reconstruction is used for centrality sorting. A benchmark of global observables is proposed to assess the relevance of the antisymmetrized molecular dynamics (AMD) model, coupled to GEMINI++, in the study of dissipative collisions. Our results demonstrate the importance of considering cluster formation to reproduce observables used for isospin transport and centrality studies. Within the AMD model, we prove the applicability of the impact parameter reconstruction method, enabling a direct comparison to the experimental data for the investigation of isospin diffusion. For both, we evidence a tendency to isospin equilibration with an impact parameter decreasing from 9 to 3 fm, while the full equilibration is not reached. A weak sensitivity to the stiffness of the equation of state employed in the model is also observed, with a better reproduction of the experimental trend for the neutron-rich reactions.Departamento de Física Aplicad

Observation and Spectroscopy of New Proton-Unbound Isotopes 30Ar and 29Cl: An Interplay of Prompt Two-Proton and Sequential Decay

Previously unknown isotopes Ar30 and Cl29 have been identified by measurement of the trajectories of their in-flight decay products S28+p+p and S28+p, respectively. The analysis of angular correlations of the fragments provided information on decay energies and the structure of the parent states. The ground states of Ar30 and Cl29 were found at 2.25+0.15−0.10 and 1.8±0.1  MeV above the two- and one-proton thresholds, respectively. The lowest states in Ar30 and Cl29 point to a violation of isobaric symmetry in the structure of these unbound nuclei. The two-proton decay has been identified in a transition region between simultaneous two-proton and sequential proton emissions from the Ar30 ground state, which is characterized by an interplay of three-body and two-body decay mechanisms. The first hint of a fine structure of the two-proton decay of Ar∗30(2+) has been obtained by detecting two decay branches into the ground and first-excited states of the S28 fragment.A. G., S. K., S. R., and P. S. were supported by the Helmholtz Association Grant No. IK-RU-002. L. V. G. was partly supported by the Ministry of Education and Science of the Russian Federation Grant No. NSh- 932.2014.2. A. F., A. G., L. V. G., S. K., P. S., and R. S. were partly supported by the Russian Foundation for Basic Research Grant No. 14-02-00090-a. This work was partly supported by the Polish National Science Center under Contract No. UMO-2011/01/B/ST2/01943. A. A. C. acknowledges support by the Polish Ministry of Science and Higher Education by Grant No. 0079/DIA/ 2014/43 (Grant Diamentowy). M. P. and X. X. are grateful for a support from the Helmholtz International Center for FAIR (HIC for FAIR). Y. L. was supported by the Helmholtz-CAS Joint Research Group Grant No. HCJRG- 108. J. M. E. acknowledges support from the FPA2009- 08848 contract (MICINN, Spain

Search for the γ decay of the narrow near-threshold proton resonance in 11B

The γ decay of the elusive narrow, near-threshold proton resonance in 11B was investigated at Laboratori Nazionali di Legnaro (INFN) in a particle-γ coincidence experiment, using the 6Li(6Li,pγ) fusion-evaporation reaction and the GALILEO-GALTRACE setup. No clear signature was found for a possible E1 decay to the 1/2 , first-excited state of 11B, predicted by the Shell Model Embedded in the Continuum (SMEC) with a branching of with respect to the dominant particle-decaying modes. The statistical analysis of the γ-ray spectrum provided an average upper limit of for this γ-ray branching, with a global significance of 5σ. On the other hand, by imposing a global confidence level of 3σ, a significant excess of counts was observed for E keV, corresponding to a resonance energy of 11429(20) keV (namely 200(20) keV above the proton separation energy of 11B) and a γ-ray branching of . This result is compatible with the SMEC calculations, potentially supporting the existence of a near-threshold proton resonance in 11B.This work was supported by the Italian Istituto Nazionale di Fisica Nucleare, the Polish National Science Centre, Poland under research project No. 2020/39/D/ST2/03443 , the PRIN2017 call for funding, under the project 2017P8KMFT CTADIR from the Italian Ministry of Education, University and Research, the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, grant no. 2020R1A6A3A03039081 , the MCIN/AEI/10.13039/501100011033, Spain with grant PID2020-118265GB-C42 , by Generalitat Valenciana, Spain with grant CIAPOS/2021/114 and by the EU FEDER funds.Departamento de Física Aplicad

Isospin diffusion measurement from the direct detection of a Quasi-Projectile remnant

