Experimental study on reperfusion of intraocular lens

作者简介: 祁明信, 男, 1945 年7 月 出生, 教授、主任医师、博士研究生 导师, 主要从事白内障的基础与临 床研究。联系电话: 0591-83570887; E-mail:qihuang@netease. com 通讯作者: 黄秀榕,E-mail:[email protected][中文文摘]目的开展晶状体再灌注的离体和动物实验研究,并对再灌注人工晶状体技术进行评价。方法采用新鲜离体幼兔眼、离体猪眼、新西兰白兔眼,应用自行研制的人工晶状体材料,进行以下实验:(1)体外固化实验;(2)晶状体前囊膜微型撕囊及其稳固性实验;(3)经微型前囊膜开口超声乳化吸出晶状体内容物实验;(4)活的新西兰白兔眼内人工晶状体再灌注实验。结果(1)按硅酮聚合物与固化剂50:1的比例可获得柔软、弹性好、固化时间短(完全固化时间为60min)的注入材料;(2)晶状体前囊膜1.8～2.0mm的连续环形撕囊口具有较好的稳定性,可经该微型开口吸出晶状体内容物并灌注材料;(3)超声能量18%、流量25mL·min-1、负压120mmHg(1kPa=7.5mmHg)为晶状体内容物经微型前囊膜开口吸出的最佳条件;(4)注入灌注材料后可形成由晶状体囊膜包裹的、置换原晶状体皮质和核的、新的再灌注人工晶状体。结论采用再灌注人工晶状体的方法可进行新型人工晶状体再灌注,可为治疗白内障和老视提供参考。[英文文摘]Objective To carry out the experimental study on reperfusion of intraocular lens(IOLs) in vitro or in animal,and to assess the technique of IOLs reperfusion.Methods The following experiments were performed by using self-developed materials in fresh rabbit eyes and pig eyes in vitro,as well as in eyes of alive New-Zea-land rabbits:(1)Solidification study of self-developed material in vitro;(2)Continuous circular capsulorhexis(CCC) in anterior capsule of lens and its stability;(3)Draw of lens contents via phaco through mini-CCC;(4)IOLs ref illing in the eyes of alive New-Zea land rabbits. Results(1) Thematerialwhich was soft, springy and short-term solidification(full solidification time was 60 minutes) were obtained in certain proportion of geland solidified agent(50:1) in vitro; ( 2)The CCC in anterior capsule of lens with 1.8-2.0 mm diameter had very good stability. The lens contents were drawn and the materialwere refilled through themini-CCC; (3) The best conditions of drawing out lens contents through m ini-CCC were phaco energy 18% , flow 25 mL·min- 1, and negative pressure 120 mmH g (1kPa=7.5 mmHg);(4) The new refilled IOLs, which were wrapped by capsule of lens and were replaced original cortex and nucleus of lens, were obtained after thematerial refillied. Conc lusion. New IOLs are refilled through this method, which can prov ide reference for the treatment of cataract and presbyopia.福建省科技三项费用;教育厅重点资助项目基金资助(编号:K98041

三角筋で行う筋肉内注射の適切な位置,遺体と生体の腕を比較して

金沢大学 医学部保健学科看護学原著論

A trial manufacturing of a fundus perimeter by which the target automatically pursue eye movement

科学研究費補助金研究成果報告書研究種目: 基盤研究(A)研究期間: 1995～1997課題番号: 07557262研究代表者: 可児 一孝（滋賀医科大学・医学部・教授）研究分担者: 稲富 昭太（滋賀医科大学・医学部・名誉教授）研究分担者: 山出 新一（滋賀医科大学・医学部・助教授）研究分担者: 西田 保裕（滋賀医科大学・医学部・講師）研究分担者: 永田 啓（滋賀医科大学・医学部・講師）研究分担者: 中村 二郎（滋賀医科大学・医学部・助手）研究分担者: 黄野 桃世（滋賀医科大学・医学部・助手）研究分担者: 吉田 健一（滋賀医科大学・医学部・助手）研究分担者: 林 理（滋賀医科大学・医学部・助手）研究分担者: 山田 重喜（滋賀医科大学・医学部・助手