The neutron-proton (n-p) equilibration process in 48Ca+40Ca at 35 MeV/nucleon bombarding energy is experimentally estimated by means of the isospin transport ratio. Experimental data are collected with a subset of the FAZIA telescope array, which permits us to determine the Z and N of detected fragments. For the first time, the quasiprojectile (QP) evaporative channel is compared with the QP breakup one in a homogeneous and consistent way, pointing to comparable n-p equilibration, which suggests a close interaction time between projectile and target independently of the exit channel. Moreover, in the QP evaporative channel n-p equilibration is compared with the prediction of the antisymmetrized molecular dynamics model coupled with the GEMINI statistical model as an afterburner, showing a higher probability of proton and neutron transfers in the simulation with respect to the experimental data.This work required the use of a lot of computation time for the production of the simulated data. We would like to thank the GARR Consortium for the kind use of the cloud computing infrastructure on the platform cloud.garr.it. We would like to thank also the INFN-CNAF for the use of its cloud computing infrastructure. A. Ono was supported by JSPS KAK-ENHI Grant No. JP17K05432. This work was also supported by the National Research Foundation of Korea (NRF)(Grant No. 2018R1A5A1025563).Departamento de Física Aplicad

Routine management of locally advanced cervical cancer with concurrent radiation and cisplatin. Five-year results

BACKGROUND: Globally, cervical cancer primarily affects socially disadvantaged women. Five randomized trials were the foundation for adopting cisplatin-based chemotherapy during radiation as the standard of care for high-risk patients after primary radical hysterectomy who require adjuvant radiation and for locally advanced patients treated with definitive radiation. These results were obtained in clinical trials performed in carefully prepared academic centers; hence, we sought to determine whether these results could be reproduced when patients were treated on an out-of-protocol basis. METHODS: We reviewed the files of 294 patients with locally advanced cervical cancer who received radiation plus weekly cisplatin as routine management between 1999 to 2003, and analyzed treatment compliance, response rate, toxicity, and survival. RESULTS: A total of 294 patients who received radiation and cisplatin were analyzed. Mean age was 43.8 years (range, 26–68 years). The majority of cases were squamous cell carcinoma (87.8%), and distribution according to International Federation of Gynecology and Obstetrics (FIGO) stage was as follows: IB2-IIA, 23%; IIB, 53.3%, and IIIB, 23%; there were only two IVA cases. Overall, 96% of patients completed external beam, and intracavitary therapy. The majority of patients (67%) received the planned six courses of weekly cisplatin. Complete responses were achieved in 243 (83%) patients, whereas 51 (17%) had either persistent (32 patients, 10.8%) or progressive (19 patients, 6.4%) disease. At median follow-up (28 months; range, 2–68 months), 36 patients (12.2%) have relapsed (locally 30.5, and systemically, 69.5%). The most common toxicities were hematologic and gastrointestinal, in the majority of cases considered mild-moderate. At median follow-up (28 months; range, 2–68 months), overall and progression-free survival are 76.5 and 67%, respectively. CONCLUSION: Our results support use of chemoradiation with six weekly applications of cisplatin at 40 mg/m(2 )during external radiation for routine management of locally advanced cervical cancer

Effect of the use of videos in the pre-class preparation of laboratory sessions taught by flip teaching

[EN] Nowadays, it is well stablished the effectiveness of flip teaching in different areas. Video is widely used as a pre-class learning material and it is progressively replacing text-document materials. The students, 70 in total, are enrolled in the laboratory practice of the subject of Physics (Bachelor¿s Degree: Industrial Electronics and Automation Engineering) at the Universitat Politècnica de València. Student¿s perception data were collected from the results of a survey. Students were asked about the usefulness of the videos and the in-class work, paying special attention to the roll of the instructor in relation to the flip teaching methodology and the pre-class material. The students were divided into two groups. In one of them, the videos were recorded by the same instructor present at the lab session, whereas the other group, the videos used were recorded by instructors different from the instructor present at the lab. The results indicate that students feel that the videos are very useful, rather than the written documents. They attribute a high value to the instructor in the lab session as they feel more confident with their work and they can ask for help when needed. They value positively the possibility of work autonomously. Small differences have been found in the opinion of both groups being the higher in the question that concerns the preference of the videos respect to the text.This work has been supported by the Universitat Politècnica de València through the Project of Innovation and Educational Improvement Program (Projects PIME/2018/B26 and PIME/2018/B25 Convocatoria de Proyectos de Innovación y Convergencia).Meseguer Dueñas, JM.; Quiles Casado, SDLS.; Sabater I Serra, R.; Serrano, M.; Gómez-Tejedor, J.; García-Sánchez, TM.; Tort-Ausina, I.... (2020). Effect of the use of videos in the pre-class preparation of laboratory sessions taught by flip teaching. Iated. 6107-6112. https://doi.org/10.21125/inted.2020.1654S6107611

Review of concepts in therapeutic decision-making in HER2-negative luminal metastatic breast cancer

Purpose: Hormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormone therapy (HT). As consensus documents are valuable tools that assist in the decision-making process for establishing clinical strategies and optimize the delivery of health services, this consensus document has been created with the aim of developing recommendations on cretiera for hormone sensitivity and resistance in HER2-negative luminal MBC and facilitating clinical decision-making. Methods: This consensus document was generated using a modification of the RAND/UCLA methodology, which included the definition of the project and identification of issues of interest, a non-exhaustive systematic review of the literature, an analysis and synthesis of the scientific evidence, preparation of recommendations, and external evaluation with a panel of 64 medical oncologists specializing in breast cancer. Results: A Spanish panel of experts reached consensus on 32 of the 32 recommendations/conclusions presented in the first round and were accepted with an approval rate of 100% about definition of metastatic disease not susceptible to local curative treatment, definition of hormone sensitivity and hormone resistance in metastatic luminal disease and therapeutic decision-making. Conclusion: We have developed a consensus document with recommendations on the treatment of patients with HER2-negative luminal MBC that will help to improve therapeutic benefits

Hacia una aplicación efectiva de Metodología Inversa en las asignaturas de Física de primeros cursos de Grado

[ES] En el presente trabajo se presenta la experiencia de la implantación de la docencia inversa en asig-naturas de la materia de física en primeros cursos de las titulaciones de Ingeniería Aeroespacial, Ingeniería Informática e Ingeniería Biomédica. Para obtener la opinión del alumnado se han lle-vado a cabo una serie de encuestas con respuestas abiertas y de opción multiple. Los resultados obtenidos muestran una gran variabilidad de opiniones, incluso dentro del alumnado perteneciente a un mismo grupo. En general los alumnos valoran positivamente el esfuerzo realizado por el pro-fesorado, pero es necesario que los profesores lleven a cabo una serie de medidas para que la implantación de la metodología sea exitosa. Entre ellas, resulta necesario que los contenidos dis-ponibles estén perfectamente estructurados y accesibles, que los contenidos sean interactivos y per-mitan dar información sobre cómo se desarrolla el proceso de aprendizaje, que el nivel de carga de trabajo del alumnado sea sostenible y que el profesorado sea consciente de que la transición en el modelo de aprendizaje requiere de cierta empatía. La implantación de la docencia inversa es por tanto un proceso complejo que requiere una adaptación específica al contexto docente donde se aplica.[EN] En el presente trabajo se presenta la experiencia de la implantación de la docencia inversa en asig-naturas de la materia de física en primeros cursos de las titulaciones de Ingeniería Aeroespacial, Ingeniería Informática e Ingeniería Biomédica. Para obtener la opinión del alumnado se han lle-vado a cabo una serie de encuestas con respuestas abiertas y de opción multiple. Los resultados obtenidos muestran una gran variabilidad de opiniones, incluso dentro del alumnado perteneciente a un mismo grupo. En general los alumnos valoran positivamente el esfuerzo realizado por el pro-fesorado, pero es necesario que los profesores lleven a cabo una serie de medidas para que la implantación de la metodología sea exitosa. Entre ellas, resulta necesario que los contenidos dis-ponibles estén perfectamente estructurados y accesibles, que los contenidos sean interactivos y per-mitan dar información sobre cómo se desarrolla el proceso de aprendizaje, que el nivel de carga de trabajo del alumnado sea sostenible y que el profesorado sea consciente de que la transición en el modelo de aprendizaje requiere de cierta empatía. La implantación de la docencia inversa es por tanto un proceso complejo que requiere una adaptación específica al contexto docente donde se aplica.Gómez Tejedor, JA.; Tort-Ausina, I.; Vidaurre, A.; Meseguer Dueñas, JM.; Molina-Mateo, J.; Riera, J. (2021). Hacia una aplicación efectiva de Metodología Inversa en las asignaturas de Física de primeros cursos de Grado. En IN-RED 2020: VI Congreso de Innovación Educativa y Docencia en Red. Editorial Universitat Politècnica de València. 83-94. https://doi.org/10.4995/INRED2020.2020.11934OCS839