草炭对土壤理化性质及小白菜产量和蛋白质含量影响

本文研究了石河子草炭和加拿大草炭对库尔班通古特沙漠南缘北沙窝普通简育正常干旱土的改良效果和对小白菜生长的影响。结果表明，草炭能改善土壤一些物理性质和化学性质，促进小白菜生长。土壤中加入草炭后土壤的物理性质有较大变化，土壤硬度降低，土壤三相比气相比例增加，固相比例减少，土壤的通气透水性增强；土壤的化学性质也有较大变化，土壤pH值降低，降低了碱性对植物生长胁迫，养分含量发生了变化，全氮，速效氮和水解氮含量增加，淡植物生长提供了氮素营养。而且上述各变化趋势随草炭在土壤中的比例的增加而增大.磷，钾含量变化不大。加拿大草炭碳氮比过高，约为70，小折菜生长过程中有缺氮现象，原因可能是土壤碳氮比高而造成土壤氮素营养植物可用性降低，补充氮肥和磷肥后有明显改善。干旱区保证植物供水是植物生长的重要条件，实验证明在土壤中加入石河子草炭和加拿大草炭能抑制小白菜气孔开启程度，从而提高小白菜的抗旱能力。另外，介质较高的土壤含水量能在一定程度上提高小白菜产量。草品湿重，干重有很大提高。另外，小白菜较大提高。石河子草炭处理盆栽在草炭含量达15%以后增产效率开始降低.加拿大草炭处理土壤A组和B组在草炭含量达2%比例后增产效率开始下降，C组5%比例后才开始下降。通过结论：单独施加草炭改土，与肥料一起施用改土以及不同水分条件下草炭都有一定改土效果，能不同程度上提高小白菜产量，石河子草炭改良土壤的最大比例为15%，加拿大草炭改良土壤的最大比例为2%。至于如何经济，有效地利用草炭在另一篇文章中讨论。另外，以草炭为主的土壤营养调节理已申请专利，中国专利局已受理，申请专利号为98107697.1。The effect of peat on the improvement of ordinary simply developed normal arid soil located in the south of the BeiShaWo, Kurbantonkut Desert was studied together with its effect on the growth of small cabbage. The result shows that peat can improve some physical and chemical properties of the soil. It can also advance the growth of small cabbage. After the addition of peat to the soil, the physical properties of the soil changed a lot, the hardness of the soil lowered, the solid,liquid and gas phase proportion changed with the result that the solid phase proportion decreased and the gas phase proportion increased, so that the aeration and permeability increased; Peat also affects the chemical property a lot. firstly it decreased the soil pH which lowered the coerce of acidity on the growth of the plant. the soil nutrient also changed. The amount of total nitrogen, rapidly available nitrogen, hydrolysable nitrogen increased, providing nitrogen nutrition for the growth of plant. Moreover, the above-mentioned variation trend increases with the addition of more peat to the soil, the amount of phosphor and potassium only have a slight change. The Canadian peat has a much higher C/N which is about 71, it might bring about the competition of nitrogen between plant and microorganisms, The experiment showed that the addition of nitrogen and phosphor fertilizer greatly increased the product of the small cabbage. It is very important to provide sufficient water for the plant in arid areas, the experiment showed that the addition of Shihezi peat and Canadian peat to the soil can lower the openness of plant stoma, improve its ability of coping with the dry condition, In addition, keeping the soil moisture in high level can increase small cabbage product in some degree. Evidently peat can increase the production of cabbage, the dry and wet matter is greatly increased additionally peat can also increase the amount of coarse protein and chlorophyll. The yield of Shihezi Peat treated cabbage become steady at fifteen percent proportion and does not increase with the adding of peat to the soil any more; the production of Canadian peat treated cabbage is highest when two percent peat is added to the soil. From the experiment we got the conclusion that: Treating soil only by peat or together with fertilizer in different water condition can improve the soil in some degree, and increase the yield of small cabbage. the effect of Shihezi peat begin to decrease in 15%, and that of Canadian peat is 2% for A and B group, 5% for C group. According to the experiment we got the following conclusion: either treating soil with peat singly or together with fertilizer, and in different water condition, peat can improve the soil in some degree, and increase the yield of small cabbage, the highest effective proportion of Shihezi peat is 15%, and that of Canadian peat is 2% As far as how to economically and effectively utilize the peat, another paper will discuss it. In addition, patent for Soil nutritious adjusting agent based mainly on peat has been applied for, and its number is 98107697.1

A CASE REPORT OF CAT SCRATCH DISEASE WHICH MIMICKED A METASTASIS OF LUNG CANCER

A 67-year-old woman to our hospital because of the swelling of lymph nodes in the right inguinal region. Eighteen months before, right lower lobectomy was performed for drimary lung cancer (pappillary adenocarcinoma). In September 1986,she noticed the swelling of lymph no des in the right inguinal region and low grade fever. At first she was suspected to have a metastasis of the lung cancer. Lymph node biopsy was performed. The pathological examination revealed purulent lymphadenitis with granulomatous change, and Gram-negative Warthin Starry stainpositive rods were found. In addition, she admitted a history of keeping catsforteen years. Therefore the diagnosis of cat scratch disease was made. Six months later, she became free of the associated symptoms. We feel pathological confirmation of suspicious lymph nodes is important in the treetment of paitients with history of malignancy

脊髄小脳変性症における脳内アセチルコリンエステラーゼ活性変化のＰＥＴによる定量測定

【目的】ＰＥＴにて脊髄小脳変性症（ＳＣＤ）患者の脳内アセチルコリンエステラーゼ（ＡＣｈＥ）活性を測定し、ＳＣＤの病型による相違を検討する。【対象及び方法】多系統萎縮症（ＭＳＡ）８例（５９±４歳（平均±ＳＤ）、Ｍ：Ｆ＝7：1）、Ｍａｃｈａｄｏ-Ｊｏｓｅｐｈ（ＳＣＡ３）５例（５４±７歳、Ｍ：Ｆ＝３：２）、健常対照１３例（５７±１６歳、Ｍ：Ｆ＝９：４）である。〔11Ｃ〕ＭＰ４Ｐ−ＰＥＴを用いて大脳皮質、視床、小脳皮質等の計２７カ所の関心領域においてＫ１とｋ３値を算出した。【結果】ＭＳＡでは健常対照群に比較し、視床、橋、小脳皮質、小脳虫部。で有意にｋ３値が低下していた。ＳＣＡ３では小脳上部皮質でのみ正常に比べ有意なｋ３値低下を認めた。【結論】ＰＥＴによる脳内ＡＣｈＥ活性測定はＳＣＤの評価・鑑別に有用と思われた。第44回日本核医学会総

脳血管性痴呆における脳内コリン神経系について

第42回日本核医学会総